butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Anaplasia D000708 1 associated lipids
Trophoblastic Neoplasms D014328 1 associated lipids
Diverticulitis, Colonic D004239 1 associated lipids
Aphakia, Postcataract D001036 1 associated lipids
Diverticulosis, Colonic D043963 1 associated lipids
Facial Injuries D005151 1 associated lipids
Gastrinoma D015408 1 associated lipids
Myoepithelioma D009208 1 associated lipids
Proctitis D011349 1 associated lipids
Diverticulitis D004238 1 associated lipids
Salivary Gland Neoplasms D012468 1 associated lipids
Astigmatism D001251 1 associated lipids
Intestinal Neoplasms D007414 2 associated lipids
Hemorrhoids D006484 2 associated lipids
Lymphoma, AIDS-Related D016483 2 associated lipids
Sarcoma, Avian D001357 2 associated lipids
Dentin, Secondary D003809 2 associated lipids
Colorectal Neoplasms, Hereditary Nonpolyposis D003123 2 associated lipids
Nevus D009506 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Urea Cycle Disorders, Inborn D056806 2 associated lipids
Glycogen Storage Disease Type II D006009 2 associated lipids
Psychophysiologic Disorders D011602 3 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Epstein-Barr Virus Infections D020031 3 associated lipids
Hypereosinophilic Syndrome D017681 3 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Pregnancy in Diabetics D011254 3 associated lipids
Retinal Neoplasms D019572 3 associated lipids
Nose Neoplasms D009669 3 associated lipids
Prostatic Neoplasms, Castration-Resistant D064129 3 associated lipids
Pouchitis D019449 3 associated lipids
Adenocarcinoma, Follicular D018263 3 associated lipids
Disease Models, Animal D004195 4 associated lipids
Marek Disease D008380 4 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Herpesviridae Infections D006566 4 associated lipids
Nasopharyngeal Neoplasms D009303 4 associated lipids
Retroviridae Infections D012192 4 associated lipids
Milk Hypersensitivity D016269 4 associated lipids
Multiple Chemical Sensitivity D018777 4 associated lipids
Dysentery D004403 4 associated lipids
Strongylida Infections D017206 5 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Dental Leakage D003763 5 associated lipids
Fragile X Syndrome D005600 5 associated lipids
Neoplastic Cells, Circulating D009360 5 associated lipids
Ataxia Telangiectasia D001260 6 associated lipids
Xeroderma Pigmentosum D014983 6 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Authors Title Published Journal PubMed Link
Palmer DG et al. Modulation of p53 expression in cultured colonic adenoma cell lines by the naturally occurring lumenal factors butyrate and deoxycholate. 1997 Int. J. Cancer pmid:9398049
Vimard C et al. Changes in the sedimentation properties of acetycholinesterase during neuroblastoma differentiation. 1976 Biochimie pmid:938691
Hassig CA et al. Fiber-derived butyrate and the prevention of colon cancer. 1997 Chem. Biol. pmid:9384528
Onaga T et al. Effect of pituitary adenylate cyclase-activating polypeptide on exocrine and endocrine secretion in the ovine pancreas. 1996 Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. pmid:9375356
Coradini D et al. Effect of sodium butyrate on human breast cancer cell lines. 1997 Mar-Apr Cell Prolif. pmid:9375027
Faller DV and Perrine SP Butyrate in the treatment of sickle cell disease and beta-thalassemia. 1995 Curr. Opin. Hematol. pmid:9371980
Kolesnitchenko V et al. A major human immunodeficiency virus type 1-initiated killing pathway distinct from apoptosis. 1997 J. Virol. pmid:9371641
Velázquez OC et al. Butyrate inhibits deoxycholate-induced increase in colonic mucosal DNA and protein synthesis in vivo. 1997 Dis. Colon Rectum pmid:9369115
Payne KL et al. Modulation of T3-induced sex hormone-binding globulin secretion by human hepatoblastoma cells. 1997 Eur. J. Endocrinol. pmid:9368511
Singh M Calcium and cyclic nucleotide interaction in secretion of amylase from rat pancreas in vitro. 1979 J. Physiol. (Lond.) pmid:93637
Velázquez OC and Rombeau JL Butyrate. Potential role in colon cancer prevention and treatment. 1997 Adv. Exp. Med. Biol. pmid:9361842
Velázquez OC et al. Butyrate and the colonocyte. Production, absorption, metabolism, and therapeutic implications. 1997 Adv. Exp. Med. Biol. pmid:9361838
Barnard JA et al. Short chain fatty acid regulation of intestinal gene expression. 1997 Adv. Exp. Med. Biol. pmid:9361821
O'Mara FP et al. Rumen fermentation and nutrient flows for cows fed grass and grass supplemented with molassed beet pulp pellets. 1997 J. Dairy Sci. pmid:9361218
Kavaliers M et al. Opioid and non-opioid NMDA-mediated predator-induced analgesia in mice and the effects of parasitic infection. 1997 Brain Res. pmid:9359582
Loukopoulos D New therapies for the haemoglobinopathies. 1997 J Intern Med Suppl pmid:9350181
Vecchia MG et al. Acetate and propionate potentiate the antiproliferative effect of butyrate on RBL-2H3 growth. 1997 Gen. Pharmacol. pmid:9347317
Garcia-Bermejo L et al. Modulation of heat-shock protein 70 (HSP70) gene expression by sodium butyrate in U-937 promonocytic cells: relationships with differentiation and apoptosis. 1997 Exp. Cell Res. pmid:9344607
Sovová V et al. Differences of alkaline phosphatase and arginase activities in human colorectal carcinoma cell lines. 1997 Folia Biol. (Praha) pmid:9338115
Janson W et al. Butyrate modulates DNA-damage-induced p53 response by induction of p53-independent differentiation and apoptosis. 1997 Oncogene pmid:9333015
Kaiser E and Weiss K [Fermentation process during the ensiling of green forage low in nitrate. 2. Fermentation process after supplementation of nitrate, nitrite, lactic acid bacteria and formic acid]. 1997 Arch Tierernahr pmid:9324922
Scannell JP et al. Antimetabolites produced by microorganisms. XIII. The synthesis and microbiological production of a novel amino acid, L-2-amino-4-(2-aminoethoxy) butanoic acid. 1976 J. Antibiot. pmid:931793
Engelhard HH et al. Molecular characterization of glioblastoma cell differentiation. 1997 Neurosurgery pmid:9316051
Dohi H et al. Intake stimulants in perennial ryegrass (Lolium perenne L.) fed to sheep. 1997 J. Dairy Sci. pmid:9313150
Hague A et al. bcl-2 and bak may play a pivotal role in sodium butyrate-induced apoptosis in colonic epithelial cells; however overexpression of bcl-2 does not protect against bak-mediated apoptosis. 1997 Int. J. Cancer pmid:9311611
Ishiguro K and Sartorelli AC Clonal variability in beta-globin mRNA content in an interleukin-3-dependent bone marrow cell line transfected with the erythropoietin receptor before and after stimulation with erythropoietin. 1997 Blood pmid:9310478
Birkett AM et al. Dietary intake and faecal excretion of carbohydrate by Australians: importance of achieving stool weights greater than 150 g to improve faecal markers relevant to colon cancer risk. 1997 Eur J Clin Nutr pmid:9306090
Cuisset L et al. The effects of sodium butyrate on transcription are mediated through activation of a protein phosphatase. 1997 J. Biol. Chem. pmid:9305863
Chénais B et al. Time-course of butyric acid-induced differentiation in human K562 leukemic cell line: rapid increase in gamma-globin, porphobilinogen deaminase and NF-E2 mRNA levels. 1997 Leukemia pmid:9305615
Lewis SJ and Heaton KW Increasing butyrate concentration in the distal colon by accelerating intestinal transit. 1997 Gut pmid:9301506
Ohno Y et al. Macrophage inflammatory protein-2: chromosomal regulation in rat small intestinal epithelial cells. 1997 Proc. Natl. Acad. Sci. U.S.A. pmid:9294201
Talley NA et al. Short-chain fatty acids in the treatment of radiation proctitis: a randomized, double-blind, placebo-controlled, cross-over pilot trial. 1997 Dis. Colon Rectum pmid:9293933
Medina V et al. Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway. 1997 Cancer Res. pmid:9288776
Chen ZJ and Pikaard CS Epigenetic silencing of RNA polymerase I transcription: a role for DNA methylation and histone modification in nucleolar dominance. 1997 Genes Dev. pmid:9284051
Kenyon E et al. Apical and basolateral membrane mechanisms that regulate pHi in bovine retinal pigment epithelium. 1997 Am. J. Physiol. pmid:9277343
De Visser H et al. Nutrient fluxes in splanchnic tissue of dairy cows: influence of grass quality. 1997 J. Dairy Sci. pmid:9276806
Humbert G et al. Method for the measurement of lipase activity in milk. 1997 J. Dairy Res. pmid:9275261
Simon B et al. Transient transcriptional activation of gastrin during sodium butyrate-induced differentiation of islet cells. 1997 Regul. Pept. pmid:9272626
Xiao H et al. Sodium butyrate induces NIH3T3 cells to senescence-like state and enhances promoter activity of p21WAF/CIP1 in p53-independent manner. 1997 Biochem. Biophys. Res. Commun. pmid:9268733
Nakano K et al. Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line. 1997 J. Biol. Chem. pmid:9268365
Tai G et al. Different effects of cyclic AMP and butyrate on eosinophilic differentiation, apoptosis and bcl-2 expression of a human eosinophilic leukemia cell line, EoL-1. 1996 Hematol Oncol pmid:9267464
Navarro JM et al. Differentiation of BCS-TC2 human colon adenocarcinoma cells by sodium butyrate: increase in 5'-nucleotidase activity. 1997 Eur. J. Clin. Invest. pmid:9263751
Qin S and Yamamura H Up-regulation of Syk activity during HL60 cell differentiation into granulocyte but not into monocyte/macrophage-lineage. 1997 Biochem. Biophys. Res. Commun. pmid:9245716
Jacobasch G and Jacobasch KH [Molecular etiology of colorectal carcinogenesis, clinical manifestations and therapy]. 1997 Z Arztl Fortbild Qualitatssich pmid:9244653
Kaeffer B et al. Treatment of rat proximal and distal colonic cells with sodium orthovanadate enhances their adhesion and survival in primary culture. 1997 Cell Biol. Int. pmid:9243806
Siavoshian S et al. Comparison of the effect of different short chain fatty acids on the growth and differentiation of human colonic carcinoma cell lines in vitro. 1997 Cell Biol. Int. pmid:9243803
Ferry AE et al. Globin gene silencing in primary erythroid cultures. An inhibitory role for interleukin-6. 1997 J. Biol. Chem. pmid:9242673
Millais AJ et al. The biotransformation of t-butylacetonitrile and its boron-containing analogue trimethylamine-cyanoborane by Brevibacterium R312. 1997 Arch. Microbiol. pmid:9238109
Erickson KD and Martin JM Early detection of the lytic LMP-1 protein in EBV-infected B-cells suggests its presence in the virion. 1997 Virology pmid:9234942
Atkins KB et al. Stimulation of osteopontin mRNA expression in HL-60 cells is independent of differentiation. 1997 Arch. Biochem. Biophys. pmid:9224725