butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Acidosis D000138 13 associated lipids
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Alzheimer Disease D000544 76 associated lipids
Anaplasia D000708 1 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Angina Pectoris D000787 27 associated lipids
Aphakia, Postcataract D001036 1 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Astigmatism D001251 1 associated lipids
Ataxia Telangiectasia D001260 6 associated lipids
Sarcoma, Avian D001357 2 associated lipids
Body Weight D001835 333 associated lipids
Brain Diseases D001927 27 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Burns D002056 34 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Cattle Diseases D002418 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Colitis D003092 69 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Colorectal Neoplasms, Hereditary Nonpolyposis D003123 2 associated lipids
Constipation D003248 8 associated lipids
Corneal Diseases D003316 13 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Dental Leakage D003763 5 associated lipids
Dentin, Secondary D003809 2 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Diarrhea D003967 32 associated lipids
Disease Models, Animal D004195 4 associated lipids
Diverticulitis D004238 1 associated lipids
Diverticulitis, Colonic D004239 1 associated lipids
Dysentery D004403 4 associated lipids
Edema D004487 152 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Facial Injuries D005151 1 associated lipids
Fatty Liver D005234 48 associated lipids
Fragile X Syndrome D005600 5 associated lipids
Glioma D005910 112 associated lipids
Glycogen Storage Disease Type II D006009 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Hemolysis D006461 131 associated lipids
Hemorrhoids D006484 2 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Herpesviridae Infections D006566 4 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Hyperkinesis D006948 11 associated lipids
Hypothyroidism D007037 32 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Insulinoma D007340 28 associated lipids
Intestinal Neoplasms D007414 2 associated lipids
Ketosis D007662 13 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Laryngeal Neoplasms D007822 7 associated lipids
Leukemia D007938 74 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Leukemia, Megakaryoblastic, Acute D007947 7 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lymphatic Metastasis D008207 10 associated lipids
Lymphoma D008223 18 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Marek Disease D008380 4 associated lipids
Medulloblastoma D008527 22 associated lipids
Melanoma D008545 69 associated lipids
Myoepithelioma D009208 1 associated lipids
Nasopharyngeal Neoplasms D009303 4 associated lipids
Neoplastic Cells, Circulating D009360 5 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Nerve Degeneration D009410 53 associated lipids
Nervous System Diseases D009422 37 associated lipids
Neuroblastoma D009447 66 associated lipids
Nevus D009506 2 associated lipids
Nose Neoplasms D009669 3 associated lipids
Occupational Diseases D009784 42 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Periodontal Diseases D010510 15 associated lipids
Periodontitis D010518 22 associated lipids
Peritonitis D010538 38 associated lipids
Phenylketonurias D010661 7 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Poultry Diseases D011201 21 associated lipids
Pregnancy in Diabetics D011254 3 associated lipids
Proctitis D011349 1 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

Download all related citations
Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Hodin RA et al. Cellular growth state differentially regulates enterocyte gene expression in butyrate-treated HT-29 cells. 1996 Cell Growth Differ. pmid:8732674
Diener M et al. Neuronally mediated anion secretion induced by short-chain fatty acids in the rat distal small intestine. 1996 Acta Physiol. Scand. pmid:8735652
Cheng G et al. [Isolation and reassociation of acetogen and methanogen in a syntrophobic coculture degrading butyrate anaerobically]. 1995 Wei Sheng Wu Xue Bao pmid:8745550
Velázquez OC et al. Butyrate inhibits seeding and growth of colorectal metastases to the liver in mice. 1996 Surgery pmid:8751616
Ogryzko VV et al. Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent. 1996 Mol. Cell. Biol. pmid:8756678
Acheson DW et al. Translocation of Shiga toxin across polarized intestinal cells in tissue culture. 1996 Infect. Immun. pmid:8757867
Goto I et al. Enhancement of sensitivity of human lung adenocarcinoma cells to growth-inhibitory activity of interferon alpha by differentiation-inducing agents. 1996 Br. J. Cancer pmid:8761368
Ghosh NK and Cox RP Induction of human follicle-stimulating hormone in HeLa cells by sodium butyrate. 1977 Nature pmid:876359
Dagher PC et al. Dissociation of colonic apical Na/H exchange activity from bulk cytoplasmic pH. 1996 Am. J. Physiol. pmid:8764164
Taggart MJ et al. Stimulus-dependent modulation of smooth muscle intracellular calcium and force by altered intracellular pH. 1996 Pflugers Arch. pmid:8772130
Feng P et al. Sodium butyrate is a potent modulator of smooth muscle cell proliferation and gene expression. 1996 Cell Prolif. pmid:8782486
McBain JA et al. Phorbol ester augments butyrate-induced apoptosis of colon cancer cells. 1996 Int. J. Cancer pmid:8782664
Rottleb C et al. Structure-activity relationship of 17 structural analogues of n-butyric acid upon c-myc expression. 1996 Int. J. Cancer pmid:8782665
Aaronson PI et al. Mechanism of butyrate-induced vasorelaxation of rat mesenteric resistance artery. 1996 Br. J. Pharmacol. pmid:8789392
Miettinen H and Huhtanen P Effects of the ratio of ruminal propionate to butyrate on milk yield and blood metabolites in dairy cows. 1996 J. Dairy Sci. pmid:8792285
Keane MM et al. The protein tyrosine phosphatase DEP-1 is induced during differentiation and inhibits growth of breast cancer cells. 1996 Cancer Res. pmid:8797598
Kopf MA et al. Key role of alkanoic acids on the spectral properties, activity, and active-site stability of iron-containing nitrile hydratase from Brevibacterium R312. 1996 Eur. J. Biochem. pmid:8797859
Welters CF et al. Supplementation of enteral nutrition with butyrate leads to increased portal efflux of amino acids in growing pigs with short bowel syndrome. 1996 J. Pediatr. Surg. pmid:8801305
Chireux M et al. Histone hyperacetylating agents stimulate promoter activity of human choline acetyltransferase gene in transfection experiment. 1996 Brain Res. Mol. Brain Res. pmid:8804715
Wasserman LM et al. cAMP effects on myogenic gene expression in rhabdomyosarcoma cells. 1996 Exp. Cell Res. pmid:8806451
Lindner H et al. Separation of acetylated core histones by hydrophilic-interaction liquid chromatography. 1996 J Chromatogr A pmid:8817877
Kendall PE and McLeay LM Excitatory effects of volatile fatty acids on the in vitro motility of the rumen of sheep. 1996 Res. Vet. Sci. pmid:8819185
Horiuchi A and Felder RA High-level expression of rat D1A dopamine receptor cDNA in mouse fibroblast LTK- cells by n-butyrate. 1996 Clin. Exp. Pharmacol. Physiol. pmid:8819644
Peldszus S et al. Determination of short-chain aliphatic, oxo- and hydroxy-acids in drinking water at low microgram per liter concentrations. 1996 J Chromatogr A pmid:8819819
Fukamauchi F et al. Differential effects of butyrate and dibutyryl cAMP on mRNA levels of muscarinic acetylcholine receptor subtypes expressed in neurohybrid cell lines. 1996 Neurosci. Lett. pmid:8823760
Vaziri C et al. Expression of the aryl hydrocarbon receptor is regulated by serum and mitogenic growth factors in murine 3T3 fibroblasts. 1996 J. Biol. Chem. pmid:8824226
Yamamoto I et al. Histone hyperacetylation plays a role in augmentation of IL-4-induced IgE production in LPS-stimulated murine B-lymphocytes by sodium butyrate. 1996 J. Biochem. pmid:8827437
Recht LD et al. Immunotoxin sensitivity of Chinese hamster ovary cells expressing human transferrin receptors with differing internalization rates. 1996 Cancer Immunol. Immunother. pmid:8830739
Mandal M and Kumar R Bcl-2 expression regulates sodium butyrate-induced apoptosis in human MCF-7 breast cancer cells. 1996 Cell Growth Differ. pmid:8838861
Whitelaw E and Williamson DH Effects of lactation of ketogenesis from oleate or butyrate in rat hepatocytes. 1977 Biochem. J. pmid:883950
Harig JM et al. Transport of n-butyrate into human colonic luminal membrane vesicles. 1996 Am. J. Physiol. pmid:8843764
Tiedge M and Lenzen S Effects of sodium butyrate on glucose transporter and glucose-phosphorylating enzyme gene expression in RINm5F insulinoma cells. 1996 J. Mol. Endocrinol. pmid:8863183
Velázquez OC et al. In vivo crypt surface hyperproliferation is decreased by butyrate and increased by deoxycholate in normal rat colon: associated in vivo effects on c-Fos and c-Jun expression. 1996 Jul-Aug JPEN J Parenter Enteral Nutr pmid:8865104
Egawa N et al. Differentiation of pancreatic carcinoma induced by retinoic acid or sodium butyrate: a morphological and molecular analysis of four cell lines. 1996 Virchows Arch. pmid:8865855
Uthayakumar S and Granger BL Cell surface accumulation of overexpressed hamster lysosomal membrane glycoproteins. 1995 Cell. Mol. Biol. Res. pmid:8867788
Ohbo M et al. Effects of saturated fatty acids on amylase release from exocrine pancreatic segments of sheep, rats, hamsters, field voles and mice. 1996 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. pmid:8870261
Sun R et al. Polyadenylylated nuclear RNA encoded by Kaposi sarcoma-associated herpesvirus. 1996 Proc. Natl. Acad. Sci. U.S.A. pmid:8876232
Moulding DA et al. Modulation of neutrophil apoptosis by pharmacological agents. 1996 Biochem. Soc. Trans. pmid:8879036
Nosbush BB et al. Effect of concentrate source and amount in diets on plasma hormone concentrations of prepubertal heifers. 1996 J. Dairy Sci. pmid:8880464
Roediger WE et al. Methionine derivatives diminish sulphide damage to colonocytes--implications for ulcerative colitis. 1996 Gut pmid:8881814
Nakai T et al. 1H-magnetic resonance spectroscopic observation of cultured malignant cells pharmacologically induced to different phenotypes. 1996 Acad Radiol pmid:8883515
Rogers KM and Barnsley EA The metabolism of S-carboxyalkylcysteines in man. 1977 Xenobiotica pmid:888445
Sandvig K et al. Importance of glycolipid synthesis for butyric acid-induced sensitization to shiga toxin and intracellular sorting of toxin in A431 cells. 1996 Mol. Biol. Cell pmid:8885234
Seki J et al. Dimethyl sulfoxide and related polar compounds enhance infection of human T cells with HIV-1 in vitro. 1996 Biochem. Biophys. Res. Commun. pmid:8886001
Basson MD et al. Regulation of human colonic cell line proliferation and phenotype by sodium butyrate. 1996 Dig. Dis. Sci. pmid:8888712
Siavoshian S et al. Butyrate enhances major histocompatibility complex class I, HLA-DR and ICAM-1 antigen expression on differentiated human intestinal epithelial cells. 1996 Eur. J. Clin. Invest. pmid:8889444
Thomas GL et al. Enhanced apoptosis in transformed human lung fibroblasts after exposure to sodium butyrate. 1996 In Vitro Cell. Dev. Biol. Anim. pmid:8889605
Treem WR et al. Fecal short-chain fatty acids in patients with diarrhea-predominant irritable bowel syndrome: in vitro studies of carbohydrate fermentation. 1996 J. Pediatr. Gastroenterol. Nutr. pmid:8890079
Frazier DP et al. The herpes simplex virus type 1 latency-associated transcript promoter is activated through Ras and Raf by nerve growth factor and sodium butyrate in PC12 cells. 1996 J. Virol. pmid:8892860
Frazier DP et al. Identification of cis-acting sequences in the promoter of the herpes simplex virus type 1 latency-associated transcripts required for activation by nerve growth factor and sodium butyrate in PC12 cells. 1996 J. Virol. pmid:8892861