butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Shi SL et al. | Effects of tachyplesin and n-sodium butyrate on proliferation and gene expression of human gastric adenocarcinoma cell line BGC-823. | 2006 | World J. Gastroenterol. | pmid:16586536 |
Chiang YW et al. | Efficient expression of histidine-tagged large hepatitis delta antigen in baculovirus-transduced baby hamster kidney cells. | 2006 | World J. Gastroenterol. | pmid:16570347 |
Yin HY et al. | Baculovirus vector-mediated transfer of NIS gene into colon tumor cells for radionuclide therapy. | 2010 | World J. Gastroenterol. | pmid:21072902 |
Zhang ZH et al. | Targeting cyclooxygenase-2 with sodium butyrate and NSAIDs on colorectal adenoma/carcinoma cells. | 2004 | World J. Gastroenterol. | pmid:15378772 |
Roda A et al. | A new oral formulation for the release of sodium butyrate in the ileo-cecal region and colon. | 2007 | World J. Gastroenterol. | pmid:17373743 |
Schneider SM et al. | Effects of Saccharomyces boulardii on fecal short-chain fatty acids and microflora in patients on long-term total enteral nutrition. | 2005 | World J. Gastroenterol. | pmid:16273644 |
Chen YX et al. | Histone acetylation regulates p21WAF1 expression in human colon cancer cell lines. | 2004 | World J. Gastroenterol. | pmid:15309711 |
Tedelind S et al. | Anti-inflammatory properties of the short-chain fatty acids acetate and propionate: a study with relevance to inflammatory bowel disease. | 2007 | World J. Gastroenterol. | pmid:17569118 |
He L et al. | Possible mechanism for the regulation of glucose on proliferation, inhibition and apoptosis of colon cancer cells induced by sodium butyrate. | 2007 | World J. Gastroenterol. | pmid:17663521 |
Canani RB et al. | Potential beneficial effects of butyrate in intestinal and extraintestinal diseases. | 2011 | World J. Gastroenterol. | pmid:21472114 |
Pacheco RG et al. | Use of butyrate or glutamine in enema solution reduces inflammation and fibrosis in experimental diversion colitis. | 2012 | World J. Gastroenterol. | pmid:22969190 |
Yan J and Xu YH | Tributyrin inhibits human gastric cancer SGC-7901 cell growth by inducing apoptosis and DNA synthesis arrest. | 2003 | World J. Gastroenterol. | pmid:12679905 |
Kanauchi O et al. | Eubacterium limosum ameliorates experimental colitis and metabolite of microbe attenuates colonic inflammatory action with increase of mucosal integrity. | 2006 | World J. Gastroenterol. | pmid:16534848 |
Zhou D et al. | Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier. | 2017 | World J. Gastroenterol. | pmid:28104981 |
Zhang HQ et al. | Therapeutic effects of Clostridium butyricum on experimental colitis induced by oxazolone in rats. | 2009 | World J. Gastroenterol. | pmid:19370778 |
Shivshankar P and Devi SC | Screening of stimulatory effects of dietary risk factors on mouse intestinal cell kinetics. | 2005 | World J. Gastroenterol. | pmid:15633224 |
Kobori A et al. | Butyrate stimulates IL-32alpha expression in human intestinal epithelial cell lines. | 2010 | World J. Gastroenterol. | pmid:20480520 |
Yamawaki Y et al. | Antidepressant-like effect of sodium butyrate (HDAC inhibitor) and its molecular mechanism of action in the rat hippocampus. | 2012 | World J. Biol. Psychiatry | pmid:21812623 |
Cho HJ et al. | The combination effect of sodium butyrate and 5-Aza-2'-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines. | 2009 | World J Surg Oncol | pmid:19460134 |
Chen Y et al. | In vitro and in vivo double-enhanced suicide gene therapy mediated by generation 5 polyamidoamine dendrimers for PC-3 cell line. | 2012 | World J Surg Oncol | pmid:22226139 |