butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Acidosis D000138 13 associated lipids
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Alzheimer Disease D000544 76 associated lipids
Anaplasia D000708 1 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Angina Pectoris D000787 27 associated lipids
Aphakia, Postcataract D001036 1 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Astigmatism D001251 1 associated lipids
Ataxia Telangiectasia D001260 6 associated lipids
Sarcoma, Avian D001357 2 associated lipids
Body Weight D001835 333 associated lipids
Brain Diseases D001927 27 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Burns D002056 34 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Cattle Diseases D002418 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Colitis D003092 69 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Colorectal Neoplasms, Hereditary Nonpolyposis D003123 2 associated lipids
Constipation D003248 8 associated lipids
Corneal Diseases D003316 13 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Dental Leakage D003763 5 associated lipids
Dentin, Secondary D003809 2 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Diarrhea D003967 32 associated lipids
Disease Models, Animal D004195 4 associated lipids
Diverticulitis D004238 1 associated lipids
Diverticulitis, Colonic D004239 1 associated lipids
Dysentery D004403 4 associated lipids
Edema D004487 152 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Facial Injuries D005151 1 associated lipids
Fatty Liver D005234 48 associated lipids
Fragile X Syndrome D005600 5 associated lipids
Glioma D005910 112 associated lipids
Glycogen Storage Disease Type II D006009 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Hemolysis D006461 131 associated lipids
Hemorrhoids D006484 2 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Herpesviridae Infections D006566 4 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Hyperkinesis D006948 11 associated lipids
Hypothyroidism D007037 32 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Insulinoma D007340 28 associated lipids
Intestinal Neoplasms D007414 2 associated lipids
Ketosis D007662 13 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Laryngeal Neoplasms D007822 7 associated lipids
Leukemia D007938 74 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Leukemia, Megakaryoblastic, Acute D007947 7 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lymphatic Metastasis D008207 10 associated lipids
Lymphoma D008223 18 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Marek Disease D008380 4 associated lipids
Medulloblastoma D008527 22 associated lipids
Melanoma D008545 69 associated lipids
Myoepithelioma D009208 1 associated lipids
Nasopharyngeal Neoplasms D009303 4 associated lipids
Neoplastic Cells, Circulating D009360 5 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Nerve Degeneration D009410 53 associated lipids
Nervous System Diseases D009422 37 associated lipids
Neuroblastoma D009447 66 associated lipids
Nevus D009506 2 associated lipids
Nose Neoplasms D009669 3 associated lipids
Occupational Diseases D009784 42 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Periodontal Diseases D010510 15 associated lipids
Periodontitis D010518 22 associated lipids
Peritonitis D010538 38 associated lipids
Phenylketonurias D010661 7 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Poultry Diseases D011201 21 associated lipids
Pregnancy in Diabetics D011254 3 associated lipids
Proctitis D011349 1 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

Download all related citations
Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Wasserman L et al. The effect of aloe emodin on the proliferation of a new merkel carcinoma cell line. 2002 Am J Dermatopathol pmid:11803275
Choi J et al. Antinociceptive and anti-rheumatoidal effects of Kalopanax pictus extract and its saponin components in experimental animals. 2002 J Ethnopharmacol pmid:11801382
Jordan IK et al. Constant relative rate of protein evolution and detection of functional diversification among bacterial, archaeal and eukaryotic proteins. 2001 Genome Biol. pmid:11790256
Nancey S et al. [Colonic microflora and cancer]. 2001 Gastroenterol. Clin. Biol. pmid:11787385
Chopin V et al. Sodium butyrate induces P53-independent, Fas-mediated apoptosis in MCF-7 human breast cancer cells. 2002 Br. J. Pharmacol. pmid:11786482
Fabianowska-Majewska K et al. Inhibition of dna methylation by 5-aza-2'-deoxycytidine correlates with induction of K562 cells differentiation. 2000 Adv. Exp. Med. Biol. pmid:11783512
Karagül-Yüceer Y et al. Volatile flavor components of stored nonfat dry milk. 2002 J. Agric. Food Chem. pmid:11782199
Bender A et al. Colonic fermentation as affected by antibiotics and acidic pH: Application of an in vitro model. 2001 Z Gastroenterol pmid:11778150
Tshiyombo TD and Oulton MR Comparative effects of chronic exposure to glucose or sodium butyrate on surfactant development in fetal rabbits. 2001 J Perinat Med pmid:11776678
Bordonaro M et al. Cell type- and promoter-dependent modulation of the Wnt signaling pathway by sodium butyrate. 2002 Int. J. Cancer pmid:11774242
Hashimoto H et al. [The occurrence of a reductase of delta2-carboxylic acids in Clostridium kluyveri with a stereospecificity different from that of butyryl-CoA dehydrogenase (author's transl)]. 1975 Hoppe-Seyler's Z. Physiol. Chem. pmid:1176088
Kang HO et al. Cometabolic biosynthesis of copolyesters consisting of 3-hydroxyvalerate and medium-chain-length 3-hydroxyalkanoates by Pseudomonas sp. DSY-82. 2001 Antonie Van Leeuwenhoek pmid:11759051
Pácha J et al. Effect of cellular differentiation on 11beta-hydroxysteroid dehydrogenase activity in the intestine. 2002 Steroids pmid:11755176
O'Donnell JM et al. Coupling of mitochondrial fatty acid uptake to oxidative flux in the intact heart. 2002 Biophys. J. pmid:11751291
Liu HL and Anthonsen T Enantiopure building blocks for chiral drugs from racemic mixtures of secondary alcohols by combination of lipase catalysis and Mitsunobu esterification. 2002 Chirality pmid:11748796
Giermasz A et al. Potentiated antitumor effects of butyrate and actinomycin D in melanoma model in mice. 2002 Jan-Feb Oncol. Rep. pmid:11748483
Dienel GA et al. Local uptake of (14)C-labeled acetate and butyrate in rat brain in vivo during spreading cortical depression. 2001 J. Neurosci. Res. pmid:11746406
Fukuda M et al. Prebiotic treatment of experimental colitis with germinated barley foodstuff: a comparison with probiotic or antibiotic treatment. 2002 Int. J. Mol. Med. pmid:11744999
Araki Y et al. Oral administration of a product derived from Clostridium butyricum in rats. 2002 Int. J. Mol. Med. pmid:11744996
Honecker VH and Coper H [Stability of amphetaminil. 1. In-vitro studies]. 1975 Arzneimittelforschung pmid:1174051
Paulukat J et al. Expression and release of IL-18 binding protein in response to IFN-gamma. 2001 J. Immunol. pmid:11739524
Kegel KB et al. Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription. 2002 J. Biol. Chem. pmid:11739372
Fang HH and Yu H Mesophilic acidification of gelatinaceous wastewater. 2002 J. Biotechnol. pmid:11738717
Vatin AE and Filatov PP [Pharmacokinetics of C14-olivomycin in the body of mice with lymphosarcoma (L10-1 strain)]. 1975 Antibiotiki pmid:1173211
Holdaway-Clarke TL et al. Cytoplasmic acidification with butyric acid does not alter the ionic conductivity of plasmodesmata. 2001 Protoplasma pmid:11732057
Daubeuf S et al. Differential regulation of gamma-glutamyltransferase mRNAs in four human tumour cell lines. 2001 Biochim. Biophys. Acta pmid:11731087
Guardiola AR and Yao TP Molecular cloning and characterization of a novel histone deacetylase HDAC10. 2002 J. Biol. Chem. pmid:11726666
Reynaert R et al. Influence of serum free fatty acid levels on growth hormone secretion in lactating cows. 1975 J. Endocrinol. pmid:1172520
Ugrinova I et al. In vivo acetylation of HMG1 protein enhances its binding affinity to distorted DNA structures. 2001 Biochemistry pmid:11724579
Brokaw L et al. Supplemental soybean oil or corn for beef heifers grazing summer pasture: effects on forage intake, ruminal fermentation, and site and extent of digestion. 2001 J. Anim. Sci. pmid:11721851
Henney JE Cyberpharmacies and the role of the US Food And Drug Administration. 2001 Jan-Mar J. Med. Internet Res. pmid:11720945
Osada H et al. Heterogeneous transforming growth factor (TGF)-beta unresponsiveness and loss of TGF-beta receptor type II expression caused by histone deacetylation in lung cancer cell lines. 2001 Cancer Res. pmid:11719467
Cao XX et al. Histone deacetylase inhibitor downregulation of bcl-xl gene expression leads to apoptotic cell death in mesothelioma. 2001 Am. J. Respir. Cell Mol. Biol. pmid:11713097
Tuleu C et al. Colonic delivery of sodium butyrate via oral route: acrylic coating design of pellets and in vivo evaluation in rats. 2001 Methods Find Exp Clin Pharmacol pmid:11712644
Pérez G et al. Disturbance of cellular iron uptake and utilisation by aluminium. 2001 J. Inorg. Biochem. pmid:11709209
Frederich M and Balschi JA The relationship between AMP-activated protein kinase activity and AMP concentration in the isolated perfused rat heart. 2002 J. Biol. Chem. pmid:11707445
Gassull MA and Cabré E Nutrition in inflammatory bowel disease. 2001 Curr Opin Clin Nutr Metab Care pmid:11706295
Amin HM et al. Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17). 2001 Br. J. Haematol. pmid:11703323
Santini V et al. Searching for the magic bullet against cancer: the butyrate saga. 2001 Leuk. Lymphoma pmid:11699392
Dunphy CH et al. Acute promyelocytic leukemia, hypogranular variant, with uncharacteristic staining with chloroacetate esterase. 2001 Leuk. Lymphoma pmid:11699210
Loffing-Cueni D et al. Trafficking of GFP-tagged DeltaF508-CFTR to the plasma membrane in a polarized epithelial cell line. 2001 Am. J. Physiol., Cell Physiol. pmid:11698247
Resta-Lenert S et al. Inhibition of epithelial chloride secretion by butyrate: role of reduced adenylyl cyclase expression and activity. 2001 Am. J. Physiol., Cell Physiol. pmid:11698242
Amano J et al. Comparative study of glycosyltransferase activities in Caco-2 cells before and after enterocytic differentiation using lectin-affinity high-performance liquid chromatography. 2001 Arch. Biochem. Biophys. pmid:11697856
Zheng X et al. Synergistic effects of clinically achievable concentrations of 12-O-tetradecanoylphorbol-13-acetate in combination with all-trans retinoic acid, 1alpha,25-dihydroxyvitamin D3, and sodium butyrate on differentiation in HL-60 cells. 2000 Oncol. Res. pmid:11697820
Sultanova N et al. Antioxidant and antimicrobial activities of Tamarix ramosissima. 2001 J Ethnopharmacol pmid:11694365
Fujita M et al. Up-regulation of the ectodermal-neural cortex 1 (ENC1) gene, a downstream target of the beta-catenin/T-cell factor complex, in colorectal carcinomas. 2001 Cancer Res. pmid:11691783
Onori L et al. N-Butyrate rectal transport in cirrhotic patients. 2001 Dig. Dis. Sci. pmid:11680580
Gaschott T et al. Butyrate-induced differentiation of Caco-2 cells is mediated by vitamin D receptor. 2001 Biochem. Biophys. Res. Commun. pmid:11676498
Tsapali DS et al. mRNA levels of the differentiation-associated linker histone variant H1 zero in mitotically active and postmitotic senescent human diploid fibroblast cell populations. 2001 Exp. Gerontol. pmid:11672986
Terao Y et al. Sodium butyrate induces growth arrest and senescence-like phenotypes in gynecologic cancer cells. 2001 Int. J. Cancer pmid:11668507