butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Van Lier JB et al. | Effects of acetate, propionate, and butyrate on the thermophilic anaerobic degradation of propionate by methanogenic sludge and defined cultures. | 1993 | Appl. Environ. Microbiol. | pmid:8476278 |
Lea MA et al. | Butyramide and monobutyrin: growth inhibitory and differentiating agents. | 1993 Jan-Feb | Anticancer Res. | pmid:8476205 |
Gill RK and Christakos S | Identification of sequence elements in mouse calbindin-D28k gene that confer 1,25-dihydroxyvitamin D3- and butyrate-inducible responses. | 1993 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8464915 |
Iwai SA et al. | Changes in Hox1.6, c-jun, and Oct-3 gene expressions are associated with teratocarcinoma F9 cell differentiation in three different ways of induction. | 1993 | Exp. Cell Res. | pmid:8453995 |
Utesch D et al. | Effects of sodium butyrate on DNA content, glutathione S-transferase activities, cell morphology and growth characteristics of rat liver nonparenchymal epithelial cells in vitro. | 1993 | Carcinogenesis | pmid:8453722 |
Saito H et al. | Effect of butyric acid on induction of differentiation into eosinophil-like cells in human eosinophilic leukemia cells, EoL-1 cell line: possible role of granulocyte-macrophage colony-stimulating factor as an autocrine differentiating factor. | 1993 | Int. Arch. Allergy Immunol. | pmid:8453311 |
Gálfi P et al. | Influences of extracellular matrix components on the growth and differentiation of ruminal epithelial cells in primary culture. | 1993 | Res. Vet. Sci. | pmid:8434137 |
Gerharz CD et al. | Modulation of invasive potential in different clonal subpopulations of a rat rhabdomyosarcoma cell line (BA-HAN-1) by differentiation induction. | 1993 | Clin. Exp. Metastasis | pmid:8422707 |
Blau CA et al. | Fetal hemoglobin induction with butyric acid: efficacy and toxicity. | 1993 | Blood | pmid:8422469 |
Herz F | Divergent effects of butyrate on the alkaline phosphatases of SW-620 cells. | 1993 | Biochim. Biophys. Acta | pmid:8422435 |
Sommerville J et al. | Histone H4 acetylation and transcription in amphibian chromatin. | 1993 | J. Cell Biol. | pmid:8421048 |
Dohi T et al. | Induction of the fundic mucosa-specific glycolipid with dimethylformamide in gastric-cancer cell lines. | 1993 | Int. J. Cancer | pmid:8416198 |
Diener M et al. | Effect of short-chain fatty acids on cell volume and intracellular pH in rat distal colon. | 1993 | Pflugers Arch. | pmid:8414909 |
Wischmeyer P et al. | Chronic pouchitis after ileal pouch-anal anastomosis: responses to butyrate and glutamine suppositories in a pilot study. | 1993 | Mayo Clin. Proc. | pmid:8412364 |
Polack A et al. | Regulatory elements in the immunoglobulin kappa locus induce c-myc activation and the promoter shift in Burkitt's lymphoma cells. | 1993 | EMBO J. | pmid:8404859 |
Salvador V et al. | Sugar composition of dietary fibre and short-chain fatty acid production during in vitro fermentation by human bacteria. | 1993 | Br. J. Nutr. | pmid:8399101 |
Hague A et al. | Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer. | 1993 | Int. J. Cancer | pmid:8397167 |
Telfer JF and Green CD | Placental alkaline phosphatase activity is inversely related to cell growth rate in HeLaS3 cervical cancer cells. | 1993 | FEBS Lett. | pmid:8396040 |
Rius C et al. | Differential modulation of the expression of the intermediate filament proteins vimentin and nuclear lamins A and C by differentiation inducers in human myeloid leukemia (U-937, HL-60) cells. | 1993 | Exp. Cell Res. | pmid:8395394 |
Khan MZ et al. | Induction of phenotypic changes in SCLC cell lines in vitro by hexamethylene bisacetamide, sodium butyrate, and cyclic AMP. | 1993 | Ann. Oncol. | pmid:8394737 |
Sakamoto K et al. | Relative mitogenic activities of wild-type and retinoblastoma binding-defective SV40 T antigens in serum-deprived and senescent human diploid fibroblasts. | 1993 | Oncogene | pmid:8390037 |
Wind JC et al. | Stimulation of calcitonin/CGRP-I and CGRP-II gene expression by dibutyryl cAMP in a human medullary thyroid carcinoma (TT) cell line. | 1993 | Mol. Cell. Endocrinol. | pmid:8386116 |
Datti A and Dennis JW | Regulation of UDP-GlcNAc:Gal beta 1-3GalNAc-R beta 1-6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) in Chinese hamster ovary cells. | 1993 | J. Biol. Chem. | pmid:8383671 |
Gaudet SJ et al. | Differential regulation of arylamine and arylalkylamine N-acetyltransferases in human retinoblastoma (Y-79) cells. | 1993 | Neurochem. Int. | pmid:8382984 |
Darcy-Vrillon B et al. | Metabolic characteristics of pig colonocytes after adaptation to a high fiber diet. | 1993 | J. Nutr. | pmid:8381478 |
Heruth DP et al. | Sodium butyrate causes an increase in the block to transcriptional elongation in the c-myc gene in SW837 rectal carcinoma cells. | 1993 | J. Biol. Chem. | pmid:8376401 |
Griner RD et al. | The role of short chain fatty acid substrates in aerobic and glycolytic metabolism in primary cultures of renal proximal tubule cells. | 1993 | In Vitro Cell. Dev. Biol. Anim. | pmid:8376317 |
Nishina Y et al. | The induction of jun genes during the reversible changes induced with sodium butyrate on the differentiation of F9 cells. | 1993 | Exp. Cell Res. | pmid:8375477 |
Barnard JA and Warwick G | Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells. | 1993 | Cell Growth Differ. | pmid:8373733 |
Laughlin MA et al. | Sodium butyrate treatment of cells latently infected with HIV-1 results in the expression of unspliced viral RNA. | 1993 | Virology | pmid:8372431 |
Schmidt JE and Ahring BK | Effects of hydrogen and formate on the degradation of propionate and butyrate in thermophilic granules from an upflow anaerobic sludge blanket reactor. | 1993 | Appl. Environ. Microbiol. | pmid:8368842 |
Wiekowski M et al. | Requirements for promoter activity in mouse oocytes and embryos distinguish paternal pronuclei from maternal and zygotic nuclei. | 1993 | Dev. Biol. | pmid:8365573 |
Calabresse C et al. | Butyric acid and its monosaccharide ester induce apoptosis in the HL-60 cell line. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8363611 |
Mollinedo F et al. | Differences in expression of transcription factor AP-1 in human promyelocytic HL-60 cells during differentiation towards macrophages versus granulocytes. | 1993 | Biochem. J. | pmid:8363564 |
Taggart M and Wray S | Simultaneous measurement of intracellular pH and contraction in uterine smooth muscle. | 1993 | Pflugers Arch. | pmid:8351202 |
Murray NR et al. | Protein kinase C isotypes in human erythroleukemia (K562) cell proliferation and differentiation. Evidence that beta II protein kinase C is required for proliferation. | 1993 | J. Biol. Chem. | pmid:8340409 |
Cremer JE et al. | The influence of portocaval anastomosis on the metabolism of labelled octanoate, butyrate and leucine in rat brain. | 1977 | J. Neurochem. | pmid:833594 |
Komatsu N et al. | Establishment and characterization of an erythropoietin-dependent subline, UT-7/Epo, derived from human leukemia cell line, UT-7. | 1993 | Blood | pmid:8329702 |
Souleimani A and Asselin C | Regulation of c-myc expression by sodium butyrate in the colon carcinoma cell line Caco-2. | 1993 | FEBS Lett. | pmid:8325387 |
Bartram HP et al. | Proliferation of human colonic mucosa as an intermediate biomarker of carcinogenesis: effects of butyrate, deoxycholate, calcium, ammonia, and pH. | 1993 | Cancer Res. | pmid:8324739 |
Chapman MA et al. | Butyrate oxidation is impaired in the colonic mucosa of sufferers of quiescent ulcerative colitis. | 1994 | Gut | pmid:8307454 |
Yabushita H and Sartorelli AC | Effects of sodium butyrate, dimethylsulfoxide and dibutyryl cAMP on the poorly differentiated ovarian adenocarcinoma cell line AMOC-2. | 1993 | Oncol. Res. | pmid:8305743 |
Steinhart AH et al. | Treatment of refractory ulcerative proctosigmoiditis with butyrate enemas. | 1994 | Am. J. Gastroenterol. | pmid:8304299 |
Fernandez-Mejia C and Davidson MB | Effect of sodium butyrate on glucose transport and glucose-phosphorylating enzymes in RIN-m5F cells. | 1993 | Pancreas | pmid:8302795 |
Dong QG et al. | Isolation of a mitomycin-resistant human lung adenocarcinoma cell subline to investigate the modulation by sodium butyrate of cell growth and drug resistance. | 1993 | Anticancer Drugs | pmid:8298162 |
Carraro S et al. | [Influence of sodium butyrate intake on murine colonic carcinogenesis]. | 1993 | Medicina (B Aires) | pmid:8295530 |
Iwami K and Moriyama T | Effects of short chain fatty acid, sodium butyrate, on osteoblastic cells and osteoclastic cells. | 1993 | Int. J. Biochem. | pmid:8288032 |
Roediger WE et al. | Sulphide impairment of substrate oxidation in rat colonocytes: a biochemical basis for ulcerative colitis? | 1993 | Clin. Sci. | pmid:8287651 |
Sperker B et al. | The expression of human plasma cholesteryl-ester-transfer protein in HepG2 cells is induced by sodium butyrate. Quantification of low mRNA levels by polymerase chain reaction. | 1993 | Eur. J. Biochem. | pmid:8281947 |
Hague A et al. | Escape from negative regulation of growth by transforming growth factor beta and from the induction of apoptosis by the dietary agent sodium butyrate may be important in colorectal carcinogenesis. | 1993 | Cancer Metastasis Rev. | pmid:8281610 |