butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lee E et al. | Involvement of histone hyperacetylation in triggering DNA fragmentation of rat thymocytes undergoing apoptosis. | 1996 | FEBS Lett. | pmid:8898091 |
Nordgaard I et al. | Colonic production of butyrate in patients with previous colonic cancer during long-term treatment with dietary fibre (Plantago ovata seeds). | 1996 | Scand. J. Gastroenterol. | pmid:8898423 |
Steinhart AH et al. | Treatment of left-sided ulcerative colitis with butyrate enemas: a controlled trial. | 1996 | Aliment. Pharmacol. Ther. | pmid:8899080 |
Campbell CG et al. | Efficiency of D- vs L-methionine utilization by growing steers. | 1996 | J. Anim. Sci. | pmid:8904718 |
Grdisa M and White MK | Expression of glyceraldehyde-3-phosphate dehydrogenase during differentiation of HD3 cells. | 1996 | Eur. J. Cell Biol. | pmid:8905295 |
Hanski C et al. | Fucosyltransferase III and sialyl-Le(x) expression correlate in cultured colon carcinoma cells but not in colon carcinoma tissue. | 1996 | Glycoconj. J. | pmid:8909999 |
Mondal D and Agrawal KC | Effect of HIV type 1 Tat protein on butyric acid-induced differentiation in a hematopoietic progenitor cell line. | 1996 | AIDS Res. Hum. Retroviruses | pmid:8911578 |
Fiorino AS and Zvibel I | Disruption of cell-cell adhesion in the presence of sodium butyrate activates expression of the 92 kDa type IV collagenase in MDCK cells. | 1996 | Cell Biol. Int. | pmid:8931316 |
Tada S et al. | Reduction of LAK-sensitivity and changes in antigen expression on hepatoma cells by sodium butyrate. | 1996 | Cancer Biochem. Biophys. | pmid:8937741 |
MacCormac LP and Grundy JE | Human cytomegalovirus induces an Fc gamma receptor (Fc gammaR) in endothelial cells and fibroblasts that is distinct from the human cellular Fc gammaRs. | 1996 | J. Infect. Dis. | pmid:8940203 |
Morrone G et al. | Differential regulation of the expression of interleukin-2 receptor gamma-chain during the in vitro differentiation of human myeloid cells. | 1995 | Biochem. J. | pmid:8948450 |
Lallemand F et al. | Direct inhibition of the expression of cyclin D1 gene by sodium butyrate. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8954100 |
Benoit NE and Wade WF | Increased inhibition of proliferation of human B cell lymphomas following ligation of CD40, and either CD19, CD20, CD95 or surface immunoglobulin. | 1996 | Immunopharmacology | pmid:8956976 |
Buckley AR et al. | Alterations in pim-1 and c-myc expression associated with sodium butyrate-induced growth factor dependency in autonomous rat Nb2 lymphoma cells. | 1996 | Cell Growth Differ. | pmid:8959340 |
Böhmig GA et al. | Induction of alloantigen-specific hyporesponsiveness in vitro by n-butyrate: antagonistic effect of cyclosporin A. | 1996 | Transpl. Int. | pmid:8959855 |
D'Argenio G et al. | Butyrate enemas in experimental colitis and protection against large bowel cancer in a rat model. | 1996 | Gastroenterology | pmid:8964397 |
Li S et al. | The C-terminal Src kinase (Csk) is widely expressed, active in HT-29 cells that contain activated Src, and its expression is downregulated in butyrate-treated SW620 cells. | 1996 | Cell Biol. Int. | pmid:8979366 |
Miller G et al. | Selective switch between latency and lytic replication of Kaposi's sarcoma herpesvirus and Epstein-Barr virus in dually infected body cavity lymphoma cells. | 1997 | J. Virol. | pmid:8985352 |
Forster RJ et al. | 16S rDNA analysis of Butyrivibrio fibrisolvens: phylogenetic position and relation to butyrate-producing anaerobic bacteria from the rumen of white-tailed deer. | 1996 | Lett. Appl. Microbiol. | pmid:8987694 |
Immig I et al. | Attempts to induce reductive acetogenesis into a sheep rumen. | 1996 | Arch Tierernahr | pmid:8988318 |
Chacin J et al. | Role of oxalacetate in lipoate effect on frog gastric mucosa. | 1976 | Am. J. Physiol. | pmid:8990 |
Plaisancié P et al. | Luminal peptide YY-releasing factors in the isolated vascularly perfused rat colon. | 1996 | J. Endocrinol. | pmid:8994387 |
Götzinger N et al. | Regulation of human endogenous retrovirus-K Gag expression in teratocarcinoma cell lines and human tumours. | 1996 | J. Gen. Virol. | pmid:9000088 |
Hague A et al. | The role of butyrate in human colonic epithelial cells: an energy source or inducer of differentiation and apoptosis? | 1996 | Proc Nutr Soc | pmid:9004335 |
Rabizadeh E et al. | Esterase inhibitors diminish the modulation of gene expression by butyric acid derivative, pivaloyloxymethyl butyrate (AN-9). | 1996 | Isr. J. Med. Sci. | pmid:9007151 |
Hales RH | Gas-permeable cellulose acetate butyrate (CAB) contact lenses. | 1977 | Ann Ophthalmol | pmid:900727 |
Ishiguro K and Sartorelli AC | The response of IL-3 dependent B6SUtA bone marrow cells to both erythropoietin and chemical inducers of differentiation. | 1996 | Cancer Lett. | pmid:9018107 |
Higgins PJ et al. | P52PAI-1 gene expression in butyrate-induced flat revertants of v-ras-transformed rat kidney cells: mechanism of induction and involvement in the morphological response. | 1997 | Biochem. J. | pmid:9020877 |
Oster T et al. | Gene transfer technologies for the production of enzyme and protein reference materials. | 1997 | Clin. Chim. Acta | pmid:9028623 |
Doreau M and Ottou JF | Influence of niacin supplementation on in vivo digestibility and ruminal digestion in dairy cows. | 1996 | J. Dairy Sci. | pmid:9029363 |
Hersey SJ | Metabolic changes associated with gastric stimulation. | 1977 | Gastroenterology | pmid:902957 |
Brun T et al. | Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1. | 1997 | Diabetes | pmid:9032094 |
Nicholas J et al. | A single 13-kilobase divergent locus in the Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genome contains nine open reading frames that are homologous to or related to cellular proteins. | 1997 | J. Virol. | pmid:9032328 |
Rogler LE | Selective bipotential differentiation of mouse embryonic hepatoblasts in vitro. | 1997 | Am. J. Pathol. | pmid:9033273 |
Aukema HM et al. | Butyrate alters activity of specific cAMP-receptor proteins in a transgenic mouse colonic cell line. | 1997 | J. Nutr. | pmid:9040538 |
Hass R et al. | Lack of butyrate is associated with induction of Bax and subsequent apoptosis in the proximal colon of guinea pig. | 1997 | Gastroenterology | pmid:9041249 |
Hague A et al. | Butyrate acts as a survival factor for colonic epithelial cells: further fuel for the in vivo versus in vitro debate. | 1997 | Gastroenterology | pmid:9041270 |
Niederman R et al. | Short-chain carboxylic acid concentration in human gingival crevicular fluid. | 1997 | J. Dent. Res. | pmid:9042080 |
Chapman MA et al. | Metabolic adaptation of terminal ileal mucosa after construction of an ileoanal pouch. | 1997 | Br J Surg | pmid:9043459 |
Mandal M et al. | Bcl-2 deregulation leads to inhibition of sodium butyrate-induced apoptosis in human colorectal carcinoma cells. | 1997 | Carcinogenesis | pmid:9054611 |
Niitsu N et al. | AML1a but not AML1b inhibits erythroid differentiation induced by sodium butyrate and enhances the megakaryocytic differentiation of K562 leukemia cells. | 1997 | Cell Growth Differ. | pmid:9056674 |
Bordonaro M and Augenlicht L | The 3' untranslated region of the carcinoembryonic antigen gene plays a minimal role in the regulation of gene expression. | 1997 | Cell Growth Differ. | pmid:9056678 |
Scheppach W et al. | Histological changes in the colonic mucosa following irrigation with short-chain fatty acids. | 1997 | Eur J Gastroenterol Hepatol | pmid:9058627 |
Huang N et al. | Inhibition of IL-8 gene expression in Caco-2 cells by compounds which induce histone hyperacetylation. | 1997 | Cytokine | pmid:9067093 |
Stein TP et al. | Weight loss, the gut and the inflammatory response in aids patients. | 1997 | Cytokine | pmid:9071566 |
Skretting G et al. | Sodium butyrate inhibits the expression of the human lecithin: cholesterol acyltransferase gene in HepG2 cells by a post-transcriptional mechanism. | 1997 | FEBS Lett. | pmid:9074647 |
Sun SH et al. | Altered phospholipid metabolism in sodium butyrate-induced differentiation of C6 glioma cells. | 1997 | Lipids | pmid:9076664 |
Litchfield TM and Sauer GR | Metallothionein induction in calcifying growth plate cartilage chondrocytes. | 1996 | Connect. Tissue Res. | pmid:9084657 |
Moulding D et al. | Regulation of neutrophil apoptosis by sodium butyrate. | 1996 | Biologicals | pmid:9088543 |
Niki S et al. | [A case of hepatocellular carcinoma associated with autoimmune hepatitis and increased scintigraphy of liver accumulation]. | 1997 | Nihon Shokakibyo Gakkai Zasshi | pmid:9095644 |