butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Salivary Gland Neoplasms D012468 1 associated lipids
Astigmatism D001251 1 associated lipids
Hemorrhoids D006484 2 associated lipids
Lymphoma, AIDS-Related D016483 2 associated lipids
Sarcoma, Avian D001357 2 associated lipids
Dentin, Secondary D003809 2 associated lipids
Colorectal Neoplasms, Hereditary Nonpolyposis D003123 2 associated lipids
Nevus D009506 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Urea Cycle Disorders, Inborn D056806 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Authors Title Published Journal PubMed Link
Rydzyński K and Dalen H Effect of sodium butyrate treatment on the granule morphology, histamine level and elemental content of the bone marrow-derived mast cell. 1994 Folia Histochem. Cytobiol. pmid:8026597
Chen ZX and Breitman TR Tributyrin: a prodrug of butyric acid for potential clinical application in differentiation therapy. 1994 Cancer Res. pmid:8012972
Fariss MW et al. The selective antiproliferative effects of alpha-tocopheryl hemisuccinate and cholesteryl hemisuccinate on murine leukemia cells result from the action of the intact compounds. 1994 Cancer Res. pmid:8012947
Walter KA et al. Studies of recombinant Clostridium acetobutylicum with increased dosages of butyrate formation genes. 1994 Ann. N. Y. Acad. Sci. pmid:8010698
Sadaie MR and Hager GL Induction of developmentally programmed cell death and activation of HIV by sodium butyrate. 1994 Virology pmid:8009866
Ebert PS and Salcman M Differentiation therapy is potentiated by chemotherapy and hyperthermia in human and canine brain tumor cells in vitro. 1994 Neurosurgery pmid:8008163
Mullany P et al. Genes encoding homologues of three consecutive enzymes in the butyrate/butanol-producing pathway of Clostridium acetobutylicum are clustered on the Clostridium difficile chromosome. 1994 FEMS Microbiol. Lett. pmid:8001771
Mannon PJ et al. Characterization of a Y1-preferring NPY/PYY receptor in HT-29 cells. 1994 Am. J. Physiol. pmid:7977753
Bartram HP et al. Antagonistic effects of deoxycholic acid and butyrate on epithelial cell proliferation in the proximal and distal human colon. 1994 Z Gastroenterol pmid:7975774
Fanti L et al. Carnitine suppression of position-effect variegation in Drosophila melanogaster. 1994 Mol. Gen. Genet. pmid:7969027
Sun SH et al. Effects of sodium butyrate on the transfer of arachidonic acid to phosphatidylcholine in a clonal oligodendrocyte cell line (CB-II). 1994 Lipids pmid:7968267
Coleman WB et al. Development of dexamethasone-inducible tyrosine aminotransferase activity in WB-F344 rat liver epithelial stemlike cells cultured in the presence of sodium butyrate. 1994 J. Cell. Physiol. pmid:7962128
Chang AE Perspectives on interleukin-2 immunotherapy for colon cancer. 1994 Gastroenterology pmid:7958708
Perrin P et al. An interleukin 2/sodium butyrate combination as immunotherapy for rat colon cancer peritoneal carcinomatosis. 1994 Gastroenterology pmid:7958681
Almouzni G et al. Histone acetylation influences both gene expression and development of Xenopus laevis. 1994 Dev. Biol. pmid:7958429
Tang MJ et al. Expression and regulation of Na, K-ATPase in primary culture of proximal tubule cells. 1994 Chin J Physiol pmid:7956509
Schaffer JE and Lodish HF Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein. 1994 Cell pmid:7954810
Ohannesian DW et al. Concomitant increases in galectin-1 and its glycoconjugate ligands (carcinoembryonic antigen, lamp-1, and lamp-2) in cultured human colon carcinoma cells by sodium butyrate. 1994 Cancer Res. pmid:7954433
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Nishii Y et al. n-Butyrate enhances induction of thyroid hormone-responsive nuclear protein. 1993 Endocr. J. pmid:7951517
Safaya S et al. Augmentation of gamma-globin gene promoter activity by carboxylic acids and components of the human beta-globin locus control region. 1994 Blood pmid:7949149
Gupta S et al. Butyrate synchronization of hepatocytes: modulation of cycling and cell cycle regulated gene expression. 1994 Growth Factors pmid:7946406
Critchfield JW et al. Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-glycoprotein as a putative mechanism. 1994 Biochem. Pharmacol. pmid:7945444
Bode BP and Souba WW Modulation of cellular proliferation alters glutamine transport and metabolism in human hepatoma cells. 1994 Ann. Surg. pmid:7944654
Pomponi MG and Neri G Butyrate and acetyl-carnitine inhibit the cytogenetic expression of the fragile X in vitro. 1994 Am. J. Med. Genet. pmid:7943015
Swarovsky B et al. Sodium butyrate induces neuroendocrine cytodifferentiation in the insulinoma cell line RINm5F. 1994 Pancreas pmid:7937695
Wu QH et al. Replication of human cytomegalovirus in cells deficient in beta 2-microglobulin gene expression. 1994 J. Gen. Virol. pmid:7931162
Schroy PC et al. Growth and intestinal differentiation are independently regulated in HT29 colon cancer cells. 1994 J. Cell. Physiol. pmid:7929596
Katsarov V et al. Effect of the butyric short-chain fatty acid on the intracranial pressure and EEG of rabbits. 1993 Folia Med (Plovdiv) pmid:7927056
Tang MJ and Tannen RL Metabolic substrates alter attachment and differentiated functions of proximal tubule cell culture. 1994 J. Am. Soc. Nephrol. pmid:7919143
Papazafiri P et al. Expression of muscle calsequestrin in epithelial HeLa cells: distribution and functional role. 1994 Biochim. Biophys. Acta pmid:7918667
Ho SB et al. Stable differentiation of a human colon adenocarcinoma cell line by sodium butyrate is associated with multidrug resistance. 1994 J. Cell. Physiol. pmid:7913708
Antoni BA et al. NF-kappa B-dependent and -independent pathways of HIV activation in a chronically infected T cell line. 1994 Virology pmid:7913275
Arcus AC et al. Studies with the autotransplanted ovine pancreas: glucagon and insulin secretion. 1976 Aust. J. Biol. Sci. pmid:791227
Morrow CS et al. Reversible transcriptional activation of mdr1 by sodium butyrate treatment of human colon cancer cells. 1994 J. Biol. Chem. pmid:7908296
Corra S et al. Modification of antigen expression in human and hamster pancreatic cancer cell lines induced by sodium butyrate. 1993 Teratog., Carcinog. Mutagen. pmid:7905674
D'Argenio G et al. Butyrate, mesalamine, and factor XIII in experimental colitis in the rat: effects on transglutaminase activity. 1994 Gastroenterology pmid:7905450
Filippovich I et al. Butyrate induced apoptosis in lymphoid cells preceded by transient over-expression of HSP70 mRNA. 1994 Biochem. Biophys. Res. Commun. pmid:7904816
Holtenius K and Hydbring E Somatostatin inhibits butyrate-induced insulin secretion in sheep. 1993 Acta Vet Scand Suppl pmid:7901983
Soneoka Y et al. A transient three-plasmid expression system for the production of high titer retroviral vectors. 1995 Nucleic Acids Res. pmid:7899083
Annunziato AT et al. Relationship between methylation and acetylation of arginine-rich histones in cycling and arrested HeLa cells. 1995 Biochemistry pmid:7893706
Finnie IA et al. Colonic mucin synthesis is increased by sodium butyrate. 1995 Gut pmid:7890244
Roediger WE and Millard S Selective inhibition of fatty acid oxidation in colonocytes by ibuprofen: a cause of colitis? 1995 Gut pmid:7890237
Tune BM and Hsu CY Toxicity of cephalosporins to fatty acid metabolism in rabbit renal cortical mitochondria. 1995 Biochem. Pharmacol. pmid:7887988
Higgins PJ et al. Cell-shape-dependent modulation of p52(PAI-1) gene expression involves a secondary response pathway. 1995 Biochem. J. pmid:7887903
Stein J et al. Mercaptopropionate inhibits butyrate uptake in isolated apical membrane vesicles of the rat distal colon. 1995 Gastroenterology pmid:7875469
Saito H et al. Changes of antigen expression on human hepatoma cell lines caused by sodium butyrate, a differentiation inducer. 1994 J. Gastroenterol. pmid:7874268
Dang J et al. Sodium butyrate inhibits expression of urokinase and its receptor mRNAs at both transcription and post-transcription levels in colon cancer cells. 1995 FEBS Lett. pmid:7867787
Blouin MJ et al. Specialization switch in differentiating embryonic rat liver progenitor cells in response to sodium butyrate. 1995 Exp. Cell Res. pmid:7867717
Tang SJ et al. Analysis of c-fos expression in the butyrate-induced F-98 glioma cell differentiation. 1995 Biochem. J. pmid:7864828