butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Acidosis D000138 13 associated lipids
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Alzheimer Disease D000544 76 associated lipids
Anaplasia D000708 1 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Angina Pectoris D000787 27 associated lipids
Aphakia, Postcataract D001036 1 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Astigmatism D001251 1 associated lipids
Ataxia Telangiectasia D001260 6 associated lipids
Sarcoma, Avian D001357 2 associated lipids
Body Weight D001835 333 associated lipids
Brain Diseases D001927 27 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Burns D002056 34 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Cattle Diseases D002418 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Colitis D003092 69 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Colorectal Neoplasms, Hereditary Nonpolyposis D003123 2 associated lipids
Constipation D003248 8 associated lipids
Corneal Diseases D003316 13 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Dental Leakage D003763 5 associated lipids
Dentin, Secondary D003809 2 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Diarrhea D003967 32 associated lipids
Disease Models, Animal D004195 4 associated lipids
Diverticulitis D004238 1 associated lipids
Diverticulitis, Colonic D004239 1 associated lipids
Dysentery D004403 4 associated lipids
Edema D004487 152 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Facial Injuries D005151 1 associated lipids
Fatty Liver D005234 48 associated lipids
Fragile X Syndrome D005600 5 associated lipids
Glioma D005910 112 associated lipids
Glycogen Storage Disease Type II D006009 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Hemolysis D006461 131 associated lipids
Hemorrhoids D006484 2 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Herpesviridae Infections D006566 4 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Hyperkinesis D006948 11 associated lipids
Hypothyroidism D007037 32 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Insulinoma D007340 28 associated lipids
Intestinal Neoplasms D007414 2 associated lipids
Ketosis D007662 13 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Laryngeal Neoplasms D007822 7 associated lipids
Leukemia D007938 74 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Leukemia, Megakaryoblastic, Acute D007947 7 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lymphatic Metastasis D008207 10 associated lipids
Lymphoma D008223 18 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Marek Disease D008380 4 associated lipids
Medulloblastoma D008527 22 associated lipids
Melanoma D008545 69 associated lipids
Myoepithelioma D009208 1 associated lipids
Nasopharyngeal Neoplasms D009303 4 associated lipids
Neoplastic Cells, Circulating D009360 5 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Nerve Degeneration D009410 53 associated lipids
Nervous System Diseases D009422 37 associated lipids
Neuroblastoma D009447 66 associated lipids
Nevus D009506 2 associated lipids
Nose Neoplasms D009669 3 associated lipids
Occupational Diseases D009784 42 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Periodontal Diseases D010510 15 associated lipids
Periodontitis D010518 22 associated lipids
Peritonitis D010538 38 associated lipids
Phenylketonurias D010661 7 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Poultry Diseases D011201 21 associated lipids
Pregnancy in Diabetics D011254 3 associated lipids
Proctitis D011349 1 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

Download all related citations
Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Antoni BA et al. NF-kappa B-dependent and -independent pathways of HIV activation in a chronically infected T cell line. 1994 Virology pmid:7913275
Ho SB et al. Stable differentiation of a human colon adenocarcinoma cell line by sodium butyrate is associated with multidrug resistance. 1994 J. Cell. Physiol. pmid:7913708
Papazafiri P et al. Expression of muscle calsequestrin in epithelial HeLa cells: distribution and functional role. 1994 Biochim. Biophys. Acta pmid:7918667
Tang MJ and Tannen RL Metabolic substrates alter attachment and differentiated functions of proximal tubule cell culture. 1994 J. Am. Soc. Nephrol. pmid:7919143
Katsarov V et al. Effect of the butyric short-chain fatty acid on the intracranial pressure and EEG of rabbits. 1993 Folia Med (Plovdiv) pmid:7927056
Schroy PC et al. Growth and intestinal differentiation are independently regulated in HT29 colon cancer cells. 1994 J. Cell. Physiol. pmid:7929596
Wu QH et al. Replication of human cytomegalovirus in cells deficient in beta 2-microglobulin gene expression. 1994 J. Gen. Virol. pmid:7931162
Swarovsky B et al. Sodium butyrate induces neuroendocrine cytodifferentiation in the insulinoma cell line RINm5F. 1994 Pancreas pmid:7937695
Pomponi MG and Neri G Butyrate and acetyl-carnitine inhibit the cytogenetic expression of the fragile X in vitro. 1994 Am. J. Med. Genet. pmid:7943015
Bode BP and Souba WW Modulation of cellular proliferation alters glutamine transport and metabolism in human hepatoma cells. 1994 Ann. Surg. pmid:7944654
Critchfield JW et al. Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-glycoprotein as a putative mechanism. 1994 Biochem. Pharmacol. pmid:7945444
Gupta S et al. Butyrate synchronization of hepatocytes: modulation of cycling and cell cycle regulated gene expression. 1994 Growth Factors pmid:7946406
Safaya S et al. Augmentation of gamma-globin gene promoter activity by carboxylic acids and components of the human beta-globin locus control region. 1994 Blood pmid:7949149
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Matsunaga N et al. Inhibitory effect of volatile fatty acids on GRF-induced GH secretion in sheep. 1993 Endocr. J. pmid:7951518
Ohannesian DW et al. Concomitant increases in galectin-1 and its glycoconjugate ligands (carcinoembryonic antigen, lamp-1, and lamp-2) in cultured human colon carcinoma cells by sodium butyrate. 1994 Cancer Res. pmid:7954433
Schaffer JE and Lodish HF Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein. 1994 Cell pmid:7954810
Tang MJ et al. Expression and regulation of Na, K-ATPase in primary culture of proximal tubule cells. 1994 Chin J Physiol pmid:7956509
Almouzni G et al. Histone acetylation influences both gene expression and development of Xenopus laevis. 1994 Dev. Biol. pmid:7958429
Perrin P et al. An interleukin 2/sodium butyrate combination as immunotherapy for rat colon cancer peritoneal carcinomatosis. 1994 Gastroenterology pmid:7958681
Chang AE Perspectives on interleukin-2 immunotherapy for colon cancer. 1994 Gastroenterology pmid:7958708
Coleman WB et al. Development of dexamethasone-inducible tyrosine aminotransferase activity in WB-F344 rat liver epithelial stemlike cells cultured in the presence of sodium butyrate. 1994 J. Cell. Physiol. pmid:7962128
Sun SH et al. Effects of sodium butyrate on the transfer of arachidonic acid to phosphatidylcholine in a clonal oligodendrocyte cell line (CB-II). 1994 Lipids pmid:7968267
Fanti L et al. Carnitine suppression of position-effect variegation in Drosophila melanogaster. 1994 Mol. Gen. Genet. pmid:7969027
Bartram HP et al. Antagonistic effects of deoxycholic acid and butyrate on epithelial cell proliferation in the proximal and distal human colon. 1994 Z Gastroenterol pmid:7975774
Mannon PJ et al. Characterization of a Y1-preferring NPY/PYY receptor in HT-29 cells. 1994 Am. J. Physiol. pmid:7977753
Mullany P et al. Genes encoding homologues of three consecutive enzymes in the butyrate/butanol-producing pathway of Clostridium acetobutylicum are clustered on the Clostridium difficile chromosome. 1994 FEMS Microbiol. Lett. pmid:8001771
Ebert PS and Salcman M Differentiation therapy is potentiated by chemotherapy and hyperthermia in human and canine brain tumor cells in vitro. 1994 Neurosurgery pmid:8008163
Sadaie MR and Hager GL Induction of developmentally programmed cell death and activation of HIV by sodium butyrate. 1994 Virology pmid:8009866
Walter KA et al. Studies of recombinant Clostridium acetobutylicum with increased dosages of butyrate formation genes. 1994 Ann. N. Y. Acad. Sci. pmid:8010698
Fariss MW et al. The selective antiproliferative effects of alpha-tocopheryl hemisuccinate and cholesteryl hemisuccinate on murine leukemia cells result from the action of the intact compounds. 1994 Cancer Res. pmid:8012947
Chen ZX and Breitman TR Tributyrin: a prodrug of butyric acid for potential clinical application in differentiation therapy. 1994 Cancer Res. pmid:8012972
Rydzyński K and Dalen H Effect of sodium butyrate treatment on the granule morphology, histamine level and elemental content of the bone marrow-derived mast cell. 1994 Folia Histochem. Cytobiol. pmid:8026597
Sandvig K et al. Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP. 1994 J. Cell Biol. pmid:8027186
Waagen V et al. Homochiral glycerol derivatives by lipase-catalysed racemate resolution. 1994 Protein Eng. pmid:8029217
Yamaguchi Y et al. Functional characterization of the promoter for the gene encoding human eosinophil peroxidase. 1994 J. Biol. Chem. pmid:8034708
Shadan FF et al. n-Butyrate, a cell cycle blocker, inhibits the replication of polyomaviruses and papillomaviruses but not that of adenoviruses and herpesviruses. 1994 J. Virol. pmid:8035479
Frankel W et al. Butyrate increases colonocyte protein synthesis in ulcerative colitis. 1994 J. Surg. Res. pmid:8041140
Peterec SM et al. Butyrate modulates surfactant protein mRNA in fetal rat lung by altering mRNA transcription and stability. 1994 Am. J. Physiol. pmid:8048547
Kaptein A et al. Butyrate stimulates the secretion of apolipoprotein B-100-containing lipoproteins from HepG2 cells by inhibiting the intracellular degradation. 1994 Biochim. Biophys. Acta pmid:8049249
Wadee AA et al. HLA expression in hepatocellular carcinoma cell lines. 1994 Clin. Exp. Immunol. pmid:8050184
Chen H et al. Characterization of two promoters of a rat pregnancy-specific glycoprotein gene. 1994 Biochemistry pmid:8068638
Austin C and Wray S A quantitative study of the relation between intracellular pH and force in rat mesenteric vascular smooth muscle. 1994 Pflugers Arch. pmid:8072846
Schreck R et al. Retinoids stimulate type I iodothyronine 5'-deiodinase activity in human follicular thyroid carcinoma cell lines. 1994 J. Clin. Endocrinol. Metab. pmid:8077363
Illg DJ et al. Effects of extruded soybeans and forage source on fermentation by rumen microorganisms in continuous culture. 1994 J. Dairy Sci. pmid:8083419
VanderMeulen DL et al. The identification of glioblastoma-associated, fucose-containing glycoproteins induced by retinoic acid. 1994 Feb-Apr Mol. Chem. Neuropathol. pmid:8086041
Oster T et al. Induction of recombinant human gamma-glutamyl transferase by sodium butyrate in transfected V79 and CHO Chinese hamster cells. 1993 Biochem. Biophys. Res. Commun. pmid:8099285
Reeder JA et al. Sodium butyrate differentially modulates plasminogen activator inhibitor type-1, urokinase plasminogen activator, and its receptor in a human colon carcinoma cell. 1993 Teratog., Carcinog. Mutagen. pmid:8102211
Frommel TO et al. Variable effects of sodium butyrate on the expression and function of the MDR1 (P-glycoprotein) gene in colon carcinoma cell lines. 1993 Int. J. Cancer pmid:8103760
Horvath PJ et al. Differential effect of butyrate on lipids of human colon cancer cells. 1993 Nutr Cancer pmid:8108277