butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Böhm L et al. | Influence of histone acetylation on the modification of cytoplasmic and nuclear proteins by ADP-ribosylation in response to free radicals. | 1997 | Biochim. Biophys. Acta | pmid:9101708 |
Rolandelli RH et al. | Intravenous butyrate and healing of colonic anastomoses in the rat. | 1997 | Dis. Colon Rectum | pmid:9102264 |
Bingham S | Meat, starch and non-starch polysaccharides, are epidemiological and experimental findings consistent with acquired genetic alterations in sporadic colorectal cancer? | 1997 | Cancer Lett. | pmid:9103247 |
Marchetti C et al. | Deoxycholic acid and SCFA-induced apoptosis in the human tumor cell-line HT-29 and possible mechanisms. | 1997 | Cancer Lett. | pmid:9103263 |
Wang MC et al. | Protein tyrosine phosphatase-dependent activation of beta-globin and delta-aminolevulinic acid synthase genes in the camptothecin-induced IW32 erythroleukemia cell differentiation. | 1997 | Mol. Pharmacol. | pmid:9106619 |
Jasinskas A et al. | Turnover of histone acetyl groups during sea urchin early development is not required for histone, heat shock and actin gene transcription. | 1997 | Biochim. Biophys. Acta | pmid:9116030 |
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Siavoshian S et al. | Butyrate stimulates cyclin D and p21 and inhibits cyclin-dependent kinase 2 expression in HT-29 colonic epithelial cells. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9125124 |
Autrup H et al. | Effect of various chemicals on the metabolism of benzo(a)pyrene by cultured rat colon. | 1977 | Chem. Biol. Interact. | pmid:912816 |
Pöllänen MT et al. | Bacterial metabolites sodium butyrate and propionate inhibit epithelial cell growth in vitro. | 1997 | J. Periodont. Res. | pmid:9138199 |
Mariadason JM et al. | Effect of short-chain fatty acids on paracellular permeability in Caco-2 intestinal epithelium model. | 1997 | Am. J. Physiol. | pmid:9142899 |
Benard O and Balasubramanian KA | Modulation of glutathione level during butyrate-induced differentiation in human colon derived HT-29 cells. | 1997 | Mol. Cell. Biochem. | pmid:9144324 |
Scheppach W et al. | Effects of short-chain fatty acids on the inflamed colonic mucosa. | 1997 | Scand. J. Gastroenterol. Suppl. | pmid:9145448 |
Garcia-Villalba P et al. | Histone acetylation influences thyroid hormone and retinoic acid-mediated gene expression. | 1997 | DNA Cell Biol. | pmid:9150429 |
Chen WY et al. | Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9159154 |
Kim J et al. | Studies on the effects of selenium on rumen microbial fermentation in vitro. | 1997 | Biol Trace Elem Res | pmid:9164665 |
Napolitano LM | Dose-response effect of butyrate. | 1997 May-Jun | JPEN J Parenter Enteral Nutr | pmid:9168372 |
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Dimitrov SI and Wolffe AP | Fine resolution of histones by two-dimensional polyacrylamide gel electrophoresis: developmental implications. | 1997 | Methods | pmid:9169195 |
Ou HC et al. | Sodium butyrate decreases histamine-stimulated calcium mobilization in C6 glioma cells. | 1997 | Neuroreport | pmid:9172138 |
Kashanchi F et al. | Rapid and sensitive detection of cell-associated HIV-1 in latently infected cell lines and in patient cells using sodium-n-butyrate induction and RT-PCR. | 1997 | J. Med. Virol. | pmid:9179766 |
Graham ME et al. | Modification of annexin II expression in PC12 cell lines does not affect Ca(2+)-dependent exocytosis. | 1997 | Mol. Biol. Cell | pmid:9188096 |
Wallace KK et al. | In vivo and in vitro effects of thiolactomycin on fatty acid biosynthesis in Streptomyces collinus. | 1997 | J. Bacteriol. | pmid:9190803 |
Otonkoski T et al. | Nicotinamide and sodium butyrate for the induction of fetal porcine beta-cell differentiation prior to transplantation. | 1997 | Transplant. Proc. | pmid:9193518 |
Edward M et al. | Effect of retinoic acid on melanoma cell-derived factor stimulation of fibroblast glycosaminoglycan synthesis. | 1997 | Melanoma Res. | pmid:9195557 |
Marchetti MC et al. | Possible mechanisms involved in apoptosis of colon tumor cell lines induced by deoxycholic acid, short-chain fatty acids, and their mixtures. | 1997 | Nutr Cancer | pmid:9200153 |
Gossett RE et al. | Expression of fatty acyl-CoA binding proteins in colon cells: response to butyrate and transformation. | 1997 | Lipids | pmid:9208385 |
Nakajima T et al. | The effect of carnitine on ketogenesis in perfused livers from juvenile visceral steatosis mice with systemic carnitine deficiency. | 1997 | Pediatr. Res. | pmid:9212045 |
Singh B et al. | Butyrate can act as a stimulator of growth or inducer of apoptosis in human colonic epithelial cell lines depending on the presence of alternative energy sources. | 1997 | Carcinogenesis | pmid:9214612 |
McBain JA et al. | Apoptotic death in adenocarcinoma cell lines induced by butyrate and other histone deacetylase inhibitors. | 1997 | Biochem. Pharmacol. | pmid:9214697 |
Alaoui-Ismaïli O et al. | Odor hedonics: connection with emotional response estimated by autonomic parameters. | 1997 | Chem. Senses | pmid:9218136 |
Ebert SN et al. | Adrenergic differentiation potential in PC12 cells: influence of sodium butyrate and dexamethasone. | 1997 | Brain Res. Mol. Brain Res. | pmid:9221898 |
Atkins KB et al. | Stimulation of osteopontin mRNA expression in HL-60 cells is independent of differentiation. | 1997 | Arch. Biochem. Biophys. | pmid:9224725 |
Erickson KD and Martin JM | Early detection of the lytic LMP-1 protein in EBV-infected B-cells suggests its presence in the virion. | 1997 | Virology | pmid:9234942 |
Millais AJ et al. | The biotransformation of t-butylacetonitrile and its boron-containing analogue trimethylamine-cyanoborane by Brevibacterium R312. | 1997 | Arch. Microbiol. | pmid:9238109 |
Ferry AE et al. | Globin gene silencing in primary erythroid cultures. An inhibitory role for interleukin-6. | 1997 | J. Biol. Chem. | pmid:9242673 |
Siavoshian S et al. | Comparison of the effect of different short chain fatty acids on the growth and differentiation of human colonic carcinoma cell lines in vitro. | 1997 | Cell Biol. Int. | pmid:9243803 |
Kaeffer B et al. | Treatment of rat proximal and distal colonic cells with sodium orthovanadate enhances their adhesion and survival in primary culture. | 1997 | Cell Biol. Int. | pmid:9243806 |
Jacobasch G and Jacobasch KH | [Molecular etiology of colorectal carcinogenesis, clinical manifestations and therapy]. | 1997 | Z Arztl Fortbild Qualitatssich | pmid:9244653 |
Qin S and Yamamura H | Up-regulation of Syk activity during HL60 cell differentiation into granulocyte but not into monocyte/macrophage-lineage. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9245716 |
Navarro JM et al. | Differentiation of BCS-TC2 human colon adenocarcinoma cells by sodium butyrate: increase in 5'-nucleotidase activity. | 1997 | Eur. J. Clin. Invest. | pmid:9263751 |
Tai G et al. | Different effects of cyclic AMP and butyrate on eosinophilic differentiation, apoptosis and bcl-2 expression of a human eosinophilic leukemia cell line, EoL-1. | 1996 | Hematol Oncol | pmid:9267464 |
Nakano K et al. | Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line. | 1997 | J. Biol. Chem. | pmid:9268365 |
Xiao H et al. | Sodium butyrate induces NIH3T3 cells to senescence-like state and enhances promoter activity of p21WAF/CIP1 in p53-independent manner. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9268733 |
Simon B et al. | Transient transcriptional activation of gastrin during sodium butyrate-induced differentiation of islet cells. | 1997 | Regul. Pept. | pmid:9272626 |
Humbert G et al. | Method for the measurement of lipase activity in milk. | 1997 | J. Dairy Res. | pmid:9275261 |
De Visser H et al. | Nutrient fluxes in splanchnic tissue of dairy cows: influence of grass quality. | 1997 | J. Dairy Sci. | pmid:9276806 |
Kenyon E et al. | Apical and basolateral membrane mechanisms that regulate pHi in bovine retinal pigment epithelium. | 1997 | Am. J. Physiol. | pmid:9277343 |
Chen ZJ and Pikaard CS | Epigenetic silencing of RNA polymerase I transcription: a role for DNA methylation and histone modification in nucleolar dominance. | 1997 | Genes Dev. | pmid:9284051 |