| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Hyperemia | D006940 | 25 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Pre-Eclampsia | D011225 | 16 associated lipids |
| Hypertrophy | D006984 | 16 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Lung Injury | D055370 | 14 associated lipids |
14,15-eet
14,15-eet is a lipid of Fatty Acyls (FA) class. 14,15-eet is associated with abnormalities such as Heart failure, Chronic Obstructive Airway Disease, Pneumonia and Fatty Liver. The involved functions are known as chromophore, Stereochemistry, Cell Respiration, cell transformation and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. 14,15-eet often locates in Lambda, Cardiovascular system, Blood, Body tissue and Protoplasm. The associated genes with 14,15-eet are CCL2 gene, Cytokine Gene, CYP2C18 gene, CYP2C19 gene and TEK gene. The related lipids are Palmitates.
Cross Reference
Introduction
To understand associated biological information of 14,15-eet, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 14,15-eet?
14,15-eet is suspected in Heart failure, Chronic Obstructive Airway Disease, Pneumonia, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Am. J. Physiol. Endocrinol. Metab. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
- Prostaglandins Other Lipid Mediat. (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 14,15-eet
PubChem Associated disorders and diseases
What pathways are associated with 14,15-eet
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 14,15-eet?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Am. J. Physiol. Lung Cell Mol. Physiol. (2)
- Am. J. Physiol. Endocrinol. Metab. (1)
- Hypertension (1)
- Others (2)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 14,15-eet?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 14,15-eet?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 14,15-eet?
Related references are published most in these journals:
- Am. J. Physiol. Endocrinol. Metab. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
- Hypertension (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 14,15-eet?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 14,15-eet
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gross GJ et al. | Factors mediating remote preconditioning of trauma in the rat heart: central role of the cytochrome p450 epoxygenase pathway in mediating infarct size reduction. | 2013 | J. Cardiovasc. Pharmacol. Ther. | pmid:22407888 |
| Tabet Y et al. | Relationship between bradykinin-induced relaxation and endogenous epoxyeicosanoid synthesis in human bronchi. | 2013 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:23418089 |
| Pidkovka N et al. | Epoxyeicosatrienoic acids (EETs) regulate epithelial sodium channel activity by extracellular signal-regulated kinase 1/2 (ERK1/2)-mediated phosphorylation. | 2013 | J. Biol. Chem. | pmid:23283969 |
| Nelson JW et al. | Soluble epoxide hydrolase dimerization is required for hydrolase activity. | 2013 | J. Biol. Chem. | pmid:23362272 |
| Sander AL et al. | Soluble epoxide hydrolase disruption as therapeutic target for wound healing. | 2013 | J. Surg. Res. | pmid:23122666 |
| Cracowski JL et al. | Involvement of cytochrome epoxygenase metabolites in cutaneous postocclusive hyperemia in humans. | 2013 | J. Appl. Physiol. | pmid:23172029 |
| Gross GJ et al. | Roles of endothelial nitric oxide synthase (eNOS) and mitochondrial permeability transition pore (MPTP) in epoxyeicosatrienoic acid (EET)-induced cardioprotection against infarction in intact rat hearts. | 2013 | J. Mol. Cell. Cardiol. | pmid:23419451 |
| Eid S et al. | 20-HETE and EETs in diabetic nephropathy: a novel mechanistic pathway. | 2013 | PLoS ONE | pmid:23936373 |
| Herse F et al. | Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia. | 2012 | Circulation | pmid:23155181 |
| Li R et al. | Cytochrome P450 2J2 is protective against global cerebral ischemia in transgenic mice. | 2012 | Prostaglandins Other Lipid Mediat. | pmid:23041291 |