butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Halgunset J et al. | Butyrate effects on growth, morphology, and fibronectin production in PC-3 prostatic carcinoma cells. | 1988 | Prostate | pmid:2450342 |
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Prasad S and Thakur MK | Age-dependent effects of sodium butyrate and hydrocortisone on acetylation of high mobility group proteins of rat liver. | 1988 | Biochem. Int. | pmid:3365268 |
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Niles RM et al. | The effect of sodium butyrate and retinoic acid on growth and CEA production in a series of human colorectal tumor cell lines representing different states of differentiation. | 1988 | Cancer Invest. | pmid:3365571 |
Leith JT | Modification of the hypoxic fraction of a xenografted human colon tumor by differentiation-inducing agents. | 1988 | J. Natl. Cancer Inst. | pmid:3367384 |
Chan WC et al. | Large granular lymphocyte proliferation: an analysis of T-cell receptor gene arrangement and expression and the effect of in vitro culture with inducing agents. | 1988 | Blood | pmid:2961380 |
Leith JT | Effects of sodium butyrate and 3-aminobenzamide on survival of Chinese hamster HA-1 cells after X irradiation. | 1988 | Radiat. Res. | pmid:3353504 |
Reynier MO et al. | Influence of lipid-rich diets on intestinal cholesterol uptake. | 1988 | Ann. Nutr. Metab. | pmid:3355108 |
Zhang DE and Nelson DA | Histone acetylation in chicken erythrocytes. Rates of deacetylation in immature and mature red blood cells. | 1988 | Biochem. J. | pmid:3355515 |
Lacroix J et al. | In vitro and in vivo activity of 1-aryl-3-(2-chloroethyl) urea derivatives as new antineoplastic agents. | 1988 Jul-Aug | Anticancer Res. | pmid:3052247 |
Tocco DJ et al. | Disposition and metabolism of sodium 4-[(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl]-gamma -oxobenzenebutanoate in rats and dogs. | 1988 Sep-Oct | Drug Metab. Dispos. | pmid:2906591 |
Tocco DJ et al. | The physiological disposition of aerosolized 4-[(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl]-gamma -oxobenzenebutanoate (L-648,051) in rats. | 1988 Sep-Oct | Drug Metab. Dispos. | pmid:2906592 |
Zielke HR et al. | Synthesis of glutamate and glutamine in dibutyryl cyclic AMP-treated astrocytes. | 1989 | Neurosci. Lett. | pmid:2563906 |
Thakur MK and Prasad S | Age-specific methylation of high-mobility-group proteins of the rat liver and its modulation by spermine and sodium butyrate. | 1989 | Mutat. Res. | pmid:2927415 |
Montiel F et al. | Presence of insulin receptors in cultured glial C6 cells. Regulation by butyrate. | 1989 | Biochem. J. | pmid:2930502 |
Denburg JA et al. | Factors influencing basophilic differentiation of HL-60 cells. | 1989 | Int. Arch. Allergy Appl. Immunol. | pmid:2468609 |
Katoh K and Yajima T | Effects of butyric acid and analogues on amylase release from pancreatic segments of sheep and goats. | 1989 | Pflugers Arch. | pmid:2470024 |
Schmidt R et al. | Sodium butyrate selectively antagonizes the inhibitory effect of retinoids on cornified envelope formation in cultured human keratinocytes. | 1989 | J. Cell. Physiol. | pmid:2473084 |
Perrine SP et al. | Sodium butyrate enhances fetal globin gene expression in erythroid progenitors of patients with Hb SS and beta thalassemia. | 1989 | Blood | pmid:2473801 |
Pramanik SK and Bag J | Expression of muscle-specific proteins is necessary to regulate translation of the mRNA for a 40-kDa housekeeping polypeptide in rat L6 cells. | 1989 | Eur. J. Biochem. | pmid:2473901 |
Myers DE et al. | The effects of aromatic and aliphatic maleimide crosslinkers on anti-CD5 ricin immunotoxins. | 1989 | J. Immunol. Methods | pmid:2474026 |
Arock M et al. | Histamine-releasing activity of endogenous peptides on mast cells derived from different sites and species. | 1989 | Int. Arch. Allergy Appl. Immunol. | pmid:2474510 |
Mossman SP et al. | The effects of 5-azacytidine, 12-O-tetradecanoylphorbol 13-acetate and sodium n-butyrate on reactivation of alphaherpesvirus saimiri from explant cultures of latently infected rabbit dorsal root ganglia. | 1989 | J. Gen. Virol. | pmid:2476529 |
Foss FM et al. | Alterations in the expression of pp60c-src and p56lck associated with butyrate-induced differentiation of human colon carcinoma cells. | 1989 | Oncogene Res. | pmid:2476706 |
Brantschen S et al. | Factors influencing proliferation and histamine content of cultured human bone marrow cells. | 1989 | Immunobiology | pmid:2477328 |
Constantoulakis P et al. | On the induction of fetal hemoglobin by butyrates: in vivo and in vitro studies with sodium butyrate and comparison of combination treatments with 5-AzaC and AraC. | 1989 | Blood | pmid:2478217 |
Ramsdell JS and Tashjian AH | GH4 pituitary cell variants selected as nonresponsive to thyrotropin-releasing hormone-enhanced substratum adhesion are nonresponsive to epidermal growth factor: evidence for a common signaling defect. | 1989 | J. Cell. Physiol. | pmid:2480354 |
Alberts P | Effects of N6,2'-O-dibutyryladenosine 3',5'-cyclic monophosphate, adenosine, and of oxotremorine and 3-isobutyl-1-methylxanthine on the electrically evoked [3H]acetylcholine secretion in the guinea-pig ileum myenteric plexus. | 1989 | Acta Physiol. Scand. | pmid:2481381 |
Kubin T et al. | Inhibition of DNA synthesis of adult rat hepatocytes in primary culture by dibutyrylcytidine 3', 5'-cyclic monophosphate. | 1989 | Cell Biol. Int. Rep. | pmid:2481569 |
Clarke J et al. | A comparison of the effects of various stimulatory agents on t-PA secretion by normal and malignant cell lines. | 1989 | Cell Biochem. Funct. | pmid:2481573 |
Constantoulakis P et al. | Butyrate stimulates HbF in adult baboons. | 1989 | Prog. Clin. Biol. Res. | pmid:2482502 |
Schulz M et al. | Regulation by dibutyryl cyclic AMP of carnosine synthesis in astroglia-rich primary cultures kept in serum-free medium. | 1989 | J. Neurochem. | pmid:2462017 |
Nackerdien Z et al. | Chromatin decondensed by acetylation shows an elevated radiation response. | 1989 | Radiat. Res. | pmid:2922469 |
Casper D and Davies P | Stimulation of choline acetyltransferase activity by retinoic acid and sodium butyrate in a cultured human neuroblastoma. | 1989 | Brain Res. | pmid:2924123 |
Casper D and Davies P | Mechanism of activation of choline acetyltransferase in a human neuroblastoma cell line. | 1989 | Brain Res. | pmid:2924124 |
Binder HJ and Mehta P | Short-chain fatty acids stimulate active sodium and chloride absorption in vitro in the rat distal colon. | 1989 | Gastroenterology | pmid:2925072 |
Hock RA et al. | Expression of human adenosine deaminase from various strong promoters after gene transfer into human hematopoietic cell lines. | 1989 | Blood | pmid:2752148 |
Champelovier P et al. | Establishment and characterization of a granulocytic subclone (UM 384) from the monoblastic cell line U 937. | 1989 | Exp. Hematol. | pmid:2753087 |
Ortiz-Caro J et al. | Organization of the thyroid hormone receptor in the chromatin of C6 glial cells: evidence that changes in receptor levels are not associated with changes in receptor distribution. | 1989 | FEBS Lett. | pmid:2753141 |
Firmansyah A et al. | Isolated colonocyte metabolism of glucose, glutamine, n-butyrate, and beta-hydroxybutyrate in malnutrition. | 1989 | Gastroenterology | pmid:2753323 |
Favinger J et al. | Rhodospirillum centenum, sp. nov., a thermotolerant cyst-forming anoxygenic photosynthetic bacterium. | 1989 | Antonie Van Leeuwenhoek | pmid:2757370 |
Marchant P et al. | A selective inhibitor of N8-acetylspermidine deacetylation in mice and HeLa cells without effects on histone deacetylation. | 1989 | Arch. Biochem. Biophys. | pmid:2757387 |
Herz F | Effect of human serum on alkaline phosphatase induction in cultured human tumor cells. | 1989 | Experientia | pmid:2759209 |
Beattie DT et al. | Baclofen antagonism by 4-amino-3-(5-methoxybenzo[b]furan-2-yl) butanoic acid in the cat spinal cord. | 1989 | Neurosci. Lett. | pmid:2761779 |
Chiao CS and Price JC | Modification of gelatin beadlets for zero-order sustained release. | 1989 | Pharm. Res. | pmid:2762229 |
Xu K et al. | [Studies on cell surface fibronectin of transformed Syrian hamster lung cells induced by butyric acid]. | 1989 | Shi Yan Sheng Wu Xue Bao | pmid:2763766 |
Ramanathan B and Smerdon MJ | Enhanced DNA repair synthesis in hyperacetylated nucleosomes. | 1989 | J. Biol. Chem. | pmid:2738057 |
Ramakrishna BS et al. | Estimation of phenolic conjugation by colonic mucosa. | 1989 | J. Clin. Pathol. | pmid:2738167 |
Higgins PJ and Ryan MP | Cytoarchitecture of ras oncogene-expressing tumor cells: butyrate modulation of substrate adhesion, cytoskeletal actin content and subcellular microfilament distribution. | 1989 | Int. J. Biochem. | pmid:2684700 |
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Sussman NL et al. | Intestinal alkaline phosphatase is secreted bidirectionally from villous enterocytes. | 1989 | Am. J. Physiol. | pmid:2546440 |
Ryan MP and Higgins PJ | Sodium-n-butyrate induces secretion and substrate accumulation of p52 in Kirsten sarcoma virus-transformed rat kidney fibroblasts. | 1989 | Int. J. Biochem. | pmid:2546834 |
Yanase S and Sugawara K | Inhibition of chemical Epstein-Barr virus induction by dimethyl sulfoxide and related polar compounds. | 1989 | Intervirology | pmid:2546900 |
Balzarini J et al. | Synthesis and antiviral activity of the enantiomeric forms of carba-5-iodo-2'-deoxyuridine and carba-(E)-5-(2-bromovinyl)-2'-deoxyuridine. | 1989 | J. Med. Chem. | pmid:2547072 |
Kemp LM and Latchman DS | Regulated transcription of herpes simplex virus immediate-early genes in neuroblastoma cells. | 1989 | Virology | pmid:2548331 |
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Nakada MT et al. | Genetic regulation of beta 2-adrenergic receptors in 3T3-L1 fibroblasts. | 1989 | Biochem. J. | pmid:2549959 |
Kurakata S et al. | Lysis of P3HR-1 cells induced to enter the viral cycle by antibody-dependent and independent immunological mechanisms. | 1989 | Cell. Immunol. | pmid:2550147 |
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James DE et al. | Isoproterenol stimulates phosphorylation of the insulin-regulatable glucose transporter in rat adipocytes. | 1989 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2554313 |
Lotan R et al. | Modulation of galactoside-binding lectins in tumor cells by differentiation-inducing agents. | 1989 | Cancer Lett. | pmid:2555043 |
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Sorimachi K et al. | Inhibitory effect of dibutyryl cyclic adenosine monophosphate on the induction of alkaline phosphatase in human fetal liver cell line. | 1989 | Biochim. Biophys. Acta | pmid:2535785 |
Benjamin LA et al. | Alterations in plasminogen activator and inhibitor activity during the differentiation of a human neuroblastoma cell line, SMS-KAN. | 1989 | Cancer Lett. | pmid:2537681 |
Campbell MA et al. | Y-79 retinoblastoma cells: isolation and characterization of clonal lineages. | 1989 | Exp. Eye Res. | pmid:2537744 |
Abemayor E and Sidell N | Human neuroblastoma cell lines as models for the in vitro study of neoplastic and neuronal cell differentiation. | 1989 | Environ. Health Perspect. | pmid:2538324 |
Bartholomeusz RK et al. | Pancreatic islet A2B5- and 3G5-reactive gangliosides are markers of differentiation in rat insulinoma cells. | 1989 | Endocrinology | pmid:2541995 |
Bertoni G et al. | Intracellular synthesis of Epstein-Barr virus membrane antigen gp350/220. Inhibitory effect of monensin on its expression. | 1989 | Intervirology | pmid:2542183 |
Bensaadi N et al. | Modulation of enzymatic activities during spontaneous and induced differentiation in a human pancreatic adenocarcinoma cell line CAPAN-1. | 1989 | Int. J. Pancreatol. | pmid:2543714 |
Daniel P et al. | Pharmacokinetic study of butyric acid administered in vivo as sodium and arginine butyrate salts. | 1989 | Clin. Chim. Acta | pmid:2667816 |
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