butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cui Y et al. | Interference of the Histone Deacetylase Inhibits Pollen Germination and Pollen Tube Growth in Picea wilsonii Mast. | 2015 | PLoS ONE | pmid:26710276 |
Saito K et al. | Modulation of Cytokine Secretion Allows CD4 T Cells Secreting IL-10 and IL-17 to Simultaneously Participate in Maintaining Tolerance and Immunity. | 2015 | PLoS ONE | pmid:26709703 |
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Muñoz-Rugeles L and Alvarez-Idaboy JR | A proton-electron sequential transfer mechanism: theoretical evidence about its biological relevance. | 2015 | Phys Chem Chem Phys | pmid:26456543 |
Sari O et al. | Synthesis of dihydropyrimidine α,γ-diketobutanoic acid derivatives targeting HIV integrase. | 2015 | Eur J Med Chem | pmid:26451771 |
Jin CJ et al. | Supplementation of sodium butyrate protects mice from the development of non-alcoholic steatohepatitis (NASH). | 2015 | Br. J. Nutr. | pmid:26450277 |
Nasser Al-Shorgani NK et al. | Improvement of the butanol production selectivity and butanol to acetone ratio (B:A) by addition of electron carriers in the batch culture of a new local isolate of Clostridium acetobutylicum YM1. | 2015 | Anaerobe | pmid:26439644 |
Wang L et al. | Fermentation of sweet sorghum derived sugars to butyric acid at high titer and productivity by a moderate thermophile Clostridium thermobutyricum at 50°C. | 2015 | Bioresour. Technol. | pmid:26432057 |
Baroi GN et al. | Butyric acid fermentation from pretreated and hydrolysed wheat straw by an adapted Clostridium tyrobutyricum strain. | 2015 | Microb Biotechnol | pmid:26230610 |
Zhong Y et al. | Barley malt increases hindgut and portal butyric acid, modulates gene expression of gut tight junction proteins and Toll-like receptors in rats fed high-fat diets, but high advanced glycation end-products partially attenuate the effects. | 2015 | Food Funct | pmid:26227569 |
Sandoval PY et al. | Checkpoint Activation of an Unconventional DNA Replication Program in Tetrahymena. | 2015 | PLoS Genet. | pmid:26218270 |
Valvassori SS et al. | Sodium Butyrate, a Histone Deacetylase Inhibitor, Reverses Behavioral and Mitochondrial Alterations in Animal Models of Depression Induced by Early- or Late-life Stress. | 2015 | Curr Neurovasc Res | pmid:26216027 |
Qaisrani SN et al. | Diet structure, butyric acid, and fermentable carbohydrates influence growth performance, gut morphology, and cecal fermentation characteristics in broilers. | 2015 | Poult. Sci. | pmid:26175052 |
Xu H et al. | Sodium butyrate stimulates NHE8 expression via its role on activating NHE8 basal promoter activity. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:26159698 |
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Malago JJ and Sangu CL | Intraperitoneal administration of butyrate prevents the severity of acetic acid colitis in rats. | 2015 | J Zhejiang Univ Sci B | pmid:25743124 |
Gonnella R et al. | PKC theta and p38 MAPK activate the EBV lytic cycle through autophagy induction. | 2015 | Biochim. Biophys. Acta | pmid:25827954 |
Shimoyama T et al. | Study of the mechanisms of a Japanese traditional fermented medicine in the improvement of constipation. | 2015 | J. Gastroenterol. Hepatol. | pmid:25827805 |
Huang YW et al. | Brain isoform glycogen phosphorylase as a novel hepatic progenitor cell marker. | 2015 | PLoS ONE | pmid:25826279 |
Chen L et al. | Free and bound volatile chemicals in mulberry (Morus atropurpurea Roxb.). | 2015 | J. Food Sci. | pmid:25817411 |
Cueno ME et al. | High butyric acid amounts induce oxidative stress, alter calcium homeostasis, and cause neurite retraction in nerve growth factor-treated PC12 cells. | 2015 | Cell Stress Chaperones | pmid:25808460 |
Kanika G et al. | Sodium Butyrate Ameliorates L-Arginine-Induced Pancreatitis and Associated Fibrosis in Wistar Rat: Role of Inflammation and Nitrosative Stress. | 2015 | J. Biochem. Mol. Toxicol. | pmid:25774002 |
Cao QF et al. | TRPM2 mediates histone deacetylase inhibition-induced apoptosis in bladder cancer cells. | 2015 | Cancer Biother. Radiopharm. | pmid:25760728 |
Mackmull MT et al. | Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs). | 2015 | Mol. Cell Proteomics | pmid:25755299 |
Rodrigues MF et al. | Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin A on the energy metabolism of breast cancer cells. | 2015 | J. Cell. Biochem. | pmid:25510910 |
Varela RB et al. | Sodium butyrate and mood stabilizers block ouabain-induced hyperlocomotion and increase BDNF, NGF and GDNF levels in brain of Wistar rats. | 2015 | J Psychiatr Res | pmid:25467060 |
Turon V et al. | Use of fermentative metabolites for heterotrophic microalgae growth: Yields and kinetics. | 2015 | Bioresour. Technol. | pmid:25459841 |
Zgorzynska E et al. | Docosahexaenoic acid attenuates oxidative stress and protects human gingival fibroblasts against cytotoxicity induced by hydrogen peroxide and butyric acid. | 2015 | Arch. Oral Biol. | pmid:25455128 |
Lee C et al. | Effect of 2-hydroxy-4-methylthio-butanoic acid on ruminal fermentation, bacterial distribution, digestibility, and performance of lactating dairy cows. | 2015 | J. Dairy Sci. | pmid:25434334 |
Lopes-Borges J et al. | Histone deacetylase inhibitors reverse manic-like behaviors and protect the rat brain from energetic metabolic alterations induced by ouabain. | 2015 | Pharmacol. Biochem. Behav. | pmid:25433326 |
Simon-O'Brien E et al. | The histone deacetylase inhibitor sodium butyrate decreases excessive ethanol intake in dependent animals. | 2015 | Addict Biol | pmid:25041570 |
Katsou E et al. | Coupling the treatment of low strength anaerobic effluent with fermented biowaste for nutrient removal via nitrite. | 2015 | J. Environ. Manage. | pmid:25463576 |
Xiong XR et al. | Sodium butyrate improves the cloned yak embryo viability and corrects gene expression patterns. | 2015 | Zygote | pmid:23759515 |
Stertz L et al. | Histone deacetylase activity and brain-derived neurotrophic factor (BDNF) levels in a pharmacological model of mania. | 2014 Jan-Mar | Rev Bras Psiquiatr | pmid:24346357 |
Lu R et al. | Effect of non-surgical periodontal treatment on short chain fatty acid levels in gingival crevicular fluid of patients with generalized aggressive periodontitis. | 2014 | J. Periodont. Res. | pmid:25340203 |
Jin H et al. | Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease. | 2014 | J. Biol. Chem. | pmid:25342743 |
Weber TE et al. | Effects of dietary humic and butyric acid on growth performance and response to lipopolysaccharide in young pigs. | 2014 | J. Anim. Sci. | pmid:25023805 |
Nakata S et al. | Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity. | 2014 | Int. J. Oncol. | pmid:25017791 |
Gutiérrez Acosta OB et al. | Acetone utilization by sulfate-reducing bacteria: draft genome sequence of Desulfococcus biacutus and a proteomic survey of acetone-inducible proteins. | 2014 | BMC Genomics | pmid:25012398 |
Farkas O et al. | Effects of Lactobacillus plantarum 2142 and sodium n-butyrate in lipopolysaccharide-triggered inflammation: comparison of a porcine intestinal epithelial cell line and primary hepatocyte monocultures with a porcine enterohepatic co-culture system. | 2014 | J. Anim. Sci. | pmid:24987069 |
Krokowicz L et al. | Microencapsulated sodium butyrate administered to patients with diverticulosis decreases incidence of diverticulitis--a prospective randomized study. | 2014 | Int J Colorectal Dis | pmid:24343275 |
Sanchez R et al. | Differential abundance of IGF1, bile acids, and the genes involved in their signaling in the dominant follicle microenvironment of lactating cows and nulliparous heifers. | 2014 | Theriogenology | pmid:24503106 |
Leon Carrion S et al. | Combined treatment with sodium butyrate and PD153035 enhances keratinocyte differentiation. | 2014 | Exp. Dermatol. | pmid:24451036 |
Liu Y et al. | Sodium butyrate enhances the acidic isoform content of recombinant human erythropoietin produced by Chinese hamster ovary cells. | 2014 | Biotechnol. Lett. | pmid:24557070 |
Hu X et al. | Histone deacetylase inhibitor sodium butyrate promotes the osteogenic differentiation of rat adipose-derived stem cells. | 2014 | Dev. Growth Differ. | pmid:24494796 |
Meehan CJ and Beiko RG | A phylogenomic view of ecological specialization in the Lachnospiraceae, a family of digestive tract-associated bacteria. | 2014 | Genome Biol Evol | pmid:24625961 |
Pan Y et al. | Potential usefulness of baculovirus-mediated sodium-iodide symporter reporter gene as non-invasively gene therapy monitoring in liver cancer cells: an in vitro evaluation. | 2014 | Technol. Cancer Res. Treat. | pmid:23919394 |