butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Acidosis D000138 13 associated lipids
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Alzheimer Disease D000544 76 associated lipids
Anaplasia D000708 1 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Angina Pectoris D000787 27 associated lipids
Aphakia, Postcataract D001036 1 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Astigmatism D001251 1 associated lipids
Ataxia Telangiectasia D001260 6 associated lipids
Sarcoma, Avian D001357 2 associated lipids
Body Weight D001835 333 associated lipids
Brain Diseases D001927 27 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Burns D002056 34 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Cattle Diseases D002418 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Colitis D003092 69 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Colorectal Neoplasms, Hereditary Nonpolyposis D003123 2 associated lipids
Constipation D003248 8 associated lipids
Corneal Diseases D003316 13 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Dental Leakage D003763 5 associated lipids
Dentin, Secondary D003809 2 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Diarrhea D003967 32 associated lipids
Disease Models, Animal D004195 4 associated lipids
Diverticulitis D004238 1 associated lipids
Diverticulitis, Colonic D004239 1 associated lipids
Dysentery D004403 4 associated lipids
Edema D004487 152 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Facial Injuries D005151 1 associated lipids
Fatty Liver D005234 48 associated lipids
Fragile X Syndrome D005600 5 associated lipids
Glioma D005910 112 associated lipids
Glycogen Storage Disease Type II D006009 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Hemolysis D006461 131 associated lipids
Hemorrhoids D006484 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Alva-Murillo N et al. The activation of the TLR2/p38 pathway by sodium butyrate in bovine mammary epithelial cells is involved in the reduction of Staphylococcus aureus internalization. 2015 Mol. Immunol. pmid:26471700
Chen Y et al. Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice. 2015 Cardiovasc Diabetol pmid:26245924
Wang X et al. Sodium butyrate alleviates adipocyte inflammation by inhibiting NLRP3 pathway. 2015 Sci Rep pmid:26234821
Regestein L et al. Impact of butyric acid on butanol formation by Clostridium pasteurianum. 2015 Bioresour. Technol. pmid:26233327
Baroi GN et al. Butyric acid fermentation from pretreated and hydrolysed wheat straw by an adapted Clostridium tyrobutyricum strain. 2015 Microb Biotechnol pmid:26230610
Ulfina GG et al. Modulation of post-partum reproductive performance in dairy cows through supplementation of long- or short-chain fatty acids during transition period. 2015 J Anim Physiol Anim Nutr (Berl) pmid:25879374
Blank M et al. Enhancement of memory consolidation by the histone deacetylase inhibitor sodium butyrate in aged rats. 2015 Neurosci. Lett. pmid:25837444
Gonnella R et al. PKC theta and p38 MAPK activate the EBV lytic cycle through autophagy induction. 2015 Biochim. Biophys. Acta pmid:25827954
Rodrigues MF et al. Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin A on the energy metabolism of breast cancer cells. 2015 J. Cell. Biochem. pmid:25510910
Ledaki I et al. Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition. 2015 Oncotarget pmid:26305601
Tiwari P et al. Combinatorial chemopreventive effect of butyric acid, nicotinamide and calcium glucarate against the 7,12-dimethylbenz(a)anthracene induced mouse skin tumorigenesis attained by enhancing the induction of intrinsic apoptotic events. 2015 Chem. Biol. Interact. pmid:25478867
Ray A et al. Absorption spectrophotometric, fluorescence and quantum chemical investigations on non-covalent interaction between PC₇₀BM and designed diporphyrin in solution. 2015 Spectrochim Acta A Mol Biomol Spectrosc pmid:25138385
Szymanowska-Powałowska D and Kubiak P Effect of 1,3-propanediol, organic acids, and ethanol on growth and metabolism of Clostridium butyricum DSP1. 2015 Appl. Microbiol. Biotechnol. pmid:25524700
Xiong XR et al. Sodium butyrate improves the cloned yak embryo viability and corrects gene expression patterns. 2015 Zygote pmid:23759515
Walia K et al. Effect of feeding sodium butyrate in the late finishing period on Salmonella carriage, seroprevalence, and growth of finishing pigs. 2016 Prev. Vet. Med. pmid:27544256
Otto A et al. The protein inventory of Clostridium difficile grown in complex and minimal medium. 2016 Proteomics Clin Appl pmid:27511832
Yin F et al. Transcriptome Analysis Reveals Regulation of Gene Expression for Lipid Catabolism in Young Broilers by Butyrate Glycerides. 2016 PLoS ONE pmid:27508934
Moore JB et al. The Epigenetic Regulator HDAC1 Modulates Transcription of a Core Cardiogenic Program in Human Cardiac Mesenchymal Stromal Cells Through a p53-Dependent Mechanism. 2016 Stem Cells pmid:27501845
Lakhter AJ et al. Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth. 2016 J. Biol. Chem. pmid:27539851
Fialova B et al. Epigenetic modulation of AR gene expression in prostate cancer DU145 cells with the combination of sodium butyrate and 5'-Aza-2'-deoxycytidine. 2016 Oncol. Rep. pmid:27499010
Hou G et al. Tetracycline removal and effect on the formation and degradation of extracellular polymeric substances and volatile fatty acids in the process of hydrogen fermentation. 2016 Bioresour. Technol. pmid:27070285
Longpré J et al. Impact of mash feeding versus pellets on propionic/butyric acid levels and on total load in the gastrointestinal tract of growing pigs. 2016 J. Anim. Sci. pmid:27065267
Wang A et al. Sodium butyrate mitigates in vitro ammonia generation in cecal content of laying hens. 2016 Environ Sci Pollut Res Int pmid:27154844
Kapuvári B et al. Improved in vivo antitumor effect of a daunorubicin - GnRH-III bioconjugate modified by apoptosis inducing agent butyric acid on colorectal carcinoma bearing mice. 2016 Invest New Drugs pmid:27146514
Wu Y et al. Influence of Butyrate Loaded Clinoptilolite Dietary Supplementation on Growth Performance, Development of Intestine and Antioxidant Capacity in Broiler Chickens. 2016 PLoS ONE pmid:27104860
Rivera-Chávez F et al. Depletion of Butyrate-Producing Clostridia from the Gut Microbiota Drives an Aerobic Luminal Expansion of Salmonella. 2016 Cell Host Microbe pmid:27078066
Lazarova DL and Bordonaro M Vimentin, colon cancer progression and resistance to butyrate and other HDACis. 2016 J. Cell. Mol. Med. pmid:27072512
Cang S et al. Hypoacetylation, hypomethylation, and dephosphorylation of H2B histones and excessive histone deacetylase activity in DU-145 prostate cancer cells. 2016 J Hematol Oncol pmid:26759222
Kaczmarek SA et al. Effect of different doses of coated butyric acid on growth performance and energy utilization in broilers. 2016 Poult. Sci. pmid:26740137
Jung JM et al. Pseudo catalytic transformation of volatile fatty acids into fatty acid methyl esters. 2016 Bioresour. Technol. pmid:26720136
Xin F et al. Strategies for production of butanol and butyl-butyrate through lipase-catalyzed esterification. 2016 Bioresour. Technol. pmid:26710347
Cibis KG et al. Isolation of acetic, propionic and butyric acid-forming bacteria from biogas plants. 2016 J. Biotechnol. pmid:26779817
Russo R et al. Sodium butyrate and its synthetic amide derivative modulate nociceptive behaviors in mice. 2016 Pharmacol. Res. pmid:26675718
Polycarpo GV et al. Effects of lipid sources, lysophospholipids and organic acids in maize-based broiler diets on nutrient balance, liver concentration of fat-soluble vitamins, jejunal microbiota and performance. 2016 Br. Poult. Sci. pmid:27494540
Zhang Y et al. Monitoring Intracellular pH Change with a Genetically Encoded and Ratiometric Luminescence Sensor in Yeast and Mammalian Cells. 2016 Methods Mol. Biol. pmid:27424899
Villain H et al. HDAC inhibition promotes both initial consolidation and reconsolidation of spatial memory in mice. 2016 Sci Rep pmid:27270584
Zhang Q et al. Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced colitis by a butyrate-producing bacterium. 2016 Sci Rep pmid:27264309
Xiong H et al. Butyrate upregulates endogenous host defense peptides to enhance disease resistance in piglets via histone deacetylase inhibition. 2016 Sci Rep pmid:27230284
Anderson NA et al. Synthesis and determination of absolute configuration of a non-peptidic αvβ6 integrin antagonist for the treatment of idiopathic pulmonary fibrosis. 2016 Org. Biomol. Chem. pmid:27226381
Subramanian U et al. Retinoic acid and sodium butyrate suppress the cardiac expression of hypertrophic markers and proinflammatory mediators in Npr1 gene-disrupted haplotype mice. 2016 Physiol. Genomics pmid:27199456
Bastiaansen JA et al. Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate. 2016 Sci Rep pmid:27150735
Seki K et al. Varying butyric acid amounts induce different stress- and cell death-related signals in nerve growth factor-treated PC12 cells: implications in neuropathic pain absence during periodontal disease progression. 2016 Apoptosis pmid:26994613
Vazquez-DeRose J et al. Hypocretin/orexin antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain. 2016 Brain Struct Funct pmid:25431268
Popp D et al. The alkaloid gramine in the anaerobic digestion process-inhibition and adaptation of the methanogenic community. 2016 Appl. Microbiol. Biotechnol. pmid:27138201
Endesfelder D et al. Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production. 2016 Microbiome pmid:27114075
Park MJ and Sohrabji F The histone deacetylase inhibitor, sodium butyrate, exhibits neuroprotective effects for ischemic stroke in middle-aged female rats. 2016 J Neuroinflammation pmid:27905989
Gallo A et al. Relationships among ensiling, nutritional, fermentative, microbiological traits and contamination in corn silages addressed with partial least squares regression. 2016 J. Anim. Sci. pmid:27898868
Estensoro I et al. Dietary Butyrate Helps to Restore the Intestinal Status of a Marine Teleost (Sparus aurata) Fed Extreme Diets Low in Fish Meal and Fish Oil. 2016 PLoS ONE pmid:27898676
Chang MC et al. Effect of Butyrate on Collagen Expression, Cell Viability, Cell Cycle Progression and Related Proteins Expression of MG-63 Osteoblastic Cells. 2016 PLoS ONE pmid:27893752
Zhang T et al. Sodium Butyrate Reduces Colitogenic Immunoglobulin A-Coated Bacteria and Modifies the Composition of Microbiota in IL-10 Deficient Mice. 2016 Nutrients pmid:27886121