butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kim JS et al. | High-level scu-PA production by butyrate-treated serum-free culture of recombinant CHO cell line. | Biotechnol. Prog. | pmid:15575713 | |
| González-Pajuelo M et al. | Metabolic engineering of Clostridium acetobutylicum for the industrial production of 1,3-propanediol from glycerol. | Metab. Eng. | pmid:16095939 | |
| Kien CL et al. | Effects of the in vivo supply of butyrate on histone acetylation of cecum in piglets. | JPEN J Parenter Enteral Nutr | pmid:18165447 | |
| Roy MJ et al. | In vitro studies on the inhibition of colon cancer by butyrate and carnitine. | Nutrition | pmid:19619983 | |
| Vester BM et al. | Influence of feeding raw or extruded feline diets on nutrient digestibility and nitrogen metabolism of African wildcats (Felis lybica). | Zoo Biol. | pmid:20095004 | |
| Wang Y et al. | Sodium butyrate-induced apoptosis and ultrastructural changes in MCF-7 breast cancer cells. | Ultrastruct Pathol | pmid:27158913 | |
| Ibrahim MA | Assessment of insulin stability inside diblock copolymer PEG-PLA microspheres. | Sci Pharm | pmid:21179361 | |
| Kim J et al. | Sodium butyrate regulates androgen receptor expression and cell cycle arrest in human prostate cancer cells. | Anticancer Res. | pmid:17970072 | |
| Lee JS and Lee GM | Effect of sodium butyrate on autophagy and apoptosis in Chinese hamster ovary cells. | Biotechnol. Prog. | pmid:22492702 | |
| Doble MA et al. | Luminal regulation of Na(+)/H(+) exchanger gene expression in rat ileal mucosa. | J. Gastrointest. Surg. | pmid:12022991 | |
| Soto-Cruz O et al. | Modeling of growth, lactate consumption, and volatile fatty acid production by Megasphaera elsdenii cultivated in minimal and complex media. | Biotechnol. Prog. | pmid:11934285 | |
| Cai L et al. | Evaluation of zeolite for control of odorants emissions from simulated poultry manure storage. | J. Environ. Qual. | pmid:17215226 | |
| Varel VH et al. | Manure odor potential and Escherichia coli concentrations in manure slurries of feedlot steers fed 40% corn wet distillers grains. | J. Environ. Qual. | pmid:20830936 | |
| Kodama N et al. | Induction of myeloperoxidase and nitrotyrosine formation in a human eosinophilic leukemia cell line, EoL-1. | Cell Biochem. Funct. | pmid:15027099 | |
| Fontanellas A et al. | Hemoglobin content is increased in the human erythroleukemia K562 cell line by a 56.2-kD peptide from uremic plasma. | Am. J. Nephrol. | pmid:15024177 | |
| Jung JW et al. | Augmentation of sodium butyrate-induced apoptosis by p38 MAP kinase inhibition in rat liver epithelial cells. | Antioxid. Redox Signal. | pmid:16356138 | |
| pmid:16166714 | ||||
| Vester BM et al. | Evaluation of nutrient digestibility and fecal characteristics of exotic felids fed horse- or beef-based diets: use of the domestic cat as a model for exotic felids. | Zoo Biol. | pmid:19830746 | |
| Lea MA et al. | Induction of differentiation of colon cancer cells by combined inhibition of kinases and histone deacetylase. | Anticancer Res. | pmid:17465197 | |
| Kien CL et al. | Lactulose feeding lowers cecal densities of clostridia in piglets. | JPEN J Parenter Enteral Nutr | pmid:17463144 | |
| Liamleam W and Annachhatre AP | Electron donors for biological sulfate reduction. | Biotechnol. Adv. | pmid:17572039 | |
| Rahman M et al. | The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPAR-gamma and SIRT-1 expression on a calorie restricted diet. | Oxid Med Cell Longev | pmid:20716918 | |
| Sung YH et al. | Influence of down-regulation of caspase-3 by siRNAs on sodium-butyrate-induced apoptotic cell death of Chinese hamster ovary cells producing thrombopoietin. | Metab. Eng. | pmid:16169764 | |
| Noble R et al. | Olfactory response to mushroom composting emissions as a function of chemical concentration. | J. Environ. Qual. | pmid:11401265 | |
| Nishinaga M et al. | Establishment of a microplate-formatted cell-based immunoassay for rapid analysis of nucleotide excision repair ability in human primary cells. | Photochem. Photobiol. | pmid:22220555 | |
| Lokshina LY et al. | Modeling of anaerobic degradation of solid slaughterhouse waste: inhibition effects of long-chain fatty acids or ammonia. | Appl. Biochem. Biotechnol. | pmid:12794281 | |
| Shahbazfar AA et al. | A survey on anticancer effects of artemisinin, iron, miconazole, and butyric acid on 5637 (bladder cancer) and 4T1 (Breast cancer) cell lines. | J Cancer Res Ther | pmid:25579554 | |
| Loughrin JH et al. | Evaluation of second-generation multistage wastewater treatment system for the removal of malodors from liquid swine waste. | J. Environ. Qual. | pmid:19549951 | |
| Wei ZL et al. | Enhancement of sodium butyrate-induced cell death by hyperthermia in HCT 116 human colorectal cancer cells. | Anticancer Res. | pmid:18630528 | |
| Oh HK et al. | Effect of N-Acetylcystein on butyrate-treated Chinese hamster ovary cells to improve the production of recombinant human interferon-beta-1a. | Biotechnol. Prog. | pmid:16080696 | |
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| Chin HL et al. | Fedbatch operation using Clostridium acetobutylicum suspension culture as biocatalyst for enhancing hydrogen production. | Biotechnol. Prog. | pmid:12675576 | |
| Han L et al. | Sodium butyrate activates erythroid-specific 5-aminolevulinate synthase gene through Sp1 elements at its promoter. | Blood Cells Mol. Dis. | pmid:18555711 | |
| Kim GH et al. | Epigenetic mechanisms of pulmonary hypertension. | Pulm Circ | pmid:22140624 | |
| Taylor AJ and Beck CW | Histone deacetylases are required for amphibian tail and limb regeneration but not development. | Mech. Dev. | pmid:22947425 | |
| Ghosh SK et al. | Short, discontinuous exposure to butyrate effectively sensitizes latently EBV-infected lymphoma cells to nucleoside analogue antiviral agents. | Blood Cells Mol. Dis. | pmid:17161633 | |
| Wang Q et al. | Characterization of monocarboxylate transport in human kidney HK-2 cells. | Mol. Pharm. | pmid:17140255 | |
| Rodriguez J et al. | Enhanced production of monomeric interferon-beta by CHO cells through the control of culture conditions. | Biotechnol. Prog. | pmid:15903237 | |
| Lim SJ et al. | Effect of butyrate on the heregulin/ErbB-mediated proliferation of human colorectal cancer cells. | Mol Med Rep | pmid:21475856 | |
| Hu YC et al. | Enhancement and prolongation of baculovirus-mediated expression in mammalian cells: focuses on strategic infection and feeding. | Biotechnol. Prog. | pmid:12675574 | |
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| Gennari L et al. | Total extract of Beta vulgaris var. cicla seeds versus its purified phenolic components: antioxidant activities and antiproliferative effects against colon cancer cells. | Phytochem Anal | pmid:21337646 | |
| Cenkvári E et al. | Investigations on the effects of Ca-soap of linseed oil on rumen fermentation in sheep and on milk composition of goats. | J Anim Physiol Anim Nutr (Berl) | pmid:15787990 | |
| Joachimiak R et al. | Influence of sodium butyrate on hepatocellular carcinoma (hepG2) and glioblastoma (C6) cell lines in vitro. | Acta Pol Pharm | pmid:18323252 | |
| Fathallah H et al. | Differences in response to fetal hemoglobin induction therapy in beta-thalassemia and sickle cell disease. | Blood Cells Mol. Dis. | pmid:19346141 | |
| Grebenová D et al. | The proteomic study of sodium butyrate antiproliferative/cytodifferentiation effects on K562 cells. | Blood Cells Mol. Dis. | pmid:16978890 | |
| Krokowicz L et al. | Sodium butyrate and short chain fatty acids in prevention of travellers' diarrhoea: a randomized prospective study. | Travel Med Infect Dis | pmid:24063909 | |
| Bartholome AL et al. | Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets. | JPEN J Parenter Enteral Nutr | pmid:15291402 | |
| pmid:11071567 | ||||
| Bijaya G et al. | Synthesis and evaluation of esmolol prodrugs for transdermal delivery. | Drug Deliv | pmid:20553111 |