butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Medina V et al. | Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway. | 1997 | Cancer Res. | pmid:9288776 |
Talley NA et al. | Short-chain fatty acids in the treatment of radiation proctitis: a randomized, double-blind, placebo-controlled, cross-over pilot trial. | 1997 | Dis. Colon Rectum | pmid:9293933 |
Ohno Y et al. | Macrophage inflammatory protein-2: chromosomal regulation in rat small intestinal epithelial cells. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9294201 |
Lewis SJ and Heaton KW | Increasing butyrate concentration in the distal colon by accelerating intestinal transit. | 1997 | Gut | pmid:9301506 |
Chénais B et al. | Time-course of butyric acid-induced differentiation in human K562 leukemic cell line: rapid increase in gamma-globin, porphobilinogen deaminase and NF-E2 mRNA levels. | 1997 | Leukemia | pmid:9305615 |
Cuisset L et al. | The effects of sodium butyrate on transcription are mediated through activation of a protein phosphatase. | 1997 | J. Biol. Chem. | pmid:9305863 |
Birkett AM et al. | Dietary intake and faecal excretion of carbohydrate by Australians: importance of achieving stool weights greater than 150 g to improve faecal markers relevant to colon cancer risk. | 1997 | Eur J Clin Nutr | pmid:9306090 |
Ishiguro K and Sartorelli AC | Clonal variability in beta-globin mRNA content in an interleukin-3-dependent bone marrow cell line transfected with the erythropoietin receptor before and after stimulation with erythropoietin. | 1997 | Blood | pmid:9310478 |
Hague A et al. | bcl-2 and bak may play a pivotal role in sodium butyrate-induced apoptosis in colonic epithelial cells; however overexpression of bcl-2 does not protect against bak-mediated apoptosis. | 1997 | Int. J. Cancer | pmid:9311611 |
Dohi H et al. | Intake stimulants in perennial ryegrass (Lolium perenne L.) fed to sheep. | 1997 | J. Dairy Sci. | pmid:9313150 |
Engelhard HH et al. | Molecular characterization of glioblastoma cell differentiation. | 1997 | Neurosurgery | pmid:9316051 |
Scannell JP et al. | Antimetabolites produced by microorganisms. XIII. The synthesis and microbiological production of a novel amino acid, L-2-amino-4-(2-aminoethoxy) butanoic acid. | 1976 | J. Antibiot. | pmid:931793 |
Kaiser E and Weiss K | [Fermentation process during the ensiling of green forage low in nitrate. 2. Fermentation process after supplementation of nitrate, nitrite, lactic acid bacteria and formic acid]. | 1997 | Arch Tierernahr | pmid:9324922 |
Janson W et al. | Butyrate modulates DNA-damage-induced p53 response by induction of p53-independent differentiation and apoptosis. | 1997 | Oncogene | pmid:9333015 |
Sovová V et al. | Differences of alkaline phosphatase and arginase activities in human colorectal carcinoma cell lines. | 1997 | Folia Biol. (Praha) | pmid:9338115 |
Garcia-Bermejo L et al. | Modulation of heat-shock protein 70 (HSP70) gene expression by sodium butyrate in U-937 promonocytic cells: relationships with differentiation and apoptosis. | 1997 | Exp. Cell Res. | pmid:9344607 |
Vecchia MG et al. | Acetate and propionate potentiate the antiproliferative effect of butyrate on RBL-2H3 growth. | 1997 | Gen. Pharmacol. | pmid:9347317 |
Loukopoulos D | New therapies for the haemoglobinopathies. | 1997 | J Intern Med Suppl | pmid:9350181 |
Kavaliers M et al. | Opioid and non-opioid NMDA-mediated predator-induced analgesia in mice and the effects of parasitic infection. | 1997 | Brain Res. | pmid:9359582 |
O'Mara FP et al. | Rumen fermentation and nutrient flows for cows fed grass and grass supplemented with molassed beet pulp pellets. | 1997 | J. Dairy Sci. | pmid:9361218 |