| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diverticulitis | D004238 | 1 associated lipids |
| Salivary Gland Neoplasms | D012468 | 1 associated lipids |
| Astigmatism | D001251 | 1 associated lipids |
| Anaplasia | D000708 | 1 associated lipids |
| Trophoblastic Neoplasms | D014328 | 1 associated lipids |
| Diverticulitis, Colonic | D004239 | 1 associated lipids |
| Aphakia, Postcataract | D001036 | 1 associated lipids |
| Diverticulosis, Colonic | D043963 | 1 associated lipids |
| Facial Injuries | D005151 | 1 associated lipids |
| Gastrinoma | D015408 | 1 associated lipids |
| Myoepithelioma | D009208 | 1 associated lipids |
| Proctitis | D011349 | 1 associated lipids |
| Intestinal Neoplasms | D007414 | 2 associated lipids |
| Hemorrhoids | D006484 | 2 associated lipids |
| Lymphoma, AIDS-Related | D016483 | 2 associated lipids |
| Sarcoma, Avian | D001357 | 2 associated lipids |
| Dentin, Secondary | D003809 | 2 associated lipids |
| Colorectal Neoplasms, Hereditary Nonpolyposis | D003123 | 2 associated lipids |
| Nevus | D009506 | 2 associated lipids |
| Granuloma, Lethal Midline | D006103 | 2 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Blusztajn JK et al. | Acetylcholine synthesis and release is enhanced by dibutyryl cyclic AMP in a neuronal cell line derived from mouse septum. | 1992 | J. Neurosci. | pmid:1312135 |
| Chang YF et al. | Effect of sodium butyrate on glucocorticoid-sensitive and -resistant P1798 lymphosarcoma. | 1992 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:1312378 |
| Kashtan H et al. | Colonic fermentation and markers of colorectal-cancer risk. | 1992 | Am. J. Clin. Nutr. | pmid:1312764 |
| Sembries S et al. | Effects of dietary fibre-rich juice colloids from apple pomace extraction juices on intestinal fermentation products and microbiota in rats. | 2003 | Br. J. Nutr. | pmid:13129467 |
| Miranda-Tello E et al. | Garciella nitratireducens gen. nov., sp. nov., an anaerobic, thermophilic, nitrate- and thiosulfate-reducing bacterium isolated from an oilfield separator in the Gulf of Mexico. | 2003 | Int. J. Syst. Evol. Microbiol. | pmid:13130040 |
| Pouillart P et al. | [Protective activity of monoacetone glucose 3-butyrate, prodrug of n-butyric acid, against the fatal effect of encephalomyocarditis virus in mice]. | 1992 | C. R. Acad. Sci. III, Sci. Vie | pmid:1313734 |
| Shah S et al. | n-butyrate reduces the expression of beta-galactoside alpha 2,6-sialyltransferase in Hep G2 cells. | 1992 | J. Biol. Chem. | pmid:1316908 |
| Lei KJ et al. | Immortalization of virus-free human placental cells that express tissue-specific functions. | 1992 | Mol. Endocrinol. | pmid:1318503 |
| Maiyar AC and Norman AW | Effects of sodium butyrate on 1,25-dihydroxyvitamin D3 receptor activity in primary chick kidney cells. | 1992 | Mol. Cell. Endocrinol. | pmid:1322333 |
| Goldberg YP et al. | Elevation of large-T antigen production by sodium butyrate treatment of SV40-transformed WI-38 fibroblasts. | 1992 | J. Cell. Biochem. | pmid:1322917 |
| Johnston LA et al. | Sodium butyrate inhibits myogenesis by interfering with the transcriptional activation function of MyoD and myogenin. | 1992 | Mol. Cell. Biol. | pmid:1328872 |
| McCafferty DM and Zeitlin IJ | Inhibition of butyric acid-induced colitis in mice by 16,16-dimethyl prostaglandin E2. | 1992 | Agents Actions | pmid:1332452 |
| Le Ruyet P et al. | Influence of dietary fiber and buffer value index on the ruminal milieu of lactating dairy cows. | 1992 | J. Dairy Sci. | pmid:1333496 |
| Tucker WB et al. | Sodium bicarbonate or multielement buffer via diet or rumen: effects on performance and acid-base status of lactating cows. | 1992 | J. Dairy Sci. | pmid:1333497 |
| BRYANT MP and SMALL N | The anaerobic monotrichous butyric acid-producing curved rod-shaped bacteria of the rumen. | 1956 | J. Bacteriol. | pmid:13345769 |
| Kaptein A et al. | Butyrate stimulates the secretion of apolipoprotein A-I and apolipoprotein B-100 in Hep G2 cells by different mechanisms. | 1992 | Clin. Biochem. | pmid:1337018 |
| Kondoh N et al. | Differential expression of S19 ribosomal protein, laminin-binding protein, and human lymphocyte antigen class I messenger RNAs associated with colon carcinoma progression and differentiation. | 1992 | Cancer Res. | pmid:1339304 |
| Kristev A et al. | Effects of the butyric short-chain fatty acid on the bioelectric brain activity of rabbits. | 1992 | Folia Med (Plovdiv) | pmid:1339775 |
| Parekh D et al. | Sodium butyrate stimulates polyamine biosynthesis in colon cancer cells. | 1992 | Surg Oncol | pmid:1341266 |
| Rius C and Aller P | Vimentin expression as a late event in the in vitro differentiation of human promonocytic cells. | 1992 | J. Cell. Sci. | pmid:1352781 |
| Bates SE et al. | Modulation of P-glycoprotein phosphorylation and drug transport by sodium butyrate. | 1992 | Biochemistry | pmid:1352990 |
| Gentile V et al. | Expression of tissue transglutaminase in Balb-C 3T3 fibroblasts: effects on cellular morphology and adhesion. | 1992 | J. Cell Biol. | pmid:1356992 |
| GRAY FV | Bacterial synthesis of butyric acid in the rumen of the sheep. | 1958 | J. Bacteriol. | pmid:13575400 |
| Kalachniuk GI et al. | [Glutamine metabolism by rumen microorganisms: effect of monensin]. | 1992 Jul-Aug | Ukr. Biokhim. Zh. | pmid:1360177 |
| Takahashi H et al. | Alteration of melanoma melanogenesis by phenotypic modifiers. | 1992 | J. Dermatol. | pmid:1363429 |
| Yoshida M et al. | Effect of hexafluoro-1,25-dihydroxyvitamin D3 and sodium butyrate combination on differentiation and proliferation of HL-60 leukemia cells. | 1992 Nov-Dec | Anticancer Res. | pmid:1363510 |
| CURTIS DR et al. | The depression of spinal neurones by gamma-amino-n-butyric acid and beta-alanine. | 1959 | J. Physiol. (Lond.) | pmid:13655226 |
| Hertzberg S et al. | Alginate as immobilization matrix and stabilizing agent in a two-phase liquid system: application in lipase-catalysed reactions. | 1992 | Enzyme Microb. Technol. | pmid:1367810 |
| Orchel A et al. | Quantification of p21 gene expression in Caco-2 cells treated with sodium butyrate using real-time reverse transcription-PCR (RT-PCR) assay. | Acta Pol Pharm | pmid:13678314 | |
| Rahmani M et al. | Inhibition of PI-3 kinase sensitizes human leukemic cells to histone deacetylase inhibitor-mediated apoptosis through p44/42 MAP kinase inactivation and abrogation of p21(CIP1/WAF1) induction rather than AKT inhibition. | 2003 | Oncogene | pmid:13679862 |
| Tzortzis G et al. | In vitro evaluation of the fermentation properties of galactooligosaccharides synthesised by alpha-galactosidase from Lactobacillus reuteri. | 2004 | Appl. Microbiol. Biotechnol. | pmid:13680200 |
| Yamada K et al. | Effects of butyrate on cell cycle progression and polyploidization of various types of mammalian cells. | 1992 | Biosci. Biotechnol. Biochem. | pmid:1368839 |
| Palermo DP et al. | Production of analytical quantities of recombinant proteins in Chinese hamster ovary cells using sodium butyrate to elevate gene expression. | 1991 | J. Biotechnol. | pmid:1369310 |
| Chen CY et al. | Regulatory sequences controlling short chain fatty acid metabolism in Escherichia coli. | 1991 | SAAS Bull. Biochem. Biotechnol. | pmid:1369456 |
| Cockett MI et al. | High level expression of tissue inhibitor of metalloproteinases in Chinese hamster ovary cells using glutamine synthetase gene amplification. | 1990 | Biotechnology (N.Y.) | pmid:1369995 |
| Witte MM et al. | Repression of SV40 T oncoprotein expression by DMSO. | 1992 | J. Cell. Physiol. | pmid:1373148 |
| KUMAR S et al. | Location of butyric acid in bovine milk triglycerides. | 1960 | Biochim. Biophys. Acta | pmid:13755089 |
| Tsukamoto A et al. | Increased assembly of cytoskeletal proteins associated with the transformation of human liver cells into fibroblast-like cells. | 1992 | Experientia | pmid:1376281 |
| Dyson JE et al. | The effect of sodium butyrate on the growth characteristics of human cervix tumour cells. | 1992 | Br. J. Cancer | pmid:1377482 |
| Hall AK | Influence of cyclic AMP and serum factors upon expression of a retinoid-responsive gene in neuroblastoma cells. | 1992 | J. Mol. Neurosci. | pmid:1378294 |
| BRINLEY FJ et al. | Effect of gamma-amino butyric acid (GABA) on K42 outflux from rabbit cortex. | 1960 | J. Neurophysiol. | pmid:13804481 |
| Watanabe T et al. | Alteration of phosphotyrosine-containing proteins at the early stage of erythroid differentiation of mouse erythroleukemia (MEL) cells. | 1992 | J. Biol. Chem. | pmid:1380959 |
| Bruce JH et al. | Effects of cyclic AMP and butyrate on cell cycle, DNA, RNA, and purine synthesis of cultured astrocytes. | 1992 | Neurochem. Res. | pmid:1381055 |
| Biard DS et al. | Flow cytometric detection of drugs altering the DNA methylation pattern. | 1992 | Cancer Res. | pmid:1382840 |
| GULATI OD and STANTON HC | Some effects on the central nervous system of gamma-amino-n-butyric acid (GABA) and certain related amino acids administered systemically and intracerebrally to mice. | 1960 | J. Pharmacol. Exp. Ther. | pmid:13830242 |
| STANTON HC and WOODHOUSE FH | The effect of gamma-amino-n-butyric acid and some related compounds on the cardiovascular system of anesthetized dogs. | 1960 | J. Pharmacol. Exp. Ther. | pmid:13833799 |
| Seagrave JC et al. | Intracellular pH changes induced by exposure to weak acids and bases in submandibular cells of early postnatal rats. | 1992 | Arch. Oral Biol. | pmid:1384459 |
| Perey L et al. | Effects of differentiating agents on cell surface expression of the breast carcinoma-associated DF3-P epitope. | 1992 | Cancer Res. | pmid:1384960 |
| McDonagh KT et al. | Hydroxyurea-induced HbF production in anemic primates: augmentation by erythropoietin, hematopoietic growth factors, and sodium butyrate. | 1992 | Exp. Hematol. | pmid:1385194 |
| BINDMAN LJ et al. | The nonselective blocking action of gamma-amino-butyric acid on the sensory cerebral cortex of the rat. | 1962 | J. Physiol. (Lond.) | pmid:13869242 |
| NASU H and SAKAMOTO Y | Studies on the hydroxylation of the benzene moiety of the indole nucleus of indole compounds. III. On the enzymatic formatin of 6-hydroxyindole-3-butyric acid. | 1962 | J. Biochem. | pmid:13937651 |
| Gordon MJ and Crabtree B | The effects of propionate and butyrate on acetate metabolism in rat hepatocytes. | 1992 | Int. J. Biochem. | pmid:1397495 |
| Chow JC and Jesse BW | Interactions between gluconeogenesis and fatty acid oxidation in isolated sheep hepatocytes. | 1992 | J. Dairy Sci. | pmid:1401366 |
| Quigley JD et al. | Effects of lasalocid on selected ruminal and blood metabolites in young calves. | 1992 | J. Dairy Sci. | pmid:1401374 |
| Tse CS and Williams DM | Inhibition of human endothelial cell proliferation in vitro in response to n-butyrate and propionate. | 1992 | J. Periodont. Res. | pmid:1403579 |
| MACRAE IC et al. | THE DECOMPOSITION OF 4-(2,4-DICHLOROPHENOXY) BUTYRIC ACID BY FLAVOBACTERIUM SP. | 1963 | J. Gen. Microbiol. | pmid:14045525 |
| ANNISON EF et al. | THE METABOLISM OF ACETIC ACID, PROPIONIC ACID AND BUTYRIC ACID IN SHEEP. | 1963 | Biochem. J. | pmid:14063864 |
| Lutter LC et al. | Effects of histone acetylation on chromatin topology in vivo. | 1992 | Mol. Cell. Biol. | pmid:1406675 |
| Chiofalo V et al. | Influence of the method of forage conservation on feeding behaviour, intake and characteristics of reticulo-rumen content, in sheep fed ad libitum. | 1992 | Reprod. Nutr. Dev. | pmid:1418399 |
| MATSUZAKI M et al. | PARADOXICAL PHASE OF SLEEP: ITS ARTIFICIAL INDUCTION IN THE CAT BY SODIUM BUTYRATE. | 1964 | Science | pmid:14207466 |
| Johnson JA | L-carnitine for treatment of distal ulcerative colitis. | 1992 | Gastroenterology | pmid:1426898 |
| Ogawa K et al. | Volatile fatty acids, lactic acid, and pH in the stools of breast-fed and bottle-fed infants. | 1992 | J. Pediatr. Gastroenterol. Nutr. | pmid:1432461 |
| Nachtigal MW et al. | Chorionic gonadotrophin and c-myc expression in growing and growth-inhibited (intermediate) trophoblasts. | 1992 Jul-Aug | Placenta | pmid:1438085 |
| Roettger V et al. | Multiple acyl-coenzyme A dehydrogenation disorders (MAD) responsive to riboflavin: biochemical studies in fibroblasts. | 1992 | Prog. Clin. Biol. Res. | pmid:1438377 |
| JOHNSON RB | The effect of the administration of acetic, propionic, and n-butyric acids upon the blood glucose and ketone body levels of goats. | 1955 | Cornell Vet | pmid:14390951 |
| IWAMA K and YAMAMOTO C | Locus of the action of gamma amino butyric acid in the suppression of muscular movements in cats. | 1959 | Tohoku J. Exp. Med. | pmid:14406170 |
| KITA T et al. | A possible metabolic pathway of gamma-guanido- and gamma-guanido-beta-oxy-butyric acid by heteroarginase. | 1961 | Jpn. J. Pharmacol. | pmid:14456496 |
| Tang DC and Taylor MW | Memory of butyrate induction by the Moloney murine sarcoma virus enhancer-promoter element. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1449468 |
| Wilson AJ et al. | TR3/Nur77 in colon cancer cell apoptosis. | 2003 | Cancer Res. | pmid:14500374 |
| Kurita-Ochiai T et al. | Cellular events involved in butyric acid-induced T cell apoptosis. | 2003 | J. Immunol. | pmid:14500654 |
| Karolewski BA et al. | Comparison of transfection conditions for a lentivirus vector produced in large volumes. | 2003 | Hum. Gene Ther. | pmid:14503964 |
| Li B et al. | Expression of butyrate response factor 1 in HTLV-1-transformed cells and its transactivation by tax protein. | 2003 | Arch. Virol. | pmid:14505090 |
| RodrÃguez-Cabezas ME et al. | Intestinal anti-inflammatory activity of dietary fiber (Plantago ovata seeds) in HLA-B27 transgenic rats. | 2003 | Clin Nutr | pmid:14512034 |
| Klampfer L et al. | Inhibition of interferon gamma signaling by the short chain fatty acid butyrate. | 2003 | Mol. Cancer Res. | pmid:14517348 |
| Estival A et al. | Decreased expression of transforming growth factor alpha during differentiation of human pancreatic cancer cells. | 1992 | Gastroenterology | pmid:1451978 |
| Vogt JA and Wolever TM | Fecal acetate is inversely related to acetate absorption from the human rectum and distal colon. | 2003 | J. Nutr. | pmid:14519799 |
| Um SJ et al. | Potent cytotoxic effects of novel retinamide derivatives in ovarian cancer cells. | 2003 | Biol. Pharm. Bull. | pmid:14519946 |
| Smartt HJ et al. | Increased NF-kappaB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cells. | 2003 | Br. J. Cancer | pmid:14520472 |
| Akah PA et al. | Evaluation of the anti-asthmatic property of Asystasia gangetica leaf extracts. | 2003 | J Ethnopharmacol | pmid:14522429 |
| Kyrylenko S et al. | Differential regulation of the Sir2 histone deacetylase gene family by inhibitors of class I and II histone deacetylases. | 2003 | Cell. Mol. Life Sci. | pmid:14523559 |
| Alrefai WA et al. | Regulation of butyrate uptake in Caco-2 cells by phorbol 12-myristate 13-acetate. | 2004 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:14525727 |
| Lingaas F and Tveit B | Etiology of acetonemia in Norwegian cattle. 2. Effect of butyric acid, valeric acid, and putrescine. | 1992 | J. Dairy Sci. | pmid:1452847 |
| Sklan D et al. | Fatty acids, calcium soaps of fatty acids, and cottonseeds fed to high yielding cows. | 1992 | J. Dairy Sci. | pmid:1452851 |
| Tung RS et al. | In vitro effects of the thiopeptide A10255 on ruminal fermentation and microbial populations. | 1992 | J. Dairy Sci. | pmid:1452854 |
| Zhang T et al. | Biohydrogen production from starch in wastewater under thermophilic condition. | 2003 | J. Environ. Manage. | pmid:14550657 |
| Smiricky-Tjardes MR et al. | Dietary galactooligosaccharides affect ileal and total-tract nutrient digestibility, ileal and fecal bacterial concentrations, and ileal fermentative characteristics of growing pigs. | 2003 | J. Anim. Sci. | pmid:14552381 |
| López S et al. | Effects of volatile fatty acid supply on their absorption and on water kinetics in the rumen of sheep sustained by intragastric infusions. | 2003 | J. Anim. Sci. | pmid:14552390 |
| Lu F et al. | Chromatin remodeling of the Kaposi's sarcoma-associated herpesvirus ORF50 promoter correlates with reactivation from latency. | 2003 | J. Virol. | pmid:14557628 |
| Pott I et al. | Detection of unusual carotenoid esters in fresh mango (Mangifera indica L. cv. 'Kent'). | 2003 | Phytochemistry | pmid:14559275 |
| Heerdt BG et al. | The intrinsic mitochondrial membrane potential (Deltapsim) is associated with steady-state mitochondrial activity and the extent to which colonic epithelial cells undergo butyrate-mediated growth arrest and apoptosis. | 2003 | Cancer Res. | pmid:14559818 |
| Lee IS and Nishikawa A | Polyozellus multiplex, a Korean wild mushroom, as a potent chemopreventive agent against stomach cancer. | 2003 | Life Sci. | pmid:14561527 |
| Ferrante RJ et al. | Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice. | 2003 | J. Neurosci. | pmid:14561870 |
| Liu XM et al. | Unique induction of p21(WAF1/CIP1)expression by vinorelbine in androgen-independent prostate cancer cells. | 2003 | Br. J. Cancer | pmid:14562033 |
| Jenkinson S et al. | Development of a novel high-throughput surrogate assay to measure HIV envelope/CCR5/CD4-mediated viral/cell fusion using BacMam baculovirus technology. | 2003 | J Biomol Screen | pmid:14567799 |
| Young SP et al. | A comparison of in vitro acylcarnitine profiling methods for the diagnosis of classical and variant short chain acyl-CoA dehydrogenase deficiency. | 2003 | Clin. Chim. Acta | pmid:14568186 |
| Mariani MR et al. | Correlation between butyrate-induced histone hyperacetylation turn-over and c-myc expression. | 2003 | J. Steroid Biochem. Mol. Biol. | pmid:14568568 |
| Ji XJ et al. | Effect of fetal hemoglobin-stimulating medicines on the interaction of DNA and protein of important erythroid regulatory elements. | 2003 | Biochem. Cell Biol. | pmid:14569302 |
| VanGulck JF et al. | Predicting biogeochemical calcium precipitation in landfill leachate collection systems. | 2003 | Biodegradation | pmid:14571950 |
| Mann KK et al. | A retinoid/butyric acid prodrug overcomes retinoic acid resistance in leukemias by induction of apoptosis. | 2003 | Mol. Cancer Res. | pmid:14573791 |
| Hrynevych IuP et al. | [Antioxidant properties of rhenium cluster complexes with butyric acid derivatives in blood plasma and erythrocytes]. | 2003 Jan-Feb | Ukr Biokhim Zh (1999) | pmid:14574740 |