butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Zhang L et al. | Sodium Butyrate Protects -Against High Fat Diet-Induced Cardiac Dysfunction and Metabolic Disorders in Type II Diabetic Mice. | 2017 | J. Cell. Biochem. | pmid:28109123 |
Xu J et al. | Effects of Early Intervention with Sodium Butyrate on Gut Microbiota and the Expression of Inflammatory Cytokines in Neonatal Piglets. | 2016 | PLoS ONE | pmid:27611998 |
Kotantaki P and Mosialos G | The expression of tumor suppressor gene Cyld is upregulated by histone deacetylace inhibitors in human hepatocellular carcinoma cell lines. | 2016 | Cell Biochem. Funct. | pmid:27570065 |
Ãvila M et al. | Application of high pressure processing for controlling Clostridium tyrobutyricum and late blowing defect on semi-hard cheese. | 2016 | Food Microbiol. | pmid:27554159 |
Bai G et al. | Dietary Casein and Soy Protein Isolate Modulate the Effects of Raffinose and Fructooligosaccharides on the Composition and Fermentation of Gut Microbiota in Rats. | 2016 | J. Food Sci. | pmid:27434756 |
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Venkataraman A et al. | Variable responses of human microbiomes to dietary supplementation with resistant starch. | 2016 | Microbiome | pmid:27357127 |
Liang B and Fang J | Postnatal Isoflurane Exposure Induces Cognitive Impairment and Abnormal Histone Acetylation of Glutamatergic Systems in the Hippocampus of Adolescent Rats. | 2016 | J. Mol. Neurosci. | pmid:27307148 |
Lee J et al. | Deciphering Clostridium tyrobutyricum Metabolism Based on the Whole-Genome Sequence and Proteome Analyses. | 2016 | MBio | pmid:27302759 |
Carretta MD et al. | Butyric acid stimulates bovine neutrophil functions and potentiates the effect of platelet activating factor. | 2016 | Vet. Immunol. Immunopathol. | pmid:27288853 |
Rephaeli A et al. | Bi-functional prodrugs of 5-aminolevulinic acid and butyric acid increase erythropoiesis in anemic mice in an erythropoietin-independent manner. | 2016 | Eur J Pharm Sci | pmid:27283485 |
Moreno FS et al. | Nutritional Epigenetics and the Prevention of Hepatocellular Carcinoma with Bioactive Food Constituents. | 2016 | Nutr Cancer | pmid:27266713 |
Aguilar EC et al. | Oral butyrate reduces oxidative stress in atherosclerotic lesion sites by a mechanism involving NADPH oxidase down-regulation in endothelial cells. | 2016 | J. Nutr. Biochem. | pmid:27261536 |
Zeng J et al. | Autophagy regulates biliary differentiation of hepatic progenitor cells through Notch1 signaling pathway. | 2016 | Cell Cycle | pmid:27259983 |
Sun J et al. | Antidepressant-like effects of sodium butyrate and its possible mechanisms of action in mice exposed to chronic unpredictable mild stress. | 2016 | Neurosci. Lett. | pmid:26957230 |
Su CL et al. | Epigenetic regulation of BDNF in the learned helplessness-induced animal model of depression. | 2016 | J Psychiatr Res | pmid:26921875 |
Tanaka S et al. | Relationship of Enhanced Butyrate Production by Colonic Butyrate-Producing Bacteria to Immunomodulatory Effects in Normal Mice Fed an Insoluble Fraction of Brassica rapa L. | 2016 | Appl. Environ. Microbiol. | pmid:26921420 |
Donovan JD et al. | Volatile Retention and Morphological Properties of Microencapsulated Tributyrin Varied by Wall Material and Drying Method. | 2016 | J. Food Sci. | pmid:26878682 |
Wang ZT et al. | Histone deacetylase inhibitors suppress mutant p53 transcription via HDAC8/YY1 signals in triple negative breast cancer cells. | 2016 | Cell. Signal. | pmid:26876786 |
Zounr RA et al. | Improved Gas Chromatographic Determination of Guanidino Compounds Using Isovaleroylacetone and Ethyl Chloroformate as Derivatizing Reagents. | 2016 | Anal Sci | pmid:26860556 |
Wang J et al. | Therapeutic Effect of Histone Deacetylase Inhibitor, Sodium Butyrate, on Allergic Rhinitis In Vivo. | 2016 | DNA Cell Biol. | pmid:26859163 |
Ziegler K et al. | Butyric acid increases transepithelial transport of ferulic acid through upregulation of the monocarboxylate transporters SLC16A1 (MCT1) and SLC16A3 (MCT4). | 2016 | Arch. Biochem. Biophys. | pmid:26854723 |
Tao Y et al. | Production of Butyrate from Lactate by a Newly Isolated Clostridium sp. BPY5. | 2016 | Appl. Biochem. Biotechnol. | pmid:26842597 |
Zhu P et al. | [Effect and mechanism of inhibition of lipopolysaccharide-induced pulmonary fibrosis by butyric acid]. | 2016 | Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | pmid:26805528 |
Sayed M et al. | Selective oxidation of trimethylolpropane to 2,2-bis(hydroxymethyl)butyric acid using growing cells of Corynebacterium sp. ATCC 21245. | 2016 | J. Biotechnol. | pmid:26804932 |
Zhang J et al. | Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for Apoptosis. | 2016 | PLoS ONE | pmid:26784903 |
Kratsman N et al. | Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model. | 2016 | Neuropharmacology | pmid:26577018 |
Heidor R et al. | The chemopreventive activity of butyrate-containing structured lipids in experimental rat hepatocarcinogenesis. | 2016 | Mol Nutr Food Res | pmid:26548572 |
Cueno ME et al. | Periodontal disease level-butyric acid amounts locally administered in the rat gingival mucosa induce ER stress in the systemic blood. | 2016 | Microb. Pathog. | pmid:26541671 |
Sergeev E et al. | Non-equivalence of Key Positively Charged Residues of the Free Fatty Acid 2 Receptor in the Recognition and Function of Agonist Versus Antagonist Ligands. | 2016 | J. Biol. Chem. | pmid:26518871 |
Curren J et al. | Identification and quantification of nuisance odors at a trash transfer station. | 2016 | Waste Manag | pmid:27692531 |
Silva FT et al. | Replacement of sugars to hydrogen production by Rhodobacter capsulatus using dark fermentation effluent as substrate. | 2016 | Bioresour. Technol. | pmid:26476167 |
Contreras-Leal E et al. | Histone deacetylase inhibitors promote the expression of ATP2A3 gene in breast cancer cell lines. | 2016 | Mol. Carcinog. | pmid:26331238 |
Han M et al. | Dietary grape seed proanthocyanidins (GSPs) improve weaned intestinal microbiota and mucosal barrier using a piglet model. | 2016 | Oncotarget | pmid:27880936 |
Rumpagaporn P et al. | Elevated propionate and butyrate in fecal ferments of hydrolysates generated by oxalic acid treatment of corn bran arabinoxylan. | 2016 | Food Funct | pmid:27841429 |
Karthikeyan OP et al. | Hydrolysis-acidogenesis of food waste in solid-liquid-separating continuous stirred tank reactor (SLS-CSTR) for volatile organic acid production. | 2016 | Bioresour. Technol. | pmid:26512860 |
Xing X et al. | Sodium butyrate protects against oxidative stress in HepG2 cells through modulating Nrf2 pathway and mitochondrial function. | 2016 | J. Physiol. Biochem. | pmid:28600747 |
Youn YS et al. | Molecular tuning of amino acids to form two-dimensional molecular networks driven by conformational preorganization. | 2016 | Chem. Commun. (Camb.) | pmid:27858018 |
MartÃn Juárez J et al. | Saccharification of microalgae biomass obtained from wastewater treatment by enzymatic hydrolysis. Effect of alkaline-peroxide pretreatment. | 2016 | Bioresour. Technol. | pmid:27372005 |
Khan S and Jena G | Sodium butyrate reduces insulin-resistance, fat accumulation and dyslipidemia in type-2 diabetic rat: A comparative study with metformin. | 2016 | Chem. Biol. Interact. | pmid:27270450 |
Zhang Z et al. | O-Linked N-Acetylglucosamine (O-GlcNAc) Transferase and O-GlcNAcase Interact with Mi2β Protein at the Aγ-Globin Promoter. | 2016 | J. Biol. Chem. | pmid:27231347 |
Grimaldi R et al. | Fermentation properties and potential prebiotic activity of Bimuno® galacto-oligosaccharide (65 % galacto-oligosaccharide content) on in vitro gut microbiota parameters. | 2016 | Br. J. Nutr. | pmid:27267934 |
Kulcsár A et al. | Effects of butyrate on the insulin homeostasis of chickens kept on maize- or wheat-based diets. | 2016 | Acta Vet. Hung. | pmid:27993103 |
Bencsik R et al. | Improved transgene expression in doxycycline-inducible embryonic stem cells by repeated chemical selection or cell sorting. | 2016 | Stem Cell Res | pmid:27591479 |
Han R et al. | Sodium Butyrate Upregulates miR-203 Expression to Exert Anti-Proliferation Effect on Colorectal Cancer Cells. | 2016 | Cell. Physiol. Biochem. | pmid:27771718 |
Polak U et al. | Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming. | 2016 | Stem Cells Dev. | pmid:27615158 |
Chen WS et al. | Effects of histone deacetylase inhibitor sodium butyrate on heroin seeking behavior in the nucleus accumbens in rats. | 2016 | Brain Res. | pmid:27742468 |
Miao W et al. | Sodium Butyrate Promotes Reassembly of Tight Junctions in Caco-2 Monolayers Involving Inhibition of MLCK/MLC2 Pathway and Phosphorylation of PKCβ2. | 2016 | Int J Mol Sci | pmid:27735862 |
Ain QU et al. | Analysis of Differential Efficacy and Affinity of GABA (α1/α2) Selective Modulators. | 2016 | Mol. Pharm. | pmid:27704838 |