butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Acidosis D000138 13 associated lipids
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Alzheimer Disease D000544 76 associated lipids
Anaplasia D000708 1 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Angina Pectoris D000787 27 associated lipids
Aphakia, Postcataract D001036 1 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Astigmatism D001251 1 associated lipids
Ataxia Telangiectasia D001260 6 associated lipids
Sarcoma, Avian D001357 2 associated lipids
Body Weight D001835 333 associated lipids
Brain Diseases D001927 27 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Burns D002056 34 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Cattle Diseases D002418 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Colitis D003092 69 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Colorectal Neoplasms, Hereditary Nonpolyposis D003123 2 associated lipids
Constipation D003248 8 associated lipids
Corneal Diseases D003316 13 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Dental Leakage D003763 5 associated lipids
Dentin, Secondary D003809 2 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Diarrhea D003967 32 associated lipids
Disease Models, Animal D004195 4 associated lipids
Diverticulitis D004238 1 associated lipids
Diverticulitis, Colonic D004239 1 associated lipids
Dysentery D004403 4 associated lipids
Edema D004487 152 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Facial Injuries D005151 1 associated lipids
Fatty Liver D005234 48 associated lipids
Fragile X Syndrome D005600 5 associated lipids
Glioma D005910 112 associated lipids
Glycogen Storage Disease Type II D006009 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Hemolysis D006461 131 associated lipids
Hemorrhoids D006484 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

Download all related citations
Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Barnard JA et al. Short chain fatty acid regulation of intestinal gene expression. 1997 Adv. Exp. Med. Biol. pmid:9361821
Velázquez OC et al. Butyrate and the colonocyte. Production, absorption, metabolism, and therapeutic implications. 1997 Adv. Exp. Med. Biol. pmid:9361838
Velázquez OC and Rombeau JL Butyrate. Potential role in colon cancer prevention and treatment. 1997 Adv. Exp. Med. Biol. pmid:9361842
Singh M Calcium and cyclic nucleotide interaction in secretion of amylase from rat pancreas in vitro. 1979 J. Physiol. (Lond.) pmid:93637
Payne KL et al. Modulation of T3-induced sex hormone-binding globulin secretion by human hepatoblastoma cells. 1997 Eur. J. Endocrinol. pmid:9368511
Velázquez OC et al. Butyrate inhibits deoxycholate-induced increase in colonic mucosal DNA and protein synthesis in vivo. 1997 Dis. Colon Rectum pmid:9369115
Kolesnitchenko V et al. A major human immunodeficiency virus type 1-initiated killing pathway distinct from apoptosis. 1997 J. Virol. pmid:9371641
Faller DV and Perrine SP Butyrate in the treatment of sickle cell disease and beta-thalassemia. 1995 Curr. Opin. Hematol. pmid:9371980
Coradini D et al. Effect of sodium butyrate on human breast cancer cell lines. 1997 Mar-Apr Cell Prolif. pmid:9375027
Onaga T et al. Effect of pituitary adenylate cyclase-activating polypeptide on exocrine and endocrine secretion in the ovine pancreas. 1996 Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. pmid:9375356
Hassig CA et al. Fiber-derived butyrate and the prevention of colon cancer. 1997 Chem. Biol. pmid:9384528
Vimard C et al. Changes in the sedimentation properties of acetycholinesterase during neuroblastoma differentiation. 1976 Biochimie pmid:938691
Palmer DG et al. Modulation of p53 expression in cultured colonic adenoma cell lines by the naturally occurring lumenal factors butyrate and deoxycholate. 1997 Int. J. Cancer pmid:9398049
Cordel S et al. 5-Fluorouracil-resistant colonic tumors are highly responsive to sodium butyrate/interleukin-2 bitherapy in rats. 1997 Int. J. Cancer pmid:9399677
Moore JW et al. Thiolmethyltransferase activity in the human colonic mucosa: implications for ulcerative colitis. 1997 J. Gastroenterol. Hepatol. pmid:9407333
Böhmig GA et al. n-butyrate downregulates the stimulatory function of peripheral blood-derived antigen-presenting cells: a potential mechanism for modulating T-cell responses by short-chain fatty acids. 1997 Immunology pmid:9415032
Callus BA et al. Haemoglobin synthesis in erythropoietin-stimulated J2E cells does not require increased numbers of transferrin receptors. 1997 Eur. J. Biochem. pmid:9428699
Yabushita H et al. Emergence of an irreversible differentiated subclone from the poorly differentiated ovarian adenocarcinoma cell line AMOC-2 treated with sodium butyrate. 1997 J. Obstet. Gynaecol. Res. pmid:9433040
Ono M et al. Resin glycosides. XXV. Multifidins I and II, new jalapins, from the seed of Quamoclit x multifida. 1997 Chem. Pharm. Bull. pmid:9433765
Medina V et al. Sodium butyrate inhibits carcinoma development in a 1,2-dimethylhydrazine-induced rat colon cancer. 1998 Jan-Feb JPEN J Parenter Enteral Nutr pmid:9437648