MeSH term | MeSH ID | Detail |
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Coronary Occlusion | D054059 | 4 associated lipids |
14,15-eet is a lipid of Fatty Acyls (FA) class. 14,15-eet is associated with abnormalities such as Heart failure, Chronic Obstructive Airway Disease, Pneumonia and Fatty Liver. The involved functions are known as chromophore, Stereochemistry, Cell Respiration, cell transformation and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. 14,15-eet often locates in Lambda, Cardiovascular system, Blood, Body tissue and Protoplasm. The associated genes with 14,15-eet are CCL2 gene, Cytokine Gene, CYP2C18 gene, CYP2C19 gene and TEK gene. The related lipids are Palmitates.
To understand associated biological information of 14,15-eet, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
14,15-eet is suspected in Heart failure, Chronic Obstructive Airway Disease, Pneumonia, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 14,15-eet
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Sporková A et al. | Vasodilatory responses of renal interlobular arteries to epoxyeicosatrienoic acids analog are not enhanced in Ren-2 transgenic hypertensive rats: evidence against a role of direct vascular effects of epoxyeicosatrienoic acids in progression of experimental heart failure. | 2017 | Physiol Res | pmid:27782740 |
Li Y et al. | 14,15-Epoxyeicosatrienoic acid suppresses cigarette smoke condensate-induced inflammation in lung epithelial cells by inhibiting autophagy. | 2016 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:27591243 |
El-Sikhry HE et al. | Novel Roles of Epoxyeicosanoids in Regulating Cardiac Mitochondria. | 2016 | PLoS ONE | pmid:27494529 |
Sporková A et al. | Interlobular Arteries From 2-Kidney, 1-Clip Goldblatt Hypertensive Rats' Exhibit-Impaired Vasodilator Response to Epoxyeicosatrienoic Acids. | 2016 | Am. J. Med. Sci. | pmid:27140711 |
Kandhi S et al. | EETs Elicit Direct Increases in Pulmonary Arterial Pressure in Mice. | 2016 | Am. J. Hypertens. | pmid:26304959 |
Yang L et al. | CYP epoxygenase 2J2 prevents cardiac fibrosis by suppression of transmission of pro-inflammation from cardiomyocytes to macrophages. | 2015 Jan-Mar | Prostaglandins Other Lipid Mediat. | pmid:25686540 |
Kandhi S et al. | EET-dependent potentiation of pulmonary arterial pressure: sex-different regulation of soluble epoxide hydrolase. | 2015 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:26498250 |
Li P et al. | Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. | 2015 | Nature | pmid:26201599 |
Jiang JX et al. | EETs Attenuate Ox-LDL-Induced LTB4 Production and Activity by Inhibiting p38 MAPK Phosphorylation and 5-LO/BLT1 Receptor Expression in Rat Pulmonary Arterial Endothelial Cells. | 2015 | PLoS ONE | pmid:26035589 |
Yu G et al. | 14,15-epoxyeicosatrienoic Acid suppresses cigarette smoke extract-induced apoptosis in lung epithelial cells by inhibiting endoplasmic reticulum stress. | 2015 | Cell. Physiol. Biochem. | pmid:25968975 |