butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gruchlik A et al. | Influence of troglitazone, sodium butyrate, 5-aminosalicylic acid and BAY 11-7082 on the chemokine ENA-78/CXCL5 secretion in the intestinal subepithelial myofibroblasts. | Acta Pol Pharm | pmid:21229889 | |
Kim JS et al. | High-level scu-PA production by butyrate-treated serum-free culture of recombinant CHO cell line. | Biotechnol. Prog. | pmid:15575713 | |
González-Pajuelo M et al. | Metabolic engineering of Clostridium acetobutylicum for the industrial production of 1,3-propanediol from glycerol. | Metab. Eng. | pmid:16095939 | |
Kien CL et al. | Effects of the in vivo supply of butyrate on histone acetylation of cecum in piglets. | JPEN J Parenter Enteral Nutr | pmid:18165447 | |
Roy MJ et al. | In vitro studies on the inhibition of colon cancer by butyrate and carnitine. | Nutrition | pmid:19619983 | |
Nabandith V et al. | Inhibitory effects of crude alpha-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat. | Asian Pac. J. Cancer Prev. | pmid:15546251 | |
Usenko TN et al. | [Transformation with the E1A + cHa-ras oncogenes enhances the trans-repressor function of the Elk-1 transcription factor]. | Mol. Biol. (Mosk.) | pmid:12391846 | |
Vester BM et al. | Influence of feeding raw or extruded feline diets on nutrient digestibility and nitrogen metabolism of African wildcats (Felis lybica). | Zoo Biol. | pmid:20095004 | |
Jolly RA et al. | Microvesicular steatosis induced by a short chain fatty acid: effects on mitochondrial function and correlation with gene expression. | Toxicol Pathol | pmid:15503661 | |
Kim J et al. | Sodium butyrate regulates androgen receptor expression and cell cycle arrest in human prostate cancer cells. | Anticancer Res. | pmid:17970072 | |
Becker N et al. | Human intestinal microbiota: characterization of a simplified and stable gnotobiotic rat model. | Gut Microbes | pmid:21637015 | |
Cai L et al. | Evaluation of zeolite for control of odorants emissions from simulated poultry manure storage. | J. Environ. Qual. | pmid:17215226 | |
Gruchlik A et al. | EFFECTS OF 300 mT STATIC MAGNETIC FIELD ON IL-8 SECRETION IN NORMAL HUMAN COLON MYOFIBROBLASTS. | Acta Pol Pharm | pmid:26647628 | |
Varel VH et al. | Manure odor potential and Escherichia coli concentrations in manure slurries of feedlot steers fed 40% corn wet distillers grains. | J. Environ. Qual. | pmid:20830936 | |
Durdux M et al. | Fluorescence-based assessment of LRP activity: a comparative study. | Anticancer Res. | pmid:15161018 | |
Jung JW et al. | Augmentation of sodium butyrate-induced apoptosis by p38 MAP kinase inhibition in rat liver epithelial cells. | Antioxid. Redox Signal. | pmid:16356138 | |
pmid:16166714 | ||||
Vester BM et al. | Evaluation of nutrient digestibility and fecal characteristics of exotic felids fed horse- or beef-based diets: use of the domestic cat as a model for exotic felids. | Zoo Biol. | pmid:19830746 | |
Lea MA et al. | Induction of differentiation of colon cancer cells by combined inhibition of kinases and histone deacetylase. | Anticancer Res. | pmid:17465197 | |
Kien CL et al. | Lactulose feeding lowers cecal densities of clostridia in piglets. | JPEN J Parenter Enteral Nutr | pmid:17463144 | |
Liamleam W and Annachhatre AP | Electron donors for biological sulfate reduction. | Biotechnol. Adv. | pmid:17572039 | |
Rahman M et al. | The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPAR-gamma and SIRT-1 expression on a calorie restricted diet. | Oxid Med Cell Longev | pmid:20716918 | |
Sung YH et al. | Influence of down-regulation of caspase-3 by siRNAs on sodium-butyrate-induced apoptotic cell death of Chinese hamster ovary cells producing thrombopoietin. | Metab. Eng. | pmid:16169764 | |
Mackie RI et al. | Biochemical and microbiological evidence for fermentative digestion in free-living land iguanas (Conolophus pallidus) and marine iguanas (Amblyrhynchus cristatus) on the Galápagos archipelago. | Physiol. Biochem. Zool. | pmid:15057723 | |
Drozdowski LA et al. | Short-chain fatty acids and total parenteral nutrition affect intestinal gene expression. | JPEN J Parenter Enteral Nutr | pmid:12005453 | |
Tekucheva DN et al. | Immobilized purple bacteria for light-driven H2 production from starch and potato fermentation effluents. | Biotechnol. Prog. | pmid:21751433 | |
Loughrin JH et al. | Evaluation of second-generation multistage wastewater treatment system for the removal of malodors from liquid swine waste. | J. Environ. Qual. | pmid:19549951 | |
Wei ZL et al. | Enhancement of sodium butyrate-induced cell death by hyperthermia in HCT 116 human colorectal cancer cells. | Anticancer Res. | pmid:18630528 | |
Oh HK et al. | Effect of N-Acetylcystein on butyrate-treated Chinese hamster ovary cells to improve the production of recombinant human interferon-beta-1a. | Biotechnol. Prog. | pmid:16080696 | |
Orchel A et al. | Quantification of p21 gene expression in Caco-2 cells treated with sodium butyrate using real-time reverse transcription-PCR (RT-PCR) assay. | Acta Pol Pharm | pmid:13678314 | |
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Rossi DL et al. | A new mammalian host cell with enhanced survival enables completely serum-free development of high-level protein production cell lines. | Biotechnol. Prog. | pmid:21473000 | |
Han L et al. | Sodium butyrate activates erythroid-specific 5-aminolevulinate synthase gene through Sp1 elements at its promoter. | Blood Cells Mol. Dis. | pmid:18555711 | |
Cai G et al. | Metabolic flux network and analysis of fermentative hydrogen production. | Biotechnol. Adv. | pmid:21362466 | |
Gassull MA et al. | Macronutrients and bioactive molecules: is there a specific role in the management of inflammatory bowel disease? | JPEN J Parenter Enteral Nutr | pmid:15980281 | |
Taylor AJ and Beck CW | Histone deacetylases are required for amphibian tail and limb regeneration but not development. | Mech. Dev. | pmid:22947425 | |
Ghosh SK et al. | Short, discontinuous exposure to butyrate effectively sensitizes latently EBV-infected lymphoma cells to nucleoside analogue antiviral agents. | Blood Cells Mol. Dis. | pmid:17161633 | |
Fang HH et al. | Effects of Mo(VI) on phototrophic hydrogen production by Rhodobacter sphaeroides. | Environ Technol | pmid:21970170 | |
Zhang S et al. | Influence of pulsed electric field treatments on the volatile compounds of milk in comparison with pasteurized processing. | J. Food Sci. | pmid:21535640 | |
Wang Q et al. | Characterization of monocarboxylate transport in human kidney HK-2 cells. | Mol. Pharm. | pmid:17140255 | |
Lim SJ et al. | Effect of butyrate on the heregulin/ErbB-mediated proliferation of human colorectal cancer cells. | Mol Med Rep | pmid:21475856 | |
Bayés M and Rabasseda X | Gateways to clinical trials. | Methods Find Exp Clin Pharmacol | pmid:18389098 | |
Liu L et al. | Butyrate interferes with the differentiation and function of human monocyte-derived dendritic cells. | Cell. Immunol. | pmid:22698927 | |
Joachimiak R et al. | Influence of sodium butyrate on hepatocellular carcinoma (hepG2) and glioblastoma (C6) cell lines in vitro. | Acta Pol Pharm | pmid:18323252 | |
Fathallah H et al. | Differences in response to fetal hemoglobin induction therapy in beta-thalassemia and sickle cell disease. | Blood Cells Mol. Dis. | pmid:19346141 | |
Grebenová D et al. | The proteomic study of sodium butyrate antiproliferative/cytodifferentiation effects on K562 cells. | Blood Cells Mol. Dis. | pmid:16978890 | |
Sanduja S et al. | The roles of TTP and BRF proteins in regulated mRNA decay. | Wiley Interdiscip Rev RNA | pmid:21278925 | |
Bartholome AL et al. | Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets. | JPEN J Parenter Enteral Nutr | pmid:15291402 | |
pmid:11071567 | ||||
Bijaya G et al. | Synthesis and evaluation of esmolol prodrugs for transdermal delivery. | Drug Deliv | pmid:20553111 |