butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yoneda S et al. | Effects of short-chain fatty acids on Actinomyces naeslundii biofilm formation. | 2013 | Mol Oral Microbiol | pmid:23731652 |
Wiese BI et al. | Short communication: Interrelationship between butyrate and glucose supply on butyrate and glucose oxidation by ruminal epithelial preparations. | 2013 | J. Dairy Sci. | pmid:23810600 |
Antharam VC et al. | Intestinal dysbiosis and depletion of butyrogenic bacteria in Clostridium difficile infection and nosocomial diarrhea. | 2013 | J. Clin. Microbiol. | pmid:23804381 |
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Gałecka M et al. | Faecalibacterium prausnitzii and Crohn's disease - is there any connection? | 2013 | Pol. J. Microbiol. | pmid:23829084 |
Valvassori SS et al. | Sodium butyrate reverses the inhibition of Krebs cycle enzymes induced by amphetamine in the rat brain. | 2013 | J Neural Transm | pmid:23851624 |
St Laurent R et al. | Sodium butyrate improves locomotor impairment and early mortality in a rotenone-induced Drosophila model of Parkinson's disease. | 2013 | Neuroscience | pmid:23623990 |
Kidwai F et al. | The effects of CD44 down-regulation on stem cell properties of head and neck cancer cell lines. | 2013 | J. Oral Pathol. Med. | pmid:23627635 |
Nör C et al. | The histone deacetylase inhibitor sodium butyrate promotes cell death and differentiation and reduces neurosphere formation in human medulloblastoma cells. | 2013 | Mol. Neurobiol. | pmid:23516101 |
Chen HC et al. | Preparation of highly conjugated water-dispersible graphene-butyric acid for the enhancement of electron transfer within polyamic acid-benzoxazole: potential applications in electrochemical sensing. | 2013 | Biosens Bioelectron | pmid:23517822 |
Yaku K et al. | AMPK synergizes with the combined treatment of 1'-acetoxychavicol acetate and sodium butyrate to upregulate phase II detoxifying enzyme activities. | 2013 | Mol Nutr Food Res | pmid:23559539 |
Itzhak Y et al. | Sodium butyrate-induced histone acetylation strengthens the expression of cocaine-associated contextual memory. | 2013 | Neurobiol Learn Mem | pmid:23567105 |
Paskova L et al. | Different effect of sodium butyrate on cancer and normal prostate cells. | 2013 | Toxicol In Vitro | pmid:23524101 |
Wang P et al. | Trichostatin A protects against cisplatin-induced ototoxicity by regulating expression of genes related to apoptosis and synaptic function. | 2013 | Neurotoxicology | pmid:23558232 |
de Conti A et al. | The chemopreventive activity of the butyric acid prodrug tributyrin in experimental rat hepatocarcinogenesis is associated with p53 acetylation and activation of the p53 apoptotic signaling pathway. | 2013 | Carcinogenesis | pmid:23568954 |
Zhang L et al. | Genome-wide screening for genes associated with valproic acid sensitivity in fission yeast. | 2013 | PLoS ONE | pmid:23861937 |
Muhammad SI et al. | Upregulation of genes related to bone formation by γ-amino butyric acid and γ-oryzanol in germinated brown rice is via the activation of GABAB-receptors and reduction of serum IL-6 in rats. | 2013 | Clin Interv Aging | pmid:24098073 |
Maioli M et al. | Amniotic fluid stem cells morph into a cardiovascular lineage: analysis of a chemically induced cardiac and vascular commitment. | 2013 | Drug Des Devel Ther | pmid:24101862 |
Mu D et al. | Sodium butyrate induces growth inhibition and apoptosis in human prostate cancer DU145 cells by up-regulation of the expression of annexin A1. | 2013 | PLoS ONE | pmid:24086397 |
Li H et al. | Development of phenotypic screening assays for γ-globin induction using primary human bone marrow day 7 erythroid progenitor cells. | 2013 | J Biomol Screen | pmid:24163393 |
Cheng J et al. | Synthesis and properties of macrocyclic butanoic acid conjugates as a promising delivery formulation for the nutrition of colon. | 2013 | ScientificWorldJournal | pmid:24163636 |
Misaghi S et al. | Resilient immortals, characterizing and utilizing Bax/Bak deficient Chinese hamster ovary (CHO) cells for high titer antibody production. | 2013 May-Jun | Biotechnol. Prog. | pmid:23596153 |
Tigunova EA et al. | [Alternative type of fuel--biobutanol]. | 2013 Nov-Dec | Tsitol. Genet. | pmid:24437198 |
Wu Z et al. | Histone deacetylase inhibitors suppress the growth of human osteosarcomas in vitro and in vivo. | 2013 Oct-Dec | J BUON | pmid:24344034 |
Molina S et al. | Antiproliferative effect of alkylglycerols as vehicles of butyric acid on colon cancer cells. | 2013 Oct-Nov | Chem. Phys. Lipids | pmid:23973778 |
Unno T et al. | Effect of dietary supplementation of (-)-epigallocatechin gallate on gut microbiota and biomarkers of colonic fermentation in rats. | 2014 | J. Nutr. Sci. Vitaminol. | pmid:25078378 |
Vidrine K et al. | Resistant starch from high amylose maize (HAM-RS2) and dietary butyrate reduce abdominal fat by a different apparent mechanism. | 2014 | Obesity (Silver Spring) | pmid:23630079 |
Ozadali K et al. | Synthesis and antimycobacterial activities of some new thiazolylhydrazone derivatives. | 2014 | Bioorg. Med. Chem. Lett. | pmid:24631185 |
Shen H et al. | BMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progression. | 2014 | J. Cell. Mol. Med. | pmid:24571310 |
Karki P et al. | Yin Yang 1 is a repressor of glutamate transporter EAAT2, and it mediates manganese-induced decrease of EAAT2 expression in astrocytes. | 2014 | Mol. Cell. Biol. | pmid:24469401 |
Pérez-Carro R et al. | Functional analysis and in vitro correction of splicing FAH mutations causing tyrosinemia type I. | 2014 | Clin. Genet. | pmid:23895425 |
Lopez CA et al. | Collateral damage: microbiota-derived metabolites and immune function in the antibiotic era. | 2014 | Cell Host Microbe | pmid:25121745 |
Cho HJ and Song MJ | A gammaherpesvirus establishes persistent infection in neuroblastoma cells. | 2014 | Mol. Cells | pmid:25092213 |
Li S et al. | High-grain diets suppress ruminal tissue abundance of angiopoietin-like protein 4 in cattle. | 2014 | J. Anim. Sci. | pmid:25085388 |
Shin J et al. | The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner. | 2014 | J. Biol. Chem. | pmid:25037223 |
Pasvolsky R et al. | Butyric acid released during milk lipolysis triggers biofilm formation of Bacillus species. | 2014 | Int. J. Food Microbiol. | pmid:24801271 |
Maggio A et al. | Daily sodium butyrate enema for the prevention of radiation proctitis in prostate cancer patients undergoing radical radiation therapy: results of a multicenter randomized placebo-controlled dose-finding phase 2 study. | 2014 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:24803033 |
Ellis JT et al. | Microbial bioproducts from cheese whey through fermentation with wastewater sludge Clostridium isolates. | 2014 | Can. J. Microbiol. | pmid:24898684 |
Ochiai K and Kurita-Ochiai T | [Alternative effects of a metabolic by-product, butyric acid, produced by oral anaerobes]. | 2014 | Nippon Yakurigaku Zasshi | pmid:25109521 |
Liu W et al. | Effects of dietary microencapsulated sodium butyrate on growth, intestinal mucosal morphology, immune response and adhesive bacteria in juvenile common carp (Cyprinus carpio) pre-fed with or without oxidised oil. | 2014 | Br. J. Nutr. | pmid:24774835 |
Ladirat SE et al. | Exploring the effects of galacto-oligosaccharides on the gut microbiota of healthy adults receiving amoxicillin treatment. | 2014 | Br. J. Nutr. | pmid:24925303 |
Blank M et al. | Basolateral amygdala activity is required for enhancement of memory consolidation produced by histone deacetylase inhibition in the hippocampus. | 2014 | Neurobiol Learn Mem | pmid:24583371 |
Possebom G et al. | Esterification of fatty acids by Penicillium crustosum lipase in a membrane reactor. | 2014 | J. Sci. Food Agric. | pmid:24578290 |
Zhang Z et al. | Sodium butyrate facilitates reprogramming by derepressing OCT4 transactivity at the promoter of embryonic stem cell-specific miR-302/367 cluster. | 2014 | Cell Reprogram | pmid:24568633 |
Bolhari B et al. | Acid and microhardness of mineral trioxide aggregate and mineral trioxide aggregate-like materials. | 2014 | J Endod | pmid:24565666 |
Ai B et al. | Butyric acid fermentation of sodium hydroxide pretreated rice straw with undefined mixed culture. | 2014 | J. Microbiol. Biotechnol. | pmid:24561721 |
Khan S and Jena GB | Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: study in juvenile diabetic rat. | 2014 | Chem. Biol. Interact. | pmid:24530320 |
Ferreira AC et al. | Histone deacetylase inhibitor prevents cell growth in Burkitt's lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101. | 2014 | Ann. Hematol. | pmid:24577510 |