butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Haag MM et al. | Reverse transformation and genome exposure in the C6 glial tumor cell line. | 1994 | Cancer Invest. | pmid:8281464 |
Fürll M et al. | [Effect of a three-week butyric acid exposure on the mineral metabolism and the skeletal system in cattle]. | 1993 | Berl. Munch. Tierarztl. Wochenschr. | pmid:8267564 |
Fürll M et al. | [Hormonal reactions in fattening bulls and cows during a three-week butyric acid exposure]. | 1993 | Berl. Munch. Tierarztl. Wochenschr. | pmid:8267563 |
Stark AH and Madar Z | In vitro production of short-chain fatty acids by bacterial fermentation of dietary fiber compared with effects of those fibers on hepatic sterol synthesis in rats. | 1993 | J. Nutr. | pmid:8263612 |
Karuri AR et al. | Selective cellular acidification and toxicity of weak organic acids in an acidic microenvironment. | 1993 | Br. J. Cancer | pmid:8260358 |
Perry CA et al. | Parental nucleosomes segregated to newly replicated chromatin are underacetylated relative to those assembled de novo. | 1993 | Biochemistry | pmid:8257695 |
Planchon P et al. | Differential elimination of synthetic butyric triglycerides in vivo: a pharmacokinetic study. | 1993 | J Pharm Sci | pmid:8254490 |
Halvorsen YD et al. | Vasodilation of rat retinal microvessels induced by monobutyrin. Dysregulation in diabetes. | 1993 | J. Clin. Invest. | pmid:8254042 |
Roediger WE | Colonic epithelial metabolism in ulcerative colitis. | 1993 | Gut | pmid:8244158 |
Finnie IA et al. | Ileal and colonic epithelial metabolism in quiescent ulcerative colitis: increased glutamine metabolism in distal colon but no defect in butyrate metabolism. | 1993 | Gut | pmid:8244143 |
Piñeiro M et al. | Transcription of mononucleosomal particles acetylated in the presence of n-butyrate. | 1993 | Mol. Biol. Rep. | pmid:8232292 |
Dimitrov S et al. | Chromatin transitions during early Xenopus embryogenesis: changes in histone H4 acetylation and in linker histone type. | 1993 | Dev. Biol. | pmid:8224538 |
Musk SR and Johnson IT | Allyl isothiocyanate is selectively toxic to transformed cells of the human colorectal tumour line HT29. | 1993 | Carcinogenesis | pmid:8222057 |
Gope R and Gope ML | Effect of sodium butyrate on the expression of retinoblastoma (RB1) and P53 gene and phosphorylation of retinoblastoma protein in human colon tumor cell line HT29. | 1993 | Cell. Mol. Biol. (Noisy-le-grand) | pmid:8220069 |
Nakai T et al. | Changes in CA125 release and surface expression caused by drugs in uterine cervix adenocarcinoma cells. | 1993 | Ann Nucl Med | pmid:8217487 |
Gürtler H et al. | Acute metabolic and hormonal effects of intravenously administered sodium n-butyrate in untreated and alloxan-diabetic sheep. | 1993 | Zentralbl Veterinarmed A | pmid:8212952 |
Cairns SP and Dulhunty AF | Beta-adrenoceptor activation shows high-frequency fatigue in skeletal muscle fibers of the rat. | 1994 | Am. J. Physiol. | pmid:8203484 |
Sheikh MS et al. | Expression of estrogen receptors in estrogen receptor-negative human breast carcinoma cells: modulation of epidermal growth factor-receptor (EGF-R) and transforming growth factor alpha (TGF alpha) gene expression. | 1994 | J. Cell. Biochem. | pmid:8200909 |
Barratt MJ et al. | Mitogen-stimulated phosphorylation of histone H3 is targeted to a small hyperacetylation-sensitive fraction. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8197135 |
Ogryzko VV et al. | Dissociation of retinoblastoma gene protein hyperphosphorylation and commitment to enter S phase. | 1994 | J. Virol. | pmid:8189510 |
Goh SH et al. | Inhibition of tumour promotion by various palm-oil tocotrienols. | 1994 | Int. J. Cancer | pmid:8181855 |
Ghibelli L et al. | A protein produced by a monocytic human cell line can induce apoptosis on tumor cells. | 1994 | FEBS Lett. | pmid:8181560 |
Duman RS et al. | Induction of beta 2-adrenergic receptor mRNA and ligand binding in HeLa cells. | 1994 | J. Recept. Res. | pmid:8158578 |
Schlake T et al. | Gene expression within a chromatin domain: the role of core histone hyperacetylation. | 1994 | Biochemistry | pmid:8155635 |
Higgins PJ and Lipkin M | Expression of plasminogen activator inhibitor type 1 (PAI-1) by HT-29di human large bowel carcinoma cells is modulated as a function of epithelial differentiation. | 1994 | Cancer Lett. | pmid:8149346 |
Boffa LC et al. | Selective hypermethylation of transcribed nucleosomal DNA by sodium butyrate. | 1994 | Exp. Cell Res. | pmid:8143791 |
Honda J et al. | Spectroscopic observation of the intramolecular electron transfer in the photoactivation processes of nitrile hydratase. | 1994 | Biochemistry | pmid:8142355 |
Lee S et al. | 1,25-Dihydroxyvitamin D3 and pancreatic beta-cell function: vitamin D receptors, gene expression, and insulin secretion. | 1994 | Endocrinology | pmid:8137721 |
Morand C et al. | Importance of the modulation of glycolysis in the control of lactate metabolism by fatty acids in isolated hepatocytes from fed rats. | 1994 | Arch. Biochem. Biophys. | pmid:8135535 |
Cann IK et al. | Effects of 3 chemical treatments on in vitro fermentation of rice straw by mixed rumen microbes in the presence or absence of anaerobic rumen fungi. | 1994 | Reprod. Nutr. Dev. | pmid:8129842 |
Fedotov VP et al. | [The possible participation of gap junctions in the realization of the effects of stimulators of secretory processes in the hypophysis]. | 1993 | Biull Eksp Biol Med | pmid:8123822 |
Krief S et al. | Transcriptional modulation by n-butyric acid of beta 1-, beta 2-, and beta 3-adrenergic receptor balance in 3T3-F442A adipocytes. | 1994 | J. Biol. Chem. | pmid:8120022 |
Aviram A et al. | Comparison between the effect of butyric acid and its prodrug pivaloyloxymethylbutyrate on histones hyperacetylation in an HL-60 leukemic cell line. | 1994 | Int. J. Cancer | pmid:8119779 |
Horvath PJ et al. | Differential effect of butyrate on lipids of human colon cancer cells. | 1993 | Nutr Cancer | pmid:8108277 |
Frommel TO et al. | Variable effects of sodium butyrate on the expression and function of the MDR1 (P-glycoprotein) gene in colon carcinoma cell lines. | 1993 | Int. J. Cancer | pmid:8103760 |
Reeder JA et al. | Sodium butyrate differentially modulates plasminogen activator inhibitor type-1, urokinase plasminogen activator, and its receptor in a human colon carcinoma cell. | 1993 | Teratog., Carcinog. Mutagen. | pmid:8102211 |
Oster T et al. | Induction of recombinant human gamma-glutamyl transferase by sodium butyrate in transfected V79 and CHO Chinese hamster cells. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8099285 |
VanderMeulen DL et al. | The identification of glioblastoma-associated, fucose-containing glycoproteins induced by retinoic acid. | 1994 Feb-Apr | Mol. Chem. Neuropathol. | pmid:8086041 |
Illg DJ et al. | Effects of extruded soybeans and forage source on fermentation by rumen microorganisms in continuous culture. | 1994 | J. Dairy Sci. | pmid:8083419 |
Schreck R et al. | Retinoids stimulate type I iodothyronine 5'-deiodinase activity in human follicular thyroid carcinoma cell lines. | 1994 | J. Clin. Endocrinol. Metab. | pmid:8077363 |
Austin C and Wray S | A quantitative study of the relation between intracellular pH and force in rat mesenteric vascular smooth muscle. | 1994 | Pflugers Arch. | pmid:8072846 |
Chen H et al. | Characterization of two promoters of a rat pregnancy-specific glycoprotein gene. | 1994 | Biochemistry | pmid:8068638 |
Wadee AA et al. | HLA expression in hepatocellular carcinoma cell lines. | 1994 | Clin. Exp. Immunol. | pmid:8050184 |
Kaptein A et al. | Butyrate stimulates the secretion of apolipoprotein B-100-containing lipoproteins from HepG2 cells by inhibiting the intracellular degradation. | 1994 | Biochim. Biophys. Acta | pmid:8049249 |
Peterec SM et al. | Butyrate modulates surfactant protein mRNA in fetal rat lung by altering mRNA transcription and stability. | 1994 | Am. J. Physiol. | pmid:8048547 |
Frankel W et al. | Butyrate increases colonocyte protein synthesis in ulcerative colitis. | 1994 | J. Surg. Res. | pmid:8041140 |
Shadan FF et al. | n-Butyrate, a cell cycle blocker, inhibits the replication of polyomaviruses and papillomaviruses but not that of adenoviruses and herpesviruses. | 1994 | J. Virol. | pmid:8035479 |
Yamaguchi Y et al. | Functional characterization of the promoter for the gene encoding human eosinophil peroxidase. | 1994 | J. Biol. Chem. | pmid:8034708 |
Waagen V et al. | Homochiral glycerol derivatives by lipase-catalysed racemate resolution. | 1994 | Protein Eng. | pmid:8029217 |
Sandvig K et al. | Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP. | 1994 | J. Cell Biol. | pmid:8027186 |