butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lee KL et al. | The effects of sodium butyrate on the retinoic acid-induced changes in 1,25-dihydroxyvitamin D3 receptors in tumorigenic and nontumorigenic bone derived cell lines. | 1988 | Endocrinology | pmid:2836162 |
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Rodgers RJ et al. | Secretion of progesterone and prostaglandins by cells of bovine corpora lutea from three stages of the luteal phase. | 1988 | J. Endocrinol. | pmid:2842428 |
Kaneko Y et al. | Fibroblast-like transformation and c-myc gene alteration of human hepatocytes induced by novobiocin and butyrate. | 1988 | Biochem. Biophys. Res. Commun. | pmid:2843181 |
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Staecker JL and Pitot HC | The effect of sodium butyrate on tyrosine aminotransferase induction in primary cultures of normal adult rat hepatocytes. | 1988 | Arch. Biochem. Biophys. | pmid:2895606 |
Drucker DJ et al. | Proglucagon gene expression and posttranslational processing in a hamster islet cell line. | 1988 | Endocrinology | pmid:3416818 |
Szabad J et al. | The effects of two mutations connected with chromatin functions on female germ-line cells of Drosophila. | 1988 | Mol. Gen. Genet. | pmid:3422705 |
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Effects of short-chain fatty acids on a human colon carcinoma cell line. | 1988 | Nutr. Rev. | pmid:3340339 | |
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Bägli DJ et al. | Natural killer sensitivity of colorectal carcinoma targets. Correlation with degree of differentiation. | 1989 | Arch Surg | pmid:2910252 |
Corfield AP et al. | Selection of radioactive precursors for metabolic labelling of mucus glycoproteins. | 1989 | Biochem. Soc. Trans. | pmid:2628065 |
Bretton RH and Pennypacker JP | Butyric acid causes morphological changes in cultured chondrocytes through alterations in the extracellular matrix. | 1989 | J. Cell. Physiol. | pmid:2910883 |
Otaka M et al. | Antibody-mediated targeting of differentiation inducers to tumor cells: inhibition of colonic cancer cell growth in vitro and in vivo. A preliminary note. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2912449 |
Brass EP and Garrity MJ | Modulation of prostaglandin E2 catabolism and action by fuel substrates in rat hepatocytes. | 1989 | Biochim. Biophys. Acta | pmid:2912505 |
Perrine SP et al. | Butyric acid modulates developmental globin gene switching in man and sheep. | 1989 | Adv. Exp. Med. Biol. | pmid:2484761 |
Wiese B and Martin K | Basic extraction studies of benzylpenicillin and its determination by liquid chromatography with pre-column derivatisation. | 1989 | J Pharm Biomed Anal | pmid:2488609 |
Matsuhisa T et al. | Induction of blood coagulation factor VIII by sodium butyrate in Balb/c 3T3 cells. | 1989 | Exp. Cell Res. | pmid:2491813 |
Durie BG et al. | Myelomonocytic myeloma cell line (LB 84-1). | 1989 | Blood | pmid:2492835 |
Dorner AJ et al. | Increased synthesis of secreted proteins induces expression of glucose-regulated proteins in butyrate-treated Chinese hamster ovary cells. | 1989 | J. Biol. Chem. | pmid:2511206 |
Crabtree B et al. | Evidence that the production of acetate in rat hepatocytes is a predominantly cytoplasmic process. | 1989 | Biochem. J. | pmid:2564776 |
Kone P et al. | Effect of the combination of monensin and isoacids on rumen fermentation in vitro. | 1989 | J. Dairy Sci. | pmid:2600235 |
Schulz M et al. | Regulation by dibutyryl cyclic AMP of carnosine synthesis in astroglia-rich primary cultures kept in serum-free medium. | 1989 | J. Neurochem. | pmid:2462017 |
Matsui-Yuasa I et al. | Two mechanisms of spermidine/spermine N1-acetyltransferase-induction. | 1989 | Arch. Biochem. Biophys. | pmid:2463788 |
Cox GS and Park KH | Modulation of glycoprotein hormone alpha-subunit levels, alkaline phosphatase activity, and DNA replication by antimetabolites in HeLa cultures. | 1989 | Arch. Biochem. Biophys. | pmid:2463791 |
Shimamura A and Worcel A | The assembly of regularly spaced nucleosomes in the Xenopus oocyte S-150 extract is accompanied by deacetylation of histone H4. | 1989 | J. Biol. Chem. | pmid:2760072 |
Chatham JC et al. | The metabolic consequences of hydroperoxide perfusion on the isolated rat heart. | 1989 | Eur. J. Biochem. | pmid:2806248 |
Jenkins DJ | The link between colon fermentation and systemic disease. | 1989 | Am. J. Gastroenterol. | pmid:2816871 |
Aizawa K et al. | Placental alkaline phosphatase-like isoenzymes produced by human gastric cancer cells. | 1989 | Acta Pathol. Jpn. | pmid:2686348 |
Tanaka Y et al. | Enhancement of butyrate-induced differentiation of HT-29 human colon carcinoma cells by 1,25-dihydroxyvitamin D3. | 1989 | Biochem. Pharmacol. | pmid:2688649 |
Flatow U et al. | Characterization and tumorigenicity of a butyrate-adapted T24 bladder cancer cell line. | 1989 | Cancer Invest. | pmid:2695227 |
Neogrády Z et al. | Effect of intraruminal butyrate infusion on the plasma insulin level in sheep. | 1989 | Acta Vet. Hung. | pmid:2697146 |
Gardner SL et al. | Modulation by sodium butyrate of the differentiated status of a clonal pancreatic B-cell line (RIN). | 1989 | Diabetes Res. | pmid:2699445 |
Neogrády S et al. | The effects of butyrate and glucagon on the proliferation of ruminal epithelial cells in culture. | 1989 | Vet. Res. Commun. | pmid:2773302 |
Newman JD et al. | Induction of the insulin receptor and other differentiation markers by sodium butyrate in the Burkitt lymphoma cell, Raji. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2786417 |
Kojima S et al. | Identification of myeloid origin in undifferentiated congenital leukemia by in vitro marrow culture study. | 1989 | Am J Pediatr Hematol Oncol | pmid:2782565 |
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Gerharz CD et al. | Heterogeneous response to differentiation induction with different polar compounds in a clonal rat rhabdomyosarcoma cell line (BA-HAN-1C). | 1989 | Br. J. Cancer | pmid:2803927 |
Herz F and Halwer M | Modulation of alkaline phosphatases in LoVo, a human colon carcinoma cell line. | 1989 | Biochim. Biophys. Acta | pmid:2804087 |
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James DE et al. | Isoproterenol stimulates phosphorylation of the insulin-regulatable glucose transporter in rat adipocytes. | 1989 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2554313 |
Lotan R et al. | Modulation of galactoside-binding lectins in tumor cells by differentiation-inducing agents. | 1989 | Cancer Lett. | pmid:2555043 |
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Nakamura CV and Pinto AS | Biological effects of lithium chloride on the insect trypanosomatid Herpetomonas samuelpessoai. | 1989 | Parasitology | pmid:2556681 |
KraevskiÄ VA et al. | [Oscillatory changes in the transcription and supercoiling of minichromosomal DNA after the withdrawal of butyric acid from a mouse cell culture]. | 1989 | Dokl. Akad. Nauk SSSR | pmid:2635665 |
Elliott WL et al. | Testing for cell surface forms of class II major histocompatibility complex antigens and Ii by radioiodination, biotinylation, and membrane immunofluorescence. | 1989 | Am. J. Hematol. | pmid:2642651 |
Neogrády S et al. | Effects of butyrate and insulin and their interaction on the DNA synthesis of rumen epithelial cells in culture. | 1989 | Experientia | pmid:2643531 |
Herman MM et al. | Neuroblastic differentiation potential of the human retinoblastoma cell lines Y-79 and WERI-Rb1 maintained in an organ culture system. An immunohistochemical, electron microscopic, and biochemical study. | 1989 | Am. J. Pathol. | pmid:2643884 |
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Chander A | Regulation of lung surfactant secretion by intracellular pH. | 1989 | Am. J. Physiol. | pmid:2514603 |
Daniel P et al. | Pharmacokinetic study of butyric acid administered in vivo as sodium and arginine butyrate salts. | 1989 | Clin. Chim. Acta | pmid:2667816 |
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Stoddart JH et al. | Sodium butyrate suppresses the transforming activity of an activated N-ras oncogene in human colon carcinoma cells. | 1989 | Exp. Cell Res. | pmid:2676572 |
Walker-Jones D et al. | Stimulation of epithelial membrane antigen expression by transforming growth factor-beta in normal and oncogene-transformed human mammary epithelial cells. | 1989 | Cancer Res. | pmid:2680064 |
Resnicoff M and Medrano EE | Growth factors and hormones which affect survival, growth, and differentiation of the MCF-7 stem cells and their descendants. | 1989 | Exp. Cell Res. | pmid:2645148 |
Gladhaug IP and Christoffersen T | n-butyrate and dexamethasone synergistically modulate the surface expression of epidermal growth factor receptors in cultured rat hepatocytes. | 1989 | FEBS Lett. | pmid:2646145 |
Hargreaves AJ et al. | Sodium butyrate induces major morphological changes in C6 glioma cells that are correlated with increased synthesis of a spectrin-like protein. | 1989 | Brain Res. Dev. Brain Res. | pmid:2653664 |
Turner BM | Acetylation and deacetylation of histone H4 continue through metaphase with depletion of more-acetylated isoforms and altered site usage. | 1989 | Exp. Cell Res. | pmid:2653852 |
Rome L et al. | Proximal tubule volume regulation in hyperosmotic media: intracellular K+, Na+, and Cl-. | 1989 | Am. J. Physiol. | pmid:2610250 |
Staiano-Coico L et al. | Sodium-N-butyrate induces cytoskeletal rearrangements and formation of cornified envelopes in cultured adult human keratinocytes. | 1989 | Cell Tissue Kinet | pmid:2611852 |
Garrison JC et al. | Computer-based image analysis of cartilage differentiation in embryonic limb bud micromass cultures. | 1989 | J Microsc | pmid:2614818 |
Szatkowski MS and Thomas RC | The intrinsic intracellular H+ buffering power of snail neurones. | 1989 | J. Physiol. (Lond.) | pmid:2585301 |