ERIODICTYOL

Eriodictyol is a lipid of Polyketides (PK) class. Eriodictyol is associated with abnormalities such as Hyperostosis, Diffuse Idiopathic Skeletal, Macular degeneration, Consumption-archaic term for TB, Retinal Diseases and PARAGANGLIOMAS 4. The involved functions are known as glutathione biosynthetic process, Cytoprotection, Oxidants, protein expression and Cell Survival. Eriodictyol often locates in Cytoplasmic matrix, Protoplasm, Cytoplasmic, Cell Fraction and Back. The associated genes with Eriodictyol are NQO, HMOX1 gene, IMPACT gene, RPS6KA3 gene and GDNF gene.

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Introduction

To understand associated biological information of ERIODICTYOL, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ERIODICTYOL?

ERIODICTYOL is suspected in Macular degeneration, Retinal Diseases, PARAGANGLIOMAS 4 and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ERIODICTYOL

MeSH term MeSH ID Detail
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with ERIODICTYOL

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ERIODICTYOL?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with ERIODICTYOL?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with ERIODICTYOL?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with ERIODICTYOL?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ERIODICTYOL?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with ERIODICTYOL

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Authors Title Published Journal PubMed Link
Li H et al. R-eriodictyol and S-eriodictyol exhibited comparable effect against H2O2-induced oxidative stress in EA.hy926 cells. 2014 Drug Discov Ther pmid:25382557
Zhu S et al. Efficient synthesis of eriodictyol from L-tyrosine in Escherichia coli. 2014 Appl. Environ. Microbiol. pmid:24610848
Foresti R et al. Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells. 2013 Pharmacol. Res. pmid:23942037
Lee E et al. Binding model for eriodictyol to Jun-N terminal kinase and its anti-inflammatory signaling pathway. 2013 BMB Rep pmid:24195792
Park SJ et al. Effect of eriodictyol on the development of atopic dermatitis-like lesions in ICR mice. 2013 Biol. Pharm. Bull. pmid:23902981
Liu Q et al. Biosynthesis of homoeriodictyol from eriodictyol by flavone 3'-O-methyltransferase from recombinant Yarrowia lioplytica: Heterologous expression, biochemical characterization, and optimal transformation. 2013 J. Biotechnol. pmid:23906843
Jing X et al. Eriodictyol-7-O-glucoside activates Nrf2 and protects against cerebral ischemic injury. 2013 Toxicol. Appl. Pharmacol. pmid:24466583
Straub I et al. Citrus fruit and fabacea secondary metabolites potently and selectively block TRPM3. 2013 Br. J. Pharmacol. pmid:23190005
Hu YF and Wu CC [Chemical constituents from stems of Lonicera macranthoides]. 2012 Zhong Yao Cai pmid:22734414
Bucolo C et al. Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats. 2012 Biochem. Pharmacol. pmid:22484312