butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Waalkes MP and Wilson MJ | Enhancement of cadmium-induced metallothionein synthesis in cultured TRL 1215 cells by butyric acid pretreatment. | 1986 | Toxicol. Lett. | pmid:3775811 |
Cheng ML et al. | A novel system for storage of sera frozen in small aliquots. | 1986 | J. Biochem. Biophys. Methods | pmid:3772018 |
Ortiz-Caro J et al. | Modulation of thyroid hormone nuclear receptors by short-chain fatty acids in glial C6 cells. Role of histone acetylation. | 1986 | J. Biol. Chem. | pmid:3771518 |
Ortiz-Caro J et al. | Identification and characterization of L-triiodothyronine receptors in cells of glial and neuronal origin. | 1986 | Endocrinology | pmid:3769867 |
Sherman MM et al. | Biosynthesis of lasalocid A. Metabolic interrelationships of carboxylic acid precursors and polyether antibiotics. | 1986 | J. Antibiot. | pmid:3759663 |
Schweitzer EJ et al. | Bile acid accumulation by rabbit esophageal mucosa. | 1986 | Dig. Dis. Sci. | pmid:3757726 |
Smith PJ | n-Butyrate alters chromatin accessibility to DNA repair enzymes. | 1986 | Carcinogenesis | pmid:3753905 |
Ollivier-Bousquet M and Demarne Y | [Effect of prolactin on milk lipid secretion in epithelial mammary cells of the lactating rabbit]. | 1986 | Reprod Nutr Dev | pmid:3749599 |
Franco G et al. | Serum bile acid concentrations as a liver function test in workers occupationally exposed to organic solvents. | 1986 | Int Arch Occup Environ Health | pmid:3744570 |
Jørgensen KE and Sheikh MI | Characteristics of uptake of short chain fatty acids by luminal membrane vesicles from rabbit kidney. | 1986 | Biochim. Biophys. Acta | pmid:3741867 |
Saroka JM and Combs GF | The lack of effect of a pyridoxine deficiency on the utilization of the hydroxyl analogue of methionine by the chick. | 1986 | Poult. Sci. | pmid:3737508 |
Freeman HJ | Effects of differing concentrations of sodium butyrate on 1,2-dimethylhydrazine-induced rat intestinal neoplasia. | 1986 | Gastroenterology | pmid:3732764 |
Wright PS et al. | Butyrate effects on normal and adapted hepatoma cells: morphological response and implications for vectoral cholesterol transport. | 1986 | Arch. Biochem. Biophys. | pmid:3729417 |
Tarloff JB and Brand PH | Active tetraethylammonium uptake across the basolateral membrane of rabbit proximal tubule. | 1986 | Am. J. Physiol. | pmid:3728682 |
Björkman C and Forslund K | Volatile fatty acids in adult and young ruminants: an evaluation of a gas chromatographic method. | 1986 | J. Dairy Sci. | pmid:3722541 |
Arundel CM et al. | Contrasting effects of the differentiating agent sodium butyrate on recovery processes after x-irradiation in heterogeneous human colon tumor cells. | 1986 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:3721937 |
Barnea ER et al. | Monoamine oxidase activity in the term human placenta. | 1986 | Am J Perinatol | pmid:3718643 |
Roediger WE et al. | Anion control of sodium absorption in the colon. | 1986 | Q J Exp Physiol | pmid:3714959 |
Ronot X et al. | G2 arrest, binucleation, and single-parameter DNA flow cytometric analysis. | 1986 | Cytometry | pmid:3709309 |
Mullenders LH et al. | Distribution of u.v.-induced repair events in higher-order chromatin loops in human and hamster fibroblasts. | 1986 | Carcinogenesis | pmid:3708760 |
Wawra E | Longterm effects of sodium butyrate on mouse fibroblasts: a model for differentiation? | 1986 | Cell. Mol. Biol. | pmid:3708657 |
Der Garabedian PA et al. | 4-Aminobutyrate:2-oxoglutarate aminotransferase from Candida. Purification and properties. | 1986 | Eur. J. Biochem. | pmid:3699025 |
Nakagawa Y and Perentes E | Determination by anti-bromodeoxyuridine monoclonal antibody of cells in S phase in the human Y79 retinoblastoma line maintained in an organ culture system: effects of butyric acid. | 1987 | Ophthalmic Res. | pmid:3696696 |
Polack A et al. | Truncation does not abrogate transcriptional downregulation of the c-myc gene by sodium butyrate in Burkitt's lymphoma cells. | 1987 | EMBO J. | pmid:3691477 |
Naguib FN et al. | Effects of N,N-dimethylformamide and sodium butyrate on enzymes of pyrimidine metabolism in cultured human tumor cells. | 1987 | Leuk. Res. | pmid:3682865 |
Cummings JH et al. | Short chain fatty acids in human large intestine, portal, hepatic and venous blood. | 1987 | Gut | pmid:3678950 |
Miller AA et al. | Clinical pharmacology of sodium butyrate in patients with acute leukemia. | 1987 | Eur J Cancer Clin Oncol | pmid:3678322 |
Kristev A et al. | The impact of butyric acid on the cardiovascular system. | 1987 | Cor Vasa | pmid:3677720 |
Fiehn NE | Biochemical characterization of nine oral small-sized spirochete strains containing one endoflagellum from each cell-end. | 1987 | Acta Pathol Microbiol Immunol Scand B | pmid:3673586 |
Paul CY et al. | Comparison of the pharmacokinetics of AMSA and AMSA-lactate in patients with acute nonlymphoblastic leukemia. | 1987 | Ther Drug Monit | pmid:3672568 |
Stephens GM and Dalton H | The effect of lipophilic weak acids on the segregational stability of TOL plasmids in Pseudomonas putida. | 1987 | J. Gen. Microbiol. | pmid:3668501 |
Gupta KP and Mehrotra NK | Effect of butyric acid on 12-O-tetradecanoylphorbol-13-acetate-(TPA) induced mouse skin ornithine decarboxylase (ODC). | 1987 | Carcinogenesis | pmid:3664957 |
Augenlicht LH et al. | Expression of cloned sequences in biopsies of human colonic tissue and in colonic carcinoma cells induced to differentiate in vitro. | 1987 | Cancer Res. | pmid:3664505 |
Scheppach WM et al. | Fecal short-chain fatty acid (SCFA) analysis by capillary gas-liquid chromatography. | 1987 | Am. J. Clin. Nutr. | pmid:3661480 |
Horning MG et al. | Analytical methods for the study of urinary thioether metabolites in the rat and guinea pig. | 1987 | J. Chromatogr. | pmid:3654858 |
Lampugnani MG et al. | Effects of dimethyl sulfoxide (DMSO) on microfilament organization, cellular adhesion, and growth of cultured mouse B16 melanoma cells. | 1987 | Exp. Cell Res. | pmid:3653263 |
Byrd JC et al. | Proenkephalin gene expression in the PC12 pheochromocytoma cell line: stimulation by sodium butyrate. | 1987 | Endocrinology | pmid:3653029 |
Chou JY and Takahashi S | Control of placental alkaline phosphatase gene expression in HeLa cells: induction of synthesis by prednisolone and sodium butyrate. | 1987 | Biochemistry | pmid:3651399 |
Grunicke H et al. | Alkylating antitumor agents reduce histone acetyl-transferase activity. | 1986 | Adv. Enzyme Regul. | pmid:3643697 |
Staecker JL et al. | Stimulation of DNA synthesis in primary cultures of adult rat hepatocytes by sodium butyrate. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3632683 |
Hansen HO and Knudsen J | Effect of exogenous long-chain fatty acids on individual fatty acid synthesis by dispersed ruminant mammary gland cells. | 1987 | J. Dairy Sci. | pmid:3624591 |
Riley TV | A note on hydrolysis of tributyrin by Branhamella and Neisseria. | 1987 | J. Appl. Bacteriol. | pmid:3624107 |
McNeil NI et al. | Mucosal surface pH of the large intestine of the rat and of normal and inflamed large intestine in man. | 1987 | Gut | pmid:3623217 |
Conway JG et al. | Role of fatty acyl coenzyme A oxidase in the efflux of oxidized glutathione from perfused livers of rats treated with the peroxisome proliferator nafenopin. | 1987 | Cancer Res. | pmid:3621175 |
Sakata T | Stimulatory effect of short-chain fatty acids on epithelial cell proliferation in the rat intestine: a possible explanation for trophic effects of fermentable fibre, gut microbes and luminal trophic factors. | 1987 | Br. J. Nutr. | pmid:3620440 |
Janati-Idrissi R et al. | [Selection of mutants of Clostridium acetobutylicum defective in production of acetone]. | 1987 May-Jun | Ann. Inst. Pasteur Microbiol. | pmid:3620201 |
Radcliffe BC et al. | Effect of luminal or circulating nitrite on colonic ion movement in the rat. | 1987 | Am. J. Physiol. | pmid:3618784 |
Andrey D | A simple gas chromatography method for the determination of ethylcarbamate in spirits. | 1987 | Z Lebensm Unters Forsch | pmid:3617935 |
Andrews GK and Adamson ED | Butyrate selectively activates the metallothionein gene in teratocarcinoma cells and induces hypersensitivity to metal induction. | 1987 | Nucleic Acids Res. | pmid:3601676 |
Ceccarelli P et al. | Resistance to thyroid hormone diagnosed by the reduced response of fibroblasts to the triiodothyronine-induced suppression of fibronectin synthesis. | 1987 | J. Clin. Endocrinol. Metab. | pmid:3597704 |
Su WJ et al. | Role of volatile fatty acids in colonization resistance to Clostridium difficile in gnotobiotic mice. | 1987 | Infect. Immun. | pmid:3596806 |
Fujiwara Y et al. | Heritable disorders of DNA repair: xeroderma pigmentosum and Fanconi's anemia. | 1987 | Curr. Probl. Dermatol. | pmid:3595188 |
Newsholme P et al. | Rates of utilization and fates of glucose, glutamine, pyruvate, fatty acids and ketone bodies by mouse macrophages. | 1987 | Biochem. J. | pmid:3593269 |
Harris MG et al. | Flexure and residual astigmatism with Paraperm O2 and Boston II lenses on toric corneas. | 1987 | Am J Optom Physiol Opt | pmid:3591898 |
Cohn PD et al. | Differences in nonspecific esterase from normal and leukemic monocytes. | 1987 | Blood | pmid:3580567 |
Wasicki P et al. | [Polarographic determination of patulin]. | 1986 | Pharmazie | pmid:3575386 |
el-Deriny SE et al. | Ultrastructural differentiation and CEA expression of butyrate-treated human pancreatic carcinoma cells. | 1987 | Pancreas | pmid:3575313 |
Amendt BA et al. | Short-chain acyl-coenzyme A dehydrogenase deficiency. Clinical and biochemical studies in two patients. | 1987 | J. Clin. Invest. | pmid:3571488 |
Harmon DL et al. | Influence of decoquinate on ruminal fermentation, diet digestibility and cattle performance. | 1987 | J. Anim. Sci. | pmid:3571027 |
Dvorak AM et al. | Beige mouse mast cells generated in vitro: ultrastructural analysis of maturation induced by sodium butyrate and of IgE-mediated, antigen-dependent degranulation. | 1987 | Int. Arch. Allergy Appl. Immunol. | pmid:3570497 |
Monahan-Earley RA et al. | Nonspecific esterase activity expressed in Weibel-Palade bodies of cloned guinea pig aortic endothelial cells. | 1987 | J. Histochem. Cytochem. | pmid:3559181 |
Mitsuhashi T et al. | n-Butyrate increases the level of thyroid hormone nuclear receptor in non-pituitary cultured cells. | 1987 | J. Biol. Chem. | pmid:3558403 |
Ortiz-Caro J et al. | Down-regulation of thyroid hormone nuclear receptor levels by L-triiodothyronine in cultured glial C6 cells. | 1987 | Mol. Cell. Endocrinol. | pmid:3556756 |
Philippe J et al. | Transcriptional regulation of genes encoding insulin, glucagon, and angiotensinogen by sodium butyrate in a rat islet cell line. | 1987 | Mol. Cell. Biol. | pmid:3550424 |
Nelson NF et al. | Modulation of secreted plasminogen activator activity of human renal carcinoma cells by dimethylsulfoxide, butyrate and retinoate. | 1987 | Cancer Lett. | pmid:3548947 |
Kakizoe H and Ninagawa T | [The development of enzyme immunoassay for prostaglandin F2 alpha]. | 1987 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:3546538 |
Nakanishi T and Hashimoto K | The differential reactivity of benign and malignant nevomelanocytic lesions with mouse monoclonal antibody TNKH1. | 1987 | Cancer | pmid:3545436 |
Merle-Beral H et al. | A T chronic lymphocytic leukemia with large granular lymphocytes. Phenotype and functions of leukemic cells under in vitro treatment by differentiation inducers. | 1987 | Cancer | pmid:3545432 |
Bianchi Scarrà GL et al. | Terminal erythroid differentiation in the K-562 cell line by 1-beta-D-arabinofuranosylcytosine: accompaniment by c-myc messenger RNA decrease. | 1986 | Cancer Res. | pmid:3536078 |
Neu HC | beta-Lactam antibiotics: structural relationships affecting in vitro activity and pharmacologic properties. | 1986 Jul-Aug | Rev. Infect. Dis. | pmid:3529320 |
Kyritsis AP et al. | Distribution of the regulatory subunit of type II cAMP-dependent protein kinase in Y-79 retinoblastoma cells. Effect of butyrate. | 1986 | Invest. Ophthalmol. Vis. Sci. | pmid:3528034 |
Said A et al. | [The effect of intravenous administration of butyrate, isobutyrate, isovalerate and capronate on the blood plasma levels in sheep of glucose, insulin, free fatty acids and total alpha-amino-nitrogen]. | 1986 | Arch Exp Veterinarmed | pmid:3524500 |
Said A et al. | [The effect of intravenous administration of butyrate, isobutyrate, isovalerate and capronate to calves, young cattle and cattle on the blood plasma levels of glucose, insulin, free fatty acids and total alpha-amino-nitrogen]. | 1986 | Arch Exp Veterinarmed | pmid:3524499 |
Fine DH and Mandel ID | Indicators of periodontal disease activity: an evaluation. | 1986 | J. Clin. Periodontol. | pmid:3522656 |
Bratusch-Marrain PR and DeFronzo RA | Failure of hyperketonemia to alter basal and insulin-mediated glucose metabolism in man. | 1986 | Horm. Metab. Res. | pmid:3516834 |
Brett JG et al. | Phenotypic and karyotypic transitions in the spontaneous transformation of a rat cell line. | 1986 | Tissue Cell | pmid:3515628 |
Alonso WR and Nelson DA | A novel yeast histone deacetylase: partial characterization and development of an activity assay. | 1986 | Biochim. Biophys. Acta | pmid:3513841 |
Addicks WJ et al. | Validation of a flow-through diffusion cell for use in transdermal research. | 1987 | Pharm. Res. | pmid:3509887 |
Nishimura T et al. | The role of lymphokine-activated cell-associated antigen. II. Distribution and correlation with cell cycle. | 1987 | Cell. Immunol. | pmid:3495348 |
Moebius U et al. | Butyrate-synchronized cloned T cells retain their dependence on interleukin-2 for growth induction. A model system for growth regulation. | 1987 | Exp. Cell Res. | pmid:3493914 |
Maruo T et al. | Discordant induction of tumor-associated antigen, TA-4 and chorionic gonadotropin beta in cultured cervical carcinoma cells. | 1987 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:3493311 |
Roediger WE et al. | Specific metabolic effect of sodium nitrite on fat metabolism by mucosal cells of the colon. | 1986 | Dig. Dis. Sci. | pmid:3486100 |
Hollander D et al. | Transport of butyric acid in vascularly perfused anuran small intestine: importance of pH and anion transport. | 1986 | Am. J. Physiol. | pmid:3485924 |
Hong SJ and Ko LW | Activation of protein expression in clonal glioma cells by sodium butyrate. | 1987 | Gaoxiong Yi Xue Ke Xue Za Zhi | pmid:3482265 |
Alitalo R | The bcr-c-abl tyrosine kinase activity is extinguished by TPA in K562 leukemia cells. | 1987 | FEBS Lett. | pmid:3477472 |
Rouault TA et al. | Influence of altered transcription on the translational control of human ferritin expression. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3476949 |
Seigneurin D et al. | Human chronic myeloid leukemic cell line with positive Philadelphia chromosome exhibits megakaryocytic and erythroid characteristics. | 1987 | Exp. Hematol. | pmid:3476310 |
Alitalo R et al. | Induction of platelet-derived growth factor gene expression during megakaryoblastic and monocytic differentiation of human leukemia cell lines. | 1987 | EMBO J. | pmid:3475202 |
Zucker RM et al. | Differential hemoglobin synthesis in murine erythroleukemic cells: hemin effects. | 1987 | Cell Biochem. Funct. | pmid:3469035 |
Zajac-Kaye M et al. | Induction of differentiation in Friend erythroleukemia cells with dimethyl sulfoxide, hexamethylene bisacetamide and sodium butyrate is not accompanied by changes in proviral DNA or its expression. | 1986 | Virus Res. | pmid:3467519 |
Friend C et al. | Depletion of sodium butyrate from the culture medium of Friend erythroleukemia cells undergoing differentiation. | 1987 | Cancer Res. | pmid:3466690 |
Ross DW et al. | Leukemic cell maturation: variability of the myeloid leukemic cell phenotype. | 1986 | Blood Cells | pmid:3466656 |
Protić-Sabljić M and Kraemer KH | Host cell reactivation by human cells of DNA expression vectors damaged by ultraviolet radiation or by acid-heat treatment. | 1986 | Carcinogenesis | pmid:3463438 |
Warren L | Sialic acid lyase in human promyelocytic leukemic cells (HL-60) during phorbol-ester-induced differentiation. | 1986 | Biochim. Biophys. Acta | pmid:3463364 |
Ovitt CE et al. | Expression of different-sized placental alkaline phosphatase mRNAs in placenta and choriocarcinoma cells. | 1986 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3459156 |
Okabe-Kado J et al. | Enhancement by hemin of the sensitivity of K562 human leukemic cells to 1-beta-D-arabinofuranosylcytosine. | 1986 | Cancer Res. | pmid:3455882 |
Corin RE et al. | Antagonistic effect of butyrate on hexamethylene bisacetamide induced differentiation of murine erythroleukemia cells. | 1986 | Cancer Res. | pmid:3455880 |
Galenko-IaroshevckiÄ PA et al. | [Complex formation of lithium hydroxybutyrate with ions of Na+, K+, Ba2+, Mg2+, and Ca2+]. | 1987 Nov-Dec | Farmakol Toksikol | pmid:3436425 |
Birren BW et al. | Butyrate-induced changes in nuclease sensitivity of chromatin cannot be correlated with transcriptional activation. | 1987 | Mol. Cell. Biol. | pmid:3431545 |
Steels PS and Boulpaep EL | pH-dependent electrical properties and buffer permeability of the Necturus renal proximal tubule cell. | 1987 | J. Membr. Biol. | pmid:3430572 |