butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
de Theije CG et al. | Altered gut microbiota and activity in a murine model of autism spectrum disorders. | 2014 | Brain Behav. Immun. | pmid:24333160 |
Zhong T et al. | Repression of contexual fear memory induced by isoflurane is accompanied by reduction in histone acetylation and rescued by sodium butyrate. | 2014 | Br J Anaesth | pmid:24838805 |
Machiels K et al. | A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis. | 2014 | Gut | pmid:24021287 |
Wang C et al. | A survey of fermentation products and bacterial communities in corn silage produced in a bunker silo in China. | 2014 | Anim. Sci. J. | pmid:23638801 |
Unno T et al. | Effect of dietary supplementation of (-)-epigallocatechin gallate on gut microbiota and biomarkers of colonic fermentation in rats. | 2014 | J. Nutr. Sci. Vitaminol. | pmid:25078378 |
Vidrine K et al. | Resistant starch from high amylose maize (HAM-RS2) and dietary butyrate reduce abdominal fat by a different apparent mechanism. | 2014 | Obesity (Silver Spring) | pmid:23630079 |
Wei Y et al. | Antidepressant-like effect of sodium butyrate is associated with an increase in TET1 and in 5-hydroxymethylation levels in the Bdnf gene. | 2014 | Int. J. Neuropsychopharmacol. | pmid:25618518 |
Liu J et al. | Sodium butyrate promotes the differentiation of rat bone marrow mesenchymal stem cells to smooth muscle cells through histone acetylation. | 2014 | PLoS ONE | pmid:25548915 |
Vicente F et al. | Subclinical ketosis on dairy cows in transition period in farms with contrasting butyric acid contents in silages. | 2014 | ScientificWorldJournal | pmid:25525616 |
Szymanowska-Powałowska D et al. | Biotechnological potential of Clostridium butyricum bacteria. | 2014 | Braz. J. Microbiol. | pmid:25477923 |
Brocato J et al. | Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression. | 2014 | J. Biol. Chem. | pmid:25266719 |
Kondo Y et al. | Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells. | 2014 | PLoS ONE | pmid:25084468 |
Vargas JE et al. | Inhibition of HDAC increases the senescence induced by natural polyphenols in glioma cells. | 2014 | Biochem. Cell Biol. | pmid:25070040 |
Ozadali K et al. | Synthesis and antimycobacterial activities of some new thiazolylhydrazone derivatives. | 2014 | Bioorg. Med. Chem. Lett. | pmid:24631185 |
Shen H et al. | BMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progression. | 2014 | J. Cell. Mol. Med. | pmid:24571310 |
Karki P et al. | Yin Yang 1 is a repressor of glutamate transporter EAAT2, and it mediates manganese-induced decrease of EAAT2 expression in astrocytes. | 2014 | Mol. Cell. Biol. | pmid:24469401 |
Pérez-Carro R et al. | Functional analysis and in vitro correction of splicing FAH mutations causing tyrosinemia type I. | 2014 | Clin. Genet. | pmid:23895425 |
White MK et al. | Rad51 activates polyomavirus JC early transcription. | 2014 | PLoS ONE | pmid:25310191 |
Miltko R et al. | Can fungal zoospores be the source of energy for the rumen protozoa Eudiplodinium maggii? | 2014 | Anaerobe | pmid:24012688 |
Katzenmaier EM et al. | Impact of sodium butyrate on the network of adhesion/growth-regulatory galectins in human colon cancer in vitro. | 2014 | Anticancer Res. | pmid:25275038 |
Takuma K et al. | Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism. | 2014 | Pharmacol. Biochem. Behav. | pmid:25240644 |
Valvassori SS et al. | Sodium butyrate functions as an antidepressant and improves cognition with enhanced neurotrophic expression in models of maternal deprivation and chronic mild stress. | 2014 | Curr Neurovasc Res | pmid:25233278 |
Nankova BB et al. | Enteric bacterial metabolites propionic and butyric acid modulate gene expression, including CREB-dependent catecholaminergic neurotransmission, in PC12 cells--possible relevance to autism spectrum disorders. | 2014 | PLoS ONE | pmid:25170769 |
Bilgraer R et al. | A new approach combining LC-MS and multivariate statistical analysis for revealing changes in histone modification levels. | 2014 | Mol Biosyst | pmid:25167371 |
Xu G et al. | SAHA regulates histone acetylation, Butyrylation, and protein expression in neuroblastoma. | 2014 | J. Proteome Res. | pmid:25160476 |
Khan S and Jena G | Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-β1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats. | 2014 | Food Chem. Toxicol. | pmid:25158305 |
Khalil NA et al. | In vitro batch cultures of gut microbiota from healthy and ulcerative colitis (UC) subjects suggest that sulphate-reducing bacteria levels are raised in UC and by a protein-rich diet. | 2014 | Int J Food Sci Nutr | pmid:23941288 |
Moeinian M et al. | Beneficial effect of butyrate, Lactobacillus casei and L-carnitine combination in preference to each in experimental colitis. | 2014 | World J. Gastroenterol. | pmid:25152589 |
Chou AH et al. | Polyglutamine-expanded ataxin-3 impairs long-term depression in Purkinje neurons of SCA3 transgenic mouse by inhibiting HAT and impairing histone acetylation. | 2014 | Brain Res. | pmid:25139423 |
Reindl A et al. | Enumeration of clostridia in goat milk using an optimized membrane filtration technique. | 2014 | J. Dairy Sci. | pmid:25129496 |
Kanski R et al. | Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network. | 2014 | J. Cell. Sci. | pmid:25128567 |
Lee JM et al. | Direct hydrogenation of biomass-derived butyric acid to n-butanol over a ruthenium-tin bimetallic catalyst. | 2014 | ChemSusChem | pmid:25123894 |
Lopez CA et al. | Collateral damage: microbiota-derived metabolites and immune function in the antibiotic era. | 2014 | Cell Host Microbe | pmid:25121745 |
Grandner MA et al. | Sleep symptoms associated with intake of specific dietary nutrients. | 2014 | J Sleep Res | pmid:23992533 |
Cho HJ and Song MJ | A gammaherpesvirus establishes persistent infection in neuroblastoma cells. | 2014 | Mol. Cells | pmid:25092213 |
Li S et al. | High-grain diets suppress ruminal tissue abundance of angiopoietin-like protein 4 in cattle. | 2014 | J. Anim. Sci. | pmid:25085388 |
Peterson EC and Daugulis AJ | Demonstration of in situ product recovery of butyric acid via CO2 -facilitated pH swings and medium development in two-phase partitioning bioreactors. | 2014 | Biotechnol. Bioeng. | pmid:23996152 |
Shin J et al. | The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner. | 2014 | J. Biol. Chem. | pmid:25037223 |
Weber TE et al. | Effects of dietary humic and butyric acid on growth performance and response to lipopolysaccharide in young pigs. | 2014 | J. Anim. Sci. | pmid:25023805 |
Nakata S et al. | Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity. | 2014 | Int. J. Oncol. | pmid:25017791 |
Tiwari P and Gupta KP | Modulation of miR-203 and its regulators as a function of time during the development of 7, 12 dimethylbenz [a] anthracene induced mouse skin tumors in presence or absence of the antitumor agents. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24792773 |
Lin Y et al. | Use of sodium butyrate as an alternative to dietary fiber: effects on the embryonic development and anti-oxidative capacity of rats. | 2014 | PLoS ONE | pmid:24852604 |
Pasvolsky R et al. | Butyric acid released during milk lipolysis triggers biofilm formation of Bacillus species. | 2014 | Int. J. Food Microbiol. | pmid:24801271 |
Utsugi C et al. | Hard-diet feeding recovers neurogenesis in the subventricular zone and olfactory functions of mice impaired by soft-diet feeding. | 2014 | PLoS ONE | pmid:24817277 |
Maggio A et al. | Daily sodium butyrate enema for the prevention of radiation proctitis in prostate cancer patients undergoing radical radiation therapy: results of a multicenter randomized placebo-controlled dose-finding phase 2 study. | 2014 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:24803033 |
Ellis JT et al. | Microbial bioproducts from cheese whey through fermentation with wastewater sludge Clostridium isolates. | 2014 | Can. J. Microbiol. | pmid:24898684 |
Milbradt EL et al. | Control of Salmonella Enteritidis in turkeys using organic acids and competitive exclusion product. | 2014 | J. Appl. Microbiol. | pmid:24797347 |
Ochiai K and Kurita-Ochiai T | [Alternative effects of a metabolic by-product, butyric acid, produced by oral anaerobes]. | 2014 | Nippon Yakurigaku Zasshi | pmid:25109521 |
Wang J et al. | Comparative effects of sodium butyrate and flavors on feed intake of lactating sows and growth performance of piglets. | 2014 | Anim. Sci. J. | pmid:24773759 |
Liu W et al. | Effects of dietary microencapsulated sodium butyrate on growth, intestinal mucosal morphology, immune response and adhesive bacteria in juvenile common carp (Cyprinus carpio) pre-fed with or without oxidised oil. | 2014 | Br. J. Nutr. | pmid:24774835 |
Saini M et al. | Metabolic engineering of Escherichia coli for production of butyric acid. | 2014 | J. Agric. Food Chem. | pmid:24773075 |
Ladirat SE et al. | Exploring the effects of galacto-oligosaccharides on the gut microbiota of healthy adults receiving amoxicillin treatment. | 2014 | Br. J. Nutr. | pmid:24925303 |
Dareioti MA et al. | Effect of pH on the anaerobic acidogenesis of agroindustrial wastewaters for maximization of bio-hydrogen production: a lab-scale evaluation using batch tests. | 2014 | Bioresour. Technol. | pmid:24759638 |
Castellano JF et al. | Reassessing the effects of histone deacetylase inhibitors on hippocampal memory and cognitive aging. | 2014 | Hippocampus | pmid:24753063 |
Zhou X et al. | Comparison of the effects of high energy carbon heavy ion irradiation and Eucommia ulmoides Oliv. on biosynthesis butyric acid efficiency in Clostridium tyrobutyricum. | 2014 | Bioresour. Technol. | pmid:24704888 |
Jang YS et al. | Metabolic engineering of Clostridium acetobutylicum for butyric acid production with high butyric acid selectivity. | 2014 | Metab. Eng. | pmid:24704310 |
Syngiridis K et al. | Favouring butyrate production for a new generation biofuel by acidogenic glucose fermentation using cells immobilised on γ-alumina. | 2014 | Bioresour. Technol. | pmid:24690582 |
Sarkar A et al. | Hippocampal HDAC4 contributes to postnatal fluoxetine-evoked depression-like behavior. | 2014 | Neuropsychopharmacology | pmid:24663010 |
Csikó G et al. | Effects of dietary sodium butyrate on hepatic biotransformation and pharmacokinetics of erythromycin in chickens. | 2014 | J. Vet. Pharmacol. Ther. | pmid:24628435 |
Han A et al. | Possible additional antidepressant-like mechanism of sodium butyrate: targeting the hippocampus. | 2014 | Neuropharmacology | pmid:24607816 |
Park HG et al. | Repeated treatment with electroconvulsive seizures induces HDAC2 expression and down-regulation of NMDA receptor-related genes through histone deacetylation in the rat frontal cortex. | 2014 | Int. J. Neuropsychopharmacol. | pmid:24606669 |
Aguilar EC et al. | Butyrate impairs atherogenesis by reducing plaque inflammation and vulnerability and decreasing NFκB activation. | 2014 | Nutr Metab Cardiovasc Dis | pmid:24602606 |
Sabra W et al. | Improved n-butanol production by a non-acetone producing Clostridium pasteurianum DSMZ 525 in mixed substrate fermentation. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24584460 |
Blank M et al. | Basolateral amygdala activity is required for enhancement of memory consolidation produced by histone deacetylase inhibition in the hippocampus. | 2014 | Neurobiol Learn Mem | pmid:24583371 |
Possebom G et al. | Esterification of fatty acids by Penicillium crustosum lipase in a membrane reactor. | 2014 | J. Sci. Food Agric. | pmid:24578290 |
Zhu Y et al. | The role and interactions of cytosolic alkalization and hydrogen peroxide in ultraviolet B-induced stomatal closure in Arabidopsis. | 2014 | Plant Sci. | pmid:24388518 |
Zhang Z et al. | Sodium butyrate facilitates reprogramming by derepressing OCT4 transactivity at the promoter of embryonic stem cell-specific miR-302/367 cluster. | 2014 | Cell Reprogram | pmid:24568633 |
Kato R et al. | The synergistic effect of 1'-acetoxychavicol acetate and sodium butyrate on the death of human hepatocellular carcinoma cells. | 2014 | Chem. Biol. Interact. | pmid:24480522 |
Bolhari B et al. | Acid and microhardness of mineral trioxide aggregate and mineral trioxide aggregate-like materials. | 2014 | J Endod | pmid:24565666 |
Saldanha SN et al. | Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate. | 2014 | Exp. Cell Res. | pmid:24518414 |
Ai B et al. | Butyric acid fermentation of sodium hydroxide pretreated rice straw with undefined mixed culture. | 2014 | J. Microbiol. Biotechnol. | pmid:24561721 |
Cerisuelo A et al. | The impact of a specific blend of essential oil components and sodium butyrate in feed on growth performance and Salmonella counts in experimentally challenged broilers. | 2014 | Poult. Sci. | pmid:24604853 |
Hong JK et al. | Effect of sodium butyrate on the assembly, charge variants, and galactosylation of antibody produced in recombinant Chinese hamster ovary cells. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24557571 |
Ronzoni L et al. | Modulation of gamma globin genes expression by histone deacetylase inhibitors: an in vitro study. | 2014 | Br. J. Haematol. | pmid:24606390 |
Liu Y et al. | Sodium butyrate enhances the acidic isoform content of recombinant human erythropoietin produced by Chinese hamster ovary cells. | 2014 | Biotechnol. Lett. | pmid:24557070 |
Hu X et al. | Histone deacetylase inhibitor sodium butyrate promotes the osteogenic differentiation of rat adipose-derived stem cells. | 2014 | Dev. Growth Differ. | pmid:24494796 |
Xiao M et al. | Sodium butyrate induces apoptosis of human colon cancer cells by modulating ERK and sphingosine kinase 2. | 2014 | Biomed. Environ. Sci. | pmid:24709100 |
Hu WT et al. | Transient folate deprivation in combination with small-molecule compounds facilitates the generation of somatic cell-derived pluripotent stem cells in mice. | 2014 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:24710923 |
Yamamura T et al. | Sodium butyrate, a histone deacetylase inhibitor, regulates Lymphangiogenic factors in oral cancer cell line HSC-3. | 2014 | Anticancer Res. | pmid:24692699 |
Kumar P et al. | All-trans retinoic acid and sodium butyrate enhance natriuretic peptide receptor a gene transcription: role of histone modification. | 2014 | Mol. Pharmacol. | pmid:24714214 |
Dos Santos MP et al. | In vitro antitumor effect of sodium butyrate and zoledronic acid combined with traditional chemotherapeutic drugs: a paradigm of synergistic molecular targeting in the treatment of Ewing sarcoma. | 2014 | Oncol. Rep. | pmid:24316794 |
Núñez-Jaramillo L et al. | Sodium butyrate into the insular cortex during conditioned taste-aversion acquisition delays aversive taste memory extinction. | 2014 | Neuroreport | pmid:24323127 |
Lee SM et al. | Digital mRNA profiling of N-glycosylation gene expression in recombinant Chinese hamster ovary cells treated with sodium butyrate. | 2014 | J. Biotechnol. | pmid:24333461 |
Tariq M et al. | Synthesis, spectroscopic, X-ray crystal structure, biological and DNA interaction studies of organotin(IV) complexes of 2-(4-ethoxybenzylidene) butanoic acid. | 2014 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:24322756 |
Dostal A et al. | Iron supplementation promotes gut microbiota metabolic activity but not colitis markers in human gut microbiota-associated rats. | 2014 | Br. J. Nutr. | pmid:24555487 |
Gagliano H et al. | High doses of the histone deacetylase inhibitor sodium butyrate trigger a stress-like response. | 2014 | Neuropharmacology | pmid:24212060 |
Tailor D et al. | Sodium butyrate induces DRP1-mediated mitochondrial fusion and apoptosis in human colorectal cancer cells. | 2014 | Mitochondrion | pmid:24177748 |
Khan S and Jena GB | Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: study in juvenile diabetic rat. | 2014 | Chem. Biol. Interact. | pmid:24530320 |
Peterson AB et al. | Dose-dependent effects of wheel running on cocaine-seeking and prefrontal cortex Bdnf exon IV expression in rats. | 2014 | Psychopharmacology (Berl.) | pmid:24173624 |
Ferreira AC et al. | Histone deacetylase inhibitor prevents cell growth in Burkitt's lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101. | 2014 | Ann. Hematol. | pmid:24577510 |
Fang CL et al. | Effects of sodium butyrate on growth performance, haematological and immunological characteristics of weanling piglets. | 2014 | J Anim Physiol Anim Nutr (Berl) | pmid:24024579 |
Dengler F et al. | Bicarbonate-dependent transport of acetate and butyrate across the basolateral membrane of sheep rumen epithelium. | 2014 | Acta Physiol (Oxf) | pmid:23927569 |
Meehan CJ and Beiko RG | A phylogenomic view of ecological specialization in the Lachnospiraceae, a family of digestive tract-associated bacteria. | 2014 | Genome Biol Evol | pmid:24625961 |
Yan SF et al. | HDAC inhibitor sodium butyrate augments the MEF2C enhancement of Nampt expression under hypoxia. | 2014 | Curr. Pharm. Des. | pmid:23888946 |
Pan Y et al. | Potential usefulness of baculovirus-mediated sodium-iodide symporter reporter gene as non-invasively gene therapy monitoring in liver cancer cells: an in vitro evaluation. | 2014 | Technol. Cancer Res. Treat. | pmid:23919394 |
Drees J et al. | Butyrate stimulates the early process of the osteogenic differentiation but inhibits the biomineralization in dental follicle cells (DFCs). | 2014 | Odontology | pmid:23836050 |
Stertz L et al. | Histone deacetylase activity and brain-derived neurotrophic factor (BDNF) levels in a pharmacological model of mania. | 2014 Jan-Mar | Rev Bras Psiquiatr | pmid:24346357 |
Moran JK et al. | The Scent of Blood: A Driver of Human Behavior? | 2015 | PLoS ONE | pmid:26397374 |
Sun J et al. | Neuroprotective Effect of Sodium Butyrate against Cerebral Ischemia/Reperfusion Injury in Mice. | 2015 | Biomed Res Int | pmid:26064905 |
Kowalski ZM et al. | Effect of microencapsulated sodium butyrate in the close-up diet on performance of dairy cows in the early lactation period. | 2015 | J. Dairy Sci. | pmid:25726104 |