butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Meslin JC et al. | Differential influence of butyrate concentration on proximal and distal colonic mucosa in rats born germ-free and associated with a strain of Clostridium paraputrificum. | 2001 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:11223399 |
Zaharia V et al. | Effects of short chain fatty acids on colonic Na+ absorption and enzyme activity. | 2001 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:11223395 |
Murray SM et al. | In vitro fermentation characteristics of native and processed cereal grains and potato starch using ileal chyme from dogs. | 2001 | J. Anim. Sci. | pmid:11219453 |
Satyanarayana S et al. | Hypoglycaemic activity of extracts from soft corals of Andaman and Nicobar coasts in rats. | 2000 | Indian J. Exp. Biol. | pmid:11218836 |
Sowa Y and Sakai T | Butyrate as a model for "gene-regulating chemoprevention and chemotherapy.". | 2000 | Biofactors | pmid:11216497 |
Nishimura N et al. | Plasma cholesterol-lowering effect on rats of dietary fiber extracted from immature plants. | 2000 | Biosci. Biotechnol. Biochem. | pmid:11210115 |
Kilcawley KN et al. | A survey of lipolytic and glycolytic end-products in commercial Cheddar enzyme-modified cheese. | 2001 | J. Dairy Sci. | pmid:11210051 |
Mandal M et al. | Butyric acid induces apoptosis by up-regulating Bax expression via stimulation of the c-Jun N-terminal kinase/activation protein-1 pathway in human colon cancer cells. | 2001 | Gastroenterology | pmid:11208715 |
Kanauchi O et al. | Dietary fiber fraction of germinated barley foodstuff attenuated mucosal damage and diarrhea, and accelerated the repair of the colonic mucosa in an experimental colitis. | 2001 | J. Gastroenterol. Hepatol. | pmid:11207896 |
Lee CT et al. | Differential effects of adenovirus-p16 on bladder cancer cell lines can be overcome by the addition of butyrate. | 2001 | Clin. Cancer Res. | pmid:11205911 |
Kurita-Ochiai T et al. | Butyric-acid-induced apoptosis in murine thymocytes and splenic T- and B-cells occurs in the absence of p53. | 2000 | J. Dent. Res. | pmid:11201044 |
Rajendran VM and Binder HJ | Characterization and molecular localization of anion transporters in colonic epithelial cells. | 2000 | Ann. N. Y. Acad. Sci. | pmid:11193571 |
Pedersen G et al. | Cultures of human colonic epithelial cells isolated from endoscopical biopsies from patients with inflammatory bowel disease. Effect of IFNgamma, TNFalpha and IL-1beta on viability, butyrate oxidation and IL-8 secretion. | 2000 | Autoimmunity | pmid:11191284 |
Taddei A and Rosas-Romero AJ | Bioactivity studies of extracts from Tridax procumbens. | 2000 | Phytomedicine | pmid:11185735 |
Hirakawa T et al. | Metabolism of benzo[A]pyrene and the related enzyme activities in hamster embryo cells. | 1979 | Chem. Biol. Interact. | pmid:111804 |
Giermasz A et al. | Antitumor activity of tributyrin in murine melanoma model. | 2001 | Cancer Lett. | pmid:11179828 |
Martin LJ et al. | Potato and high-amylose maize starches are not equivalent producers of butyrate for the colonic mucosa. | 2000 | Br. J. Nutr. | pmid:11177182 |
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Glinghammar B and Rafter J | Colonic luminal contents induce cyclooxygenase 2 transcription in human colon carcinoma cells. | 2001 | Gastroenterology | pmid:11159881 |
Kamitani H et al. | Expression of 15-lipoxygenase-1 is regulated by histone acetylation in human colorectal carcinoma. | 2001 | Carcinogenesis | pmid:11159758 |
Rychkov GY et al. | Interaction of hydrophobic anions with the rat skeletal muscle chloride channel ClC-1: effects on permeation and gating. | 2001 | J. Physiol. (Lond.) | pmid:11158270 |
Kitazono M et al. | Construction of gene therapy vectors targeting thyroid cells: enhancement of activity and specificity with histone deacetylase inhibitors and agents modulating the cyclic adenosine 3',5'-monophosphate pathway and demonstration of activity in follicular and anaplastic thyroid carcinoma cells. | 2001 | J. Clin. Endocrinol. Metab. | pmid:11158054 |
Mathas S et al. | Anti-CD20- and B-cell receptor-mediated apoptosis: evidence for shared intracellular signaling pathways. | 2000 | Cancer Res. | pmid:11156427 |
Binnemans K et al. | Structure and mesomorphism of neodymium(III) alkanoates. | 2000 | Inorg Chem | pmid:11151495 |
Ling SC and Griffiths AM | Nutrition in inflammatory bowel disease. | 2000 | Curr Opin Clin Nutr Metab Care | pmid:11151077 |
Mimura Y et al. | Butyrate increases production of human chimeric IgG in CHO-K1 cells whilst maintaining function and glycoform profile. | 2001 | J. Immunol. Methods | pmid:11150551 |
Kitazono M et al. | Reversal of LRP-associated drug resistance in colon carcinoma SW-620 cells. | 2001 | Int. J. Cancer | pmid:11149411 |
Jackson SK et al. | Induction of anergy in Th1 cells associated with increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1. | 2001 | J. Immunol. | pmid:11145672 |
Hamada T et al. | Suppression of adjuvant arthritis of rats by a novel matrix metalloproteinase-inhibitor. | 2000 | Br. J. Pharmacol. | pmid:11139426 |
Campos MG et al. | Galphimia glauca organic fraction antagonizes LTD(4)-induced contraction in guinea pig airways. | 2001 | J Ethnopharmacol | pmid:11137344 |
Zhang JS et al. | Keratin 23 (K23), a novel acidic keratin, is highly induced by histone deacetylase inhibitors during differentiation of pancreatic cancer cells. | 2001 | Genes Chromosomes Cancer | pmid:11135429 |
Tikhonova GP et al. | [Effect of hypokinesia and lowered barometric pressure on the tolerance of animals to the action of ethyl acetate]. | 1975 Jan-Feb | Kosm Biol Aviakosm Med | pmid:1113489 |
Avivi-Green C et al. | Apoptosis cascade proteins are regulated in vivo by high intracolonic butyrate concentration: correlation with colon cancer inhibition. | 2000 | Oncol. Res. | pmid:11132927 |
Whitfield FB et al. | Role of Yersinia intermedia and Pseudomonas putida in the development of a fruity off-flavour in pasteurized milk. | 2000 | J. Dairy Res. | pmid:11131069 |
Adhikari D et al. | Pretreatment of endometrial carcinoma cell lines with butyrate results in upregulation of Bax and correlates with potentiation of radiation induced cell kill. | 2000 Sep-Oct | In Vivo | pmid:11125544 |
Choi HS et al. | The effect of acidosis on systolic Ca2+ and sarcoplasmic reticulum calcium content in isolated rat ventricular myocytes. | 2000 | J. Physiol. (Lond.) | pmid:11118496 |
Perrin P et al. | Only fibres promoting a stable butyrate producing colonic ecosystem decrease the rate of aberrant crypt foci in rats. | 2001 | Gut | pmid:11115823 |
Follesa P et al. | Pivagabine-induced increases in the abundance of CRF mRNA in the cerebral cortex and hypothalamus of rats. | 2000 | Brain Res. Mol. Brain Res. | pmid:11113531 |
Ost TW et al. | Rational re-design of the substrate binding site of flavocytochrome P450 BM3. | 2000 | FEBS Lett. | pmid:11113461 |
Davis T et al. | Histone deacetylase inhibitors decrease proliferation and modulate cell cycle gene expression in normal mammary epithelial cells. | 2000 | Clin. Cancer Res. | pmid:11106251 |
Bach Knudsen KE et al. | Quantification of the absorption of nutrients derived from carbohydrate assimilation: model experiment with catheterised pigs fed on wheat- or oat-based rolls. | 2000 | Br. J. Nutr. | pmid:11103215 |
Hino T et al. | Drug release from w/o/w emulsions prepared with different chitosan salts and concomitant creaming up. | 2000 | J Control Release | pmid:11102681 |
Halicka HD et al. | Induction of differentiation of leukaemic (HL-60) or prostate cancer (LNCaP, JCA-1) cells potentiates apoptosis triggered by onconase. | 2000 | Cell Prolif. | pmid:11101012 |
Choo-Kang LR and Zeitlin PL | Type I, II, III, IV, and V cystic fibrosis transmembrane conductance regulator defects and opportunities for therapy. | 2000 | Curr Opin Pulm Med | pmid:11100963 |
Venkatraman A et al. | Increased permeability in dextran sulphate colitis in rats: time course of development and effect of butyrate. | 2000 | Scand. J. Gastroenterol. | pmid:11099058 |