butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Li Q et al. | Attenuation of glucocorticoid signaling through targeted degradation of p300 via the 26S proteasome pathway. | 2002 | Mol. Endocrinol. | pmid:12456802 |
| Chen T et al. | Histone acetylation is involved in hsp70 gene transcription regulation in Drosophila melanogaster. | 2002 | Arch. Biochem. Biophys. | pmid:12464268 |
| Yu HQ and Fang HH | Acidogenesis of gelatin-rich wastewater in an upflow anaerobic reactor: influence of pH and temperature. | 2003 | Water Res. | pmid:12465788 |
| Rosato RR et al. | The cyclin-dependent kinase inhibitor flavopiridol disrupts sodium butyrate-induced p21WAF1/CIP1 expression and maturation while reciprocally potentiating apoptosis in human leukemia cells. | 2002 | Mol. Cancer Ther. | pmid:12467221 |
| Kurz EU et al. | The histone deacetylase inhibitor sodium butyrate induces DNA topoisomerase II alpha expression and confers hypersensitivity to etoposide in human leukemic cell lines. | 2001 | Mol. Cancer Ther. | pmid:12467229 |
| Scott GK et al. | Transcriptional repression of ErbB2 by histone deacetylase inhibitors detected by a genomically integrated ErbB2 promoter-reporting cell screen. | 2002 | Mol. Cancer Ther. | pmid:12477051 |
| Ohkusa T et al. | Induction of experimental ulcerative colitis by Fusobacterium varium isolated from colonic mucosa of patients with ulcerative colitis. | 2003 | Gut | pmid:12477765 |
| Ruemmele FM et al. | Butyrate induced Caco-2 cell apoptosis is mediated via the mitochondrial pathway. | 2003 | Gut | pmid:12477768 |
| Pryde SE et al. | The microbiology of butyrate formation in the human colon. | 2002 | FEMS Microbiol. Lett. | pmid:12480096 |
| Kennedy C et al. | Cell proliferation in the normal mouse mammary gland and inhibition by phenylbutyrate. | 2002 | Mol. Cancer Ther. | pmid:12481425 |
| Sengupta S et al. | Colonic epithelial atrophy induced by a fibre-free diet in rats is reversed by minimal amounts of luminal butyrate, but only in the short term. | 2002 | ANZ J Surg | pmid:12485223 |
| Bargo F et al. | Ruminal digestion and fermentation of high-producing dairy cows with three different feeding systems combining pasture and total mixed rations. | 2002 | J. Dairy Sci. | pmid:12487462 |
| Rahman E et al. | Antinociceptive activity of Polygonum hydropiper. | 2002 | Fitoterapia | pmid:12490235 |
| Brown AJ et al. | The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. | 2003 | J. Biol. Chem. | pmid:12496283 |
| Rothermund CA et al. | Regulation of Bcl-2 during androgen-unresponsive progression of prostate cancer. | 2002 | Prostate Cancer Prostatic Dis. | pmid:12496988 |
| Finzer P et al. | Growth arrest of HPV-positive cells after histone deacetylase inhibition is independent of E6/E7 oncogene expression. | 2002 | Virology | pmid:12504567 |
| Sugihara A et al. | Purification and characterization of a novel cholesterol esterase from Pseudomonas aeruginosa, with its application to cleaning lipid-stained contact lenses. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12506971 |
| Nankova BB et al. | Nicotinic induction of preproenkephalin and tyrosine hydroxylase gene expression in butyrate-differentiated rat PC12 cells: a model for adaptation to gut-derived environmental signals. | 2003 | Pediatr. Res. | pmid:12508089 |
| Finneran KT et al. | Desulfitobacterium metallireducens sp. nov., an anaerobic bacterium that couples growth to the reduction of metals and humic acids as well as chlorinated compounds. | 2002 | Int. J. Syst. Evol. Microbiol. | pmid:12508850 |
| Duncan SH et al. | Growth requirements and fermentation products of Fusobacterium prausnitzii, and a proposal to reclassify it as Faecalibacterium prausnitzii gen. nov., comb. nov. | 2002 | Int. J. Syst. Evol. Microbiol. | pmid:12508881 |
| Takahashi K et al. | Expression and characterization of frog peptidylglycine alpha-hydroxylating monooxygenase. | 2003 | Protein Expr. Purif. | pmid:12509982 |
| Rahman MM et al. | Two histone deacetylase inhibitors, trichostatin A and sodium butyrate, suppress differentiation into osteoclasts but not into macrophages. | 2003 | Blood | pmid:12511413 |
| Böcker U et al. | Butyrate modulates intestinal epithelial cell-mediated neutrophil migration. | 2003 | Clin. Exp. Immunol. | pmid:12519386 |
| Janda WM et al. | Evaluation of the BactiCard Neisseria for identification of pathogenic Neisseria species and Moraxella catarrhalis. | 2002 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:12525923 |
| Sonoyama K et al. | Upregulation of activin A gene by butyrate in human colon cancer cell lines. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12540370 |
| Chen ZY et al. | [Determination of organic acids in cigarette smoke]. | 2001 | Se Pu | pmid:12545508 |
| van de Mark K et al. | Alpha-lipoic acid induces p27Kip-dependent cell cycle arrest in non-transformed cell lines and apoptosis in tumor cell lines. | 2003 | J. Cell. Physiol. | pmid:12548552 |
| Schubert MA and Müller-Goymann CC | Solvent injection as a new approach for manufacturing lipid nanoparticles--evaluation of the method and process parameters. | 2003 | Eur J Pharm Biopharm | pmid:12551713 |
| Zgouras D et al. | Butyrate impairs intestinal tumor cell-induced angiogenesis by inhibiting HIF-1alpha nuclear translocation. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12559948 |
| Boutillier AL et al. | Selective E2F-dependent gene transcription is controlled by histone deacetylase activity during neuronal apoptosis. | 2003 | J. Neurochem. | pmid:12562525 |
| Burger BV et al. | Semiochemicals of the Scarabaeinae. VII: Identification and synthesis of EAD-active constituents of abdominal sex attracting secretion of the male dung beetle, Kheper subaeneus. | 2002 | J. Chem. Ecol. | pmid:12564798 |
| Majdoub L et al. | Intraruminal propionate supplementation modifies hindlimb energy metabolism without changing the splanchnic release of glucose in growing lambs. | 2003 | Br. J. Nutr. | pmid:12568663 |
| Tsurutani J et al. | Antiproliferative effects of the histone deacetylase inhibitor FR901228 on small-cell lung cancer lines and drug-resistant sublines. | 2003 | Int. J. Cancer | pmid:12569581 |
| Wu Z and Yang ST | Extractive fermentation for butyric acid production from glucose by Clostridium tyrobutyricum. | 2003 | Biotechnol. Bioeng. | pmid:12569628 |
| Andoh A et al. | Role of dietary fiber and short-chain fatty acids in the colon. | 2003 | Curr. Pharm. Des. | pmid:12570825 |
| Carro MD and Ranilla MJ | Effect of the addition of malate on in vitro rumen fermentation of cereal grains. | 2003 | Br. J. Nutr. | pmid:12575902 |
| Svechnikova I et al. | Apoptosis and tumor remission in liver tumor xenografts by 4-phenylbutyrate. | 2003 | Int. J. Oncol. | pmid:12579311 |
| Alves GL and Franco MR | Headspace gas chromatography-mass spectrometry of volatile compounds in murici (Byrsonima crassifolia l. Rich). | 2003 | J Chromatogr A | pmid:12580497 |
| Shamala TR et al. | Identification of polyhydroxyalkanoate (PHA)-producing Bacillus spp. using the polymerase chain reaction (PCR). | 2003 | J. Appl. Microbiol. | pmid:12588544 |
| Rabelo FL et al. | Apoptosis induced by butyrate is independent of Jak/STAT signaling in a fibrosarcoma cell line. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12589807 |
| Gallert C et al. | Scale-up of anaerobic digestion of the biowaste fraction from domestic wastes. | 2003 | Water Res. | pmid:12598207 |
| Buxton DB et al. | Induction of nonmuscle myosin heavy chain II-C by butyrate in RAW 264.7 mouse macrophages. | 2003 | J. Biol. Chem. | pmid:12598534 |
| Hinnebusch BF et al. | Transcriptional activation of the enterocyte differentiation marker intestinal alkaline phosphatase is associated with changes in the acetylation state of histone H3 at a specific site within its promoter region in vitro. | 2003 | J. Gastrointest. Surg. | pmid:12600448 |
| Courtois F et al. | Membrane peroxidation by lipopolysaccharide and iron-ascorbate adversely affects Caco-2 cell function: beneficial role of butyric acid. | 2003 | Am. J. Clin. Nutr. | pmid:12600871 |
| Van Dyk DD et al. | Identification of cellular changes associated with increased production of human growth hormone in a recombinant Chinese hamster ovary cell line. | 2003 | Proteomics | pmid:12601807 |
| Vozza A et al. | New established melanoma cell lines: genetic and biochemical characterization of cell division cycle. | 2003 | J Eur Acad Dermatol Venereol | pmid:12602966 |
| Suzuki M et al. | Interleukin-1beta converting enzyme subfamily inhibitors prevent induction of CD86 molecules by butyrate through a CREB-dependent mechanism in HL60 cells. | 2003 | Immunology | pmid:12603604 |
| Qiu YL et al. | Sporotomaculum syntrophicum sp. nov., a novel anaerobic, syntrophic benzoate-degrading bacterium isolated from methanogenic sludge treating wastewater from terephthalate manufacturing. | 2003 | Arch. Microbiol. | pmid:12605290 |
| Schweigel M and Martens H | Anion-dependent Mg2+ influx and a role for a vacuolar H+-ATPase in sheep ruminal epithelial cells. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12606303 |
| Collins YF et al. | Evidence of a relationship between autolysis of starter bacteria and lipolysis in cheddar cheese during ripening. | 2003 | J. Dairy Res. | pmid:12617399 |
| Lütke-Eversloh T et al. | Biosynthesis of novel thermoplastic polythioesters by engineered Escherichia coli. | 2002 | Nat Mater | pmid:12618785 |
| McMillan L et al. | Opposing effects of butyrate and bile acids on apoptosis of human colon adenoma cells: differential activation of PKC and MAP kinases. | 2003 | Br. J. Cancer | pmid:12618885 |
| Ozbun LL et al. | Differentially expressed nucleolar TGF-beta1 target (DENTT) in mouse development. | 2003 | Dev. Dyn. | pmid:12619135 |
| Gururaj AE et al. | Antiangiogenic effects of butyric acid involve inhibition of VEGF/KDR gene expression and endothelial cell proliferation. | 2003 | Mol. Cell. Biochem. | pmid:12619895 |
| Sawa H et al. | Histone deacetylase inhibitors such as sodium butyrate and trichostatin A inhibit vascular endothelial growth factor (VEGF) secretion from human glioblastoma cells. | 2002 | Brain Tumor Pathol | pmid:12622137 |
| Bai L et al. | Regulation of epithelial cell growth by ZBP-89: potential relevance in pancreatic cancer. | 2002 | Int J Gastrointest Cancer | pmid:12622418 |
| Henningsson AM et al. | Influences of dietary adaptation and source of resistant starch on short-chain fatty acids in the hindgut of rats. | 2003 | Br. J. Nutr. | pmid:12628027 |
| Gerhäuser C et al. | Mechanism-based in vitro screening of potential cancer chemopreventive agents. | 2003 Feb-Mar | Mutat. Res. | pmid:12628514 |
| Fang HY et al. | Cyclooxygenase-2 in human non-small cell lung cancer. | 2003 | Eur J Surg Oncol | pmid:12633561 |
| Ueda M et al. | Up-regulation of the peroxisomal beta-oxidation system occurs in butyrate-grown Candida tropicalis following disruption of the gene encoding peroxisomal 3-ketoacyl-CoA thiolase. | 2003 | Biochim. Biophys. Acta | pmid:12633682 |
| Venkatraman A et al. | Amelioration of dextran sulfate colitis by butyrate: role of heat shock protein 70 and NF-kappaB. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12637250 |
| Cremin JD et al. | Glucose alleviates ammonia-induced inhibition of short-chain fatty acid metabolism in rat colonic epithelial cells. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12637251 |
| Shao Y and Marriott P | Separation of positional isomers by the use of coupled shape-selective stationary phase columns. | 2003 | Anal Bioanal Chem | pmid:12638047 |
| Kanauchi O et al. | Germinated barley foodstuff, a prebiotic product, ameliorates inflammation of colitis through modulation of the enteric environment. | 2003 | J. Gastroenterol. | pmid:12640526 |
| Vernia P et al. | Topical butyrate improves efficacy of 5-ASA in refractory distal ulcerative colitis: results of a multicentre trial. | 2003 | Eur. J. Clin. Invest. | pmid:12641543 |
| Skarpidi E et al. | Hydroxamide derivatives of short-chain fatty acids are potent inducers of human fetal globin gene expression. | 2003 | Exp. Hematol. | pmid:12644016 |
| KovarÃková P et al. | Photochemical stability of nimesulide. | 2003 | J Pharm Biomed Anal | pmid:12644210 |
| Shi W et al. | Induction of a senescent-like phenotype does not confer the ability of bovine immortal cells to support the development of nuclear transfer embryos. | 2003 | Biol. Reprod. | pmid:12646489 |
| Sutton JD et al. | Effect of method of application of a fibrolytic enzyme product on digestive processes and milk production in Holstein-Friesian cows. | 2003 | J. Dairy Sci. | pmid:12647961 |
| Rouf AS et al. | Evaluation of antidiarrhoeal activity Rumex maritimus root. | 2003 | J Ethnopharmacol | pmid:12648830 |
| Chernova MN et al. | Acute regulation of the SLC26A3 congenital chloride diarrhoea anion exchanger (DRA) expressed in Xenopus oocytes. | 2003 | J. Physiol. (Lond.) | pmid:12651923 |
| Karlsson S et al. | Expression of Clostridium difficile toxins A and B and their sigma factor TcdD is controlled by temperature. | 2003 | Infect. Immun. | pmid:12654792 |
| Tabuchi Y et al. | Development of a conditionally immortalized testicular Sertoli cell line RTS3-3 from adult transgenic rats harboring temperature-sensitive simian virus 40 large T-antigen gene. | 2003 | Cell Struct. Funct. | pmid:12655154 |
| Kopecný J et al. | Butyrivibrio hungatei sp. nov. and Pseudobutyrivibrio xylanivorans sp. nov., butyrate-producing bacteria from the rumen. | 2003 | Int. J. Syst. Evol. Microbiol. | pmid:12656174 |
| Collard TJ et al. | Transcriptional upregulation of the insulin-like growth factor binding protein IGFBP-3 by sodium butyrate increases IGF-independent apoptosis in human colonic adenoma-derived epithelial cells. | 2003 | Carcinogenesis | pmid:12663497 |
| Carbone V et al. | Structure-based design of inhibitors of human L-xylulose reductase modelled into the active site of the enzyme. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12668014 |
| Finzer P et al. | Phenylbutyrate inhibits growth of cervical carcinoma cells independent of HPV type and copy number. | 2003 | J. Cancer Res. Clin. Oncol. | pmid:12669235 |
| Rabelo FL et al. | Inhibition of ERK1/2 and CREB phosphorylation by caspase-dependent mechanism enhances apoptosis in a fibrosarcoma cell line treated with butyrate. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12670506 |
| Hangen L and Bennink MR | Consumption of black beans and navy beans (Phaseolus vulgaris) reduced azoxymethane-induced colon cancer in rats. | 2002 | Nutr Cancer | pmid:12672642 |
| Yamazaki Y et al. | HIF-1-dependent VEGF reporter gene assay by a stable transformant of CHO cells. | 2003 | Biol. Pharm. Bull. | pmid:12673017 |
| Zhu Y and Yang ST | Adaptation of Clostridium tyrobutyricum for enhanced tolerance to butyric acid in a fibrous-bed bioreactor. | 2003 Mar-Apr | Biotechnol. Prog. | pmid:12675573 |
| Hu YC et al. | Enhancement and prolongation of baculovirus-mediated expression in mammalian cells: focuses on strategic infection and feeding. | Biotechnol. Prog. | pmid:12675574 | |
| Chin HL et al. | Fedbatch operation using Clostridium acetobutylicum suspension culture as biocatalyst for enhancing hydrogen production. | Biotechnol. Prog. | pmid:12675576 | |
| Yan J and Xu YH | Tributyrin inhibits human gastric cancer SGC-7901 cell growth by inducing apoptosis and DNA synthesis arrest. | 2003 | World J. Gastroenterol. | pmid:12679905 |
| Nilsson NE et al. | Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12684041 |
| Buda A et al. | Butyrate downregulates alpha2beta1 integrin: a possible role in the induction of apoptosis in colorectal cancer cell lines. | 2003 | Gut | pmid:12692060 |
| Schauber J et al. | Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways. | 2003 | Gut | pmid:12692061 |
| Leisy DJ et al. | Transduction of cultured fish cells with recombinant baculoviruses. | 2003 | J. Gen. Virol. | pmid:12692282 |
| Rambhatla L et al. | Generation of hepatocyte-like cells from human embryonic stem cells. | 2003 | Cell Transplant | pmid:12693659 |
| Lee SC et al. | Activation of terminal B cell differentiation by inhibition of histone deacetylation. | 2003 | Mol. Immunol. | pmid:12695118 |
| Walker TS et al. | Metabolic profiling of root exudates of Arabidopsis thaliana. | 2003 | J. Agric. Food Chem. | pmid:12696935 |
| Cao X et al. | Aberrant regulation of human intestinal proglucagon gene expression in the NCI-H716 cell line. | 2003 | Endocrinology | pmid:12697711 |
| Sheridan BA et al. | Biofiltration of n-butyric acid for the control of odour. | 2003 | Bioresour. Technol. | pmid:12699941 |
| Pind PF et al. | Dynamics of the anaerobic process: effects of volatile fatty acids. | 2003 | Biotechnol. Bioeng. | pmid:12701145 |
| Tóth M et al. | Identification of pheromones and optimization of bait composition for click beetle pests (Coleoptera: Elateridae) in Central and Western Europe. | 2003 | Pest Manag. Sci. | pmid:12701702 |
| McCarter JP et al. | Analysis and functional classification of transcripts from the nematode Meloidogyne incognita. | 2003 | Genome Biol. | pmid:12702207 |
| Baloch MI and Akunna JC | Effect of rapid hydraulic shock loads on the performance of granular bed baffled reactor. | 2003 | Environ Technol | pmid:12703861 |
| Zhang WF et al. | Effects of isomalto-oligosaccharides on broiler performance and intestinal microflora. | 2003 | Poult. Sci. | pmid:12710488 |
| Le Poul E et al. | Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. | 2003 | J. Biol. Chem. | pmid:12711604 |
| Nkondjock A et al. | Assessment of risk associated with specific fatty acids and colorectal cancer among French-Canadians in Montreal: a case-control study. | 2003 | Int J Epidemiol | pmid:12714537 |