butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Villain H et al. | HDAC inhibition promotes both initial consolidation and reconsolidation of spatial memory in mice. | 2016 | Sci Rep | pmid:27270584 |
Zhang Q et al. | Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced colitis by a butyrate-producing bacterium. | 2016 | Sci Rep | pmid:27264309 |
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Anderson NA et al. | Synthesis and determination of absolute configuration of a non-peptidic αvβ6 integrin antagonist for the treatment of idiopathic pulmonary fibrosis. | 2016 | Org. Biomol. Chem. | pmid:27226381 |
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Tian H et al. | Anaerobic co-digestion of kitchen waste and pig manure with different mixing ratios. | 2015 | J. Biosci. Bioeng. | pmid:25617184 |
Zheng XT et al. | Sodium butyrate down-regulates tristetraprolin-mediated cyclin B1 expression independent of the formation of processing bodies. | 2015 | Int. J. Biochem. Cell Biol. | pmid:26555753 |
Deng Y et al. | Driving carbon flux through exogenous butyryl-CoA: Acetate CoA-transferase to produce butyric acid at high titer in Thermobifida fusca. | 2015 | J. Biotechnol. | pmid:26535965 |
Durlak M et al. | A Novel High-Content Immunofluorescence Assay as a Tool to Identify at the Single Cell Level γ-Globin Inducing Compounds. | 2015 | PLoS ONE | pmid:26509275 |
Sasajima H et al. | Intranasal administration of rotenone in mice attenuated olfactory functions through the lesion of dopaminergic neurons in the olfactory bulb. | 2015 | Neurotoxicology | pmid:26493152 |
Huang C et al. | Dietary Sodium Butyrate Decreases Postweaning Diarrhea by Modulating Intestinal Permeability and Changing the Bacterial Communities in Weaned Piglets. | 2015 | J. Nutr. | pmid:26491121 |
Nasser Al-Shorgani NK et al. | Improvement of the butanol production selectivity and butanol to acetone ratio (B:A) by addition of electron carriers in the batch culture of a new local isolate of Clostridium acetobutylicum YM1. | 2015 | Anaerobe | pmid:26439644 |
Wang L et al. | Fermentation of sweet sorghum derived sugars to butyric acid at high titer and productivity by a moderate thermophile Clostridium thermobutyricum at 50°C. | 2015 | Bioresour. Technol. | pmid:26432057 |
Moran JK et al. | The Scent of Blood: A Driver of Human Behavior? | 2015 | PLoS ONE | pmid:26397374 |
Imai K et al. | Involvement of Sp1 in butyric acid-induced HIV-1 gene expression. | 2015 | Cell. Physiol. Biochem. | pmid:26383101 |
Pandey K et al. | Histone deacetylase inhibition facilitates massed pattern-induced synaptic plasticity and memory. | 2015 | Learn. Mem. | pmid:26373830 |
Rajendran VM et al. | Na-H Exchanger Isoform-2 (NHE2) Mediates Butyrate-dependent Na+ Absorption in Dextran Sulfate Sodium (DSS)-induced Colitis. | 2015 | J. Biol. Chem. | pmid:26350456 |
Rawłuszko-Wieczorek AA et al. | Effect of DNA methylation profile on OATP3A1 and OATP4A1 transcript levels in colorectal cancer. | 2015 | Biomed. Pharmacother. | pmid:26349991 |
Sobolewski C et al. | Histone Deacetylase Inhibitors Activate Tristetraprolin Expression through Induction of Early Growth Response Protein 1 (EGR1) in Colorectal Cancer Cells. | 2015 | Biomolecules | pmid:26343742 |
Fomina-Yadlin D et al. | Transcriptome analysis of a CHO cell line expressing a recombinant therapeutic protein treated with inducers of protein expression. | 2015 | J. Biotechnol. | pmid:26325199 |
Patman G | Gut microbiota: Lactobacillus acidophilus opens the door to butyrate. | 2015 | Nat Rev Gastroenterol Hepatol | pmid:26323876 |
Desai VH et al. | Receptor-Guided De Novo Design of Dengue Envelope Protein Inhibitors. | 2015 | Appl. Biochem. Biotechnol. | pmid:26299376 |
Kumar A et al. | Lactobacillus acidophilus counteracts enteropathogenic E. coli-induced inhibition of butyrate uptake in intestinal epithelial cells. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:26272259 |
Kumar P et al. | Differential Effects of Sodium Butyrate and Lithium Chloride on Rhesus Monkey Trophoblast Differentiation. | 2015 | PLoS ONE | pmid:26266541 |
Li L et al. | Increased Butyrate Production During Long-Term Fermentation of In Vitro-Digested High Amylose Cornstarch Residues with Human Feces. | 2015 | J. Food Sci. | pmid:26256258 |
Shang HM et al. | Effects of dietary polysaccharides from the submerged fermentation concentrate of Hericium caput-medusae (Bull.:Fr.) Pers. on fat deposition in broilers. | 2015 | J. Sci. Food Agric. | pmid:24771556 |
Bucki R et al. | Bactericidal Activity of Ceragenin CSA-13 in Cell Culture and in an Animal Model of Peritoneal Infection. | 2015 | Antimicrob. Agents Chemother. | pmid:26248361 |
Chen Y et al. | Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice. | 2015 | Cardiovasc Diabetol | pmid:26245924 |
Fukushima A et al. | Ketogenic diet does not impair spatial ability controlled by the hippocampus in male rats. | 2015 | Brain Res. | pmid:26111645 |
Steliou K et al. | Bioprotective carnitinoids: lipoic acid, butyrate, and mitochondria-targeting to treat radiation injury: mitochondrial drugs come of age. | 2015 | Drug Dev. Res. | pmid:26109467 |
Brandão FA et al. | Histone deacetylases inhibitors effects on Cryptococcus neoformans major virulence phenotypes. | 2015 | Virulence | pmid:26103530 |
Sun J et al. | Neuroprotective Effect of Sodium Butyrate against Cerebral Ischemia/Reperfusion Injury in Mice. | 2015 | Biomed Res Int | pmid:26064905 |
Sharma S et al. | Beneficial effects of sodium butyrate in 6-OHDA induced neurotoxicity and behavioral abnormalities: Modulation of histone deacetylase activity. | 2015 | Behav. Brain Res. | pmid:26048426 |
Li H et al. | Administration of progranulin (PGRN) triggers ER stress and impairs insulin sensitivity via PERK-eIF2α-dependent manner. | 2015 | Cell Cycle | pmid:26039714 |
Malago JJ and Sangu CL | Intraperitoneal administration of butyrate prevents the severity of acetic acid colitis in rats. | 2015 | J Zhejiang Univ Sci B | pmid:25743124 |
Sobahan MA et al. | Allyl isothiocyanate induces stomatal closure in Vicia faba. | 2015 | Biosci. Biotechnol. Biochem. | pmid:26027691 |
Lee KM et al. | Butyric acid production from red algae by a newly isolated Clostridium sp. S1. | 2015 | Biotechnol. Lett. | pmid:26026964 |
Jiang L et al. | Thermophilic hydrogen-producing bacteria inhabiting deep-sea hydrothermal environments represented by Caloranaerobacter. | 2015 | Res. Microbiol. | pmid:26026841 |
Agarwal U et al. | Role of rumen butyrate in regulation of nitrogen utilization and urea nitrogen kinetics in growing sheep. | 2015 | J. Anim. Sci. | pmid:26020334 |
Gao F et al. | The Effect of Processing Additives on Energetic Disorder in Highly Efficient Organic Photovoltaics: A Case Study on PBDTTT-C-T:PC71 BM. | 2015 | Adv. Mater. Weinheim | pmid:26016473 |
Levy AW et al. | Effect of feeding an encapsulated source of butyric acid (ButiPEARL) on the performance of male Cobb broilers reared to 42 d of age. | 2015 | Poult. Sci. | pmid:26015588 |
Liu H et al. | Post-occlusion administration of sodium butyrate attenuates cognitive impairment in a rat model of chronic cerebral hypoperfusion. | 2015 | Pharmacol. Biochem. Behav. | pmid:26013850 |
Chaturvedi K et al. | Oral insulin delivery using deoxycholic acid conjugated PEGylated polyhydroxybutyrate co-polymeric nanoparticles. | 2015 | Nanomedicine (Lond) | pmid:26008194 |
Theparambil SM et al. | Reversed electrogenic sodium bicarbonate cotransporter 1 is the major acid loader during recovery from cytosolic alkalosis in mouse cortical astrocytes. | 2015 | J. Physiol. (Lond.) | pmid:25990710 |
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Conlon MA et al. | Lowering of large bowel butyrate levels in healthy populations is unlikely to be beneficial. | 2015 | J. Nutr. | pmid:25934666 |
Steckert AV et al. | Effects of sodium butyrate on aversive memory in rats submitted to sepsis. | 2015 | Neurosci. Lett. | pmid:25888815 |
Mackmull MT et al. | Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs). | 2015 | Mol. Cell Proteomics | pmid:25755299 |
Cho JH et al. | MicroRNA-31 is a transcriptional target of histone deacetylase inhibitors and a regulator of cellular senescence. | 2015 | J. Biol. Chem. | pmid:25737447 |
Walsh ME et al. | Butyrate prevents muscle atrophy after sciatic nerve crush. | 2015 | Muscle Nerve | pmid:25727783 |
Kowalski ZM et al. | Effect of microencapsulated sodium butyrate in the close-up diet on performance of dairy cows in the early lactation period. | 2015 | J. Dairy Sci. | pmid:25726104 |
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Bianchi N et al. | Erythroid differentiation ability of butyric acid analogues: identification of basal chemical structures of new inducers of foetal haemoglobin. | 2015 | Eur. J. Pharmacol. | pmid:25701725 |
Tan W et al. | Sodium butyrate-induced histone hyperacetylation up-regulating WT1 expression in porcine kidney fibroblasts. | 2015 | Biotechnol. Lett. | pmid:25700826 |
Zhang T et al. | Sodium Butyrate Reduces Organ Injuries in Mice with Severe Acute Pancreatitis Through Inhibiting HMGB1 Expression. | 2015 | Dig. Dis. Sci. | pmid:25686746 |
Wanat P et al. | Short communication: Effect of inclusion rate of microencapsulated sodium butyrate in starter mixture for dairy calves. | 2015 | J. Dairy Sci. | pmid:25648817 |
Gerace E et al. | Interplay between histone acetylation/deacetylation and poly(ADP-ribosyl)ation in the development of ischemic tolerance in vitro. | 2015 | Neuropharmacology | pmid:25623965 |
Li L et al. | Histone deacetylase inhibitor sodium butyrate suppresses DNA double strand break repair induced by etoposide more effectively in MCF-7 cells than in HEK293 cells. | 2015 | BMC Biochem. | pmid:25592494 |
Henagan TM et al. | Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning. | 2015 | Br. J. Pharmacol. | pmid:25559882 |
Weaver EM et al. | Regulation of T-type calcium channel expression by sodium butyrate in prostate cancer cells. | 2015 | Eur. J. Pharmacol. | pmid:25557765 |
Arai T et al. | Actinomyces naeslundii GroEL-dependent initial attachment and biofilm formation in a flow cell system. | 2015 | J. Microbiol. Methods | pmid:25555820 |
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Shimizu T et al. | Volume-sensitive outwardly rectifying Cl(-) channels contribute to butyrate-triggered apoptosis of murine colonic epithelial MCE301 cells. | 2015 | J Physiol Sci | pmid:25544596 |
Huang C et al. | Evaluating the possibility of using acetone-butanol-ethanol (ABE) fermentation wastewater for bacterial cellulose production by Gluconacetobacter xylinus. | 2015 | Lett. Appl. Microbiol. | pmid:25615895 |
Ledaki I et al. | Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition. | 2015 | Oncotarget | pmid:26305601 |
Tiwari P et al. | Combinatorial chemopreventive effect of butyric acid, nicotinamide and calcium glucarate against the 7,12-dimethylbenz(a)anthracene induced mouse skin tumorigenesis attained by enhancing the induction of intrinsic apoptotic events. | 2015 | Chem. Biol. Interact. | pmid:25478867 |
Lopes-Borges J et al. | Histone deacetylase inhibitors reverse manic-like behaviors and protect the rat brain from energetic metabolic alterations induced by ouabain. | 2015 | Pharmacol. Biochem. Behav. | pmid:25433326 |
Agostini S et al. | Barley beta-glucan promotes MnSOD expression and enhances angiogenesis under oxidative microenvironment. | 2015 | J. Cell. Mol. Med. | pmid:25388628 |
Barichello T et al. | Sodium Butyrate Prevents Memory Impairment by Re-establishing BDNF and GDNF Expression in Experimental Pneumococcal Meningitis. | 2015 | Mol. Neurobiol. | pmid:25284351 |
Mátis G et al. | Effects of oral butyrate application on insulin signaling in various tissues of chickens. | 2015 | Domest. Anim. Endocrinol. | pmid:25240231 |
Esteras N et al. | G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients. | 2015 | Mol. Neurobiol. | pmid:25182869 |
Simon-O'Brien E et al. | The histone deacetylase inhibitor sodium butyrate decreases excessive ethanol intake in dependent animals. | 2015 | Addict Biol | pmid:25041570 |
Cottier F et al. | MIG1 Regulates Resistance of Candida albicans against the Fungistatic Effect of Weak Organic Acids. | 2015 | Eukaryotic Cell | pmid:26297702 |
Yoo DY et al. | Sodium butyrate, a histone deacetylase Inhibitor, ameliorates SIRT2-induced memory impairment, reduction of cell proliferation, and neuroblast differentiation in the dentate gyrus. | 2015 | Neurol. Res. | pmid:24963697 |
Dengler F et al. | Both butyrate incubation and hypoxia upregulate genes involved in the ruminal transport of SCFA and their metabolites. | 2015 | J Anim Physiol Anim Nutr (Berl) | pmid:24804847 |
Chen F et al. | Unusual effects of monocarboxylic acids on the structure and on the transport and mechanical properties of chitosan films. | 2015 | Carbohydr Polym | pmid:26256366 |
Park SO and Park BS | Bifidogenic effect of grain larvae extract on serum lipid, glucose and intestinal microflora in rats. | 2015 | J. Biosci. | pmid:26333397 |
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