butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Baskova IP et al. | Thrombolytic agents of the preparation from the medicinal leeches. | 1988 | Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. | pmid:2459014 |
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Brass EP and Beyerinck RA | Effects of propionate and carnitine on the hepatic oxidation of short- and medium-chain-length fatty acids. | 1988 | Biochem. J. | pmid:3134008 |
Gladhaug IP et al. | Effects of butyrate on epidermal growth factor receptor binding, morphology, and DNA synthesis in cultured rat hepatocytes. | 1988 | Cancer Res. | pmid:3263190 |
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Kaneko Y et al. | Fibroblast-like transformation and c-myc gene alteration of human hepatocytes induced by novobiocin and butyrate. | 1988 | Biochem. Biophys. Res. Commun. | pmid:2843181 |
Sutherland GR et al. | A BrdU-enhanceable fragile site or viral modification site at 11q23.1 in lymphoblastoid cultures. | 1988 | Cytogenet. Cell Genet. | pmid:2843323 |
Powers AC et al. | Sodium butyrate increases glucagon and insulin gene expression by recruiting immunocytochemically negative cells to produce hormone. | 1988 | Diabetes | pmid:2843409 |
Kisauzi DN and Leek BF | Liver blood flow and volatile fatty acid utilization in sheep before and after carbon tetrachloride treatment. | 1988 | J. Comp. Pathol. | pmid:3417915 |
Bidet M et al. | Role of monocarboxylic acid transport in intracellular pH regulation of isolated proximal cells. | 1988 | Biochim. Biophys. Acta | pmid:3342236 |
Staecker JL and Pitot HC | The effect of sodium butyrate on tyrosine aminotransferase induction in primary cultures of normal adult rat hepatocytes. | 1988 | Arch. Biochem. Biophys. | pmid:2895606 |
Giancotti V et al. | Butyrate effect on nuclear proteins of two Chinese hamster cell lines. | 1988 | Exp. Cell Res. | pmid:3335229 |
Spector R | Fatty acid transport through the blood-brain barrier. | 1988 | J. Neurochem. | pmid:3335863 |
Effects of short-chain fatty acids on a human colon carcinoma cell line. | 1988 | Nutr. Rev. | pmid:3340339 | |
Hallows KR et al. | Effects of the differentiating agents sodium butyrate and N-methylformamide on the oxygen enhancement ratio of human colon tumor cells. | 1988 | Radiat. Res. | pmid:3340722 |
Berry RD and Paraskeva C | Expression of carcinoembryonic antigen by adenoma and carcinoma derived epithelial cell lines: possible marker of tumour progression and modulation of expression by sodium butyrate. | 1988 | Carcinogenesis | pmid:3345582 |
Annunziato AT et al. | Treatment with sodium butyrate inhibits the complete condensation of interphase chromatin. | 1988 | Chromosoma | pmid:3349872 |
Lacroix J et al. | In vitro and in vivo activity of 1-aryl-3-(2-chloroethyl) urea derivatives as new antineoplastic agents. | 1988 Jul-Aug | Anticancer Res. | pmid:3052247 |
Tocco DJ et al. | Disposition and metabolism of sodium 4-[(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl]-gamma -oxobenzenebutanoate in rats and dogs. | 1988 Sep-Oct | Drug Metab. Dispos. | pmid:2906591 |
Tocco DJ et al. | The physiological disposition of aerosolized 4-[(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl]-gamma -oxobenzenebutanoate (L-648,051) in rats. | 1988 Sep-Oct | Drug Metab. Dispos. | pmid:2906592 |
Gonçalves E et al. | Triiodothyronine transport into differentiated and undifferentiated mouse neuroblastoma cells (NB41A3). | 1989 | Endocrinology | pmid:2909368 |
Bägli DJ et al. | Natural killer sensitivity of colorectal carcinoma targets. Correlation with degree of differentiation. | 1989 | Arch Surg | pmid:2910252 |
Corfield AP et al. | Selection of radioactive precursors for metabolic labelling of mucus glycoproteins. | 1989 | Biochem. Soc. Trans. | pmid:2628065 |
Bretton RH and Pennypacker JP | Butyric acid causes morphological changes in cultured chondrocytes through alterations in the extracellular matrix. | 1989 | J. Cell. Physiol. | pmid:2910883 |
Otaka M et al. | Antibody-mediated targeting of differentiation inducers to tumor cells: inhibition of colonic cancer cell growth in vitro and in vivo. A preliminary note. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2912449 |
Brass EP and Garrity MJ | Modulation of prostaglandin E2 catabolism and action by fuel substrates in rat hepatocytes. | 1989 | Biochim. Biophys. Acta | pmid:2912505 |
Vaziri ND et al. | Effect of experimental azotemia on intestinal transport of butyric acid. | 1989 | Proc. Soc. Exp. Biol. Med. | pmid:2915995 |
Higgins PJ and Ryan MP | Biochemical localization of the transformation-sensitive 52 kDa (p52) protein to the substratum contact regions of cultured rat fibroblasts. Butyrate induction, characterization, and quantification of p52 in v-ras transformed cells. | 1989 | Biochem. J. | pmid:2920008 |
Perrine SP et al. | Butyric acid modulates developmental globin gene switching in man and sheep. | 1989 | Adv. Exp. Med. Biol. | pmid:2484761 |
Wiese B and Martin K | Basic extraction studies of benzylpenicillin and its determination by liquid chromatography with pre-column derivatisation. | 1989 | J Pharm Biomed Anal | pmid:2488609 |
Matsuhisa T et al. | Induction of blood coagulation factor VIII by sodium butyrate in Balb/c 3T3 cells. | 1989 | Exp. Cell Res. | pmid:2491813 |
Durie BG et al. | Myelomonocytic myeloma cell line (LB 84-1). | 1989 | Blood | pmid:2492835 |
Dorner AJ et al. | Increased synthesis of secreted proteins induces expression of glucose-regulated proteins in butyrate-treated Chinese hamster ovary cells. | 1989 | J. Biol. Chem. | pmid:2511206 |
Malik Z et al. | Inactivation of erythrocytic, lymphocytic and myelocytic leukemic cells by photoexcitation of endogenous porphyrins. | 1989 | J. Photochem. Photobiol. B, Biol. | pmid:2512381 |
Lehman TA et al. | Metabolism of and DNA adduct formation by benzo[alpha]pyrene in human skin epithelial cells in vitro pretreated with cytochrome P450 modulators. | 1989 | Cancer Biochem. Biophys. | pmid:2515917 |
Knight SC et al. | Lithium and hydrocortisone interactions on cell growth and gene expression in human promyelocytic leukemia (HL60). | 1989 | Leuk. Res. | pmid:2523989 |
Cox GS and Park KH | Modulation of glycoprotein hormone alpha-subunit levels, alkaline phosphatase activity, and DNA replication by antimetabolites in HeLa cultures. | 1989 | Arch. Biochem. Biophys. | pmid:2463791 |
Chatham JC et al. | The metabolic consequences of hydroperoxide perfusion on the isolated rat heart. | 1989 | Eur. J. Biochem. | pmid:2806248 |
Jenkins DJ | The link between colon fermentation and systemic disease. | 1989 | Am. J. Gastroenterol. | pmid:2816871 |
Aizawa K et al. | Placental alkaline phosphatase-like isoenzymes produced by human gastric cancer cells. | 1989 | Acta Pathol. Jpn. | pmid:2686348 |
Tanaka Y et al. | Enhancement of butyrate-induced differentiation of HT-29 human colon carcinoma cells by 1,25-dihydroxyvitamin D3. | 1989 | Biochem. Pharmacol. | pmid:2688649 |
Flatow U et al. | Characterization and tumorigenicity of a butyrate-adapted T24 bladder cancer cell line. | 1989 | Cancer Invest. | pmid:2695227 |
Neogrády Z et al. | Effect of intraruminal butyrate infusion on the plasma insulin level in sheep. | 1989 | Acta Vet. Hung. | pmid:2697146 |
Gardner SL et al. | Modulation by sodium butyrate of the differentiated status of a clonal pancreatic B-cell line (RIN). | 1989 | Diabetes Res. | pmid:2699445 |
Neogrády S et al. | The effects of butyrate and glucagon on the proliferation of ruminal epithelial cells in culture. | 1989 | Vet. Res. Commun. | pmid:2773302 |
Newman JD et al. | Induction of the insulin receptor and other differentiation markers by sodium butyrate in the Burkitt lymphoma cell, Raji. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2786417 |
Kojima S et al. | Identification of myeloid origin in undifferentiated congenital leukemia by in vitro marrow culture study. | 1989 | Am J Pediatr Hematol Oncol | pmid:2782565 |
Goldstein S et al. | Enhanced transfection efficiency and improved cell survival after electroporation of G2/M-synchronized cells and treatment with sodium butyrate. | 1989 | Nucleic Acids Res. | pmid:2786626 |
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Bloom EJ et al. | Effect of sodium butyrate, a differentiating agent, on cell surface glycoconjugates of a human pancreatic cell line. | 1989 | Pancreas | pmid:2717602 |
Aller P et al. | Modification of cell growth-dependent gene transcript levels by sodium butyrate in serum stimulated fibroblasts. | 1989 | Biochem. Int. | pmid:2719709 |
Cheng KJ et al. | The characterization and ultrastructure of two new strains of Butyrivibrio. | 1989 | Can. J. Microbiol. | pmid:2743214 |
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Bohan CA et al. | Mutational analysis of sodium butyrate inducible elements in the human immunodeficiency virus type I long terminal repeat. | 1989 | Virology | pmid:2800338 |
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Furukawa M et al. | [Suppressive effect of CDDP on induction of the Epstein-Barr virus antigen synthesis by n-butyrate]. | 1989 | Nippon Jibiinkoka Gakkai Kaiho | pmid:2545850 |
Iavarone A et al. | 3-D changes in neuroblastoma x glioma hybrid (NG 108-15) cell differentiation as studied by SEM and TEM. | 1989 | Prog. Clin. Biol. Res. | pmid:2546164 |
Herman MM et al. | Neuroblastic differentiation potential of the human retinoblastoma cell lines Y-79 and WERI-Rb1 maintained in an organ culture system. An immunohistochemical, electron microscopic, and biochemical study. | 1989 | Am. J. Pathol. | pmid:2643884 |
Hoessly MC et al. | Factors responsible for variable reported lineages of HL-60 cells induced to mature with butyric acid. | 1989 | Cancer Res. | pmid:2567205 |
Poduslo SE | Induction of ketone body enzymes in glial cells. | 1989 | Arch. Biochem. Biophys. | pmid:2568818 |
Zielke HR et al. | Effect of nerve growth factor on the synthesis of amino acids in PC12 cells. | 1989 | J. Neurosci. Res. | pmid:2569539 |
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Mickley LA et al. | Modulation of the expression of a multidrug resistance gene (mdr-1/P-glycoprotein) by differentiating agents. | 1989 | J. Biol. Chem. | pmid:2572588 |
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Gladhaug IP and Christoffersen T | n-butyrate and dexamethasone synergistically modulate the surface expression of epidermal growth factor receptors in cultured rat hepatocytes. | 1989 | FEBS Lett. | pmid:2646145 |
Hargreaves AJ et al. | Sodium butyrate induces major morphological changes in C6 glioma cells that are correlated with increased synthesis of a spectrin-like protein. | 1989 | Brain Res. Dev. Brain Res. | pmid:2653664 |
Turner BM | Acetylation and deacetylation of histone H4 continue through metaphase with depletion of more-acetylated isoforms and altered site usage. | 1989 | Exp. Cell Res. | pmid:2653852 |
Rome L et al. | Proximal tubule volume regulation in hyperosmotic media: intracellular K+, Na+, and Cl-. | 1989 | Am. J. Physiol. | pmid:2610250 |
Staiano-Coico L et al. | Sodium-N-butyrate induces cytoskeletal rearrangements and formation of cornified envelopes in cultured adult human keratinocytes. | 1989 | Cell Tissue Kinet | pmid:2611852 |
Garrison JC et al. | Computer-based image analysis of cartilage differentiation in embryonic limb bud micromass cultures. | 1989 | J Microsc | pmid:2614818 |
Perrine SP et al. | Butyrate analogues modulate globin gene expression in human and ovine erythroid cells. | 1989 | Prog. Clin. Biol. Res. | pmid:2616579 |
Okabayashi K et al. | Effect of butyrate on the expression of the human preprourokinase gene introduced into Chinese hamster ovary cells. | 1989 | Cell Struct. Funct. | pmid:2620348 |
Kumagai S et al. | [Assessment of occupational exposures to industrial hazardous substances. III. On the frequency distribution of daily exposure averages (8-h TWA)]. | 1989 | Sangyo Igaku | pmid:2585804 |