butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Walia K et al. | Effect of feeding sodium butyrate in the late finishing period on Salmonella carriage, seroprevalence, and growth of finishing pigs. | 2016 | Prev. Vet. Med. | pmid:27544256 |
Otto A et al. | The protein inventory of Clostridium difficile grown in complex and minimal medium. | 2016 | Proteomics Clin Appl | pmid:27511832 |
Yin F et al. | Transcriptome Analysis Reveals Regulation of Gene Expression for Lipid Catabolism in Young Broilers by Butyrate Glycerides. | 2016 | PLoS ONE | pmid:27508934 |
Moore JB et al. | The Epigenetic Regulator HDAC1 Modulates Transcription of a Core Cardiogenic Program in Human Cardiac Mesenchymal Stromal Cells Through a p53-Dependent Mechanism. | 2016 | Stem Cells | pmid:27501845 |
Lakhter AJ et al. | Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth. | 2016 | J. Biol. Chem. | pmid:27539851 |
Fialova B et al. | Epigenetic modulation of AR gene expression in prostate cancer DU145 cells with the combination of sodium butyrate and 5'-Aza-2'-deoxycytidine. | 2016 | Oncol. Rep. | pmid:27499010 |
Hou G et al. | Tetracycline removal and effect on the formation and degradation of extracellular polymeric substances and volatile fatty acids in the process of hydrogen fermentation. | 2016 | Bioresour. Technol. | pmid:27070285 |
Kapuvári B et al. | Improved in vivo antitumor effect of a daunorubicin - GnRH-III bioconjugate modified by apoptosis inducing agent butyric acid on colorectal carcinoma bearing mice. | 2016 | Invest New Drugs | pmid:27146514 |
Wu Y et al. | Influence of Butyrate Loaded Clinoptilolite Dietary Supplementation on Growth Performance, Development of Intestine and Antioxidant Capacity in Broiler Chickens. | 2016 | PLoS ONE | pmid:27104860 |
Rivera-Chávez F et al. | Depletion of Butyrate-Producing Clostridia from the Gut Microbiota Drives an Aerobic Luminal Expansion of Salmonella. | 2016 | Cell Host Microbe | pmid:27078066 |
Lazarova DL and Bordonaro M | Vimentin, colon cancer progression and resistance to butyrate and other HDACis. | 2016 | J. Cell. Mol. Med. | pmid:27072512 |
Cang S et al. | Hypoacetylation, hypomethylation, and dephosphorylation of H2B histones and excessive histone deacetylase activity in DU-145 prostate cancer cells. | 2016 | J Hematol Oncol | pmid:26759222 |
Kaczmarek SA et al. | Effect of different doses of coated butyric acid on growth performance and energy utilization in broilers. | 2016 | Poult. Sci. | pmid:26740137 |
Jung JM et al. | Pseudo catalytic transformation of volatile fatty acids into fatty acid methyl esters. | 2016 | Bioresour. Technol. | pmid:26720136 |
Xin F et al. | Strategies for production of butanol and butyl-butyrate through lipase-catalyzed esterification. | 2016 | Bioresour. Technol. | pmid:26710347 |
Cibis KG et al. | Isolation of acetic, propionic and butyric acid-forming bacteria from biogas plants. | 2016 | J. Biotechnol. | pmid:26779817 |
Zhang Y et al. | Monitoring Intracellular pH Change with a Genetically Encoded and Ratiometric Luminescence Sensor in Yeast and Mammalian Cells. | 2016 | Methods Mol. Biol. | pmid:27424899 |
Villain H et al. | HDAC inhibition promotes both initial consolidation and reconsolidation of spatial memory in mice. | 2016 | Sci Rep | pmid:27270584 |
Zhang Q et al. | Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced colitis by a butyrate-producing bacterium. | 2016 | Sci Rep | pmid:27264309 |
Xiong H et al. | Butyrate upregulates endogenous host defense peptides to enhance disease resistance in piglets via histone deacetylase inhibition. | 2016 | Sci Rep | pmid:27230284 |
Anderson NA et al. | Synthesis and determination of absolute configuration of a non-peptidic αvβ6 integrin antagonist for the treatment of idiopathic pulmonary fibrosis. | 2016 | Org. Biomol. Chem. | pmid:27226381 |
Subramanian U et al. | Retinoic acid and sodium butyrate suppress the cardiac expression of hypertrophic markers and proinflammatory mediators in Npr1 gene-disrupted haplotype mice. | 2016 | Physiol. Genomics | pmid:27199456 |
Bastiaansen JA et al. | Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate. | 2016 | Sci Rep | pmid:27150735 |
Vazquez-DeRose J et al. | Hypocretin/orexin antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain. | 2016 | Brain Struct Funct | pmid:25431268 |
Popp D et al. | The alkaloid gramine in the anaerobic digestion process-inhibition and adaptation of the methanogenic community. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27138201 |
Endesfelder D et al. | Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production. | 2016 | Microbiome | pmid:27114075 |
Park MJ and Sohrabji F | The histone deacetylase inhibitor, sodium butyrate, exhibits neuroprotective effects for ischemic stroke in middle-aged female rats. | 2016 | J Neuroinflammation | pmid:27905989 |
Gallo A et al. | Relationships among ensiling, nutritional, fermentative, microbiological traits and contamination in corn silages addressed with partial least squares regression. | 2016 | J. Anim. Sci. | pmid:27898868 |
Estensoro I et al. | Dietary Butyrate Helps to Restore the Intestinal Status of a Marine Teleost (Sparus aurata) Fed Extreme Diets Low in Fish Meal and Fish Oil. | 2016 | PLoS ONE | pmid:27898676 |
Chang MC et al. | Effect of Butyrate on Collagen Expression, Cell Viability, Cell Cycle Progression and Related Proteins Expression of MG-63 Osteoblastic Cells. | 2016 | PLoS ONE | pmid:27893752 |
Zhang T et al. | Sodium Butyrate Reduces Colitogenic Immunoglobulin A-Coated Bacteria and Modifies the Composition of Microbiota in IL-10 Deficient Mice. | 2016 | Nutrients | pmid:27886121 |
Wang Y et al. | A Co-Drug of Butyric Acid Derived from Fermentation Metabolites of the Human Skin Microbiome Stimulates Adipogenic Differentiation of Adipose-Derived Stem Cells: Implications in Tissue Augmentation. | 2017 | J. Invest. Dermatol. | pmid:27498050 |
Machado CF et al. | Conditional Deletion of in Olfactory Sensory Neurons Leads to Olfactory Impairment. | 2017 | J. Neurosci. | pmid:29118104 |
Kobayashi H et al. | Clostridium pabulibutyricum sp. nov., a butyric-acid-producing organism isolated from high-moisture grass silage. | 2017 | Int. J. Syst. Evol. Microbiol. | pmid:29034861 |
Andersen AD et al. | Supplementation with Lactobacillus paracasei or Pediococcus pentosaceus does not prevent diarrhoea in neonatal pigs infected with Escherichia coli F18. | 2017 | Br. J. Nutr. | pmid:28720151 |
Yokoyama Y et al. | Profile of preoperative fecal organic acids closely predicts the incidence of postoperative infectious complications after major hepatectomy with extrahepatic bile duct resection: Importance of fecal acetic acid plus butyric acid minus lactic acid gap. | 2017 | Surgery | pmid:28684159 |
Hofmanová J et al. | Dietary fatty acids specifically modulate phospholipid pattern in colon cells with distinct differentiation capacities. | 2017 | Eur J Nutr | pmid:26983609 |
Górka P et al. | Effect of butyrate infusion into the rumen on butyrate flow to the duodenum, selected gene expression in the duodenum epithelium, and nutrient digestion in sheep. | 2017 | J. Anim. Sci. | pmid:28726987 |
Chang PJ et al. | Effects of the NEDD8-Activating Enzyme Inhibitor MLN4924 on Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus. | 2017 | J. Virol. | pmid:28701396 |
Ito T et al. | Occurrence of the (2R,3S)-Isomer of 2-Amino-3,4-dihydroxybutanoic Acid in the Mushroom Hypsizygus marmoreus. | 2017 | J. Agric. Food Chem. | pmid:28686838 |
Chen X et al. | Sodium butyrate regulates Th17/Treg cell balance to ameliorate uveitis via the Nrf2/HO-1 pathway. | 2017 | Biochem. Pharmacol. | pmid:28684304 |
Olsen S | Effects of ultra-high dilutions of sodium butyrate on viability and gene expression in HEK 293 cells. | 2017 | Homeopathy | pmid:28325222 |
Zhang J et al. | Metabolic engineering of Clostridium tyrobutyricum for n-butanol production from sugarcane juice. | 2017 | Appl. Microbiol. Biotechnol. | pmid:28238080 |
Mathew MP et al. | Glycoengineering of Esterase Activity through Metabolic Flux-Based Modulation of Sialic Acid. | 2017 | Chembiochem | pmid:28218815 |
Maeshige N et al. | Low-Intensity Ultrasound Enhances Histone Acetylation and Inhibition of Interleukin 6 Messenger RNA Expression by the Histone Deacetylase Inhibitor Sodium Butyrate in Fibroblasts. | 2017 | J Ultrasound Med | pmid:28195362 |
Nakazawa A et al. | Evaluation of Adsorption Characteristics of a Fibrous Adsorbent Containing Zwitter-Ionic Functional Group, Targeting Organic Acids. | 2017 | J. UOEH | pmid:28331124 |
Millat T and Winzer K | Mathematical modelling of clostridial acetone-butanol-ethanol fermentation. | 2017 | Appl. Microbiol. Biotechnol. | pmid:28210797 |
Ra CH et al. | Hyper-thermal acid hydrolysis and adsorption treatment of red seaweed, Gelidium amansii for butyric acid production with pH control. | 2017 | Bioprocess Biosyst Eng | pmid:27878375 |
Herrick KJ et al. | Single-dose infusion of sodium butyrate, but not lactose, increases plasma β-hydroxybutyrate and insulin in lactating dairy cows. | 2017 | J. Dairy Sci. | pmid:27837980 |
Meneses-Reyes JC et al. | Biochemical methane potential of oil-extracted microalgae and glycerol in co-digestion with chicken litter. | 2017 | Bioresour. Technol. | pmid:27864134 |