butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
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Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Santini V et al. | Butyrate-stable monosaccharide derivatives induce maturation and apoptosis in human acute myeloid leukaemia cells. | 1998 | Br. J. Haematol. | pmid:9633898 |
| Caderni G et al. | Slow-release pellets of sodium butyrate increase apoptosis in the colon of rats treated with azoxymethane, without affecting aberrant crypt foci and colonic proliferation. | 1998 | Nutr Cancer | pmid:9631487 |
| Tsumura H et al. | Mouse alloantigen Ly10 is identical to murine fusion regulatory protein-1 (mFRP-1)/4F2/CD98: aberrant expression of mFRP-1/Ly10 allotypes in cells derived from CDF1 mice due to the gene deletion. | 1998 | Cell. Immunol. | pmid:9630841 |
| Smith JG et al. | Butyric acid from the diet: actions at the level of gene expression. | 1998 | Crit Rev Food Sci Nutr | pmid:9626487 |
| Yamamoto H et al. | Suppression of growth of hepatocellular carcinoma by sodium butyrate in vitro and in vivo. | 1998 | Int. J. Cancer | pmid:9626359 |
| Perez RV et al. | Selective targeting of Kupffer cells with liposomal butyrate augments portal venous transfusion-induced immunosuppression. | 1998 | Transplantation | pmid:9625008 |
| Archer SY et al. | p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9618491 |
| Cuisset L et al. | A protein phosphatase is involved in the inhibition of histone deacetylation by sodium butyrate. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9618285 |
| Walia H et al. | Histone acetylation is required to maintain the unfolded nucleosome structure associated with transcribing DNA. | 1998 | J. Biol. Chem. | pmid:9603965 |
| Matthews JB et al. | Na-K-2Cl cotransporter gene expression and function during enterocyte differentiation. Modulation of Cl- secretory capacity by butyrate. | 1998 | J. Clin. Invest. | pmid:9593763 |
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| Clark PR et al. | A novel drug screening assay for papillomavirus specific antiviral activity. | 1998 | Antiviral Res. | pmid:9588842 |
| Zhang M et al. | Heat-induced proteolysis of HSF causes premature deactivation of the heat shock response in Nb2 lymphoma cells. | 1998 | Cell Stress Chaperones | pmid:9585182 |
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| Krishnan S and Ramakrishna BS | Butyrate and glucose metabolism in isolated colonocytes in the developing rat colon. | 1998 | J. Pediatr. Gastroenterol. Nutr. | pmid:9552140 |
| Krishnan S et al. | The ability of enteric diarrhoeal pathogens to ferment starch to short-chain fatty acids in vitro. | 1998 | Scand. J. Gastroenterol. | pmid:9548615 |
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| Giardina C and Inan MS | Nonsteroidal anti-inflammatory drugs, short-chain fatty acids, and reactive oxygen metabolism in human colorectal cancer cells. | 1998 | Biochim. Biophys. Acta | pmid:9540818 |
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| Komatsu Y and Hayashi H | Histone deacetylase inhibitors up-regulate the expression of cell surface MHC class-I molecules in B16/BL6 cells. | 1998 | J. Antibiot. | pmid:9531994 |
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| Johnstone RM et al. | Loss of glucose transport in developing avian red cells. | 1998 | Eur. J. Cell Biol. | pmid:9523157 |
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| Basson MD et al. | Differential modulation of human (Caco-2) colon cancer cell line phenotype by short chain fatty acids. | 1998 | Proc. Soc. Exp. Biol. Med. | pmid:9521097 |
| Moore-Hoon ML and Turner RJ | Increased expression of the secretory Na+-K+-2Cl- cotransporter with differentiation of a human intestinal cell line. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9514875 |
| Ritzhaupt A et al. | The characterization of butyrate transport across pig and human colonic luminal membrane. | 1998 | J. Physiol. (Lond.) | pmid:9508842 |
| Emiliani S et al. | Characterization of a human RPD3 ortholog, HDAC3. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9501169 |
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| Dong-Le Bourhis X et al. | Transforming growth factor beta 1 and sodium butyrate differentially modulate urokinase plasminogen activator and plasminogen activator inhibitor-1 in human breast normal and cancer cells. | 1998 | Br. J. Cancer | pmid:9472634 |
| Yamamoto I et al. | Interleukin-2-dependent augmentation of the anti-TNP antibody production by sodium butyrate in cultured murine splenic B cells. | 1997 | Int. J. Immunopharmacol. | pmid:9467754 |
| Yamane M et al. | Docosahexaenoic/arachidonic acid omega-hydroxylation system and differentiation in the human colonic adenocarcinoma cell line, Caco-2. | 1998 | Cancer Lett. | pmid:9464491 |
| Shimizu A et al. | CyclinG contributes to G2/M arrest of cells in response to DNA damage. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9464250 |
| Gillenwater A et al. | Modulation of galectin-1 content in human head and neck squamous carcinoma cells by sodium butyrate. | 1998 | Int. J. Cancer | pmid:9462711 |
| Llorente A et al. | Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus. | 1998 | J. Cell Biol. | pmid:9456316 |
| Saleh AW and Hillen HF | Pharmacological induction of foetal haemoglobin synthesis in sickle-cell disease. | 1997 | Neth J Med | pmid:9455096 |
| Leber BF and Denburg JA | Retinoic acid modulation of induced basophil differentiation. | 1997 | Allergy | pmid:9450139 |
| Perez-Esteban J et al. | Lipase activity of Pseudomonas fluorescens in cold raw skim milk with different lipid supplements. | 1997 | Folia Microbiol. (Praha) | pmid:9449781 |
| Gupta KP and Mehrotra NK | Differential effects of butyric acid on mouse skin tumorigenesis. | 1997 | Biomed. Environ. Sci. | pmid:9448925 |
| Medina V et al. | Sodium butyrate inhibits carcinoma development in a 1,2-dimethylhydrazine-induced rat colon cancer. | 1998 Jan-Feb | JPEN J Parenter Enteral Nutr | pmid:9437648 |
| Ono M et al. | Resin glycosides. XXV. Multifidins I and II, new jalapins, from the seed of Quamoclit x multifida. | 1997 | Chem. Pharm. Bull. | pmid:9433765 |
| Yabushita H et al. | Emergence of an irreversible differentiated subclone from the poorly differentiated ovarian adenocarcinoma cell line AMOC-2 treated with sodium butyrate. | 1997 | J. Obstet. Gynaecol. Res. | pmid:9433040 |
| Callus BA et al. | Haemoglobin synthesis in erythropoietin-stimulated J2E cells does not require increased numbers of transferrin receptors. | 1997 | Eur. J. Biochem. | pmid:9428699 |
| Böhmig GA et al. | n-butyrate downregulates the stimulatory function of peripheral blood-derived antigen-presenting cells: a potential mechanism for modulating T-cell responses by short-chain fatty acids. | 1997 | Immunology | pmid:9415032 |
| Moore JW et al. | Thiolmethyltransferase activity in the human colonic mucosa: implications for ulcerative colitis. | 1997 | J. Gastroenterol. Hepatol. | pmid:9407333 |
| Cordel S et al. | 5-Fluorouracil-resistant colonic tumors are highly responsive to sodium butyrate/interleukin-2 bitherapy in rats. | 1997 | Int. J. Cancer | pmid:9399677 |