butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Xiong XR et al. | Sodium butyrate improves the cloned yak embryo viability and corrects gene expression patterns. | 2015 | Zygote | pmid:23759515 |
Peng Z et al. | Taxonomic study on Lathrobium Gravenhorst (Coleoptera, Staphylinidae, Paederinae) from Longwangshan Mountain, East China. | 2012 | Zookeys | pmid:22328854 |
Yin ZW et al. | On the Chinese species of the genus Intestinarius Kurbatov (Coleoptera, Staphylinidae, Pselaphinae). | 2011 | Zookeys | pmid:21998498 |
Vester BM et al. | Influence of feeding raw or extruded feline diets on nutrient digestibility and nitrogen metabolism of African wildcats (Felis lybica). | Zoo Biol. | pmid:20095004 | |
Vester BM et al. | Evaluation of nutrient digestibility and fecal characteristics of exotic felids fed horse- or beef-based diets: use of the domestic cat as a model for exotic felids. | Zoo Biol. | pmid:19830746 | |
Xi L et al. | [Changes in telomerase activity decreases in MCF-7 cells during apoptosis induced by sodium butyrate]. | 2005 | Zhonghua Zhong Liu Za Zhi | pmid:15771789 |
Kan YY et al. | Effects of polar organic compounds on gynecologic cancers. | 1988 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:3224317 |
Chang YF et al. | Effect of sodium butyrate on glucocorticoid-sensitive and -resistant P1798 lymphosarcoma. | 1992 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:1312378 |
Chang CC et al. | Effects of sodium butyrate on the secretion of beta-2-microglobulin and calcitonin in a human ovarian cancer cell line OC-3-VGH. | 1988 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:3066455 |
Cao Z et al. | [Induction of human cervical carcinoma by human papilloma virus and tumor promoters]. | 2002 | Zhonghua Yi Xue Za Zhi | pmid:12425820 |
Chen YX et al. | [Regulation of histone acetylation on the expression of cell cycle-associated genes in human colon cancer cell lines]. | 2004 | Zhonghua Yi Xue Za Zhi | pmid:15059516 |
Shen WJ et al. | [Effects of sodium butyrate on proliferation of human gastric cancer cells and expression of p16 gene]. | 2008 | Zhonghua Yi Xue Za Zhi | pmid:18844115 |
Li W et al. | [Up-regulation of costimulatory molecules by sodium butyrate in acute leukemia cells and its molecular mechanism]. | 2005 | Zhonghua Xue Ye Xue Za Zhi | pmid:15949284 |
Li W et al. | [The proteomics study of apoptotic NB4 cells induced by sodium butyrate]. | 2006 | Zhonghua Xue Ye Xue Za Zhi | pmid:17147243 |
Zhu P et al. | [Effect and mechanism of inhibition of lipopolysaccharide-induced pulmonary fibrosis by butyric acid]. | 2016 | Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | pmid:26805528 |
Zhang LT et al. | [The potential role of high mobility group-1 protein in the pathogenesis of sepsis-induced multiple organ dysfunction syndrome in rats]. | 2003 | Zhonghua Wai Ke Za Zhi | pmid:12882679 |
Huang P et al. | [Inhibition of the expression of Epstein-Barr virus antigens in vitro by Chinese medicine compound "Dongxia wan"]. | 2000 | Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi | pmid:11503041 |
Chiou JF et al. | Purification of Epstein-Barr virus associated DNase with affinity chromatography of nasopharyngeal carcinoma patient serum. | 1990 | Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi | pmid:2168313 |
Gong L et al. | [Effects of sodium butyrate on proliferation of human oral squamous carcinoma cell line and expression of p27Kip1]. | 2010 | Zhonghua Kou Qiang Yi Xue Za Zhi | pmid:21176600 |
Wang P et al. | [Sodium butyrate induces rat hepatic oval cells differentiating into mature hepatocytes in vitro]. | 2004 | Zhonghua Gan Zang Bing Za Zhi | pmid:15619336 |
Gao L et al. | [Effects of sodium butyrate on growth, apoptosis and telomerase activity in Hep-2 cells]. | 2007 | Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:17432359 |
Wang J et al. | [Experimental study of baculovirus-mediated transfection of spiral ganglion cells in rats]. | 2007 | Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:18335755 |
Shen Z et al. | [The promoter effects of sodium butyrate on the malignant transformation of the immortalized esophageal epithelium induced by human papillomavirus]. | 2002 | Zhonghua Bing Li Xue Za Zhi | pmid:12417090 |
Shen Z et al. | [The effects of sodium butyrate on proliferation, differentiation and apoptosis in immortalized esophageal epithelial cells]. | 2001 | Zhonghua Bing Li Xue Za Zhi | pmid:11866968 |
Bian XC et al. | [Effect of inhibitor of differentiation-1 on murine dendritic cell sarcoma cells]. | 2008 | Zhonghua Bing Li Xue Za Zhi | pmid:18956650 |
Wu S et al. | [Chemical constituents of Eupatorium lindleyanum]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:22792793 |
Li SY | [Expression of cellular oncogenes in human hepatocellular carcinoma cell line BEL 7402 and the effect of sodium butyrate on the expression of cellular oncogenes]. | 1990 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:1964112 |
Yao YM et al. | [Advances in high mobility group box-1 protein mediated multiple organ dysfunction and its potential interventional strategies]. | 2007 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:19209785 |
Chen YJ et al. | [MicroRNA differential expression profile during differentiation of embryonic stem cells towards hepatocytes induced by sodium butyrate]. | 2008 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:18795623 |
Tu C et al. | [Differentiation of human glioma cells BT-325 induced by sodium butyrate]. | 2000 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:12903431 |
Bin X et al. | Releasing effect of thymidine on G1 phase arrest of erythroleukemia cells caused by FUDR and HMBA. | 1984 | Zhongguo Yao Li Xue Bao | pmid:6235712 |
Huang JC et al. | [Protective effect of histone acetylation against cortical injury in neonatal rats]. | 2017 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:28100329 |
Wang Y et al. | [Analysis of plasma metabonomics of mini-swines with qi deficiency and blood stasis syndrome due to chronic myocardial ischemia]. | 2011 | Zhong Xi Yi Jie He Xue Bao | pmid:21288451 |
Deinhofer M and Weissenböck H | Diagnosis of diabetes mellitus in a bull by means of butyrate infusion. | 1998 | Zentralbl Veterinarmed A | pmid:9719760 |
Gálfi P et al. | Effect of sodium n-butyrate on primary ruminal epithelial cell culture. | 1981 | Zentralbl Veterinarmed A | pmid:6792837 |
Gálfi P et al. | Demonstration of keratinizing effect of n-butyrate on day-old chicken crop epithelium. | 1985 | Zentralbl Veterinarmed A | pmid:2581396 |
Gürtler H et al. | Acute metabolic and hormonal effects of intravenously administered sodium n-butyrate in untreated and alloxan-diabetic sheep. | 1993 | Zentralbl Veterinarmed A | pmid:8212952 |
Gálfi P et al. | Dissimilar ruminal epithelial response to short-term and continuous intraruminal infusion of sodium n-butyrate. | 1986 | Zentralbl Veterinarmed A | pmid:3085388 |
Andersson L and Lundström K | Effect of feeding silage with high butyric acid content on ketone body formation and milk yield in postparturient dairy cows. | 1985 | Zentralbl Veterinarmed A | pmid:3919514 |
Gálfi P et al. | Keratinization of cultured ruminal epithelial cells treated with butyrate and lactate. | 1983 | Zentralbl Veterinarmed A | pmid:6198824 |
Werner H et al. | [A new butyric acid-producing bacteroides species: B. splanchnicus n. sp. (author's transl)]. | 1975 | Zentralbl Bakteriol Orig A | pmid:168701 |
WALTER M | [Not Available]. | 1947 | Z Vitam Forsch | pmid:20296102 |
Ledl F et al. | [Demonstration and identification of a new Maillard compound in heated milk]. | 1986 | Z Lebensm Unters Forsch | pmid:3953158 |
Andrey D | A simple gas chromatography method for the determination of ethylcarbamate in spirits. | 1987 | Z Lebensm Unters Forsch | pmid:3617935 |
Scherz H | [The analysis of polysaccharides used as food additives. VIII. Simple qualitative and semiquantitative procedures for the determination of alginates in food]. | 1984 | Z Lebensm Unters Forsch | pmid:6485554 |
Idstein H et al. | [Volatile acids in tropical fruits: cherimoya (Annona cherimolia, Mill.), guava (psidium guajava, L.), mango (Mangifera indica, L., var. Alphonso), papaya (Carica papaya, L.)]. | 1985 | Z Lebensm Unters Forsch | pmid:4013523 |
Thiele A and Schwedt G | [Differential analysis of the binding forms of iron in various plant foodstuffs]. | 1985 | Z Lebensm Unters Forsch | pmid:3984516 |
Vömel T et al. | [Phagocytic activity of isolated perfused liver of rats of different ages. Biochemical and structural studies following perfusion with Cu-ceruloplasmin]. | 1984 Mar-Apr | Z Gerontol | pmid:6730634 |
Bender A et al. | Colonic fermentation as affected by antibiotics and acidic pH: Application of an in vitro model. | 2001 | Z Gastroenterol | pmid:11778150 |
Bartram HP et al. | Antagonistic effects of deoxycholic acid and butyrate on epithelial cell proliferation in the proximal and distal human colon. | 1994 | Z Gastroenterol | pmid:7975774 |
Pallauf J et al. | Influence of cAMP-effector-agonists on the synthesis of metallothionein in rat primary hepatocytes. | 1995 | Z Ernahrungswiss | pmid:8585245 |
Jacobasch G and Jacobasch KH | [Molecular etiology of colorectal carcinogenesis, clinical manifestations and therapy]. | 1997 | Z Arztl Fortbild Qualitatssich | pmid:9244653 |
Kast RE | Evidence that amphotericin B mediates reactivation of latent Epstein-Barr virus in Hodgkin's lymphoma allowing cytotoxicity by acyclovir. | 2006 | Yonsei Med. J. | pmid:16642564 |
Kaneko N et al. | [Susceptibility of spore-forming butyric acid bacteria to antimicrobial agents]. | 2012 | Yakugaku Zasshi | pmid:22790032 |
Ishihara K | [Role of eosinophils in allergic inflammation]. | 2005 | Yakugaku Zasshi | pmid:16141691 |
Oshikata A et al. | [Selective elimination of the transformed hepatic stem cells using hybrid liposomes]. | 2011 | Yakugaku Zasshi | pmid:21532272 |
Rogers KM and Barnsley EA | The metabolism of S-carboxyalkylcysteines in man. | 1977 | Xenobiotica | pmid:888445 |
Shi SL et al. | Effects of tachyplesin and n-sodium butyrate on proliferation and gene expression of human gastric adenocarcinoma cell line BGC-823. | 2006 | World J. Gastroenterol. | pmid:16586536 |
Chiang YW et al. | Efficient expression of histidine-tagged large hepatitis delta antigen in baculovirus-transduced baby hamster kidney cells. | 2006 | World J. Gastroenterol. | pmid:16570347 |
Yin HY et al. | Baculovirus vector-mediated transfer of NIS gene into colon tumor cells for radionuclide therapy. | 2010 | World J. Gastroenterol. | pmid:21072902 |
Zhang ZH et al. | Targeting cyclooxygenase-2 with sodium butyrate and NSAIDs on colorectal adenoma/carcinoma cells. | 2004 | World J. Gastroenterol. | pmid:15378772 |
Roda A et al. | A new oral formulation for the release of sodium butyrate in the ileo-cecal region and colon. | 2007 | World J. Gastroenterol. | pmid:17373743 |
Schneider SM et al. | Effects of Saccharomyces boulardii on fecal short-chain fatty acids and microflora in patients on long-term total enteral nutrition. | 2005 | World J. Gastroenterol. | pmid:16273644 |
Chen YX et al. | Histone acetylation regulates p21WAF1 expression in human colon cancer cell lines. | 2004 | World J. Gastroenterol. | pmid:15309711 |
Tedelind S et al. | Anti-inflammatory properties of the short-chain fatty acids acetate and propionate: a study with relevance to inflammatory bowel disease. | 2007 | World J. Gastroenterol. | pmid:17569118 |
He L et al. | Possible mechanism for the regulation of glucose on proliferation, inhibition and apoptosis of colon cancer cells induced by sodium butyrate. | 2007 | World J. Gastroenterol. | pmid:17663521 |
Canani RB et al. | Potential beneficial effects of butyrate in intestinal and extraintestinal diseases. | 2011 | World J. Gastroenterol. | pmid:21472114 |
Pacheco RG et al. | Use of butyrate or glutamine in enema solution reduces inflammation and fibrosis in experimental diversion colitis. | 2012 | World J. Gastroenterol. | pmid:22969190 |
Moeinian M et al. | Beneficial effect of butyrate, Lactobacillus casei and L-carnitine combination in preference to each in experimental colitis. | 2014 | World J. Gastroenterol. | pmid:25152589 |
Larauche M et al. | Stress-induced visceral analgesia assessed non-invasively in rats is enhanced by prebiotic diet. | 2012 | World J. Gastroenterol. | pmid:22294825 |
Yan J and Xu YH | Tributyrin inhibits human gastric cancer SGC-7901 cell growth by inducing apoptosis and DNA synthesis arrest. | 2003 | World J. Gastroenterol. | pmid:12679905 |
Kanauchi O et al. | Eubacterium limosum ameliorates experimental colitis and metabolite of microbe attenuates colonic inflammatory action with increase of mucosal integrity. | 2006 | World J. Gastroenterol. | pmid:16534848 |
Zhou D et al. | Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier. | 2017 | World J. Gastroenterol. | pmid:28104981 |
Zhang HQ et al. | Therapeutic effects of Clostridium butyricum on experimental colitis induced by oxazolone in rats. | 2009 | World J. Gastroenterol. | pmid:19370778 |
Schröder O et al. | Upregulation of 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase by butyrate in Caco-2 cells. | 2005 | World J. Gastroenterol. | pmid:16437660 |
Shivshankar P and Devi SC | Screening of stimulatory effects of dietary risk factors on mouse intestinal cell kinetics. | 2005 | World J. Gastroenterol. | pmid:15633224 |
Kobori A et al. | Butyrate stimulates IL-32alpha expression in human intestinal epithelial cell lines. | 2010 | World J. Gastroenterol. | pmid:20480520 |
Yamawaki Y et al. | Antidepressant-like effect of sodium butyrate (HDAC inhibitor) and its molecular mechanism of action in the rat hippocampus. | 2012 | World J. Biol. Psychiatry | pmid:21812623 |
Cho HJ et al. | The combination effect of sodium butyrate and 5-Aza-2'-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines. | 2009 | World J Surg Oncol | pmid:19460134 |
Chen Y et al. | In vitro and in vivo double-enhanced suicide gene therapy mediated by generation 5 polyamidoamine dendrimers for PC-3 cell line. | 2012 | World J Surg Oncol | pmid:22226139 |
Zhang L et al. | Histone deacetylase inhibitors attenuate acute lung injury during cecal ligation and puncture-induced polymicrobial sepsis. | 2010 | World J Surg | pmid:20177680 |
Lawrance IC | Novel topical therapies for distal colitis. | 2010 | World J Gastrointest Pharmacol Ther | pmid:21577301 |
O'Keefe SJ et al. | Effect of fiber supplementation on the microbiota in critically ill patients. | 2011 | World J Gastrointest Pathophysiol | pmid:22180847 |
Sanduja S et al. | The roles of TTP and BRF proteins in regulated mRNA decay. | Wiley Interdiscip Rev RNA | pmid:21278925 | |
Cheng G et al. | [Isolation and reassociation of acetogen and methanogen in a syntrophobic coculture degrading butyrate anaerobically]. | 1995 | Wei Sheng Wu Xue Bao | pmid:8745550 |
Fu B et al. | Control of C/N ratio for butyric acid production from textile wastewater sludge by anaerobic digestion. | 2012 | Water Sci. Technol. | pmid:22339023 |
Yu HQ and Fang HH | Acidification of mid- and high-strength dairy wastewaters. | 2001 | Water Res. | pmid:11561632 |
Ahring BK et al. | Effect of temperature increase from 55 to 65 degrees C on performance and microbial population dynamics of an anaerobic reactor treating cattle manure. | 2001 | Water Res. | pmid:11394779 |
Abreu AA et al. | Quantitative image analysis as a diagnostic tool for identifying structural changes during a revival process of anaerobic granular sludge. | 2007 | Water Res. | pmid:17316742 |
Jiang S et al. | Biological short-chain fatty acids (SCFAs) production from waste-activated sludge affected by surfactant. | 2007 | Water Res. | pmid:17499838 |
Brennan RA et al. | Chitin and corncobs as electron donor sources for the reductive dechlorination of tetrachloroethene. | 2006 | Water Res. | pmid:16725176 |
Briones AM et al. | Characterization of microbial trophic structures of two anaerobic bioreactors processing sulfate-rich waste streams. | 2009 | Water Res. | pmid:19643455 |
Baldwin DS and Mitchell A | Impact of sulfate pollution on anaerobic biogeochemical cycles in a wetland sediment. | 2012 | Water Res. | pmid:22204939 |
Stone JJ et al. | Effect of antimicrobial compounds tylosin and chlortetracycline during batch anaerobic swine manure digestion. | 2009 | Water Res. | pmid:19695662 |
Hidalgo MD and GarcÃa-Encina PA | Biofilm development and bed segregation in a methanogenic fluidized bed reactor. | 2002 | Water Res. | pmid:12171407 |
Li Z et al. | Effect of iron on the sensitivity of hydrogen, acetate, and butyrate metabolism to inhibition by long-chain fatty acids in vegetable-oil-enriched freshwater sediments. | 2005 | Water Res. | pmid:16000206 |
Herrmann AP et al. | Degradation of natural polyphenols by methanogenic consortia enriched from digested municipal sludge. | 2001 | Water Res. | pmid:11456154 |
DiStefano TD and Palomar A | Effect of anaerobic reactor process configuration on useful energy production. | 2010 | Water Res. | pmid:20181375 |
Zhao BH et al. | Modeling anaerobic digestion of aquatic plants by rumen cultures: cattail as an example. | 2009 | Water Res. | pmid:19297004 |
Azbar N et al. | Effect of process configuration and substrate complexity on the performance of anaerobic processes. | 2001 | Water Res. | pmid:11228981 |