butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jeng JH et al. | Toxic and metabolic effect of sodium butyrate on SAS tongue cancer cells: role of cell cycle deregulation and redox changes. | 2006 | Toxicology | pmid:16737765 |
Thomas DJ et al. | Effect of sodium butyrate on metallothionein induction and cadmium cytotoxicity in ROS 17/2.8 cells. | 1991 | Toxicology | pmid:1996466 |
Ridd K et al. | Foetal rat lung epithelial (FRLE) cells: alterations in cellular homeostasis and gene expression in response to etoposide, hydrogen peroxide and sodium butyrate. | 2004 | Toxicology | pmid:14751676 |
Peleran JC et al. | Identification of the cooked food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and its N-acetylated and 3-N-demethylated metabolites in rat urine. | 1987 | Toxicology | pmid:3810661 |
Morris JB and Hubbs AF | Inhalation dosimetry of diacetyl and butyric acid, two components of butter flavoring vapors. | 2009 | Toxicol. Sci. | pmid:18940962 |
Krig SR and Rice RH | TCDD suppression of tissue transglutaminase stimulation by retinoids in malignant human keratinocytes. | 2000 | Toxicol. Sci. | pmid:10910994 |
Jergil M et al. | Short-time gene expression response to valproic acid and valproic acid analogs in mouse embryonic stem cells. | 2011 | Toxicol. Sci. | pmid:21427059 |
Di Renzo F et al. | Relationship between embryonic histonic hyperacetylation and axial skeletal defects in mouse exposed to the three HDAC inhibitors apicidin, MS-275, and sodium butyrate. | 2007 | Toxicol. Sci. | pmid:17517827 |
Knoll N et al. | Genotoxicity of 4-hydroxy-2-nonenal in human colon tumor cells is associated with cellular levels of glutathione and the modulation of glutathione S-transferase A4 expression by butyrate. | 2005 | Toxicol. Sci. | pmid:15829614 |
Teeguarden JG et al. | Derivation of a human equivalent concentration for n-butanol using a physiologically based pharmacokinetic model for n-butyl acetate and metabolites n-butanol and n-butyric acid. | 2005 | Toxicol. Sci. | pmid:15703268 |