butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Aphakia, Postcataract D001036 1 associated lipids
Diverticulosis, Colonic D043963 1 associated lipids
Facial Injuries D005151 1 associated lipids
Gastrinoma D015408 1 associated lipids
Myoepithelioma D009208 1 associated lipids
Proctitis D011349 1 associated lipids
Salivary Gland Neoplasms D012468 1 associated lipids
Astigmatism D001251 1 associated lipids
Diverticulitis D004238 1 associated lipids
Anaplasia D000708 1 associated lipids
Trophoblastic Neoplasms D014328 1 associated lipids
Diverticulitis, Colonic D004239 1 associated lipids
Sarcoma, Avian D001357 2 associated lipids
Dentin, Secondary D003809 2 associated lipids
Colorectal Neoplasms, Hereditary Nonpolyposis D003123 2 associated lipids
Lymphoma, AIDS-Related D016483 2 associated lipids
Nevus D009506 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Urea Cycle Disorders, Inborn D056806 2 associated lipids
Glycogen Storage Disease Type II D006009 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Authors Title Published Journal PubMed Link
Van Lier JB et al. Effects of acetate, propionate, and butyrate on the thermophilic anaerobic degradation of propionate by methanogenic sludge and defined cultures. 1993 Appl. Environ. Microbiol. pmid:8476278
Lea MA et al. Butyramide and monobutyrin: growth inhibitory and differentiating agents. 1993 Jan-Feb Anticancer Res. pmid:8476205
Gill RK and Christakos S Identification of sequence elements in mouse calbindin-D28k gene that confer 1,25-dihydroxyvitamin D3- and butyrate-inducible responses. 1993 Proc. Natl. Acad. Sci. U.S.A. pmid:8464915
Iwai SA et al. Changes in Hox1.6, c-jun, and Oct-3 gene expressions are associated with teratocarcinoma F9 cell differentiation in three different ways of induction. 1993 Exp. Cell Res. pmid:8453995
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Saito H et al. Effect of butyric acid on induction of differentiation into eosinophil-like cells in human eosinophilic leukemia cells, EoL-1 cell line: possible role of granulocyte-macrophage colony-stimulating factor as an autocrine differentiating factor. 1993 Int. Arch. Allergy Immunol. pmid:8453311
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Herz F Divergent effects of butyrate on the alkaline phosphatases of SW-620 cells. 1993 Biochim. Biophys. Acta pmid:8422435
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Dohi T et al. Induction of the fundic mucosa-specific glycolipid with dimethylformamide in gastric-cancer cell lines. 1993 Int. J. Cancer pmid:8416198
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Wischmeyer P et al. Chronic pouchitis after ileal pouch-anal anastomosis: responses to butyrate and glutamine suppositories in a pilot study. 1993 Mayo Clin. Proc. pmid:8412364
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Gaudet SJ et al. Differential regulation of arylamine and arylalkylamine N-acetyltransferases in human retinoblastoma (Y-79) cells. 1993 Neurochem. Int. pmid:8382984
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Laughlin MA et al. Sodium butyrate treatment of cells latently infected with HIV-1 results in the expression of unspliced viral RNA. 1993 Virology pmid:8372431
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Wiekowski M et al. Requirements for promoter activity in mouse oocytes and embryos distinguish paternal pronuclei from maternal and zygotic nuclei. 1993 Dev. Biol. pmid:8365573
Calabresse C et al. Butyric acid and its monosaccharide ester induce apoptosis in the HL-60 cell line. 1993 Biochem. Biophys. Res. Commun. pmid:8363611
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Murray NR et al. Protein kinase C isotypes in human erythroleukemia (K562) cell proliferation and differentiation. Evidence that beta II protein kinase C is required for proliferation. 1993 J. Biol. Chem. pmid:8340409
Cremer JE et al. The influence of portocaval anastomosis on the metabolism of labelled octanoate, butyrate and leucine in rat brain. 1977 J. Neurochem. pmid:833594
Komatsu N et al. Establishment and characterization of an erythropoietin-dependent subline, UT-7/Epo, derived from human leukemia cell line, UT-7. 1993 Blood pmid:8329702
Souleimani A and Asselin C Regulation of c-myc expression by sodium butyrate in the colon carcinoma cell line Caco-2. 1993 FEBS Lett. pmid:8325387
Bartram HP et al. Proliferation of human colonic mucosa as an intermediate biomarker of carcinogenesis: effects of butyrate, deoxycholate, calcium, ammonia, and pH. 1993 Cancer Res. pmid:8324739
Chapman MA et al. Butyrate oxidation is impaired in the colonic mucosa of sufferers of quiescent ulcerative colitis. 1994 Gut pmid:8307454
Yabushita H and Sartorelli AC Effects of sodium butyrate, dimethylsulfoxide and dibutyryl cAMP on the poorly differentiated ovarian adenocarcinoma cell line AMOC-2. 1993 Oncol. Res. pmid:8305743
Steinhart AH et al. Treatment of refractory ulcerative proctosigmoiditis with butyrate enemas. 1994 Am. J. Gastroenterol. pmid:8304299
Fernandez-Mejia C and Davidson MB Effect of sodium butyrate on glucose transport and glucose-phosphorylating enzymes in RIN-m5F cells. 1993 Pancreas pmid:8302795
Dong QG et al. Isolation of a mitomycin-resistant human lung adenocarcinoma cell subline to investigate the modulation by sodium butyrate of cell growth and drug resistance. 1993 Anticancer Drugs pmid:8298162
Carraro S et al. [Influence of sodium butyrate intake on murine colonic carcinogenesis]. 1993 Medicina (B Aires) pmid:8295530
Iwami K and Moriyama T Effects of short chain fatty acid, sodium butyrate, on osteoblastic cells and osteoclastic cells. 1993 Int. J. Biochem. pmid:8288032
Roediger WE et al. Sulphide impairment of substrate oxidation in rat colonocytes: a biochemical basis for ulcerative colitis? 1993 Clin. Sci. pmid:8287651
Sperker B et al. The expression of human plasma cholesteryl-ester-transfer protein in HepG2 cells is induced by sodium butyrate. Quantification of low mRNA levels by polymerase chain reaction. 1993 Eur. J. Biochem. pmid:8281947
Hague A et al. Escape from negative regulation of growth by transforming growth factor beta and from the induction of apoptosis by the dietary agent sodium butyrate may be important in colorectal carcinogenesis. 1993 Cancer Metastasis Rev. pmid:8281610