butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Facial Injuries D005151 1 associated lipids
Gastrinoma D015408 1 associated lipids
Myoepithelioma D009208 1 associated lipids
Proctitis D011349 1 associated lipids
Diverticulitis D004238 1 associated lipids
Salivary Gland Neoplasms D012468 1 associated lipids
Astigmatism D001251 1 associated lipids
Anaplasia D000708 1 associated lipids
Trophoblastic Neoplasms D014328 1 associated lipids
Diverticulitis, Colonic D004239 1 associated lipids
Aphakia, Postcataract D001036 1 associated lipids
Diverticulosis, Colonic D043963 1 associated lipids
Nevus D009506 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Urea Cycle Disorders, Inborn D056806 2 associated lipids
Glycogen Storage Disease Type II D006009 2 associated lipids
Intestinal Neoplasms D007414 2 associated lipids
Hemorrhoids D006484 2 associated lipids
Lymphoma, AIDS-Related D016483 2 associated lipids
Sarcoma, Avian D001357 2 associated lipids
Dentin, Secondary D003809 2 associated lipids
Colorectal Neoplasms, Hereditary Nonpolyposis D003123 2 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Pregnancy in Diabetics D011254 3 associated lipids
Nose Neoplasms D009669 3 associated lipids
Retinal Neoplasms D019572 3 associated lipids
Prostatic Neoplasms, Castration-Resistant D064129 3 associated lipids
Pouchitis D019449 3 associated lipids
Adenocarcinoma, Follicular D018263 3 associated lipids
Psychophysiologic Disorders D011602 3 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Hypereosinophilic Syndrome D017681 3 associated lipids
Epstein-Barr Virus Infections D020031 3 associated lipids
Nasopharyngeal Neoplasms D009303 4 associated lipids
Retroviridae Infections D012192 4 associated lipids
Milk Hypersensitivity D016269 4 associated lipids
Multiple Chemical Sensitivity D018777 4 associated lipids
Dysentery D004403 4 associated lipids
Disease Models, Animal D004195 4 associated lipids
Marek Disease D008380 4 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Herpesviridae Infections D006566 4 associated lipids
Fragile X Syndrome D005600 5 associated lipids
Neoplastic Cells, Circulating D009360 5 associated lipids
Strongylida Infections D017206 5 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Dental Leakage D003763 5 associated lipids
Xeroderma Pigmentosum D014983 6 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Ataxia Telangiectasia D001260 6 associated lipids
Laryngeal Neoplasms D007822 7 associated lipids
Leukemia, Megakaryoblastic, Acute D007947 7 associated lipids
Dementia, Vascular D015140 7 associated lipids
Teratocarcinoma D018243 7 associated lipids
Genomic Instability D042822 7 associated lipids
Phenylketonurias D010661 7 associated lipids
Rhabdomyosarcoma D012208 7 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Constipation D003248 8 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Thalassemia D013789 8 associated lipids
Mast-Cell Sarcoma D012515 9 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Lymphatic Metastasis D008207 10 associated lipids
Hepatoblastoma D018197 10 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Hyperkinesis D006948 11 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Retinoblastoma D012175 12 associated lipids
Acidosis D000138 13 associated lipids
Ketosis D007662 13 associated lipids
Corneal Diseases D003316 13 associated lipids
Radiation Injuries D011832 14 associated lipids
Periodontal Diseases D010510 15 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Lymphoma D008223 18 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Carcinoma, Ductal, Breast D018270 19 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
HIV Infections D015658 20 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Poultry Diseases D011201 21 associated lipids
Sarcoma 180 D012510 21 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Periodontitis D010518 22 associated lipids
Medulloblastoma D008527 22 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Cattle Diseases D002418 24 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Brain Diseases D001927 27 associated lipids
Angina Pectoris D000787 27 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

Download all related citations
Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Xu J et al. Effects of Early Intervention with Sodium Butyrate on Gut Microbiota and the Expression of Inflammatory Cytokines in Neonatal Piglets. 2016 PLoS ONE pmid:27611998
Kotantaki P and Mosialos G The expression of tumor suppressor gene Cyld is upregulated by histone deacetylace inhibitors in human hepatocellular carcinoma cell lines. 2016 Cell Biochem. Funct. pmid:27570065
Ávila M et al. Application of high pressure processing for controlling Clostridium tyrobutyricum and late blowing defect on semi-hard cheese. 2016 Food Microbiol. pmid:27554159
Walia K et al. Effect of feeding sodium butyrate in the late finishing period on Salmonella carriage, seroprevalence, and growth of finishing pigs. 2016 Prev. Vet. Med. pmid:27544256
Otto A et al. The protein inventory of Clostridium difficile grown in complex and minimal medium. 2016 Proteomics Clin Appl pmid:27511832
Yin F et al. Transcriptome Analysis Reveals Regulation of Gene Expression for Lipid Catabolism in Young Broilers by Butyrate Glycerides. 2016 PLoS ONE pmid:27508934
Moore JB et al. The Epigenetic Regulator HDAC1 Modulates Transcription of a Core Cardiogenic Program in Human Cardiac Mesenchymal Stromal Cells Through a p53-Dependent Mechanism. 2016 Stem Cells pmid:27501845
Lakhter AJ et al. Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth. 2016 J. Biol. Chem. pmid:27539851
Fialova B et al. Epigenetic modulation of AR gene expression in prostate cancer DU145 cells with the combination of sodium butyrate and 5'-Aza-2'-deoxycytidine. 2016 Oncol. Rep. pmid:27499010
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Longpré J et al. Impact of mash feeding versus pellets on propionic/butyric acid levels and on total load in the gastrointestinal tract of growing pigs. 2016 J. Anim. Sci. pmid:27065267
Moreno FS et al. Nutritional Epigenetics and the Prevention of Hepatocellular Carcinoma with Bioactive Food Constituents. 2016 Nutr Cancer pmid:27266713
Aguilar EC et al. Oral butyrate reduces oxidative stress in atherosclerotic lesion sites by a mechanism involving NADPH oxidase down-regulation in endothelial cells. 2016 J. Nutr. Biochem. pmid:27261536
Zeng J et al. Autophagy regulates biliary differentiation of hepatic progenitor cells through Notch1 signaling pathway. 2016 Cell Cycle pmid:27259983
Wang A et al. Sodium butyrate mitigates in vitro ammonia generation in cecal content of laying hens. 2016 Environ Sci Pollut Res Int pmid:27154844
Kapuvári B et al. Improved in vivo antitumor effect of a daunorubicin - GnRH-III bioconjugate modified by apoptosis inducing agent butyric acid on colorectal carcinoma bearing mice. 2016 Invest New Drugs pmid:27146514
Wu Y et al. Influence of Butyrate Loaded Clinoptilolite Dietary Supplementation on Growth Performance, Development of Intestine and Antioxidant Capacity in Broiler Chickens. 2016 PLoS ONE pmid:27104860
Rivera-Chávez F et al. Depletion of Butyrate-Producing Clostridia from the Gut Microbiota Drives an Aerobic Luminal Expansion of Salmonella. 2016 Cell Host Microbe pmid:27078066
Lazarova DL and Bordonaro M Vimentin, colon cancer progression and resistance to butyrate and other HDACis. 2016 J. Cell. Mol. Med. pmid:27072512
Zhu P et al. [Effect and mechanism of inhibition of lipopolysaccharide-induced pulmonary fibrosis by butyric acid]. 2016 Zhonghua Wei Zhong Bing Ji Jiu Yi Xue pmid:26805528
Sayed M et al. Selective oxidation of trimethylolpropane to 2,2-bis(hydroxymethyl)butyric acid using growing cells of Corynebacterium sp. ATCC 21245. 2016 J. Biotechnol. pmid:26804932
Zhang J et al. Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for Apoptosis. 2016 PLoS ONE pmid:26784903
Cang S et al. Hypoacetylation, hypomethylation, and dephosphorylation of H2B histones and excessive histone deacetylase activity in DU-145 prostate cancer cells. 2016 J Hematol Oncol pmid:26759222
Kaczmarek SA et al. Effect of different doses of coated butyric acid on growth performance and energy utilization in broilers. 2016 Poult. Sci. pmid:26740137
Jung JM et al. Pseudo catalytic transformation of volatile fatty acids into fatty acid methyl esters. 2016 Bioresour. Technol. pmid:26720136
Xin F et al. Strategies for production of butanol and butyl-butyrate through lipase-catalyzed esterification. 2016 Bioresour. Technol. pmid:26710347
Cibis KG et al. Isolation of acetic, propionic and butyric acid-forming bacteria from biogas plants. 2016 J. Biotechnol. pmid:26779817
Silva FT et al. Replacement of sugars to hydrogen production by Rhodobacter capsulatus using dark fermentation effluent as substrate. 2016 Bioresour. Technol. pmid:26476167
Cueno ME and Ochiai K Re-discovering periodontal butyric acid: New insights on an old metabolite. 2016 Microb. Pathog. pmid:26466516
Russo R et al. Sodium butyrate and its synthetic amide derivative modulate nociceptive behaviors in mice. 2016 Pharmacol. Res. pmid:26675718
Rumpagaporn P et al. Elevated propionate and butyrate in fecal ferments of hydrolysates generated by oxalic acid treatment of corn bran arabinoxylan. 2016 Food Funct pmid:27841429
Liu Y et al. Dietary resistant starch type 4-derived butyrate attenuates nuclear factor-kappa-B1 through modulation of histone H3 trimethylation at lysine 27. 2016 Food Funct pmid:27713965
Zhang Y et al. Monitoring Intracellular pH Change with a Genetically Encoded and Ratiometric Luminescence Sensor in Yeast and Mammalian Cells. 2016 Methods Mol. Biol. pmid:27424899
Villain H et al. HDAC inhibition promotes both initial consolidation and reconsolidation of spatial memory in mice. 2016 Sci Rep pmid:27270584
Zhang Q et al. Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced colitis by a butyrate-producing bacterium. 2016 Sci Rep pmid:27264309
Xiong H et al. Butyrate upregulates endogenous host defense peptides to enhance disease resistance in piglets via histone deacetylase inhibition. 2016 Sci Rep pmid:27230284
Anderson NA et al. Synthesis and determination of absolute configuration of a non-peptidic αvβ6 integrin antagonist for the treatment of idiopathic pulmonary fibrosis. 2016 Org. Biomol. Chem. pmid:27226381
Subramanian U et al. Retinoic acid and sodium butyrate suppress the cardiac expression of hypertrophic markers and proinflammatory mediators in Npr1 gene-disrupted haplotype mice. 2016 Physiol. Genomics pmid:27199456
Bastiaansen JA et al. Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate. 2016 Sci Rep pmid:27150735
Seki K et al. Varying butyric acid amounts induce different stress- and cell death-related signals in nerve growth factor-treated PC12 cells: implications in neuropathic pain absence during periodontal disease progression. 2016 Apoptosis pmid:26994613
Zhang Z et al. O-Linked N-Acetylglucosamine (O-GlcNAc) Transferase and O-GlcNAcase Interact with Mi2β Protein at the Aγ-Globin Promoter. 2016 J. Biol. Chem. pmid:27231347
Vazquez-DeRose J et al. Hypocretin/orexin antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain. 2016 Brain Struct Funct pmid:25431268
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Endesfelder D et al. Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production. 2016 Microbiome pmid:27114075
Kulcsár A et al. Effects of butyrate on the insulin homeostasis of chickens kept on maize- or wheat-based diets. 2016 Acta Vet. Hung. pmid:27993103
Park MJ and Sohrabji F The histone deacetylase inhibitor, sodium butyrate, exhibits neuroprotective effects for ischemic stroke in middle-aged female rats. 2016 J Neuroinflammation pmid:27905989
Gallo A et al. Relationships among ensiling, nutritional, fermentative, microbiological traits and contamination in corn silages addressed with partial least squares regression. 2016 J. Anim. Sci. pmid:27898868
Estensoro I et al. Dietary Butyrate Helps to Restore the Intestinal Status of a Marine Teleost (Sparus aurata) Fed Extreme Diets Low in Fish Meal and Fish Oil. 2016 PLoS ONE pmid:27898676
Chang MC et al. Effect of Butyrate on Collagen Expression, Cell Viability, Cell Cycle Progression and Related Proteins Expression of MG-63 Osteoblastic Cells. 2016 PLoS ONE pmid:27893752
Zhang T et al. Sodium Butyrate Reduces Colitogenic Immunoglobulin A-Coated Bacteria and Modifies the Composition of Microbiota in IL-10 Deficient Mice. 2016 Nutrients pmid:27886121