butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Tirandaz H and Mohammadi E | Efficient tumor targeting by anaerobic butyrate-producing bacteria. | 2013 | Med. Hypotheses | pmid:23410499 |
Cuadrado-Tejedor M et al. | Phenylbutyrate is a multifaceted drug that exerts neuroprotective effects and reverses the Alzheimer´s disease-like phenotype of a commonly used mouse model. | 2013 | Curr. Pharm. Des. | pmid:23448463 |
Raybuck JD et al. | The histone deacetylase inhibitor sodium butyrate modulates acquisition and extinction of cocaine-induced conditioned place preference. | 2013 | Pharmacol. Biochem. Behav. | pmid:23454534 |
Wang HG et al. | Anticancer effects of sodium butyrate on hepatocellular carcinoma cells in vitro. | 2013 | Int. J. Mol. Med. | pmid:23440283 |
Kedia G et al. | Addressing the challenge of optimum polyhydroxyalkanoate harvesting: monitoring real time process kinetics and biopolymer accumulation using dielectric spectroscopy. | 2013 | Bioresour. Technol. | pmid:23500571 |
Fialova B et al. | Effect of histone deacetylase and DNA methyltransferase inhibitors on the expression of the androgen receptor gene in androgen-independent prostate cancer cell lines. | 2013 | Oncol. Rep. | pmid:23503510 |
Ayers LW et al. | Freezing to the predator odor 2,4,5 dihydro 2,5 trimethylthiazoline (TMT) is disrupted by olfactory bulb removal but not trigeminal deafferentation. | 2013 | Behav. Brain Res. | pmid:23831303 |
Liang X et al. | Sodium butyrate protects against severe burn-induced remote acute lung injury in rats. | 2013 | PLoS ONE | pmid:23874764 |
Wiese BI et al. | Short communication: Interrelationship between butyrate and glucose supply on butyrate and glucose oxidation by ruminal epithelial preparations. | 2013 | J. Dairy Sci. | pmid:23810600 |
Lim JH et al. | Refactoring redox cofactor regeneration for high-yield biocatalysis of glucose to butyric acid in Escherichia coli. | 2013 | Bioresour. Technol. | pmid:23127832 |
Zhang Z and Wu WS | Sodium butyrate promotes generation of human induced pluripotent stem cells through induction of the miR302/367 cluster. | 2013 | Stem Cells Dev. | pmid:23534850 |
Coskun T et al. | Carbodeoxygenation of biomass: the carbonylation of glycerol and higher polyols to monocarboxylic acids. | 2013 | Chemistry | pmid:23536394 |
Ximenes JC et al. | Valproic acid: an anticonvulsant drug with potent antinociceptive and anti-inflammatory properties. | 2013 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:23584602 |
Stojcev Z et al. | Early treatment and prevention of the radiation proctitis--composite enemas containing sodium butyrate. | 2013 | Int J Colorectal Dis | pmid:23516076 |
Nör C et al. | The histone deacetylase inhibitor sodium butyrate promotes cell death and differentiation and reduces neurosphere formation in human medulloblastoma cells. | 2013 | Mol. Neurobiol. | pmid:23516101 |
Venkataramanan KP et al. | The Clostridium small RNome that responds to stress: the paradigm and importance of toxic metabolite stress in C. acetobutylicum. | 2013 | BMC Genomics | pmid:24299206 |
Grousseau E et al. | Impact of sustaining a controlled residual growth on polyhydroxybutyrate yield and production kinetics in Cupriavidus necator. | 2013 | Bioresour. Technol. | pmid:24035890 |
Cuervo A et al. | Fiber from a regular diet is directly associated with fecal short-chain fatty acid concentrations in the elderly. | 2013 | Nutr Res | pmid:24074739 |
Dükkancı M and Gündüz G | Sonolytic degradation of butyric acid in aqueous solutions. | 2013 | J. Environ. Manage. | pmid:24029459 |
Sánchez-Tena S et al. | Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1. | 2013 | Biochim. Biophys. Acta | pmid:23994611 |
Damiani R et al. | Enhancement of human thyrotropin synthesis by sodium butyrate addition to serum-free CHO cell culture. | 2013 | Appl. Biochem. Biotechnol. | pmid:23996121 |
Mattace Raso G et al. | Effects of sodium butyrate and its synthetic amide derivative on liver inflammation and glucose tolerance in an animal model of steatosis induced by high fat diet. | 2013 | PLoS ONE | pmid:23861927 |
Zhang L et al. | Genome-wide screening for genes associated with valproic acid sensitivity in fission yeast. | 2013 | PLoS ONE | pmid:23861937 |
Misaghi S et al. | Resilient immortals, characterizing and utilizing Bax/Bak deficient Chinese hamster ovary (CHO) cells for high titer antibody production. | 2013 May-Jun | Biotechnol. Prog. | pmid:23596153 |
Tigunova EA et al. | [Alternative type of fuel--biobutanol]. | 2013 Nov-Dec | Tsitol. Genet. | pmid:24437198 |
Wu Z et al. | Histone deacetylase inhibitors suppress the growth of human osteosarcomas in vitro and in vivo. | 2013 Oct-Dec | J BUON | pmid:24344034 |
Molina S et al. | Antiproliferative effect of alkylglycerols as vehicles of butyric acid on colon cancer cells. | 2013 Oct-Nov | Chem. Phys. Lipids | pmid:23973778 |
Machiels K et al. | A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis. | 2014 | Gut | pmid:24021287 |
Liu J et al. | Sodium butyrate promotes the differentiation of rat bone marrow mesenchymal stem cells to smooth muscle cells through histone acetylation. | 2014 | PLoS ONE | pmid:25548915 |
Vicente F et al. | Subclinical ketosis on dairy cows in transition period in farms with contrasting butyric acid contents in silages. | 2014 | ScientificWorldJournal | pmid:25525616 |
Brocato J et al. | Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression. | 2014 | J. Biol. Chem. | pmid:25266719 |
Kondo Y et al. | Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells. | 2014 | PLoS ONE | pmid:25084468 |
Miltko R et al. | Can fungal zoospores be the source of energy for the rumen protozoa Eudiplodinium maggii? | 2014 | Anaerobe | pmid:24012688 |
Nankova BB et al. | Enteric bacterial metabolites propionic and butyric acid modulate gene expression, including CREB-dependent catecholaminergic neurotransmission, in PC12 cells--possible relevance to autism spectrum disorders. | 2014 | PLoS ONE | pmid:25170769 |
Bilgraer R et al. | A new approach combining LC-MS and multivariate statistical analysis for revealing changes in histone modification levels. | 2014 | Mol Biosyst | pmid:25167371 |
Xu G et al. | SAHA regulates histone acetylation, Butyrylation, and protein expression in neuroblastoma. | 2014 | J. Proteome Res. | pmid:25160476 |
Khan S and Jena G | Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-β1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats. | 2014 | Food Chem. Toxicol. | pmid:25158305 |
Moeinian M et al. | Beneficial effect of butyrate, Lactobacillus casei and L-carnitine combination in preference to each in experimental colitis. | 2014 | World J. Gastroenterol. | pmid:25152589 |
Tiwari P and Gupta KP | Modulation of miR-203 and its regulators as a function of time during the development of 7, 12 dimethylbenz [a] anthracene induced mouse skin tumors in presence or absence of the antitumor agents. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24792773 |
Castellano JF et al. | Reassessing the effects of histone deacetylase inhibitors on hippocampal memory and cognitive aging. | 2014 | Hippocampus | pmid:24753063 |
Zhou X et al. | Comparison of the effects of high energy carbon heavy ion irradiation and Eucommia ulmoides Oliv. on biosynthesis butyric acid efficiency in Clostridium tyrobutyricum. | 2014 | Bioresour. Technol. | pmid:24704888 |
Jang YS et al. | Metabolic engineering of Clostridium acetobutylicum for butyric acid production with high butyric acid selectivity. | 2014 | Metab. Eng. | pmid:24704310 |
Syngiridis K et al. | Favouring butyrate production for a new generation biofuel by acidogenic glucose fermentation using cells immobilised on γ-alumina. | 2014 | Bioresour. Technol. | pmid:24690582 |
Sarkar A et al. | Hippocampal HDAC4 contributes to postnatal fluoxetine-evoked depression-like behavior. | 2014 | Neuropsychopharmacology | pmid:24663010 |
Csikó G et al. | Effects of dietary sodium butyrate on hepatic biotransformation and pharmacokinetics of erythromycin in chickens. | 2014 | J. Vet. Pharmacol. Ther. | pmid:24628435 |
Kumar P et al. | All-trans retinoic acid and sodium butyrate enhance natriuretic peptide receptor a gene transcription: role of histone modification. | 2014 | Mol. Pharmacol. | pmid:24714214 |
Dos Santos MP et al. | In vitro antitumor effect of sodium butyrate and zoledronic acid combined with traditional chemotherapeutic drugs: a paradigm of synergistic molecular targeting in the treatment of Ewing sarcoma. | 2014 | Oncol. Rep. | pmid:24316794 |
Lee SM et al. | Digital mRNA profiling of N-glycosylation gene expression in recombinant Chinese hamster ovary cells treated with sodium butyrate. | 2014 | J. Biotechnol. | pmid:24333461 |
Dostal A et al. | Iron supplementation promotes gut microbiota metabolic activity but not colitis markers in human gut microbiota-associated rats. | 2014 | Br. J. Nutr. | pmid:24555487 |
Dengler F et al. | Bicarbonate-dependent transport of acetate and butyrate across the basolateral membrane of sheep rumen epithelium. | 2014 | Acta Physiol (Oxf) | pmid:23927569 |