butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Waterborg JH | Steady-state levels of histone acetylation in Saccharomyces cerevisiae. | 2000 | J. Biol. Chem. | pmid:10777603 |
Chung YL et al. | A novel approach for nasopharyngeal carcinoma treatment uses phenylbutyrate as a protein kinase C modulator: implications for radiosensitization and EBV-targeted therapy. | 2000 | Clin. Cancer Res. | pmid:10778977 |
Douillard JY et al. | Phase I trial of interleukin-2 and high-dose arginine butyrate in metastatic colorectal cancer. | 2000 | Cancer Immunol. Immunother. | pmid:10782866 |
Menssen HD et al. | Wilms' tumor gene (WT1) expression in lung cancer, colon cancer and glioblastoma cell lines compared to freshly isolated tumor specimens. | 2000 | J. Cancer Res. Clin. Oncol. | pmid:10782896 |
Ding ST et al. | Modulation of porcine adipocyte beta-adrenergic receptors by hormones and butyrate. | 2000 | J. Anim. Sci. | pmid:10784182 |
McCollum MQ et al. | Absorption of 2-hydroxy-4-(methylthio)butanoic acid by isolated sheep ruminal and omasal epithelia. | 2000 | J. Anim. Sci. | pmid:10784201 |
Xie P et al. | Induction of TrkA expression by differentiation inducers in human myeloid leukemia KG-1 cells. | 2000 | Leuk. Lymphoma | pmid:10784405 |
Georgalaki MD et al. | Biochemical properties of Streptococcus macedonicus strains isolated from Greek Kasseri cheese. | 2000 | J. Appl. Microbiol. | pmid:10792542 |
Vernia P et al. | Combined oral sodium butyrate and mesalazine treatment compared to oral mesalazine alone in ulcerative colitis: randomized, double-blind, placebo-controlled pilot study. | 2000 | Dig. Dis. Sci. | pmid:10795763 |
Sandborn W et al. | Pharmacotherapy for inducing and maintaining remission in pouchitis. | 2000 | Cochrane Database Syst Rev | pmid:10796613 |
Mariadason JM et al. | Divergent phenotypic patterns and commitment to apoptosis of Caco-2 cells during spontaneous and butyrate-induced differentiation. | 2000 | J. Cell. Physiol. | pmid:10797309 |
Haza AI et al. | Effect of colonic luminal components on induction of apoptosis in human colonic cell lines. | 2000 | Nutr Cancer | pmid:10798220 |
Kobayashi T et al. | Purification from conditioned medium and chemical identification of a factor that inhibits somatic embryogenesis in carrot. | 2000 | Plant Cell Physiol. | pmid:10805589 |
Litvak DA et al. | Induction of apoptosis in human gastric cancer by sodium butyrate. | 2000 Mar-Apr | Anticancer Res. | pmid:10810354 |
McMasters RA et al. | Two-drug combinations that increase apoptosis and modulate bak and bcl-X(L) expression in human colon tumor cell lines transduced with herpes simplex virus thymidine kinase. | 2000 | Cancer Gene Ther. | pmid:10811474 |
Heda GD and Marino CR | Surface expression of the cystic fibrosis transmembrane conductance regulator mutant DeltaF508 is markedly upregulated by combination treatment with sodium butyrate and low temperature. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10814518 |
Müller JA and Schink B | Initial steps in the fermentation of 3-hydroxybenzoate by Sporotomaculum hydroxybenzoicum. | 2000 | Arch. Microbiol. | pmid:10816048 |
Vilaboa NE et al. | Regulation of multidrug resistance 1 (MDR1)/P-glycoprotein gene expression and activity by heat-shock transcription factor 1 (HSF1). | 2000 | J. Biol. Chem. | pmid:10816597 |
Ranganna K et al. | Butyrate inhibits proliferation-induced proliferating cell nuclear antigen expression (PCNA) in rat vascular smooth muscle cells. | 2000 | Mol. Cell. Biochem. | pmid:10821433 |
Broda DM et al. | Clostridium gasigenes sp. nov., a psychrophile causing spoilage of vacuum-packed meat. | 2000 | Int. J. Syst. Evol. Microbiol. | pmid:10826793 |
Gabbianelli M et al. | Hemoglobin switching in unicellular erythroid culture of sibling erythroid burst-forming units: kit ligand induces a dose-dependent fetal hemoglobin reactivation potentiated by sodium butyrate. | 2000 | Blood | pmid:10828043 |
Diaz PI et al. | The response to oxidative stress of Fusobacterium nucleatum grown in continuous culture. | 2000 | FEMS Microbiol. Lett. | pmid:10828396 |
Lacoste V et al. | Virological and molecular characterisation of a new B lymphoid cell line, established from an AIDS patient with primary effusion lymphoma, harbouring both KSHV/HHV8 and EBV viruses. | 2000 | Leuk. Lymphoma | pmid:10830748 |
Wächtershäuser A et al. | PPAR-gamma is selectively upregulated in Caco-2 cells by butyrate. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10833422 |
Vider BZ et al. | Deregulated expression of homeobox-containing genes, HOXB6, B8, C8, C9, and Cdx-1, in human colon cancer cell lines. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10833444 |
Tukey RH and Strassburg CP | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. | 2000 | Annu. Rev. Pharmacol. Toxicol. | pmid:10836148 |
Yoon JH et al. | Augmentation of urea-synthetic capacity by inhibition of nitric oxide synthesis in butyrate-induced differentiated human hepatocytes. | 2000 | FEBS Lett. | pmid:10838080 |
Roediger WE and Babidge WJ | Nitric oxide effect on colonocyte metabolism: co-action of sulfides and peroxide. | 2000 | Mol. Cell. Biochem. | pmid:10839206 |
Liu Y et al. | Human papillomavirus type 16 E6 and HPV-16 E6/E7 sensitize human keratinocytes to apoptosis induced by chemotherapeutic agents: roles of p53 and caspase activation. | 2000 | J. Cell. Biochem. | pmid:10842327 |
Defnoun S et al. | Papillibacter cinnamivorans gen. nov., sp. nov., a cinnamate-transforming bacterium from a shea cake digester. | 2000 | Int. J. Syst. Evol. Microbiol. | pmid:10843066 |
Ishiwata H et al. | Short-chain fatty acids inhibit the release and content of growth hormone in anterior pituitary cells of the goat. | 2000 | Gen. Comp. Endocrinol. | pmid:10843791 |
Hughes AK et al. | Cytotoxic effect of Shiga toxin-1 on human glomerular epithelial cells. | 2000 | Kidney Int. | pmid:10844605 |
Allemann M et al. | Effect of sodium butyric acid, sodium valerianic acid, and osmolarity on contractility of specimens of intestinal wall obtained from the cecum and spiral colon of healthy cows. | 2000 | Am. J. Vet. Res. | pmid:10850845 |
Andoh A et al. | Modulation of complement component (C3 and factor B) biosynthesis by a histone deacetylase inhibitor in human intestinal epithelial cells. | 2000 | Int. J. Mol. Med. | pmid:10851266 |
Liu SJ and Steinbüchel A | Exploitation of butyrate kinase and phosphotransbutyrylase from Clostridium acetobutylicum for the in vitro biosynthesis of poly(hydroxyalkanoic acid). | 2000 | Appl. Microbiol. Biotechnol. | pmid:10855714 |
Segouffin-Cariou C et al. | Characterization of the epstein-barr virus BRRF1 gene, located between early genes BZLF1 and BRLF1. | 2000 | J. Gen. Virol. | pmid:10859385 |
Bonge H et al. | Cytostar-T scintillating microplate assay for measurement of sodium-dependent bile acid uptake in transfected HEK-293 cells. | 2000 | Anal. Biochem. | pmid:10860504 |
Wilson AJ and Gibson PR | Role of urokinase and its receptor in basal and stimulated colonic epithelial cell migration in vitro. | 2000 | Gut | pmid:10861271 |
McMillan L et al. | Bile acids reduce the apoptosis-inducing effects of sodium butyrate on human colon adenoma (AA/C1) cells: implications for colon carcinogenesis. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10873561 |
Takahashi M et al. | Studies of the effect of Clostridium butyricum on Helicobacter pylori in several test models including gnotobiotic mice. | 2000 | J. Med. Microbiol. | pmid:10882089 |
Olano-Martin E et al. | In vitro fermentability of dextran, oligodextran and maltodextrin by human gut bacteria. | 2000 | Br. J. Nutr. | pmid:10884713 |
Belobrajdic DP and McIntosh GH | Dietary butyrate inhibits NMU-induced mammary cancer in rats. | 2000 | Nutr Cancer | pmid:10890033 |
Ferguson LR et al. | Comparative effects of three resistant starch preparations on transit time and short-chain fatty acid production in rats. | 2000 | Nutr Cancer | pmid:10890035 |
Wu YD and Song JD | The expression of glucose regulated protein-94 in colorectal carcinoma cells treated by sodium butyrate. | 2000 | Cell Res. | pmid:10896173 |
Karlsson A et al. | CO2-dependent fermentation of phenol to acetate, butyrate and benzoate by an anaerobic, pasteurised culture. | 2000 May-Jun | Arch. Microbiol. | pmid:10896220 |
Bai L and Merchant JL | Transcription factor ZBP-89 cooperates with histone acetyltransferase p300 during butyrate activation of p21waf1 transcription in human cells. | 2000 | J. Biol. Chem. | pmid:10899165 |
Lupton JR | Is fiber protective against colon cancer? Where the research is leading us. | 2000 Jul-Aug | Nutrition | pmid:10906555 |
Lane MA et al. | Sheep rumen metabolic development in response to age and dietary treatments. | 2000 | J. Anim. Sci. | pmid:10907843 |
Peinnequin A et al. | Non-thermal effects of continuous 2.45 GHz microwaves on Fas-induced apoptosis in human Jurkat T-cell line. | 2000 | Bioelectrochemistry | pmid:10910164 |
Krig SR and Rice RH | TCDD suppression of tissue transglutaminase stimulation by retinoids in malignant human keratinocytes. | 2000 | Toxicol. Sci. | pmid:10910994 |
Witt O et al. | Tributyrin plus all-trans-retinoic acid efficiently induces fetal hemoglobin expression in human erythroleukemia cells. | 2000 | Am. J. Hematol. | pmid:10911389 |
Jørgensen J and Mortensen PB | Utilization of short-chain fatty acids by colonic mucosal tissue strips. A new method of assessing colonic mucosal metabolism. | 2000 | Scand. J. Gastroenterol. | pmid:10912669 |
Lee CH et al. | NMR studies on novel antitumor drug candidates, deoxoartemisinin and carboxypropyldeoxoartemisinin. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10913344 |
Rose LJ et al. | Volatile organic compounds associated with microbial growth in automobile air conditioning systems. | 2000 | Curr. Microbiol. | pmid:10915209 |
Haas MJ et al. | Effects of ketoacidosis on rat apolipoprotein A1 gene expression: a link with acidosis but not with ketones. | 2000 | J. Mol. Endocrinol. | pmid:10915225 |
Rosella O et al. | Polyunsaturated fatty acids reduce non-receptor-mediated transcellular permeation of protein across a model of intestinal epithelium in vitro. | 2000 | J. Gastroenterol. Hepatol. | pmid:10921416 |
Diamond SE and Gutierrez-Hartmann A | The Pit-1beta domain dictates active repression and alteration of histone acetylation of the proximal prolactin promoter. | 2000 | J. Biol. Chem. | pmid:10921928 |
Lawson PA et al. | New LL-diaminopimelic acid-containing actinomycetes from hypersaline, heliothermal and meromictic Antarctic Ekho Lake: Nocardioides aquaticus sp. nov. and Friedmanniella [correction of Friedmannielly] lacustris sp. nov. | 2000 | Syst. Appl. Microbiol. | pmid:10930074 |
Müller F et al. | Role of Na+/H+ exchange and HCO3- transport in pHi recovery from intracellular acid load in cultured epithelial cells of sheep rumen. | 2000 | J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. | pmid:10935525 |
Huang KX et al. | Identification and characterization of a second butyrate kinase from Clostridium acetobutylicum ATCC 824. | 2000 | J. Mol. Microbiol. Biotechnol. | pmid:10937485 |
Parrer G et al. | Conversion of solvent evaporation residues from the AB- (acetone - butanol) bioprocess into bacterial cells accumulating thermoplastic polyesters. | 2000 | J. Mol. Microbiol. Biotechnol. | pmid:10937491 |
Magee RM et al. | Synthesis of osteonectin by human retinal pigment epithelial cells is modulated by cell density. | 2000 | Invest. Ophthalmol. Vis. Sci. | pmid:10937587 |
Parrer G et al. | Conversion of solvent evaporation residues from the AB- (acetone-butanol) bioprocess into bacterial cells accumulating thermoplastic polyesters. | 2000 | J. Mol. Microbiol. Biotechnol. | pmid:10939239 |
Zelivianski S et al. | Expression of receptor protein tyrosine phosphatase alpha mRNA in human prostate cancer cell lines. | 2000 | Mol. Cell. Biochem. | pmid:10939623 |
Matthies C et al. | Anaerovorax odorimutans gen. nov., sp. nov., a putrescine-fermenting, strictly anaerobic bacterium. | 2000 | Int. J. Syst. Evol. Microbiol. | pmid:10939665 |
Segain JP et al. | Butyrate inhibits inflammatory responses through NFkappaB inhibition: implications for Crohn's disease. | 2000 | Gut | pmid:10940278 |
Sanderson IR and Naik S | Dietary regulation of intestinal gene expression. | 2000 | Annu. Rev. Nutr. | pmid:10940337 |
Andersen DC et al. | Multiple cell culture factors can affect the glycosylation of Asn-184 in CHO-produced tissue-type plasminogen activator. | 2000 | Biotechnol. Bioeng. | pmid:10940860 |
Koyama Y et al. | Histone deacetylase inhibitors suppress IL-2-mediated gene expression prior to induction of apoptosis. | 2000 | Blood | pmid:10942396 |
Marilley D and Schwaller B | Association between the calcium-binding protein calretinin and cytoskeletal components in the human colon adenocarcinoma cell line WiDr. | 2000 | Exp. Cell Res. | pmid:10942575 |
Gilbert KM et al. | Potential clinical use of butyric acid derivatives to induce antigen-specific T cell inactivation. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10945871 |
Mboera LE et al. | The response of Culex quinquefasciatus (Diptera: culicidae) to traps baited with carbon dioxide, 1-octen-3-ol, acetone, butyric acid and human foot odour in Tanzania. | 2000 | Bull. Entomol. Res. | pmid:10948375 |
Jensen UB et al. | Transgene expression in human epidermal keratinocytes: cell cycle arrest of productively transfected cells. | 2000 | Exp. Dermatol. | pmid:10949553 |
Shadan FF and Villarreal LP | n-Butyrate mediated inhibition of papovavirus DNA replication in vivo and in cell culture: a mechanistic approach. | 2000 | Virus Genes | pmid:10949947 |
Masuda T et al. | Up-regulation of E-cadherin and I-catenin in human hepatocellular carcinoma cell lines by sodium butyrate and interferon-alpha. | 2000 | In Vitro Cell. Dev. Biol. Anim. | pmid:10949998 |
Oufir LE et al. | Relationships between transit time in man and in vitro fermentation of dietary fiber by fecal bacteria. | 2000 | Eur J Clin Nutr | pmid:10951507 |
Rooman I et al. | Modulation of rat pancreatic acinoductal transdifferentiation and expression of PDX-1 in vitro. | 2000 | Diabetologia | pmid:10952464 |
Tsai LC et al. | Apoptosis induced by the sodium butyrate in human gastric cancer TMK-1 cells. | 2000 Jul-Aug | Anticancer Res. | pmid:10953308 |
Gostner A et al. | Comparisons of the anti-proliferative effects of butyrate and aspirin on human colonic mucosa in vitro. | 2000 | Eur. J. Cancer Prev. | pmid:10954260 |
Nudelman A and Rephaeli A | Novel mutual prodrug of retinoic and butyric acids with enhanced anticancer activity. | 2000 | J. Med. Chem. | pmid:10956204 |
Coradini D et al. | Sodium butyrate modulates cell cycle-related proteins in HT29 human colonic adenocarcinoma cells. | 2000 | Cell Prolif. | pmid:10959623 |
Garjani A et al. | Effects of extracts from flowering tops of Crataegus meyeri A. Pojark. on ischaemic arrhythmias in anaesthetized rats. | 2000 | Phytother Res | pmid:10960896 |
Wisker E et al. | Short-chain fatty acids produced in vitro from fibre residues obtained from mixed diets containing different breads and in human faeces during the ingestion of the diets. | 2000 | Br. J. Nutr. | pmid:10961158 |
Wolever TM and Chiasson JL | Acarbose raises serum butyrate in human subjects with impaired glucose tolerance. | 2000 | Br. J. Nutr. | pmid:10961161 |
Birkett AM et al. | Changes to the quantity and processing of starchy foods in a western diet can increase polysaccharides escaping digestion and improve in vitro fermentation variables. | 2000 | Br. J. Nutr. | pmid:10961162 |
Hsu CP et al. | Suppression of proline-directed protein kinase F(A) expression potentiates erythroid differentiation of human myeloid leukemia cells. | 2000 | Cancer | pmid:10964330 |
Salah AM et al. | In vitro purgative effect of Ruellia praetermissa. Sceinf.ex.Lindau (Acanthaceae). | 2000 | J Ethnopharmacol | pmid:10967480 |
Mariadason JM et al. | Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer. | 2000 | Cancer Res. | pmid:10969808 |
Pedersen G et al. | A simple method to establish short-term cultures of normal human colonic epithelial cells from endoscopic biopsy specimens. Comparison of isolation methods, assessment of viability and metabolic activity. | 2000 | Scand. J. Gastroenterol. | pmid:10972184 |
KovarÃková M et al. | TNF-alpha modulates the differentiation induced by butyrate in the HT-29 human colon adenocarcinoma cell line. | 2000 | Eur. J. Cancer | pmid:10974633 |
Pedersen G et al. | Cytokine-induced impairment of short-chain fatty acid oxidation and viability in human colonic epithelial cells. | 2000 | Cytokine | pmid:10976002 |
Weinmann W et al. | Simultaneous determination of THC-COOH and THC-COOH-glucuronide in urine samples by LC/MS/MS. | 2000 | Forensic Sci. Int. | pmid:10978652 |
Xie P et al. | Nerve growth factor potentiated the sodium butyrate- and PMA-induced megakaryocytic differentiation of K562 leukemia cells. | 2000 | Leuk. Res. | pmid:10978779 |
Kano K et al. | Complexation of polyvalent cyclodextrin ions with oppositely charged guests: entropically favorable complexation due to dehydration. | 2000 | Chemistry | pmid:10985719 |
Karlsson S et al. | Toxins, butyric acid, and other short-chain fatty acids are coordinately expressed and down-regulated by cysteine in Clostridium difficile. | 2000 | Infect. Immun. | pmid:10992498 |
Maier S et al. | Tributyrin induces differentiation, growth arrest and apoptosis in androgen-sensitive and androgen-resistant human prostate cancer cell lines. | 2000 | Int. J. Cancer | pmid:11004676 |
Shie JL et al. | Role of gut-enriched Krüppel-like factor in colonic cell growth and differentiation. | 2000 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11005769 |
Lauricella M et al. | Synergistic cytotoxic interactions between sodium butyrate, MG132 and camptothecin in human retinoblastoma Y79 cells. | 2000 Nov-Dec | Tumour Biol. | pmid:11006574 |
Le Blay G et al. | Short-chain fatty acids induce cytoskeletal and extracellular protein modifications associated with modulation of proliferation on primary culture of rat intestinal smooth muscle cells. | 2000 | Dig. Dis. Sci. | pmid:11007115 |
Evdokiou A et al. | Identification of a novel calcitonin-response element in the promoter of the human p21WAF1/CIP1 gene. | 2000 | J. Mol. Endocrinol. | pmid:11013346 |