butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kotantaki P and Mosialos G | The expression of tumor suppressor gene Cyld is upregulated by histone deacetylace inhibitors in human hepatocellular carcinoma cell lines. | 2016 | Cell Biochem. Funct. | pmid:27570065 |
Ãvila M et al. | Application of high pressure processing for controlling Clostridium tyrobutyricum and late blowing defect on semi-hard cheese. | 2016 | Food Microbiol. | pmid:27554159 |
Liang B and Fang J | Postnatal Isoflurane Exposure Induces Cognitive Impairment and Abnormal Histone Acetylation of Glutamatergic Systems in the Hippocampus of Adolescent Rats. | 2016 | J. Mol. Neurosci. | pmid:27307148 |
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Carretta MD et al. | Butyric acid stimulates bovine neutrophil functions and potentiates the effect of platelet activating factor. | 2016 | Vet. Immunol. Immunopathol. | pmid:27288853 |
Rephaeli A et al. | Bi-functional prodrugs of 5-aminolevulinic acid and butyric acid increase erythropoiesis in anemic mice in an erythropoietin-independent manner. | 2016 | Eur J Pharm Sci | pmid:27283485 |
Moreno FS et al. | Nutritional Epigenetics and the Prevention of Hepatocellular Carcinoma with Bioactive Food Constituents. | 2016 | Nutr Cancer | pmid:27266713 |
Aguilar EC et al. | Oral butyrate reduces oxidative stress in atherosclerotic lesion sites by a mechanism involving NADPH oxidase down-regulation in endothelial cells. | 2016 | J. Nutr. Biochem. | pmid:27261536 |
Zeng J et al. | Autophagy regulates biliary differentiation of hepatic progenitor cells through Notch1 signaling pathway. | 2016 | Cell Cycle | pmid:27259983 |
Zounr RA et al. | Improved Gas Chromatographic Determination of Guanidino Compounds Using Isovaleroylacetone and Ethyl Chloroformate as Derivatizing Reagents. | 2016 | Anal Sci | pmid:26860556 |
Wang J et al. | Therapeutic Effect of Histone Deacetylase Inhibitor, Sodium Butyrate, on Allergic Rhinitis In Vivo. | 2016 | DNA Cell Biol. | pmid:26859163 |
Ziegler K et al. | Butyric acid increases transepithelial transport of ferulic acid through upregulation of the monocarboxylate transporters SLC16A1 (MCT1) and SLC16A3 (MCT4). | 2016 | Arch. Biochem. Biophys. | pmid:26854723 |
Tao Y et al. | Production of Butyrate from Lactate by a Newly Isolated Clostridium sp. BPY5. | 2016 | Appl. Biochem. Biotechnol. | pmid:26842597 |
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Sayed M et al. | Selective oxidation of trimethylolpropane to 2,2-bis(hydroxymethyl)butyric acid using growing cells of Corynebacterium sp. ATCC 21245. | 2016 | J. Biotechnol. | pmid:26804932 |
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Curren J et al. | Identification and quantification of nuisance odors at a trash transfer station. | 2016 | Waste Manag | pmid:27692531 |
Silva FT et al. | Replacement of sugars to hydrogen production by Rhodobacter capsulatus using dark fermentation effluent as substrate. | 2016 | Bioresour. Technol. | pmid:26476167 |
Cueno ME and Ochiai K | Re-discovering periodontal butyric acid: New insights on an old metabolite. | 2016 | Microb. Pathog. | pmid:26466516 |
Han M et al. | Dietary grape seed proanthocyanidins (GSPs) improve weaned intestinal microbiota and mucosal barrier using a piglet model. | 2016 | Oncotarget | pmid:27880936 |
Rumpagaporn P et al. | Elevated propionate and butyrate in fecal ferments of hydrolysates generated by oxalic acid treatment of corn bran arabinoxylan. | 2016 | Food Funct | pmid:27841429 |
Karthikeyan OP et al. | Hydrolysis-acidogenesis of food waste in solid-liquid-separating continuous stirred tank reactor (SLS-CSTR) for volatile organic acid production. | 2016 | Bioresour. Technol. | pmid:26512860 |
Youn YS et al. | Molecular tuning of amino acids to form two-dimensional molecular networks driven by conformational preorganization. | 2016 | Chem. Commun. (Camb.) | pmid:27858018 |
Liu Y et al. | Dietary resistant starch type 4-derived butyrate attenuates nuclear factor-kappa-B1 through modulation of histone H3 trimethylation at lysine 27. | 2016 | Food Funct | pmid:27713965 |
Khan S and Jena G | Sodium butyrate reduces insulin-resistance, fat accumulation and dyslipidemia in type-2 diabetic rat: A comparative study with metformin. | 2016 | Chem. Biol. Interact. | pmid:27270450 |
Zhang Z et al. | O-Linked N-Acetylglucosamine (O-GlcNAc) Transferase and O-GlcNAcase Interact with Mi2β Protein at the Aγ-Globin Promoter. | 2016 | J. Biol. Chem. | pmid:27231347 |
Grimaldi R et al. | Fermentation properties and potential prebiotic activity of Bimuno® galacto-oligosaccharide (65 % galacto-oligosaccharide content) on in vitro gut microbiota parameters. | 2016 | Br. J. Nutr. | pmid:27267934 |
Kulcsár A et al. | Effects of butyrate on the insulin homeostasis of chickens kept on maize- or wheat-based diets. | 2016 | Acta Vet. Hung. | pmid:27993103 |
Miao W et al. | Sodium Butyrate Promotes Reassembly of Tight Junctions in Caco-2 Monolayers Involving Inhibition of MLCK/MLC2 Pathway and Phosphorylation of PKCβ2. | 2016 | Int J Mol Sci | pmid:27735862 |
Ain QU et al. | Analysis of Differential Efficacy and Affinity of GABA (α1/α2) Selective Modulators. | 2016 | Mol. Pharm. | pmid:27704838 |
Sun H et al. | Effects of addition of Aspergillus oryzae culture and 2-hydroxyl-4-(methylthio) butanoic acid on milk performance and rumen fermentation of dairy cows. | 2017 | Anim. Sci. J. | pmid:27506446 |
Gulfam A et al. | Characteristics of lactic acid bacteria isolates and their effect on the fermentation quality of Napier grass silage at three high temperatures. | 2017 | J. Sci. Food Agric. | pmid:27539868 |
Hrgovic I et al. | Histone deacetylase inhibitors interfere with angiogenesis by decreasing endothelial VEGFR-2 protein half-life in part via a VE-cadherin-dependent mechanism. | 2017 | Exp. Dermatol. | pmid:27487811 |
Anantharaju PG et al. | Induction of colon and cervical cancer cell death by cinnamic acid derivatives is mediated through the inhibition of Histone Deacetylases (HDAC). | 2017 | PLoS ONE | pmid:29190639 |
Seifrtová M et al. | Haemanthamine alters sodium butyrate-induced histone acetylation, p21 expression, Chk1 and Chk2 activation and leads to increased growth inhibition and death in A2780 ovarian cancer cells. | 2017 | Phytomedicine | pmid:28991639 |
Sałkowska A et al. | Differentiation stage-specific effect of histone deacetylase inhibitors on the expression of RORγT in human lymphocytes. | 2017 | J. Leukoc. Biol. | pmid:28951421 |
Wu Q et al. | Tailoring the Oxidative Stress Tolerance of Clostridium tyrobutyricum CCTCC W428 by Introducing Trehalose Biosynthetic Capability. | 2017 | J. Agric. Food Chem. | pmid:28925260 |
Sanz M et al. | Namalides B and C and Spumigins K-N from the Cultured Freshwater Cyanobacterium Sphaerospermopsis torques-reginae. | 2017 | J. Nat. Prod. | pmid:28876933 |
Meenongyai W et al. | Effects of forage ensiling and ration fermentation on total mixed ration pH, ruminal fermentation and performance of growing Holstein-Zebu cross steers. | 2017 | Anim. Sci. J. | pmid:28370998 |
Zheng ML et al. | Dynamics of microbial community during ensiling direct-cut alfalfa with and without LAB inoculant and sugar. | 2017 | J. Appl. Microbiol. | pmid:28370869 |
Foote AP et al. | Effect of abomasal butyrate infusion on gene expression in the duodenum of lambs. | 2017 | J. Anim. Sci. | pmid:28380531 |
Paiva I et al. | Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage. | 2017 | Hum. Mol. Genet. | pmid:28369321 |
Lynch H et al. | Investigation of in-feed organic acids as a low cost strategy to combat Salmonella in grower pigs. | 2017 | Prev. Vet. Med. | pmid:28364832 |
Fu H et al. | Butyric acid production from lignocellulosic biomass hydrolysates by engineered Clostridium tyrobutyricum overexpressing xylose catabolism genes for glucose and xylose co-utilization. | 2017 | Bioresour. Technol. | pmid:28343058 |
Kim YH and Lee JK | Histone deacetylase inhibitors suppress immature dendritic cell's migration by regulating CC chemokine receptor 1 expression. | 2017 | Cell. Immunol. | pmid:28341057 |
Egawa G et al. | SCFAs Control Skin Immune Responses via Increasing Tregs. | 2017 | J. Invest. Dermatol. | pmid:28340682 |
Yan JK et al. | Sodium butyrate attenuates soybean oil-based lipid emulsion-induced increase in intestinal permeability of lipopolysaccharide by modulation of P-glycoprotein in Caco-2 cells. | 2017 | Biochem. Biophys. Res. Commun. | pmid:27888107 |
Schwarz A et al. | The Short-Chain Fatty Acid Sodium Butyrate Functions as a Regulator of the Skin Immune System. | 2017 | J. Invest. Dermatol. | pmid:27887954 |
Zhang C et al. | Differential effect of early antibiotic intervention on bacterial fermentation patterns and mucosal gene expression in the colon of pigs under diets with different protein levels. | 2017 | Appl. Microbiol. Biotechnol. | pmid:27913852 |