butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Diverticulitis D004238 1 associated lipids
Salivary Gland Neoplasms D012468 1 associated lipids
Astigmatism D001251 1 associated lipids
Anaplasia D000708 1 associated lipids
Trophoblastic Neoplasms D014328 1 associated lipids
Diverticulitis, Colonic D004239 1 associated lipids
Aphakia, Postcataract D001036 1 associated lipids
Diverticulosis, Colonic D043963 1 associated lipids
Facial Injuries D005151 1 associated lipids
Gastrinoma D015408 1 associated lipids
Myoepithelioma D009208 1 associated lipids
Proctitis D011349 1 associated lipids
Urea Cycle Disorders, Inborn D056806 2 associated lipids
Glycogen Storage Disease Type II D006009 2 associated lipids
Intestinal Neoplasms D007414 2 associated lipids
Hemorrhoids D006484 2 associated lipids
Lymphoma, AIDS-Related D016483 2 associated lipids
Sarcoma, Avian D001357 2 associated lipids
Dentin, Secondary D003809 2 associated lipids
Colorectal Neoplasms, Hereditary Nonpolyposis D003123 2 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

Download all related citations
Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Tsai MH et al. Effect of platelet activating factor and butyrate on the expression of interleukin-2 receptor alpha in nasopharyngeal carcinoma cells. 2001 Int. J. Oncol. pmid:11605008
Gandolfi R et al. Efficient and selective microbial esterification with dry mycelium of Rhizopus oryzae. 2001 J. Biotechnol. pmid:11604169
Combourieu B et al. Identification of new derivatives of sinigrin and glucotropaeolin produced by the human digestive microflora using 1H NMR spectroscopy analysis of in vitro incubations. 2001 Drug Metab. Dispos. pmid:11602519
Lee YJ et al. Effect of iron concentration on hydrogen fermentation. 2001 Bioresour. Technol. pmid:11601547
Takahashi A et al. Chloride secretion induced by thermostable direct haemolysin of Vibrio parahaemolyticus depends on colonic cell maturation. 2001 J. Med. Microbiol. pmid:11599736
Zhang WL et al. Induction of heat shock proteins and its effects on glial differentiation in rat C6 glioblastoma cells. 2001 Kobe J Med Sci pmid:11599126
Bernhard D et al. Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts. 2001 Cell Death Differ. pmid:11598799
Chen Z et al. Combination of all-trans retinoic acid with butyric acid and its prodrugs markedly enhancing differentiation of human acute promyelocytic leukemia NB4 cells. 1999 Chin. Med. J. pmid:11593538
Kim DY et al. Biosynthesis of polyhydroxyalkanoate copolyester containing cyclohexyl groups by Pseudomonas oleovorans. 2001 Int. J. Biol. Macromol. pmid:11589966
Cummins CL et al. Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate. 2001 Pharm. Res. pmid:11587480
Lee GS et al. Layer-by-layer assembly of zeolite crystals on glass with polyelectrolytes as ionic linkers. 2001 J. Am. Chem. Soc. pmid:11583538
Kristensen NB Rumen microbial sequestration of [2-(13)C]acetate in cattle. 2001 J. Anim. Sci. pmid:11583438
Shiau MY et al. Establishment of a consistent L929 bioassay system for TNF-alpha quantitation to evaluate the effect of lipopolysaccharide, phytomitogens and cytodifferentiation agents on cytotoxicity of TNF-alpha secreted by adherent human mononuclear cells. 2001 Mediators Inflamm. pmid:11577996
Rosignoli P et al. Protective activity of butyrate on hydrogen peroxide-induced DNA damage in isolated human colonocytes and HT29 tumour cells. 2001 Carcinogenesis pmid:11577008
Leng SL et al. Insulin-like growth factor-II renders LIM 2405 human colon cancer cells resistant to butyrate-induced apoptosis: a potential mechanism for colon cancer cell survival in vivo. 2001 Carcinogenesis pmid:11577001
Lührs H et al. Butyrate inhibits interleukin-1-mediated nuclear factor-kappa B activation in human epithelial cells. 2001 Dig. Dis. Sci. pmid:11575451
Yin L et al. Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity. 2001 J. Biol. Chem. pmid:11572859
Mohiuddin I et al. Significant augmentation of pro-apoptotic gene therapy by pharmacologic bcl-xl down-regulation in mesothelioma. 2001 Cancer Gene Ther. pmid:11571532
Martin C et al. Comparison of non-tracer and tracer methods for determination of volatile fatty acid production rate in the rumen of sheep fed on two levels of intake. 2001 Br. J. Nutr. pmid:11570985
Jung M Inhibitors of histone deacetylase as new anticancer agents. 2001 Curr. Med. Chem. pmid:11562279
Yu HQ and Fang HH Acidification of mid- and high-strength dairy wastewaters. 2001 Water Res. pmid:11561632
Ochiai K et al. Effects of augmented delivery of pyruvate on myocardial high-energy phosphate metabolism at high workstate. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11557577
Kiela PR et al. Regulation of the rat NHE3 gene promoter by sodium butyrate. 2001 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11557515
Lal S et al. Vagal afferent responses to fatty acids of different chain length in the rat. 2001 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11557510
Shimada N et al. Alterations of gene expression in endoderm differentiation of F9 teratocarcinoma cells. 2001 Mol. Reprod. Dev. pmid:11553914
Shin HS et al. Performance of UASB reactor treating leachate from acidogenic fermenter in the two-phase anaerobic digestion of food waste. 2001 Water Res. pmid:11547866
Khan MR et al. Antimicrobial activity of Lithocarpus celebicus. 2001 Fitoterapia pmid:11543975
Davido DJ et al. Butyrate and propionate downregulate ERK phosphorylation in HT-29 colon carcinoma cells prior to differentiation. 2001 Eur. J. Cancer Prev. pmid:11535873
Dongmo AB et al. Anti-inflammatory and analgesic properties of the stem bark extracts of Erythrophleum suaveolens (Caesalpiniaceae), Guillemin & Perrottet. 2001 J Ethnopharmacol pmid:11535356
Stehle HW et al. Short-chain carboxylic acids produced by gram-negative anaerobic bacteria can accelerate or delay polymorphonuclear leukocyte apoptosis in vitro. 2001 J. Periodontol. pmid:11525438
Benjamin D and Jost JP Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation. 2001 Nucleic Acids Res. pmid:11522830
Ren H et al. Short-chain fatty acids induce intestinal epithelial heat shock protein 25 expression in rats and IEC 18 cells. 2001 Gastroenterology pmid:11522747
Kitazono M et al. Enhanced adenovirus transgene expression in malignant cells treated with the histone deacetylase inhibitor FR901228. 2001 Cancer Res. pmid:11522619
Reinhardt D et al. Post-transcriptional effects of interleukin-3, interferon-gamma, erythropoietin and butyrate on in vitro hemoglobin chain synthesis in congenital hemolytic anemia. 2001 Haematologica pmid:11522534
Ugazio E et al. The effect of formulation and concentration of cholesteryl butyrate solid lipid nanospheres (SLN) on NIH-H460 cell proliferation. 2001 Eur J Pharm Biopharm pmid:11522486
Finzer P et al. Inhibitors of histone deacetylase arrest cell cycle and induce apoptosis in cervical carcinoma cells circumventing human papillomavirus oncogene expression. 2001 Oncogene pmid:11521189
Witt O et al. Tumor cell differentiation by butyrate and environmental stress. 2001 Cancer Lett. pmid:11520601
Kasuga T Effect of glutamate analogues on red-green opponent interaction in monkey electroretinograms. 2001 Exp. Eye Res. pmid:11520106
Chattopadhyay S et al. Purification and stabilization of 99mTc-d,l-HMPAO: role of organic extractants. 2001 Nucl. Med. Biol. pmid:11518658
Sherfi SA and Hamad SH Microbiological and biochemical studies on Gergoush fermentation. 2001 Int. J. Food Microbiol. pmid:11518434
Walker GE et al. Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: molecular mechanism involves an Sp1/Sp3 multiprotein complex. 2001 Endocrinology pmid:11517158
Shankaranarayanan P et al. Acetylation by histone acetyltransferase CREB-binding protein/p300 of STAT6 is required for transcriptional activation of the 15-lipoxygenase-1 gene. 2001 J. Biol. Chem. pmid:11509556
Jørgensen J and Mortensen PB Hydrogen sulfide and colonic epithelial metabolism: implications for ulcerative colitis. 2001 Dig. Dis. Sci. pmid:11508674
Ito N et al. Inhibitory effects of sodium butyrate on proliferation and invasiveness of human glioma cells. 2001 Neurosurgery pmid:11504120
Huang P et al. [Inhibition of the expression of Epstein-Barr virus antigens in vitro by Chinese medicine compound "Dongxia wan"]. 2000 Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi pmid:11503041
Nakhoul NL et al. Ammonium interaction with the epithelial sodium channel. 2001 Am. J. Physiol. Renal Physiol. pmid:11502598
Kleessen B et al. Oligofructose and long-chain inulin: influence on the gut microbial ecology of rats associated with a human faecal flora. 2001 Br. J. Nutr. pmid:11502244
Hernandez A et al. Butyrate sensitizes human colon cancer cells to TRAIL-mediated apoptosis. 2001 Surgery pmid:11490359
Clarke KO et al. Tributyrin, an oral butyrate analogue, induces apoptosis through the activation of caspase-3. 2001 Cancer Lett. pmid:11485828
Duquette RA and Wray S pH regulation and buffering power in gastric smooth muscle. 2001 Pflugers Arch. pmid:11484779
Williamson DH and Ellington EV Hydroxypyruvate as a gluconeogenic substrate in rat hepatocytes. 1975 Biochem. J. pmid:1147901
Iacomino G et al. Transcriptional response of a human colon adenocarcinoma cell line to sodium butyrate. 2001 Biochem. Biophys. Res. Commun. pmid:11478796
Derjuga A et al. Expression of p21Waf1/Cip1 and cyclin D1 is increased in butyrate-resistant HeLa cells. 2001 J. Biol. Chem. pmid:11477082
Pouteau E et al. Acetate, propionate and butyrate in plasma: determination of the concentration and isotopic enrichment by gas chromatography/mass spectrometry with positive chemical ionization. 2001 J Mass Spectrom pmid:11473403
Hull CD and Cribb BW Olfaction in the Queensland fruit fly, Bactrocera tryoni. I: Identification of olfactory receptor neuron types responding to environmental odors. 2001 J. Chem. Ecol. pmid:11471941
Besong S et al. Influence of supplemental chromium on concentrations of liver triglyceride, blood metabolites and rumen VFA profile in steers fed a moderately high fat diet. 2001 J. Dairy Sci. pmid:11467818
Zheng T et al. Agricultural exposure to carbamate pesticides and risk of non-Hodgkin lymphoma. 2001 J. Occup. Environ. Med. pmid:11464396
Marilley D et al. Calretinin and calretinin-22k increase resistance toward sodium butyrate-induced differentiation in CaCo-2 colon adenocarcinoma cells. 2001 Exp. Cell Res. pmid:11461122
Shearer J et al. Why is there an "inert" metal center in the active site of nitrile hydratase? Reactivity and ligand dissociation from a five-coordinate Co(III) nitrile hydratase model. 2001 J. Am. Chem. Soc. pmid:11456548
Herrmann AP et al. Degradation of natural polyphenols by methanogenic consortia enriched from digested municipal sludge. 2001 Water Res. pmid:11456154
Marianna P et al. Valproic acid, trichostatin and their combination with hemin preferentially enhance gamma-globin gene expression in human erythroid liquid cultures. 2001 Haematologica pmid:11454524
Guzev VS et al. [Effect of butyric acid on physiologic activity of carbohydrate-oxidizing rhodococci]. 2001 May-Jun Mikrobiologiia pmid:11450452
Jørgensen J and Mortensen PB Substrate utilization by intestinal mucosal tissue strips from patients with inflammatory bowel disease. 2001 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11447021
Dyer KD and Rosenberg HF Transcriptional regulation of galectin-10 (eosinophil Charcot-Leyden crystal protein): a GC box (-44 to -50) controls butyric acid induction of gene expression. 2001 Life Sci. pmid:11441910
Chaves N et al. Identification and effects of interaction phytotoxic compounds from exudate of Cistus ladanifer leaves. 2001 J. Chem. Ecol. pmid:11441449
Kanai M et al. TGF-alpha inhibits apoptosis of murine gastric pit cells through an NF-kappaB-dependent pathway. 2001 Gastroenterology pmid:11438494
Takahashi N and Sato T Preferential utilization of dipeptides by Porphyromonas gingivalis. 2001 J. Dent. Res. pmid:11437213
Borel C et al. Initial amplification of duck hepatitis B virus covalently closed circular DNA after in vitro infection of embryonic duck hepatocytes is increased by cell cycle progression. 2001 Hepatology pmid:11431748
Topping DL and Clifton PM Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides. 2001 Physiol. Rev. pmid:11427691
Mahyar-Roemer M and Roemer K p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents. 2001 Oncogene pmid:11423989
Della Ragione F et al. Genes modulated by histone acetylation as new effectors of butyrate activity. 2001 FEBS Lett. pmid:11423116
Hsi LC et al. Evaluation of the activity and localization of 15-lipoxygenase-1 after introduction into human colorectal carcinoma Caco-2 cells. 2001 Apr-May Prostaglandins Leukot. Essent. Fatty Acids pmid:11418015
Vessey DA and Kelley M Characterization of the reaction mechanism for the XL-I form of bovine liver xenobiotic/medium-chain fatty acid:CoA ligase. 2001 Biochem. J. pmid:11415461
Nash MS et al. Enhanced inducible mGlu1alpha receptor expression in Chinese hamster ovary cells. 2001 J. Neurochem. pmid:11413250
Etchebehere C et al. Comamonas nitrativorans sp. nov., a novel denitrifier isolated from a denitrifying reactor treating landfill leachate. 2001 Int. J. Syst. Evol. Microbiol. pmid:11411724
Matthies C et al. Clostridium uliginosum sp. nov., a novel acid-tolerant, anaerobic bacterium with connecting filaments. 2001 Int. J. Syst. Evol. Microbiol. pmid:11411680
Karagül-Yüceer Y et al. Aroma-active components of nonfat dry milk. 2001 J. Agric. Food Chem. pmid:11409991
Long JP and Hughes JH Epstein-Barr virus latently infected cells are selectively deleted in simulated-microgravity cultures. 2001 In Vitro Cell. Dev. Biol. Anim. pmid:11409687
Rosato RR et al. Evidence of a functional role for the cyclin-dependent kinase-inhibitor p21WAF1/CIP1/MDA6 in promoting differentiation and preventing mitochondrial dysfunction and apoptosis induced by sodium butyrate in human myelomonocytic leukemia cells (U937). 2001 Int. J. Oncol. pmid:11408941
Wächtershäuser A et al. HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2. 2001 Carcinogenesis pmid:11408350
Rubin VN et al. Identification of new triarylethylene oxyalkanoic acid analogues as bone selective estrogen mimetics. 2001 Bioorg. Med. Chem. pmid:11408177
Méhul B et al. Calmodulin-like skin protein: a new marker of keratinocyte differentiation. 2001 J. Invest. Dermatol. pmid:11407979
Carman RJ and Woodburn MA Effects of low levels of ciprofloxacin on a chemostat model of the human colonic microflora. 2001 Regul. Toxicol. Pharmacol. pmid:11407931
Chan LM et al. A novel human suspension culture packaging cell line for production of high-titre retroviral vectors. 2001 Gene Ther. pmid:11406764
Vanecková I et al. Intracellular pH regulation in colonocytes of rat proximal colon. 2001 Biochim. Biophys. Acta pmid:11406345
Setlow JK et al. Evidence for gene silencing in Haemophilus influenzae. 2001 Mutat. Res. pmid:11406170
Noble R et al. Olfactory response to mushroom composting emissions as a function of chemical concentration. J. Environ. Qual. pmid:11401265
Ahring BK et al. Effect of temperature increase from 55 to 65 degrees C on performance and microbial population dynamics of an anaerobic reactor treating cattle manure. 2001 Water Res. pmid:11394779
Miyake H et al. Overexpression of Bcl-2 regulates sodium butyrate- and/or docetaxel-induced apoptosis in human bladder cancer cells both in vitro and in vivo. 2001 Int. J. Cancer pmid:11391617
Videla S et al. Dietary inulin improves distal colitis induced by dextran sodium sulfate in the rat. 2001 Am. J. Gastroenterol. pmid:11374687
Lopez-Avalos MD et al. Enhanced maturation of porcine neonatal pancreatic cell clusters with growth factors fails to improve transplantation outcome. 2001 Transplantation pmid:11374418
Archer SY et al. p21 gene regulation during enterocyte differentiation. 2001 J. Surg. Res. pmid:11368530
Hung MW et al. Differential regulation of placental and germ cell alkaline phosphatases by glucocorticoid and sodium butyrate in human gastric carcinoma cell line TMK-1. 2001 Arch. Biochem. Biophys. pmid:11361139
Greenberg VL et al. Histone deacetylase inhibitors promote apoptosis and differential cell cycle arrest in anaplastic thyroid cancer cells. 2001 Thyroid pmid:11349829
Lens PN et al. Effect of the liquid upflow velocity on thermophilic sulphate reduction in acidifying granular sludge reactors. 2001 Environ Technol pmid:11349377
Young RC and Zhang P The mechanism of propagation of intracellular calcium waves in cultured human uterine myocytes. 2001 Am. J. Obstet. Gynecol. pmid:11349193
Gaskin DJ et al. Alteration of lipase chain length specificity in the hydrolysis of esters by random mutagenesis. 2001 Biotechnol. Bioeng. pmid:11344447
Boosalis MS et al. Short-chain fatty acid derivatives stimulate cell proliferation and induce STAT-5 activation. 2001 Blood pmid:11342457
Itoh N et al. Cloning and biochemical characterization of Co(2+)-activated bromoperoxidase-esterase (perhydrolase) from Pseudomonas putida IF-3 strain. 2001 Biochim. Biophys. Acta pmid:11342031
Vincan E et al. Sodium butyrate-induced differentiation of human LIM2537 colon cancer cells decreases GSK-3beta activity and increases levels of both membrane-bound and Apc/axin/GSK-3beta complex-associated pools of beta-catenin. 2000 Oncol. Res. pmid:11341469