butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Anaplasia D000708 1 associated lipids
Trophoblastic Neoplasms D014328 1 associated lipids
Diverticulitis, Colonic D004239 1 associated lipids
Aphakia, Postcataract D001036 1 associated lipids
Diverticulosis, Colonic D043963 1 associated lipids
Facial Injuries D005151 1 associated lipids
Gastrinoma D015408 1 associated lipids
Proctitis D011349 1 associated lipids
Myoepithelioma D009208 1 associated lipids
Astigmatism D001251 1 associated lipids
Diverticulitis D004238 1 associated lipids
Salivary Gland Neoplasms D012468 1 associated lipids
Glycogen Storage Disease Type II D006009 2 associated lipids
Hemorrhoids D006484 2 associated lipids
Colorectal Neoplasms, Hereditary Nonpolyposis D003123 2 associated lipids
Lymphoma, AIDS-Related D016483 2 associated lipids
Sarcoma, Avian D001357 2 associated lipids
Intestinal Neoplasms D007414 2 associated lipids
Nevus D009506 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Dentin, Secondary D003809 2 associated lipids
Urea Cycle Disorders, Inborn D056806 2 associated lipids
Pouchitis D019449 3 associated lipids
Prostatic Neoplasms, Castration-Resistant D064129 3 associated lipids
Adenocarcinoma, Follicular D018263 3 associated lipids
Pregnancy in Diabetics D011254 3 associated lipids
Psychophysiologic Disorders D011602 3 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Hypereosinophilic Syndrome D017681 3 associated lipids
Epstein-Barr Virus Infections D020031 3 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Nose Neoplasms D009669 3 associated lipids
Retinal Neoplasms D019572 3 associated lipids
Multiple Chemical Sensitivity D018777 4 associated lipids
Dysentery D004403 4 associated lipids
Disease Models, Animal D004195 4 associated lipids
Marek Disease D008380 4 associated lipids
Herpesviridae Infections D006566 4 associated lipids
Nasopharyngeal Neoplasms D009303 4 associated lipids
Retroviridae Infections D012192 4 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Milk Hypersensitivity D016269 4 associated lipids
Neoplastic Cells, Circulating D009360 5 associated lipids
Strongylida Infections D017206 5 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Dental Leakage D003763 5 associated lipids
Fragile X Syndrome D005600 5 associated lipids
Ataxia Telangiectasia D001260 6 associated lipids
Xeroderma Pigmentosum D014983 6 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

Download all related citations
Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Kameyama T et al. [Behavioral pharmacological action of Ca-4-(3,5-dihydroxy-3-methylpenthylamido) butyrate (mevalonic GABA, MV-GABA)]. 1987 Nippon Yakurigaku Zasshi pmid:3034749
Anisimová E et al. Chemically purified serum factor can induce both Epstein-Barr virus antigen synthesis and cell differentiation. 1987 Arch. Virol. pmid:3034214
Van Dyck E and Piot P Enzyme profile of Haemophilus ducreyi strains isolated on different continents. 1987 Eur. J. Clin. Microbiol. pmid:3032608
Matta-el-Ammouri G et al. Effects of butyric and acetic acids on acetone-butanol formation by Clostridium acetobutylicum. 1987 Biochimie pmid:3032286
Wiegandt H et al. Retinoic acid alters the metabolic 3H-labelling of glycosphingolipids. 1987 Biochem. Biophys. Res. Commun. pmid:3032172
Grippo JF and Gudas LJ The effect of dibutyryl cyclic AMP and butyrate on F9 teratocarcinoma cellular retinoic acid-binding protein activity. 1987 J. Biol. Chem. pmid:3031026
Nègre A et al. Acyl-chain specificity and properties of cholesterol esterases from normal and Wolman lymphoid cell lines. 1987 Biochim. Biophys. Acta pmid:3030438
Hatayama T et al. Effects of sodium butyrate and dibutyryl cyclic AMP on thermosensitivity of HeLa cells and their production of heat shock proteins. 1986 Biochem. Int. pmid:3028421
Furukawa M et al. Epstein-Barr virus early antigen induction in nasopharyngeal hybrid cells by Chinese medicinal herbs. 1986 Auris Nasus Larynx pmid:3028348
Dobson DE et al. Nucleotide sequence and hormonal regulation of mouse glycerophosphate dehydrogenase mRNA during adipocyte and muscle cell differentiation. 1987 J. Biol. Chem. pmid:3027100
Hartmanis MG Butyrate kinase from Clostridium acetobutylicum. 1987 J. Biol. Chem. pmid:3027059
Jacobs LR Relationship between dietary fiber and cancer: metabolic, physiologic, and cellular mechanisms. 1986 Proc. Soc. Exp. Biol. Med. pmid:3025886
Jentsch TJ et al. Electrical properties of sodium bicarbonate symport in kidney epithelial cells (BSC-1). 1986 Am. J. Physiol. pmid:3024506
Ash RJ Butyrate-induced reversal of herpes simplex virus restriction in neuroblastoma cells. 1986 Virology pmid:3024402
Rando RF et al. The noncoding region of HPV-6vc contains two distinct transcriptional enhancing elements. 1986 Virology pmid:3024399
Yen A et al. Control of HL-60 monocytic differentiation. Different pathways and uncoupled expression of differentiation markers. 1987 Exp. Cell Res. pmid:3023118
Nambi P et al. Induction of functional beta-adrenergic receptors in rat aortic smooth muscle cells by sodium butyrate. 1986 Biochem. Pharmacol. pmid:3022740
Stanton RC et al. Use of monoclonal antibodies to culture rat proximal tubule cells. 1986 Am. J. Physiol. pmid:3022594
Kress H et al. Butyrate induced accumulation of a 2.3 kb polyadenylated H1(0) histone mRNA in HeLa cells. 1986 Nucleic Acids Res. pmid:3020508
Sculley DG et al. Reactions of sera from patients with rheumatoid arthritis, systemic lupus erythematosus and infectious mononucleosis to Epstein-Barr virus-induced polypeptides. 1986 J. Gen. Virol. pmid:3020161
Tan RS et al. Demonstration of Epstein-Barr virus-specific DNA polymerase in chemically induced Raji cells and its antibody in serum from patients with nasopharyngeal carcinoma. 1986 Cancer Res. pmid:3019519
Mori Y et al. Differential effect of sodium butyrate on cyclic AMP phosphodiesterase activities in butyrate sensitive and resistant mastocytoma cells. 1986 Biochem. Biophys. Res. Commun. pmid:3019329
Andrews PW et al. Differentiation of TERA-2 human embryonal carcinoma cells into neurons and HCMV permissive cells. Induction by agents other than retinoic acid. 1986 Differentiation pmid:3017799
Lazarus AH and Baines MG Studies on the mechanism of specificity of human natural killer cells for tumor cells: correlation between target cell transferrin receptor expression and competitive activity. 1985 Cell. Immunol. pmid:3017573
Rama BN and Prasad KN Modification of the hyperthermic response on neuroblastoma cells by cAMP and sodium butyrate. 1986 Cancer pmid:3017539
Kyritsis AP et al. Laminin: an initiating role in retinoblastoma cell attachment and differentiation. 1986 In Vitro Cell. Dev. Biol. pmid:3015863
McCachren SS et al. Dibutyryl cyclic adenosine monophosphate reduces expression of c-myc during HL-60 differentiation. 1986 Blood pmid:3015282
Comte J et al. Reversal of glucose-induced inhibition of newborn rat liver mitochondrial maturation by administration of alkylxanthines at birth. 1986 Biochem. Pharmacol. pmid:3015149
Jensen BD et al. The efficiencies of the component steps of oxidative phosphorylation. II. Experimental determination of the efficiencies in mitochondria and examination of the equivalence of membrane potential and pH gradient in phosphorylation. 1986 Arch. Biochem. Biophys. pmid:3015029
Niles RM Chemical induction of tumor cell differentiation. 1985 Surv Synth Pathol Res pmid:3014630
Tsokos M et al. Differentiation of human retinoblastoma in vitro into cell types with characteristics observed in embryonal or mature retina. 1986 Am. J. Pathol. pmid:3013012
Wang DS et al. [The biological effects of sodium butyrate on cultured human stomach cancer cells and esophageal cancer cells]. 1985 Shi Yan Sheng Wu Xue Bao pmid:3012915
Voutilainen R et al. Hormonal regulation of P450scc (20,22-desmolase) and P450c17 (17 alpha-hydroxylase/17,20-lyase) in cultured human granulosa cells. 1986 J. Clin. Endocrinol. Metab. pmid:3011839
Petraki H et al. Loss and reappearance of transferrin receptors in human leukemic cell lines. 1986 Exp. Cell Biol. pmid:3011533
Fiehn NE Enzyme activities from eight small-sized oral spirochetes. 1986 Scand J Dent Res pmid:3010439
Ooka T et al. Epstein-Barr virus-specific DNA polymerase in virus-nonproducer Raji cells. 1986 J. Virol. pmid:3009879
Gambari R et al. Human leukemic K562 cells: suppression of hemoglobin accumulation by a monoclonal antibody to human transferrin receptor. 1986 Biochim. Biophys. Acta pmid:3008852
Colucci WS Adenosine 3',5'-cyclic-monophosphate-dependent regulation of alpha 1-adrenergic receptor number in rabbit aortic smooth muscle cells. 1986 Circ. Res. pmid:3004780
Yokochi T et al. Differential expression of Epstein-Barr virus membrane antigens defined with monoclonal antibodies. 1986 Virology pmid:3002025
Harnett GB et al. A modified immunofluorescence test for Epstein-Barr virus-specific IgM antibody. 1985 J. Virol. Methods pmid:3001120
Azuma M et al. Emergence of differentiated subclones from a human salivary adenocarcinoma cell clone in culture after treatment with sodium butyrate. 1986 Cancer Res. pmid:3000585
Kassis S Modulation of the receptor-coupled adenylate cyclase system in HeLa cells by sodium butyrate. 1985 Biochemistry pmid:3000434
Mitsudomi T and Kimura G Effects of sodium n-butyrate on entry into S phase in resting rat 3Y1 cells infected with simian virus 40. 1985 J. Virol. pmid:2999448
Cole NA and Hutcheson DP Influence of realimentation diet on recovery of rumen activity and feed intake in beef steers. 1985 J. Anim. Sci. pmid:2999054
Asai S et al. Ultrastructural studies on cell fusion induced by Epstein-Barr virus or N-butyrate and 12-O-tetradecanoylphorbol-13-acetate. Brief report. 1985 Arch. Virol. pmid:2998304
Kumar S et al. Glucocorticoids regulate the transcription of glycerol phosphate dehydrogenase in cultured glial cells. 1985 J. Biol. Chem. pmid:2997222
Takimoto T et al. Effects of human interferon on cell proliferation and antigens induced by Epstein-Barr virus in epithelial hybrid cells derived from nasopharyngeal carcinoma. 1985 Otolaryngol Head Neck Surg pmid:2995902
Heasley LE and Brunton LL Prostaglandin A1 metabolism and inhibition of cyclic AMP extrusion by avian erythrocytes. 1985 J. Biol. Chem. pmid:2995340
Radsak K et al. Sodium butyrate selectively inhibits host cell glycoprotein synthesis in human fibroblasts infected with cytomegalovirus. 1985 Biosci. Rep. pmid:2994773
Imai A and Gershengorn MC Evidence for tight coupling of thyrotropin-releasing hormone receptors to stimulated inositol trisphosphate formation in rat pituitary cells. 1985 J. Biol. Chem. pmid:2993279
Roubalová K et al. Effects of activated serum factor on the induction of Epstein-Barr virus antigens and cell differentiation. 1985 Arch. Virol. pmid:2990391
Hartter DE and Ramirez VD Responsiveness of immature versus adult male rat hypothalami to dibutyryl cyclic AMP- and forskolin-induced LHRH release in vitro. 1985 Neuroendocrinology pmid:2989724
Cowley G et al. Production of beta-human chorionic gonadotrophin by human squamous carcinoma cell lines. 1985 Int. J. Cancer pmid:2987135
Daniel P and Pieri F [Inhibitory effect of sodium butyrate on the in vitro growth of Herpes virus hominis, type I]. 1985 C. R. Acad. Sci. III, Sci. Vie pmid:2986799
Lau KH et al. A mouse tumor-derived osteolytic factor stimulates bone resorption by a mechanism involving local prostaglandins production in bone. 1985 Biochim. Biophys. Acta pmid:2986710
Beckner SK et al. Induction of glucagon responsiveness in transformed MDCK cells unresponsive to glucagon. 1985 Meth. Enzymol. pmid:2985924
Kallin B et al. Purification of Epstein-Barr virus DNA polymerase from P3HR-1 cells. 1985 J. Virol. pmid:2985818
Lozzio CB et al. Effects of sodium butyrate on human chronic myelogenous leukaemia cell line K562. 1979 Nature pmid:298333
Yuan ZA et al. Effect of butyrate on the expression of microinjected or transfected genes. 1985 J. Biol. Chem. pmid:2982877
Kawanishi M and Ito Y Alkaline deoxyribonuclease induced with diterpene ester TPA and n-butyrate in Epstein-Barr virus genome-carrying Raji cells. 1985 Intervirology pmid:2982761
Roubalová K and Roubal J Effect of n-butyrate on transformation of human lymphocytes by Epstein-Barr virus. 1985 Intervirology pmid:2982760
Fujita J et al. Enhanced expression of Epstein-Barr virus early antigens by antitubulin agents in a latently infected human lymphoblastoid cell line. 1985 Experientia pmid:2982647
Almlöf I et al. Induction of basophilic differentiation in the human basophilic cell line KU812. 1988 Scand. J. Immunol. pmid:2973655
Chan WC et al. Large granular lymphocyte proliferation: an analysis of T-cell receptor gene arrangement and expression and the effect of in vitro culture with inducing agents. 1988 Blood pmid:2961380
Malik H et al. Chemical inducers of differentiation, dimethylsulfoxide, butyric acid, and dimethylthiourea, induce selective ultrastructural patterns in B16 melanoma cells. 1987 Biol. Cell pmid:2960403
Braun PC et al. Effect of cerulenin and sodium butyrate on chitin synthesis in Candida albicans. 1987 Can. J. Microbiol. pmid:2957042
Fraser JK and Berridge MV Induction of B-lymphocyte antigens on the chronic myeloid leukemic cell line K562 using sodium butyrate. 1987 Exp. Hematol. pmid:2952519
Ronot X and Adolphe M Modulating effects of drugs on cell cycle kinetics. 1986 Biol. Cell pmid:2950954
Chang G et al. Dietary Sodium Butyrate Supplementation Reduces High-Concentrate Diet Feeding-Induced Apoptosis in Mammary Cells in Dairy Goats. 2018 J. Agric. Food Chem. pmid:29446933
Hidaka M et al. Three lysophosphatidic acids with a distinct long chain moiety differently affect cell differentiation of human colon epithelial cells to goblet cells. 2018 Life Sci. pmid:29412173
Hannah SM and Stern MD Effect of supplemental niacin or niacinamide and soybean source on ruminal bacterial fermentation in continuous culture. 1985 J. Anim. Sci. pmid:2934360
Bryant G et al. Butyrate induced reduction of tumor cell laminin receptors. 1986 Cancer Res. pmid:2934129
Montiel F et al. Presence of insulin receptors in cultured glial C6 cells. Regulation by butyrate. 1989 Biochem. J. pmid:2930502
Thakur MK and Prasad S Age-specific methylation of high-mobility-group proteins of the rat liver and its modulation by spermine and sodium butyrate. 1989 Mutat. Res. pmid:2927415
Binder HJ and Mehta P Short-chain fatty acids stimulate active sodium and chloride absorption in vitro in the rat distal colon. 1989 Gastroenterology pmid:2925072
Casper D and Davies P Mechanism of activation of choline acetyltransferase in a human neuroblastoma cell line. 1989 Brain Res. pmid:2924124
Casper D and Davies P Stimulation of choline acetyltransferase activity by retinoic acid and sodium butyrate in a cultured human neuroblastoma. 1989 Brain Res. pmid:2924123
Nackerdien Z et al. Chromatin decondensed by acetylation shows an elevated radiation response. 1989 Radiat. Res. pmid:2922469
Weaver GA et al. Constancy of glucose and starch fermentations by two different human faecal microbial communities. 1989 Gut pmid:2920921
Higgins PJ and Ryan MP Biochemical localization of the transformation-sensitive 52 kDa (p52) protein to the substratum contact regions of cultured rat fibroblasts. Butyrate induction, characterization, and quantification of p52 in v-ras transformed cells. 1989 Biochem. J. pmid:2920008
Anantharaju PG et al. Induction of colon and cervical cancer cell death by cinnamic acid derivatives is mediated through the inhibition of Histone Deacetylases (HDAC). 2017 PLoS ONE pmid:29190639
Vaziri ND et al. Effect of experimental azotemia on intestinal transport of butyric acid. 1989 Proc. Soc. Exp. Biol. Med. pmid:2915995
Hoffman R et al. Induction of erythropoietic colonies in a human chronic myelogenous leukemia cell line. 1979 Blood pmid:291442
Brass EP and Garrity MJ Modulation of prostaglandin E2 catabolism and action by fuel substrates in rat hepatocytes. 1989 Biochim. Biophys. Acta pmid:2912505
Otaka M et al. Antibody-mediated targeting of differentiation inducers to tumor cells: inhibition of colonic cancer cell growth in vitro and in vivo. A preliminary note. 1989 Biochem. Biophys. Res. Commun. pmid:2912449
Machado CF et al. Conditional Deletion of in Olfactory Sensory Neurons Leads to Olfactory Impairment. 2017 J. Neurosci. pmid:29118104
Bretton RH and Pennypacker JP Butyric acid causes morphological changes in cultured chondrocytes through alterations in the extracellular matrix. 1989 J. Cell. Physiol. pmid:2910883
Chen HM and Lifschitz CH Preparation of fecal samples for assay of volatile fatty acids by gas-liquid chromatography and high-performance liquid chromatography. 1989 Clin. Chem. pmid:2910583
Bägli DJ et al. Natural killer sensitivity of colorectal carcinoma targets. Correlation with degree of differentiation. 1989 Arch Surg pmid:2910252
Gonçalves E et al. Triiodothyronine transport into differentiated and undifferentiated mouse neuroblastoma cells (NB41A3). 1989 Endocrinology pmid:2909368
Tocco DJ et al. The physiological disposition of aerosolized 4-[(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl]-gamma -oxobenzenebutanoate (L-648,051) in rats. 1988 Sep-Oct Drug Metab. Dispos. pmid:2906592
Tocco DJ et al. Disposition and metabolism of sodium 4-[(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl]-gamma -oxobenzenebutanoate in rats and dogs. 1988 Sep-Oct Drug Metab. Dispos. pmid:2906591
Kobayashi H et al. Clostridium pabulibutyricum sp. nov., a butyric-acid-producing organism isolated from high-moisture grass silage. 2017 Int. J. Syst. Evol. Microbiol. pmid:29034861
Maddox AM and Haddox MK Characteristics of cyclic AMP enhancement of retinoic acid induction of increased transglutaminase activity in HL60 cells. 1988 Exp. Cell Biol. pmid:2903078
Staecker JL et al. Sodium butyrate preserves aspects of the differentiated phenotype of normal adult rat hepatocytes in culture. 1988 J. Cell. Physiol. pmid:2899578
Seifrtová M et al. Haemanthamine alters sodium butyrate-induced histone acetylation, p21 expression, Chk1 and Chk2 activation and leads to increased growth inhibition and death in A2780 ovarian cancer cells. 2017 Phytomedicine pmid:28991639
Staecker JL and Pitot HC The effect of sodium butyrate on tyrosine aminotransferase induction in primary cultures of normal adult rat hepatocytes. 1988 Arch. Biochem. Biophys. pmid:2895606
Sałkowska A et al. Differentiation stage-specific effect of histone deacetylase inhibitors on the expression of RORγT in human lymphocytes. 2017 J. Leukoc. Biol. pmid:28951421
Wu Q et al. Tailoring the Oxidative Stress Tolerance of Clostridium tyrobutyricum CCTCC W428 by Introducing Trehalose Biosynthetic Capability. 2017 J. Agric. Food Chem. pmid:28925260
da Silva JS et al. Nutritive value and fermentation quality of palisadegrass and stylo mixed silages. 2018 Anim. Sci. J. pmid:28905506