butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Aviram A et al. | Comparison between the effect of butyric acid and its prodrug pivaloyloxymethylbutyrate on histones hyperacetylation in an HL-60 leukemic cell line. | 1994 | Int. J. Cancer | pmid:8119779 |
| Krief S et al. | Transcriptional modulation by n-butyric acid of beta 1-, beta 2-, and beta 3-adrenergic receptor balance in 3T3-F442A adipocytes. | 1994 | J. Biol. Chem. | pmid:8120022 |
| Fedotov VP et al. | [The possible participation of gap junctions in the realization of the effects of stimulators of secretory processes in the hypophysis]. | 1993 | Biull Eksp Biol Med | pmid:8123822 |
| Cann IK et al. | Effects of 3 chemical treatments on in vitro fermentation of rice straw by mixed rumen microbes in the presence or absence of anaerobic rumen fungi. | 1994 | Reprod. Nutr. Dev. | pmid:8129842 |
| Morand C et al. | Importance of the modulation of glycolysis in the control of lactate metabolism by fatty acids in isolated hepatocytes from fed rats. | 1994 | Arch. Biochem. Biophys. | pmid:8135535 |
| Lee S et al. | 1,25-Dihydroxyvitamin D3 and pancreatic beta-cell function: vitamin D receptors, gene expression, and insulin secretion. | 1994 | Endocrinology | pmid:8137721 |
| Honda J et al. | Spectroscopic observation of the intramolecular electron transfer in the photoactivation processes of nitrile hydratase. | 1994 | Biochemistry | pmid:8142355 |
| Boffa LC et al. | Selective hypermethylation of transcribed nucleosomal DNA by sodium butyrate. | 1994 | Exp. Cell Res. | pmid:8143791 |
| Higgins PJ and Lipkin M | Expression of plasminogen activator inhibitor type 1 (PAI-1) by HT-29di human large bowel carcinoma cells is modulated as a function of epithelial differentiation. | 1994 | Cancer Lett. | pmid:8149346 |
| Schlake T et al. | Gene expression within a chromatin domain: the role of core histone hyperacetylation. | 1994 | Biochemistry | pmid:8155635 |
| Duman RS et al. | Induction of beta 2-adrenergic receptor mRNA and ligand binding in HeLa cells. | 1994 | J. Recept. Res. | pmid:8158578 |
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| Ogryzko VV et al. | Dissociation of retinoblastoma gene protein hyperphosphorylation and commitment to enter S phase. | 1994 | J. Virol. | pmid:8189510 |
| Barratt MJ et al. | Mitogen-stimulated phosphorylation of histone H3 is targeted to a small hyperacetylation-sensitive fraction. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8197135 |
| Sheikh MS et al. | Expression of estrogen receptors in estrogen receptor-negative human breast carcinoma cells: modulation of epidermal growth factor-receptor (EGF-R) and transforming growth factor alpha (TGF alpha) gene expression. | 1994 | J. Cell. Biochem. | pmid:8200909 |
| Cairns SP and Dulhunty AF | Beta-adrenoceptor activation shows high-frequency fatigue in skeletal muscle fibers of the rat. | 1994 | Am. J. Physiol. | pmid:8203484 |
| Gürtler H et al. | Acute metabolic and hormonal effects of intravenously administered sodium n-butyrate in untreated and alloxan-diabetic sheep. | 1993 | Zentralbl Veterinarmed A | pmid:8212952 |
| Nakai T et al. | Changes in CA125 release and surface expression caused by drugs in uterine cervix adenocarcinoma cells. | 1993 | Ann Nucl Med | pmid:8217487 |
| Gope R and Gope ML | Effect of sodium butyrate on the expression of retinoblastoma (RB1) and P53 gene and phosphorylation of retinoblastoma protein in human colon tumor cell line HT29. | 1993 | Cell. Mol. Biol. (Noisy-le-grand) | pmid:8220069 |
| Musk SR and Johnson IT | Allyl isothiocyanate is selectively toxic to transformed cells of the human colorectal tumour line HT29. | 1993 | Carcinogenesis | pmid:8222057 |
| Dimitrov S et al. | Chromatin transitions during early Xenopus embryogenesis: changes in histone H4 acetylation and in linker histone type. | 1993 | Dev. Biol. | pmid:8224538 |
| Piñeiro M et al. | Transcription of mononucleosomal particles acetylated in the presence of n-butyrate. | 1993 | Mol. Biol. Rep. | pmid:8232292 |
| Finnie IA et al. | Ileal and colonic epithelial metabolism in quiescent ulcerative colitis: increased glutamine metabolism in distal colon but no defect in butyrate metabolism. | 1993 | Gut | pmid:8244143 |
| Roediger WE | Colonic epithelial metabolism in ulcerative colitis. | 1993 | Gut | pmid:8244158 |
| Halvorsen YD et al. | Vasodilation of rat retinal microvessels induced by monobutyrin. Dysregulation in diabetes. | 1993 | J. Clin. Invest. | pmid:8254042 |
| Planchon P et al. | Differential elimination of synthetic butyric triglycerides in vivo: a pharmacokinetic study. | 1993 | J Pharm Sci | pmid:8254490 |
| Perry CA et al. | Parental nucleosomes segregated to newly replicated chromatin are underacetylated relative to those assembled de novo. | 1993 | Biochemistry | pmid:8257695 |
| Karuri AR et al. | Selective cellular acidification and toxicity of weak organic acids in an acidic microenvironment. | 1993 | Br. J. Cancer | pmid:8260358 |
| Stark AH and Madar Z | In vitro production of short-chain fatty acids by bacterial fermentation of dietary fiber compared with effects of those fibers on hepatic sterol synthesis in rats. | 1993 | J. Nutr. | pmid:8263612 |
| Fürll M et al. | [Hormonal reactions in fattening bulls and cows during a three-week butyric acid exposure]. | 1993 | Berl. Munch. Tierarztl. Wochenschr. | pmid:8267563 |
| Fürll M et al. | [Effect of a three-week butyric acid exposure on the mineral metabolism and the skeletal system in cattle]. | 1993 | Berl. Munch. Tierarztl. Wochenschr. | pmid:8267564 |
| Haag MM et al. | Reverse transformation and genome exposure in the C6 glial tumor cell line. | 1994 | Cancer Invest. | pmid:8281464 |
| Hague A et al. | Escape from negative regulation of growth by transforming growth factor beta and from the induction of apoptosis by the dietary agent sodium butyrate may be important in colorectal carcinogenesis. | 1993 | Cancer Metastasis Rev. | pmid:8281610 |
| Sperker B et al. | The expression of human plasma cholesteryl-ester-transfer protein in HepG2 cells is induced by sodium butyrate. Quantification of low mRNA levels by polymerase chain reaction. | 1993 | Eur. J. Biochem. | pmid:8281947 |
| Roediger WE et al. | Sulphide impairment of substrate oxidation in rat colonocytes: a biochemical basis for ulcerative colitis? | 1993 | Clin. Sci. | pmid:8287651 |
| Iwami K and Moriyama T | Effects of short chain fatty acid, sodium butyrate, on osteoblastic cells and osteoclastic cells. | 1993 | Int. J. Biochem. | pmid:8288032 |
| Carraro S et al. | [Influence of sodium butyrate intake on murine colonic carcinogenesis]. | 1993 | Medicina (B Aires) | pmid:8295530 |
| Dong QG et al. | Isolation of a mitomycin-resistant human lung adenocarcinoma cell subline to investigate the modulation by sodium butyrate of cell growth and drug resistance. | 1993 | Anticancer Drugs | pmid:8298162 |
| Fernandez-Mejia C and Davidson MB | Effect of sodium butyrate on glucose transport and glucose-phosphorylating enzymes in RIN-m5F cells. | 1993 | Pancreas | pmid:8302795 |
| Steinhart AH et al. | Treatment of refractory ulcerative proctosigmoiditis with butyrate enemas. | 1994 | Am. J. Gastroenterol. | pmid:8304299 |
| Yabushita H and Sartorelli AC | Effects of sodium butyrate, dimethylsulfoxide and dibutyryl cAMP on the poorly differentiated ovarian adenocarcinoma cell line AMOC-2. | 1993 | Oncol. Res. | pmid:8305743 |
| Chapman MA et al. | Butyrate oxidation is impaired in the colonic mucosa of sufferers of quiescent ulcerative colitis. | 1994 | Gut | pmid:8307454 |
| Bartram HP et al. | Proliferation of human colonic mucosa as an intermediate biomarker of carcinogenesis: effects of butyrate, deoxycholate, calcium, ammonia, and pH. | 1993 | Cancer Res. | pmid:8324739 |
| Souleimani A and Asselin C | Regulation of c-myc expression by sodium butyrate in the colon carcinoma cell line Caco-2. | 1993 | FEBS Lett. | pmid:8325387 |
| Komatsu N et al. | Establishment and characterization of an erythropoietin-dependent subline, UT-7/Epo, derived from human leukemia cell line, UT-7. | 1993 | Blood | pmid:8329702 |
| Cremer JE et al. | The influence of portocaval anastomosis on the metabolism of labelled octanoate, butyrate and leucine in rat brain. | 1977 | J. Neurochem. | pmid:833594 |
| Murray NR et al. | Protein kinase C isotypes in human erythroleukemia (K562) cell proliferation and differentiation. Evidence that beta II protein kinase C is required for proliferation. | 1993 | J. Biol. Chem. | pmid:8340409 |
| Taggart M and Wray S | Simultaneous measurement of intracellular pH and contraction in uterine smooth muscle. | 1993 | Pflugers Arch. | pmid:8351202 |
| Mollinedo F et al. | Differences in expression of transcription factor AP-1 in human promyelocytic HL-60 cells during differentiation towards macrophages versus granulocytes. | 1993 | Biochem. J. | pmid:8363564 |