butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Dehpour AR et al. | In vitro binding of dantrolene to sarcoplasmic reticulum of rabbit skeletal muscle. | 1982 | Biochem. Pharmacol. | pmid:7082378 |
Reczek PR et al. | Sodium butyrate induced structural changes in HeLa cell chromatin. | 1982 | Biochemistry | pmid:7074068 |
Roediger WE et al. | Luminal ions and short chain fatty acids as markers of functional activity of the mucosa in ulcerative colitis. | 1982 | J. Clin. Pathol. | pmid:7068924 |
Soergel KH et al. | N-butyrate absorption in the human colon. | 1982 | Dig. Dis. Sci. | pmid:7067579 |
Edde B et al. | Changes in some cytoskeletal proteins during neuroblastoma cell differentiation. | 1982 | Biochimie | pmid:7066411 |
Cousens LS and Alberts BM | Accessibility of newly synthesized chromatin to histone acetylase. | 1982 | J. Biol. Chem. | pmid:7061519 |
Vavra KJ et al. | Regulation of histone acetylation in Tetrahymena macro- and micronuclei. | 1982 | J. Biol. Chem. | pmid:7061439 |
Mironescu SG et al. | Cyclic nucleotide modulation of in vitro morphological transformation of Syrian hamster cells. | 1982 | Cancer Res. | pmid:7060004 |
Tsao D et al. | Differential effects of sodium butyrate, dimethyl sulfoxide, and retinoic acid on membrane-associated antigen, enzymes, and glycoproteins of human rectal adenocarcinoma cells. | 1982 | Cancer Res. | pmid:7059970 |
O'Donnell ME and Horwitz BA | Effects of butyrate on ouabain-sensitive respiration of hamster brown adipocytes. | 1982 | Am. J. Physiol. | pmid:7058878 |
Takahara N et al. | Induction of alkaline phosphatase activity in cultured human intracranial tumor cells. | 1982 | Cancer Res. | pmid:7055804 |
Roediger WE and Rae DA | Trophic effect of short chain fatty acids on mucosal handling of ions by the defunctioned colon. | 1982 | Br J Surg | pmid:7053797 |
Refojo MF | Current status of biomaterials in ophthalmology. | 1982 Mar-Apr | Surv Ophthalmol | pmid:7046116 |
Dokhelar MC et al. | NK cell sensitivity of the leukemic K 562 cells; effect of sodium butyrate and hemin induction. | 1982 | J. Immunol. | pmid:7033373 |
Oberley TD et al. | The growth of primary glomerular cells as a confluent monolayer in a chemically defined serum-free medium: specific requirements for prostaglandins and extracellular matrix molecules. | 1981 | Am. J. Pathol. | pmid:7020428 |
Dodds PF et al. | Acetoacetyl-CoA reductase activity of lactating bovine mammary fatty acid synthase. | 1981 | J. Biol. Chem. | pmid:7016867 |
Chaussain JL et al. | Serum branched-chain amino acids in the diagnosis of hyperinsulinism in infancy. | 1980 | J. Pediatr. | pmid:7003083 |
Dahmann G et al. | Influence of the phenylalanine dose on the aromatic acid excretion in phenylketonuric heterozygotes and controls after oral loading. | 1978 | Eur. J. Pediatr. | pmid:699924 |
Becker A and Hoffmeister RT | Fenbufen, a new non-steroidal anti-inflammatory agent in rheumatoid arthritis, its efficacy and toxicity. | 1980 | J. Int. Med. Res. | pmid:6998793 |
Külpmann WR | [A gas-chromatographic method for the determination of carbamazepine, phenobarbital, phenytoin and primidone in the same extract of serum (author's transl)]. | 1980 | J. Clin. Chem. Clin. Biochem. | pmid:6991632 |
Azer PC et al. | Ectopic production of pregnancy-specific beta 1-glycoprotein by a nontrophoblastic tumor in vitro. | 1980 | J. Clin. Endocrinol. Metab. | pmid:6986392 |
Nicolay K et al. | Carbon-13 nuclear magnetic resonance studies of acetate metabolism in intact cells of rhodopseudomonas sphaeroides. | 1982 | Biochim. Biophys. Acta | pmid:6980672 |
Breitman TR and Gallo RC | New facts and speculations on human myeloid leukemias. | 1981 | Blood Cells | pmid:6964818 |
Mason RJ et al. | Transepithelial transport by pulmonary alveolar type II cells in primary culture. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6964398 |
Ekblom M et al. | Acute erythroleukaemia with L3 morphology and the 14q+ chromosome. | 1982 | Scand J Haematol | pmid:6956958 |
Yancheva NY and Djondjurov LP | Differentiation of Friend erythroleukemic cells in media lacking fetal calf serum. | 1981 | Neoplasma | pmid:6951111 |
Covault J et al. | Histone hypoacetylation following release of HTC cells from butyrate. | 1982 | J. Biol. Chem. | pmid:6950936 |
Wintersberg E and Mudrak I | Butyrate does not induce single strand breaks in Friend erythroleukemia cells or in 3T6 mouse fibroblasts. | 1982 | FEBS Lett. | pmid:6950907 |
Okano H et al. | Human erythroid cell lines derived from a patient with acute erythremia. | 1981 | J. Cancer Res. Clin. Oncol. | pmid:6949905 |
Vainchenker W et al. | Heterogeneity in the cellular commitment of a human leukemic cell line: K 562. | 1981 | Blood Cells | pmid:6945884 |
Zucker RM | Cell cycle dependency of tumor promoter on murine erythroleukemic cells. | 1981 | Cytometry | pmid:6944181 |
Ko LW and Koestner A | Morphologic and morphometric analyses of butyrate-induced alterations of rat glioma cells in vitro. | 1980 | J. Natl. Cancer Inst. | pmid:6933237 |
Goz B et al. | Inhibition by deoxycytidine, cytidine, and beta-cytosine arabinoside of the induction of alkaline phosphatase activity in HeLa cells. | 1980 | J. Natl. Cancer Inst. | pmid:6929374 |
Rao PN et al. | Rhodium (II) butyrate: a potential anticancer drug with cell cycle phase-specific effects in HeLa cells. | 1980 | J. Natl. Cancer Inst. | pmid:6929001 |
Leibovitch MP et al. | Effect of sodium butyrate on messenger RNA populations in myogenic cells in culture. | 1982 | Differentiation | pmid:6897049 |
Joseph G et al. | Histones from Chinese hamster ovary cells. Multiple modified forms: a quantitative approach. | 1983 | Eur. J. Biochem. | pmid:6884354 |
Bide RW and Dorward WJ | Excess rumen product anions in cattle. II. Toxic and lethal effects with butyrate. | 1983 | Can. J. Comp. Med. | pmid:6883190 |
Bide RW | Excess rumen product anions in cattle. I. Blood clearance rates and reduced liver function from sublethal doses of volatile fatty acids, lactate and succinate. | 1983 | Can. J. Comp. Med. | pmid:6883189 |
Snow TR and Caspar T | Substrate dependence of myocardial response to hypoxia in the presence of theophylline. | 1983 | Am. J. Physiol. | pmid:6881369 |
Omura S et al. | Valine as a precursor of n-butyrate unit in the biosynthesis of macrolide aglycone. | 1983 | J. Antibiot. | pmid:6874580 |
Yukioka M et al. | Transcribing chromatin is not preferentially enriched with acetylated histones. | 1983 | FEBS Lett. | pmid:6873281 |
Prasad MR et al. | Kinetic evidence for two separate trans-2-enoyl CoA reductases in rat hepatic microsomes: NADPH-specific short chain- and NAD(P)H-dependent long chain-reductase. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6870879 |
Werkmeister JA et al. | Modulation of K562 cells with sodium butyrate. Association of impaired NK susceptibility with sialic acid and analysis of other parameters. | 1983 | Int. J. Cancer | pmid:6862694 |
Sullivan SG et al. | Effects of prednisolone and butyrate on agglutinability of HeLa cells by concanavalin A. | 1983 | Experientia | pmid:6861973 |
Garson D et al. | Protective effects of differentiation inducers on natural killer sensitivity of K 562 cells: Analysis at a single-cell level. | 1983 | Cell. Immunol. | pmid:6861208 |
Hanford WC and Fishman WH | Measurement of biosynthetic rates and intracellular transit times for a cell-surface membrane glycoprotein, alkaline phosphatase in HeLa cells. | 1983 | Anal. Biochem. | pmid:6859522 |
Rhead WJ et al. | Dicarboxylic aciduria: deficient [1-14C]octanoate oxidation and medium-chain acyl-CoA dehydrogenase in fibroblasts. | 1983 | Science | pmid:6857268 |
Pashev IG et al. | Histone acetylation in chromatin containing mouse satellite DNA. | 1983 | Eur. J. Biochem. | pmid:6852048 |
Gambari R et al. | Desferrioxamine inhibits induced erythroid differentiation of human leukemic K-562 cells. | 1983 | Cell Differ. | pmid:6850836 |
Demaugre F et al. | Role of the mitochondrial metabolism of pyruvate on the regulation of ketogenesis in rat hepatocytes. | 1983 | Metab. Clin. Exp. | pmid:6848896 |
Tokumitsu S and Fishman WH | Alkaline phosphatase biosynthesis in the endoplasmic reticulum and its transport through the Golgi apparatus to the plasma membrane: cytochemical evidence. | 1983 | J. Histochem. Cytochem. | pmid:6841969 |
Gröbner P and Loidl P | Response of the dTMP-synthesizing enzymes to differentiation processes in Physarum polycephalum. | 1983 | Exp. Cell Res. | pmid:6840218 |
Morrow JS et al. | Butyrate regulates glycosylation of the glycoprotein hormone alpha subunit secreted by "glucose-starved" human liver cells. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6838600 |
Hay CW and Candido EP | Histone deacetylase. Association with a nuclease resistant, high molecular weight fraction of HeLa cell chromatin. | 1983 | J. Biol. Chem. | pmid:6833227 |
Dollenmeier P and Eppenberger HM | Modulation of protein synthesis in primary myogenic cells from chicken by cultivation in the serum-free, hormonally defined medium 'DMN'. | 1983 | Experientia | pmid:6832306 |
Herz F and Halwer M | Preferential alkaline phosphatase isoenzyme induction by sodium butyrate. | 1983 | Biochim. Biophys. Acta | pmid:6830876 |
Wick MR et al. | Cutaneous malignant histiocytosis: a clinical and histopathologic study of eight cases, with immunohistochemical analysis. | 1983 | J. Am. Acad. Dermatol. | pmid:6826808 |
Bauer G | Induction of Epstein-Barr virus early antigens by corticosteroids: inhibition by TPA and retinoic acid. | 1983 | Int. J. Cancer | pmid:6826253 |
Lough J | Modulation of in vitro myogenesis by submillimolar concentrations of sodium butyrate. | 1983 | Cell Differ. | pmid:6825176 |
Tsao D et al. | Effect of sodium butyrate on carcinoembryonic antigen production by human colonic adenocarcinoma cells in culture. | 1983 | Cancer Res. | pmid:6825092 |
Iseki S and Baserga R | Effect of butyrate on adenovirus infection in semipermissive cells. | 1983 | Virology | pmid:6823744 |
Whitlock JP et al. | Acetylation and calcium-dependent phosphorylation of histone H3 in nuclei from butyrate-treated HeLa cells. | 1983 | J. Biol. Chem. | pmid:6822500 |
Cox GS and McClure DS | Effect of media composition on the induction of chorionic gonadotropin by sodium butyrate in HeLa cells. | 1983 | In Vitro | pmid:6822399 |
Horton MA | Analysis of marker enzymes in the K562 erythroleukaemia cell line: no coordinate expression of red cell enzymes on induction of haemoglobin synthesis. | 1982 | Biomed. Pharmacother. | pmid:6819869 |
Reuter G et al. | Butyrate sensitive suppressor of position-effect variegation mutations in Drosophila melanogaster. | 1982 | Mol. Gen. Genet. | pmid:6819429 |
Nakao Y et al. | Paradoxical anti-leukemic effects of plant-derived tumor promoters on a human thymic lymphoblast cell line. | 1982 | Int. J. Cancer | pmid:6819241 |
Boffi V and Lucarelli AM | Effect of the carbon oxidation level of the energy source on heat of reaction in biosynthesis of a Pseudomonas strain. | 1982 | Microbiologica | pmid:6818430 |
Cinti DL et al. | Evidence for a second microsomal trans-2-enoyl coenzyme A reductase in rat liver. NADPH-specific short chain reductase. | 1982 | J. Biol. Chem. | pmid:6815194 |
Poirier O et al. | [Enhancement by sodium butyrate of the cytotoxic effect of methotrexate on leukemic cells]. | 1982 | C R Seances Acad Sci III | pmid:6812884 |
Koshihara Y et al. | Enhancement of 5-lipoxygenase activity in mastocytoma P-815 cells by n-butyrate treatment. | 1982 | J. Biol. Chem. | pmid:6806271 |
Gálfi P et al. | Effect of sodium n-butyrate on primary ruminal epithelial cell culture. | 1981 | Zentralbl Veterinarmed A | pmid:6792837 |
Koshihara Y et al. | Induction of prostacyclin formation by sodium n-butyrate in a cloned epithelial liver cell line. | 1981 | Biochim. Biophys. Acta | pmid:6788091 |
Boudreaux DP et al. | Biochemical and genetic characterization of an auxotroph of Bacillus subtilis altered in the Acyl-CoA:acyl-carrier-protein transacylase. | 1981 | Eur. J. Biochem. | pmid:6785086 |
Fallon RJ et al. | Morphologic and biosynthetic modulations of HeLa cells mediated by sodium butyrate. | 1980 | Birth Defects Orig. Artic. Ser. | pmid:6783146 |
Roberts CM et al. | The role of enoyl-coa hydratase in the metabolism of isoleucine by Pseudomonas putida. | 1978 | Arch. Microbiol. | pmid:678016 |
Kawamura M et al. | Enhancement of prostaglandin synthesizing activity by the treatment with sodium n-butyrate on cloned mastocytoma cells and various other tissue cell lines. | 1980 | Prostaglandins | pmid:6775349 |
Weingarten D and de Vellis J | Selective inhibition by sodium butyrate of the glucocorticoid induction of glycerol phosphate dehydrogenase in glial cultures. | 1980 | Biochem. Biophys. Res. Commun. | pmid:6772178 |
Forster J et al. | Organic substrate effects on and heterogeneity of Necturus proximal tubule function. | 1980 | Kidney Int. | pmid:6771454 |
Snow TR | Effect of substrates on the mechanical performance of rhesus monkey papillary muscle. | 1980 | Experientia | pmid:6769694 |
Mori Y et al. | Effect of sodium butyrate on the production of serotonin, histamine and glycosaminoglycans by cultured murine mastocytoma cells. | 1980 | Exp. Cell Res. | pmid:6769688 |
Koshihara Y et al. | Sodium n-butyrate induces prostaglandin synthetase activity in mastocytoma P-815 cells. | 1980 | Biochim. Biophys. Acta | pmid:6768397 |
Nakamura N et al. | Changes in the cellular glycosaminoglycans of cultured mastocytoma cells induced by sodium butyrate. | 1980 | Biochim. Biophys. Acta | pmid:6766327 |
Mochizuki M et al. | Synthesis and mutagenicity of 4-(N-butylnitrosamino)-4-hydroxybutyric acid lactone, a possible activated metabolite of the proximate bladder carcinogen N-butyl-N-(3-carboxypropyl)nitrosamine. | 1980 | Cancer Res. | pmid:6765916 |
Sasaki Y et al. | Effects of cold exposure on insulin and glucagon secretion in sheep. | 1982 | Endocrinology | pmid:6754353 |
Testa U et al. | Regulation of i- and I-antigen expression in the K562 cell line. | 1982 | Cancer Res. | pmid:6751526 |
Dennis MV et al. | Secreted glycoproteins of human kidney tumour cells contain sulphated complex-type oligosaccharides. | 1984 | J. Cell. Sci. | pmid:6746767 |
Augeron C and Laboisse CL | Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate. | 1984 | Cancer Res. | pmid:6744312 |
Vömel T et al. | [Phagocytic activity of isolated perfused liver of rats of different ages. Biochemical and structural studies following perfusion with Cu-ceruloplasmin]. | 1984 Mar-Apr | Z Gerontol | pmid:6730634 |
Gullans SR et al. | Glucose-dependent respiration in suspensions of rabbit cortical tubules. | 1984 | J. Membr. Biol. | pmid:6726793 |
Abe M and Kurihara Y | Long-term cultivation of certain rumen protozoa in a continuous fermentation system supplemented with sponge materials. | 1984 | J. Appl. Bacteriol. | pmid:6725158 |
Hartrampf G and Buckel W | The stereochemistry of the formation of the methyl group in the glutamate mutase-catalysed reaction in Clostridium tetanomorphum. | 1984 | FEBS Lett. | pmid:6723977 |
Threadgill GJ and Arnstein HR | The nonhistone proteins of developing mammalian erythroid cells. | 1984 | Cell Differ. | pmid:6722891 |
Otto DA | Relationship of the ATP/ADP ratio to the site of octanoate activation. | 1984 | J. Biol. Chem. | pmid:6715356 |
Siddiqui B and Kim YS | Effects of sodium butyrate, dimethyl sulfoxide, and retinoic acid on glycolipids of human rectal adenocarcinoma cells. | 1984 | Cancer Res. | pmid:6704971 |
Marty J and Vernay M | Absorption and metabolism of the volatile fatty acids in the hind-gut of the rabbit. | 1984 | Br. J. Nutr. | pmid:6704374 |
Stevens MS et al. | Associated effects of sodium butyrate on histone acetylation and estrogen receptor in the human breast cancer cell line MCF-7. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6704117 |
Bertrand E et al. | Influence of histone hyperacetylation on nucleosomal particles as visualized by electron microscopy. | 1984 | Arch. Biochem. Biophys. | pmid:6703701 |
Nozawa S et al. | [Modulation of alkaline phosphatase by butyrate and prednisolone in uterine cervical cancer cell line (SKG-III)]. | 1984 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:6699450 |
Ito F and Chou JY | Induction of placental alkaline phosphatase biosynthesis by sodium butyrate. | 1984 | J. Biol. Chem. | pmid:6698979 |
Dexter DL et al. | Sodium butyrate-induced alteration of growth properties and glycogen levels in cultured human colon carcinoma cells. | 1984 | Histochem. J. | pmid:6698802 |