butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Gabris C et al. | Analysis of the key enzymes of butyric and acetic acid fermentation in biogas reactors. | 2015 | Microb Biotechnol | pmid:26086956 |
Fei Q et al. | Lipid production by microalgae Chlorella protothecoides with volatile fatty acids (VFAs) as carbon sources in heterotrophic cultivation and its economic assessment. | 2015 | Bioprocess Biosyst Eng | pmid:25332127 |
Fotschki B et al. | Ellagitannins and Flavan-3-ols from Raspberry Pomace Modulate Caecal Fermentation Processes and Plasma Lipid Parameters in Rats. | 2015 | Molecules | pmid:26703543 |
Tian H et al. | Anaerobic co-digestion of kitchen waste and pig manure with different mixing ratios. | 2015 | J. Biosci. Bioeng. | pmid:25617184 |
Zheng XT et al. | Sodium butyrate down-regulates tristetraprolin-mediated cyclin B1 expression independent of the formation of processing bodies. | 2015 | Int. J. Biochem. Cell Biol. | pmid:26555753 |
Moran JK et al. | The Scent of Blood: A Driver of Human Behavior? | 2015 | PLoS ONE | pmid:26397374 |
Imai K et al. | Involvement of Sp1 in butyric acid-induced HIV-1 gene expression. | 2015 | Cell. Physiol. Biochem. | pmid:26383101 |
Pandey K et al. | Histone deacetylase inhibition facilitates massed pattern-induced synaptic plasticity and memory. | 2015 | Learn. Mem. | pmid:26373830 |
Rajendran VM et al. | Na-H Exchanger Isoform-2 (NHE2) Mediates Butyrate-dependent Na+ Absorption in Dextran Sulfate Sodium (DSS)-induced Colitis. | 2015 | J. Biol. Chem. | pmid:26350456 |
Rawłuszko-Wieczorek AA et al. | Effect of DNA methylation profile on OATP3A1 and OATP4A1 transcript levels in colorectal cancer. | 2015 | Biomed. Pharmacother. | pmid:26349991 |
Sobolewski C et al. | Histone Deacetylase Inhibitors Activate Tristetraprolin Expression through Induction of Early Growth Response Protein 1 (EGR1) in Colorectal Cancer Cells. | 2015 | Biomolecules | pmid:26343742 |
Fomina-Yadlin D et al. | Transcriptome analysis of a CHO cell line expressing a recombinant therapeutic protein treated with inducers of protein expression. | 2015 | J. Biotechnol. | pmid:26325199 |
Sun J et al. | Neuroprotective Effect of Sodium Butyrate against Cerebral Ischemia/Reperfusion Injury in Mice. | 2015 | Biomed Res Int | pmid:26064905 |
Sharma S et al. | Beneficial effects of sodium butyrate in 6-OHDA induced neurotoxicity and behavioral abnormalities: Modulation of histone deacetylase activity. | 2015 | Behav. Brain Res. | pmid:26048426 |
Li H et al. | Administration of progranulin (PGRN) triggers ER stress and impairs insulin sensitivity via PERK-eIF2α-dependent manner. | 2015 | Cell Cycle | pmid:26039714 |
Sobahan MA et al. | Allyl isothiocyanate induces stomatal closure in Vicia faba. | 2015 | Biosci. Biotechnol. Biochem. | pmid:26027691 |
Lee KM et al. | Butyric acid production from red algae by a newly isolated Clostridium sp. S1. | 2015 | Biotechnol. Lett. | pmid:26026964 |
Jiang L et al. | Thermophilic hydrogen-producing bacteria inhabiting deep-sea hydrothermal environments represented by Caloranaerobacter. | 2015 | Res. Microbiol. | pmid:26026841 |
Agarwal U et al. | Role of rumen butyrate in regulation of nitrogen utilization and urea nitrogen kinetics in growing sheep. | 2015 | J. Anim. Sci. | pmid:26020334 |
Gao F et al. | The Effect of Processing Additives on Energetic Disorder in Highly Efficient Organic Photovoltaics: A Case Study on PBDTTT-C-T:PC71 BM. | 2015 | Adv. Mater. Weinheim | pmid:26016473 |
Levy AW et al. | Effect of feeding an encapsulated source of butyric acid (ButiPEARL) on the performance of male Cobb broilers reared to 42 d of age. | 2015 | Poult. Sci. | pmid:26015588 |
Liu H et al. | Post-occlusion administration of sodium butyrate attenuates cognitive impairment in a rat model of chronic cerebral hypoperfusion. | 2015 | Pharmacol. Biochem. Behav. | pmid:26013850 |
Cho JH et al. | MicroRNA-31 is a transcriptional target of histone deacetylase inhibitors and a regulator of cellular senescence. | 2015 | J. Biol. Chem. | pmid:25737447 |
Walsh ME et al. | Butyrate prevents muscle atrophy after sciatic nerve crush. | 2015 | Muscle Nerve | pmid:25727783 |
Kowalski ZM et al. | Effect of microencapsulated sodium butyrate in the close-up diet on performance of dairy cows in the early lactation period. | 2015 | J. Dairy Sci. | pmid:25726104 |
Pierra M et al. | Specific and efficient electrochemical selection of Geoalkalibacter subterraneus and Desulfuromonas acetoxidans in high current-producing biofilms. | 2015 | Bioelectrochemistry | pmid:25717030 |
Bianchi N et al. | Erythroid differentiation ability of butyric acid analogues: identification of basal chemical structures of new inducers of foetal haemoglobin. | 2015 | Eur. J. Pharmacol. | pmid:25701725 |
Tan W et al. | Sodium butyrate-induced histone hyperacetylation up-regulating WT1 expression in porcine kidney fibroblasts. | 2015 | Biotechnol. Lett. | pmid:25700826 |
Zhang T et al. | Sodium Butyrate Reduces Organ Injuries in Mice with Severe Acute Pancreatitis Through Inhibiting HMGB1 Expression. | 2015 | Dig. Dis. Sci. | pmid:25686746 |
Wanat P et al. | Short communication: Effect of inclusion rate of microencapsulated sodium butyrate in starter mixture for dairy calves. | 2015 | J. Dairy Sci. | pmid:25648817 |
Gerace E et al. | Interplay between histone acetylation/deacetylation and poly(ADP-ribosyl)ation in the development of ischemic tolerance in vitro. | 2015 | Neuropharmacology | pmid:25623965 |
Agostini S et al. | Barley beta-glucan promotes MnSOD expression and enhances angiogenesis under oxidative microenvironment. | 2015 | J. Cell. Mol. Med. | pmid:25388628 |
Barichello T et al. | Sodium Butyrate Prevents Memory Impairment by Re-establishing BDNF and GDNF Expression in Experimental Pneumococcal Meningitis. | 2015 | Mol. Neurobiol. | pmid:25284351 |
Yoo DY et al. | Sodium butyrate, a histone deacetylase Inhibitor, ameliorates SIRT2-induced memory impairment, reduction of cell proliferation, and neuroblast differentiation in the dentate gyrus. | 2015 | Neurol. Res. | pmid:24963697 |
Dengler F et al. | Both butyrate incubation and hypoxia upregulate genes involved in the ruminal transport of SCFA and their metabolites. | 2015 | J Anim Physiol Anim Nutr (Berl) | pmid:24804847 |
Park SO and Park BS | Bifidogenic effect of grain larvae extract on serum lipid, glucose and intestinal microflora in rats. | 2015 | J. Biosci. | pmid:26333397 |
Stertz L et al. | Histone deacetylase activity and brain-derived neurotrophic factor (BDNF) levels in a pharmacological model of mania. | 2014 Jan-Mar | Rev Bras Psiquiatr | pmid:24346357 |
Machiels K et al. | A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis. | 2014 | Gut | pmid:24021287 |
Wang C et al. | A survey of fermentation products and bacterial communities in corn silage produced in a bunker silo in China. | 2014 | Anim. Sci. J. | pmid:23638801 |
Vidrine K et al. | Resistant starch from high amylose maize (HAM-RS2) and dietary butyrate reduce abdominal fat by a different apparent mechanism. | 2014 | Obesity (Silver Spring) | pmid:23630079 |
Liu J et al. | Sodium butyrate promotes the differentiation of rat bone marrow mesenchymal stem cells to smooth muscle cells through histone acetylation. | 2014 | PLoS ONE | pmid:25548915 |
Vicente F et al. | Subclinical ketosis on dairy cows in transition period in farms with contrasting butyric acid contents in silages. | 2014 | ScientificWorldJournal | pmid:25525616 |
Szymanowska-Powałowska D et al. | Biotechnological potential of Clostridium butyricum bacteria. | 2014 | Braz. J. Microbiol. | pmid:25477923 |
Brocato J et al. | Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression. | 2014 | J. Biol. Chem. | pmid:25266719 |
Kondo Y et al. | Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells. | 2014 | PLoS ONE | pmid:25084468 |
Vargas JE et al. | Inhibition of HDAC increases the senescence induced by natural polyphenols in glioma cells. | 2014 | Biochem. Cell Biol. | pmid:25070040 |
Ozadali K et al. | Synthesis and antimycobacterial activities of some new thiazolylhydrazone derivatives. | 2014 | Bioorg. Med. Chem. Lett. | pmid:24631185 |
Shen H et al. | BMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progression. | 2014 | J. Cell. Mol. Med. | pmid:24571310 |
Karki P et al. | Yin Yang 1 is a repressor of glutamate transporter EAAT2, and it mediates manganese-induced decrease of EAAT2 expression in astrocytes. | 2014 | Mol. Cell. Biol. | pmid:24469401 |
Pérez-Carro R et al. | Functional analysis and in vitro correction of splicing FAH mutations causing tyrosinemia type I. | 2014 | Clin. Genet. | pmid:23895425 |
Miltko R et al. | Can fungal zoospores be the source of energy for the rumen protozoa Eudiplodinium maggii? | 2014 | Anaerobe | pmid:24012688 |
Takuma K et al. | Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism. | 2014 | Pharmacol. Biochem. Behav. | pmid:25240644 |
Valvassori SS et al. | Sodium butyrate functions as an antidepressant and improves cognition with enhanced neurotrophic expression in models of maternal deprivation and chronic mild stress. | 2014 | Curr Neurovasc Res | pmid:25233278 |
Nankova BB et al. | Enteric bacterial metabolites propionic and butyric acid modulate gene expression, including CREB-dependent catecholaminergic neurotransmission, in PC12 cells--possible relevance to autism spectrum disorders. | 2014 | PLoS ONE | pmid:25170769 |
Bilgraer R et al. | A new approach combining LC-MS and multivariate statistical analysis for revealing changes in histone modification levels. | 2014 | Mol Biosyst | pmid:25167371 |
Xu G et al. | SAHA regulates histone acetylation, Butyrylation, and protein expression in neuroblastoma. | 2014 | J. Proteome Res. | pmid:25160476 |
Khan S and Jena G | Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-β1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats. | 2014 | Food Chem. Toxicol. | pmid:25158305 |
Moeinian M et al. | Beneficial effect of butyrate, Lactobacillus casei and L-carnitine combination in preference to each in experimental colitis. | 2014 | World J. Gastroenterol. | pmid:25152589 |
Chou AH et al. | Polyglutamine-expanded ataxin-3 impairs long-term depression in Purkinje neurons of SCA3 transgenic mouse by inhibiting HAT and impairing histone acetylation. | 2014 | Brain Res. | pmid:25139423 |
Reindl A et al. | Enumeration of clostridia in goat milk using an optimized membrane filtration technique. | 2014 | J. Dairy Sci. | pmid:25129496 |
Kanski R et al. | Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network. | 2014 | J. Cell. Sci. | pmid:25128567 |
Lee JM et al. | Direct hydrogenation of biomass-derived butyric acid to n-butanol over a ruthenium-tin bimetallic catalyst. | 2014 | ChemSusChem | pmid:25123894 |
Lopez CA et al. | Collateral damage: microbiota-derived metabolites and immune function in the antibiotic era. | 2014 | Cell Host Microbe | pmid:25121745 |
Peterson EC and Daugulis AJ | Demonstration of in situ product recovery of butyric acid via CO2 -facilitated pH swings and medium development in two-phase partitioning bioreactors. | 2014 | Biotechnol. Bioeng. | pmid:23996152 |
Tiwari P and Gupta KP | Modulation of miR-203 and its regulators as a function of time during the development of 7, 12 dimethylbenz [a] anthracene induced mouse skin tumors in presence or absence of the antitumor agents. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24792773 |
Pasvolsky R et al. | Butyric acid released during milk lipolysis triggers biofilm formation of Bacillus species. | 2014 | Int. J. Food Microbiol. | pmid:24801271 |
Maggio A et al. | Daily sodium butyrate enema for the prevention of radiation proctitis in prostate cancer patients undergoing radical radiation therapy: results of a multicenter randomized placebo-controlled dose-finding phase 2 study. | 2014 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:24803033 |
Ellis JT et al. | Microbial bioproducts from cheese whey through fermentation with wastewater sludge Clostridium isolates. | 2014 | Can. J. Microbiol. | pmid:24898684 |
Ochiai K and Kurita-Ochiai T | [Alternative effects of a metabolic by-product, butyric acid, produced by oral anaerobes]. | 2014 | Nippon Yakurigaku Zasshi | pmid:25109521 |
Wang J et al. | Comparative effects of sodium butyrate and flavors on feed intake of lactating sows and growth performance of piglets. | 2014 | Anim. Sci. J. | pmid:24773759 |
Liu W et al. | Effects of dietary microencapsulated sodium butyrate on growth, intestinal mucosal morphology, immune response and adhesive bacteria in juvenile common carp (Cyprinus carpio) pre-fed with or without oxidised oil. | 2014 | Br. J. Nutr. | pmid:24774835 |
Saini M et al. | Metabolic engineering of Escherichia coli for production of butyric acid. | 2014 | J. Agric. Food Chem. | pmid:24773075 |
Dareioti MA et al. | Effect of pH on the anaerobic acidogenesis of agroindustrial wastewaters for maximization of bio-hydrogen production: a lab-scale evaluation using batch tests. | 2014 | Bioresour. Technol. | pmid:24759638 |
Castellano JF et al. | Reassessing the effects of histone deacetylase inhibitors on hippocampal memory and cognitive aging. | 2014 | Hippocampus | pmid:24753063 |
Zhou X et al. | Comparison of the effects of high energy carbon heavy ion irradiation and Eucommia ulmoides Oliv. on biosynthesis butyric acid efficiency in Clostridium tyrobutyricum. | 2014 | Bioresour. Technol. | pmid:24704888 |
Jang YS et al. | Metabolic engineering of Clostridium acetobutylicum for butyric acid production with high butyric acid selectivity. | 2014 | Metab. Eng. | pmid:24704310 |
Syngiridis K et al. | Favouring butyrate production for a new generation biofuel by acidogenic glucose fermentation using cells immobilised on γ-alumina. | 2014 | Bioresour. Technol. | pmid:24690582 |
Sarkar A et al. | Hippocampal HDAC4 contributes to postnatal fluoxetine-evoked depression-like behavior. | 2014 | Neuropsychopharmacology | pmid:24663010 |
Csikó G et al. | Effects of dietary sodium butyrate on hepatic biotransformation and pharmacokinetics of erythromycin in chickens. | 2014 | J. Vet. Pharmacol. Ther. | pmid:24628435 |
Han A et al. | Possible additional antidepressant-like mechanism of sodium butyrate: targeting the hippocampus. | 2014 | Neuropharmacology | pmid:24607816 |
Park HG et al. | Repeated treatment with electroconvulsive seizures induces HDAC2 expression and down-regulation of NMDA receptor-related genes through histone deacetylation in the rat frontal cortex. | 2014 | Int. J. Neuropsychopharmacol. | pmid:24606669 |
Aguilar EC et al. | Butyrate impairs atherogenesis by reducing plaque inflammation and vulnerability and decreasing NFκB activation. | 2014 | Nutr Metab Cardiovasc Dis | pmid:24602606 |
Sabra W et al. | Improved n-butanol production by a non-acetone producing Clostridium pasteurianum DSMZ 525 in mixed substrate fermentation. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24584460 |
Blank M et al. | Basolateral amygdala activity is required for enhancement of memory consolidation produced by histone deacetylase inhibition in the hippocampus. | 2014 | Neurobiol Learn Mem | pmid:24583371 |
Possebom G et al. | Esterification of fatty acids by Penicillium crustosum lipase in a membrane reactor. | 2014 | J. Sci. Food Agric. | pmid:24578290 |
Xiao M et al. | Sodium butyrate induces apoptosis of human colon cancer cells by modulating ERK and sphingosine kinase 2. | 2014 | Biomed. Environ. Sci. | pmid:24709100 |
Hu WT et al. | Transient folate deprivation in combination with small-molecule compounds facilitates the generation of somatic cell-derived pluripotent stem cells in mice. | 2014 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:24710923 |
Yamamura T et al. | Sodium butyrate, a histone deacetylase inhibitor, regulates Lymphangiogenic factors in oral cancer cell line HSC-3. | 2014 | Anticancer Res. | pmid:24692699 |
Kumar P et al. | All-trans retinoic acid and sodium butyrate enhance natriuretic peptide receptor a gene transcription: role of histone modification. | 2014 | Mol. Pharmacol. | pmid:24714214 |
Dos Santos MP et al. | In vitro antitumor effect of sodium butyrate and zoledronic acid combined with traditional chemotherapeutic drugs: a paradigm of synergistic molecular targeting in the treatment of Ewing sarcoma. | 2014 | Oncol. Rep. | pmid:24316794 |
Lee SM et al. | Digital mRNA profiling of N-glycosylation gene expression in recombinant Chinese hamster ovary cells treated with sodium butyrate. | 2014 | J. Biotechnol. | pmid:24333461 |
Dostal A et al. | Iron supplementation promotes gut microbiota metabolic activity but not colitis markers in human gut microbiota-associated rats. | 2014 | Br. J. Nutr. | pmid:24555487 |
Tailor D et al. | Sodium butyrate induces DRP1-mediated mitochondrial fusion and apoptosis in human colorectal cancer cells. | 2014 | Mitochondrion | pmid:24177748 |
Khan S and Jena GB | Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: study in juvenile diabetic rat. | 2014 | Chem. Biol. Interact. | pmid:24530320 |
Peterson AB et al. | Dose-dependent effects of wheel running on cocaine-seeking and prefrontal cortex Bdnf exon IV expression in rats. | 2014 | Psychopharmacology (Berl.) | pmid:24173624 |
Ferreira AC et al. | Histone deacetylase inhibitor prevents cell growth in Burkitt's lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101. | 2014 | Ann. Hematol. | pmid:24577510 |
Fang CL et al. | Effects of sodium butyrate on growth performance, haematological and immunological characteristics of weanling piglets. | 2014 | J Anim Physiol Anim Nutr (Berl) | pmid:24024579 |
Dengler F et al. | Bicarbonate-dependent transport of acetate and butyrate across the basolateral membrane of sheep rumen epithelium. | 2014 | Acta Physiol (Oxf) | pmid:23927569 |
Yan SF et al. | HDAC inhibitor sodium butyrate augments the MEF2C enhancement of Nampt expression under hypoxia. | 2014 | Curr. Pharm. Des. | pmid:23888946 |
Drees J et al. | Butyrate stimulates the early process of the osteogenic differentiation but inhibits the biomineralization in dental follicle cells (DFCs). | 2014 | Odontology | pmid:23836050 |