D-cycloserine

D-cycloserine is a lipid of Polyketides (PK) class. D-cycloserine is associated with abnormalities such as Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis and Inflammatory Bowel Diseases. The involved functions are known as Cellular Infiltration, Vascular Permeability, Stimulus, antagonists and Kinase Inhibitors [MoA]. D-cycloserine often locates in Tissue membrane, Body tissue, Protoplasm, Endothelium and Cell Wall. The associated genes with D-cycloserine are Genome, serine O-sulfate, Polypeptides, alpha-aminobutyric acid, (S)-isomer and Genes, Reporter. The related lipids are Sphingolipids, Fatty Acids, Sterols, 25-hydroxycholesterol and Fatty Acids, Unsaturated.

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Introduction

To understand associated biological information of D-cycloserine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with D-cycloserine?

D-cycloserine is suspected in Tuberculosis, Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis, Inflammatory Bowel Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with D-cycloserine

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with D-cycloserine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with D-cycloserine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with D-cycloserine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with D-cycloserine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with D-cycloserine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with D-cycloserine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with D-cycloserine

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Authors Title Published Journal PubMed Link
Forsyth JK et al. Effects of Augmenting N-Methyl-D-Aspartate Receptor Signaling on Working Memory and Experience-Dependent Plasticity in Schizophrenia: An Exploratory Study Using Acute d-cycloserine. 2017 Schizophr Bull pmid:28338977
Baker KD and Richardson R Pharmacological evidence that a failure to recruit NMDA receptors contributes to impaired fear extinction retention in adolescent rats. 2017 Neurobiol Learn Mem pmid:27815216
Takiguchi K et al. Association of schizophrenia onset age and white matter integrity with treatment effect of D-cycloserine: a randomized placebo-controlled double-blind crossover study. 2017 BMC Psychiatry pmid:28701225
Shimizu S et al. Glycine-Binding Site Stimulants of NMDA Receptors Alleviate Extrapyramidal Motor Disorders by Activating the Nigrostriatal Dopaminergic Pathway. 2017 Int J Mol Sci pmid:28671605
Kantrowitz JT et al. d-Cycloserine, an NMDA Glutamate Receptor Glycine Site Partial Agonist, Induces Acute Increases in Brain Glutamate Plus Glutamine and GABA Comparable to Ketamine. 2016 Am J Psychiatry pmid:27903101
Goff D The Therapeutic Role of d-Cycloserine in Schizophrenia. 2016 Adv. Pharmacol. pmid:27288073
Otto MW et al. Examining the efficacy of d-cycloserine to augment therapeutic learning in depression. 2016 Contemp Clin Trials pmid:27094721
Yu X et al. Sensititre® MYCOTB MIC plate for drug susceptibility testing of Mycobacterium tuberculosis complex isolates. 2016 Int. J. Tuberc. Lung Dis. pmid:27046713
Smits JA et al. Enhancing panic and smoking reduction treatment with d-cycloserine: Study protocol for a randomized controlled trial. 2016 Contemp Clin Trials pmid:27015966
Fang A and Wilhelm S Antidepressant use with d-Cycloserine may block fear extinction. 2016 Evid Based Ment Health pmid:26792833