| MeSH term | MeSH ID | Detail |
|---|---|---|
| Acute Lung Injury | D055371 | 33 associated lipids |
| Dermatitis, Allergic Contact | D017449 | 20 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Asthma | D001249 | 52 associated lipids |
(-)-Limonene
(-)-limonene is a lipid of Prenol Lipids (PR) class. (-)-limonene often locates in Kinetochores.
Cross Reference
Introduction
To understand associated biological information of (-)-Limonene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (-)-Limonene?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (-)-Limonene
PubChem Associated disorders and diseases
What pathways are associated with (-)-Limonene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (-)-Limonene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (-)-Limonene?
There are no associated biomedical information in the current reference collection.
What lipids are associated with (-)-Limonene?
There are no associated biomedical information in the current reference collection.
What genes are associated with (-)-Limonene?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with (-)-Limonene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (-)-Limonene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Beauchamp PS et al. | California Lomatiums, Part X. Comparison of composition of the hydrodistilled oils from two subspecies of Lomatium mohavense. | 2011 | Nat. Prod. Res. | pmid:21859259 |
| Amiri H | Volatile constituents and antioxidant activity of flowers, stems and leaves of Nasturtium officinale R. Br. | 2012 | Nat. Prod. Res. | pmid:21815727 |
| Kiralan M et al. | Essential oil composition and antiradical activity of the oil of Iraq plants. | 2012 | Nat. Prod. Res. | pmid:21827329 |
| Esmaeili MA et al. | Oxidative stress protective effect of Dracocephalum multicaule essential oil against human cancer cell line. | 2014 | Nat. Prod. Res. | pmid:24484273 |
| Paudel P et al. | Volatile analysis and antimicrobial screening of the parasitic plant Cuscuta reflexa Roxb. from Nepal. | 2014 | Nat. Prod. Res. | pmid:24116676 |
| Mabrouk S et al. | Chemical composition of essential oils from leaves, stems, flower heads and roots of Conyza bonariensis L. from Tunisia. | 2011 | Nat. Prod. Res. | pmid:21240765 |
| Chessa M et al. | Chemical composition and antibacterial activity of the essential oil from Mentha requienii Bentham. | 2013 | Nat. Prod. Res. | pmid:22385272 |
| Orav A et al. | Chemical investigation of the essential oil from berries and needles of common juniper (Juniperus communis L.) growing wild in Estonia. | 2010 | Nat. Prod. Res. | pmid:21104523 |
| Samaneh ET et al. | Composition of essential oils in subterranean organs of three species of Valeriana L. | 2010 | Nat. Prod. Res. | pmid:21104529 |
| Sonboli A et al. | Antibacterial activity of the essential oil and main components of two Dracocephalum species from Iran. | 2012 | Nat. Prod. Res. | pmid:22007732 |
| Khajeh M | Optimisation of supercritical fluid extraction of essential oil components of Diplotaenia cachrydifolia: Box-Behnken design. | 2012 | Nat. Prod. Res. | pmid:22017585 |
| Manassero CA et al. | In vitro comparative analysis of antiproliferative activity of essential oil from mandarin peel and its principal component limonene. | 2013 | Nat. Prod. Res. | pmid:22943501 |
| Gholivand MB et al. | Determination of the chemical composition and in vitro antioxidant activities of essential oil and methanol extracts of Echinophora platyloba DC. | 2011 | Nat. Prod. Res. | pmid:21644173 |
| Shafaghat A | Volatile oil constituents and antibacterial activity of different parts of Falcaria vulgaris Bernh. growing wild in two localities from Iran. | 2011 | Nat. Prod. Res. | pmid:20544497 |
| Thang TD et al. | Constituents of essential oils from the leaves, stem barks and resins of Canarium parvum Leen., and Canarium tramdenanum Dai et Yakovl. (Burseracea) grown in Vietnam. | 2014 | Nat. Prod. Res. | pmid:24443833 |
| Kurahashi T and Yau KW | Co-existence of cationic and chloride components in odorant-induced current of vertebrate olfactory receptor cells. | 1993 | Nature | pmid:7683113 |
| Vaccaro PH | Spectroscopy: Handedness in quick time. | 2009 | Nature | pmid:19295594 |
| Rhee H et al. | Femtosecond characterization of vibrational optical activity of chiral molecules. | 2009 | Nature | pmid:19295604 |
| Attygalle AB et al. | Orange/lemon-scented beetles: opposite enantiomers of limonene as major constituents in the defensive secretion of related carabids. | 2009 | Naturwissenschaften | pmid:19690825 |
| Croteau RB et al. | (-)-Menthol biosynthesis and molecular genetics. | 2005 | Naturwissenschaften | pmid:16292524 |
| Ishida Y and Ozaki M | Aversive odorant causing appetite decrease downregulates tyrosine decarboxylase gene expression in the olfactory receptor neuron of the blowfly, Phormia regina. | 2012 | Naturwissenschaften | pmid:22101840 |
| Kawai F | Odorant suppression of delayed rectifier potassium current in newt olfactory receptor cells. | 1999 | Neurosci. Lett. | pmid:10821641 |
| Kawai F and Miyachi E | Odorants suppress voltage-gated currents in retinal horizontal cells in goldfish. | 2000 | Neurosci. Lett. | pmid:10704765 |
| Shen J et al. | Olfactory stimulation with scent of grapefruit oil affects autonomic nerves, lipolysis and appetite in rats. | 2005 | Neurosci. Lett. | pmid:15862904 |
| Nakamura A et al. | Odour of limonene affects feeding behaviour in the blowfly, Phormia regina. | 2008 | Neurosci. Lett. | pmid:18809464 |
| Duchamp-Viret P and Duchamp A | GABAergic control of odour-induced activity in the frog olfactory bulb: possible GABAergic modulation of granule cell inhibitory action. | 1993 | Neuroscience | pmid:8284042 |
| Ighimi H | [Gallstone solubilizers]. | 1984 | Nihon Geka Gakkai Zasshi | pmid:6503981 |
| Sugata F | [New therapeutic methods--technics, application, efficacy and problems. Litholysis. c) Present status of direct litholytic agents]. | 1987 | Nippon Rinsho | pmid:3118078 |
| Bardon S et al. | Monoterpenes inhibit cell growth, cell cycle progression, and cyclin D1 gene expression in human breast cancer cell lines. | 1998 | Nutr Cancer | pmid:9824849 |
| Hakim IA et al. | Citrus peel use is associated with reduced risk of squamous cell carcinoma of the skin. | 2000 | Nutr Cancer | pmid:11142088 |
| Miller JA et al. | Adipose tissue accumulation of d-limonene with the consumption of a lemonade preparation rich in d-limonene content. | 2010 | Nutr Cancer | pmid:20661827 |
| Fukumoto S et al. | Flavor components of monoterpenes in citrus essential oils enhance the release of monoamines from rat brain slices. | 2006 Feb-Apr | Nutr Neurosci | pmid:16913049 |
| Zhou W et al. | Components of lemon essential oil attenuate dementia induced by scopolamine. | 2009 | Nutr Neurosci | pmid:19356307 |
| d-limonene, an anticarcinogenic terpene. | 1988 | Nutr. Rev. | pmid:3067145 | |
| Lewis KA and Hohl RJ | Modulation of RAS expression in human malignant cells by dietary supplements. | 1997 | Nutrition | pmid:9357036 |
| D'Erme AM et al. | Contact dermatitis due to dipentene and pine oil in an automobile mechanic. | 2012 | Occup Environ Med | pmid:22146991 |
| Tammaro A et al. | Archer dermatitis: a new case of allergic contact dermatitis. | 2013 | Occup Environ Med | pmid:23873984 |
| Giri RK et al. | d-limonene chemoprevention of hepatocarcinogenesis in AKR mice: inhibition of c-jun and c-myc. | 1999 Sep-Oct | Oncol. Rep. | pmid:10425313 |
| Jia SS et al. | Induction of apoptosis by D-limonene is mediated by inactivation of Akt in LS174T human colon cancer cells. | 2013 | Oncol. Rep. | pmid:23117412 |
| Vajrabhaya LO et al. | Cytotoxicity evaluation of gutta-percha solvents: Chloroform and GP-Solvent (limonene). | 2004 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod | pmid:15583552 |
| Wender PA and Zhang L | Asymmetric total synthesis of (+)-aphanamol I based on the transition metal catalyzed [5 + 2] cycloaddition of allenes and vinylcyclopropanes. | 2000 | Org. Lett. | pmid:10930274 |
| Pitsinos EN et al. | Enantioselective total synthesis of (-)-laurenditerpenol. | 2012 | Org. Lett. | pmid:22905649 |
| Wender PA et al. | Asymmetric synthesis of the tricyclic core of NGF-inducing cyathane diterpenes via a transition-metal-catalyzed [5 + 2] cycloaddition. | 2001 | Org. Lett. | pmid:11418060 |
| Bai J et al. | Protective Effect of D-Limonene against Oxidative Stress-Induced Cell Damage in Human Lens Epithelial Cells via the p38 Pathway. | 2016 | Oxid Med Cell Longev | pmid:26682012 |
| Govindarajan M et al. | Chemical composition and larvicidal activity of essential oil from Mentha spicata (Linn.) against three mosquito species. | 2012 | Parasitol. Res. | pmid:22139403 |
| Gannu R et al. | In vitro permeation of carvedilol through porcine skin: effect of vehicles and penetration enhancers. | 2008 Jul-Aug | PDA J Pharm Sci Technol | pmid:19174954 |
| Kostyukovsky M et al. | Activation of octopaminergic receptors by essential oil constituents isolated from aromatic plants: possible mode of action against insect pests. | 2002 | Pest Manag. Sci. | pmid:12449528 |
| Miresmailli S et al. | Comparative toxicity of Rosmarinus officinalis L. essential oil and blends of its major constituents against Tetranychus urticae Koch (Acari: Tetranychidae) on two different host plants. | 2006 | Pest Manag. Sci. | pmid:16470541 |
| Cheng SS et al. | Insecticidal activities of leaf and twig essential oils from Clausena excavata against Aedes aegypti and Aedes albopictus larvae. | 2009 | Pest Manag. Sci. | pmid:19115256 |
| López S et al. | Electrophysiological and behavioural responses of Pityophthorus pubescens (Coleoptera: Scolytinae) to (E,E)-α-farnesene, (R)-(+)-limonene and (S)-(-)-verbenone in Pinus radiata (Pinaceae) stands in northern Spain. | 2013 | Pest Manag. Sci. | pmid:22764125 |
| Rastogi SK and Singh J | Iontophoretic enhancement of leuprolide acetate by fatty acids, limonene, and depilatory lotions through porcine epidermis. | 2004 | Pharm Dev Technol | pmid:15581070 |
| Zhang CF et al. | Effects of enantiomer and isomer permeation enhancers on transdermal delivery of ligustrazine hydrochloride. | 2006 | Pharm Dev Technol | pmid:17101512 |
| Krishnaiah YS et al. | Studies on optimizing in vitro transdermal permeation of ondansetron hydrochloride using nerodilol, carvone, and limonene as penetration enhancers. | 2008 | Pharm Dev Technol | pmid:18484486 |
| Rastogi SK and Singh J | Effect of chemical penetration enhancer and iontophoresis on the in vitro percutaneous absorption enhancement of insulin through porcine epidermis. | 2005 | Pharm Dev Technol | pmid:15776817 |
| Erdal MS et al. | Impacts of chemical enhancers on skin permeation and deposition of terbinafine. | 2014 | Pharm Dev Technol | pmid:23841559 |
| Koyama Y et al. | Comparative analysis of percutaneous absorption enhancement by d-limonene and oleic acid based on a skin diffusion model. | 1994 | Pharm. Res. | pmid:8008702 |
| Si A et al. | Effects of NMDA receptor antagonists on olfactory learning and memory in the honeybee (Apis mellifera). | 2004 | Pharmacol. Biochem. Behav. | pmid:14751445 |
| Lima NG et al. | Anxiolytic-like activity and GC-MS analysis of (R)-(+)-limonene fragrance, a natural compound found in foods and plants. | 2013 | Pharmacol. Biochem. Behav. | pmid:22995322 |
| Bell GD | Cholelitholytic agents. | 1983 | Pharmacol. Ther. | pmid:6419241 |
| Whysner J and Williams GM | d-limonene mechanistic data and risk assessment: absolute species-specific cytotoxicity, enhanced cell proliferation, and tumor promotion. | 1996 | Pharmacol. Ther. | pmid:8910952 |
| Souza MC et al. | Evaluation of anti-inflammatory activity of essential oils from two Asteraceae species. | 2003 | Pharmazie | pmid:12967039 |
| Krishnaiah YS et al. | Effect of limonene on the in vitro permeation of nicardipine hydrochloride across the excised rat abdominal skin. | 2002 | Pharmazie | pmid:12561249 |
| Krishnaiah YS et al. | In vitro percutaneous permeability enhancement of nimodipine by limonene across the excised rat abdominal skin. | 2004 | Pharmazie | pmid:15638083 |
| Liu T et al. | Bioequivalence evaluation of two D-limonene capsule formulations in healthy Chinese volunteers. | 2008 | Pharmazie | pmid:18972832 |
| Walser ML et al. | High-resolution mass spectrometric analysis of secondary organic aerosol produced by ozonation of limonene. | 2008 | Phys Chem Chem Phys | pmid:18259641 |
| Bateman AP et al. | Photolytic processing of secondary organic aerosols dissolved in cloud droplets. | 2011 | Phys Chem Chem Phys | pmid:21617794 |
| Maksymiuk CS et al. | Secondary organic aerosol formation from multiphase oxidation of limonene by ozone: mechanistic constraints via two-dimensional heteronuclear NMR spectroscopy. | 2009 | Phys Chem Chem Phys | pmid:19727487 |
| Bateman AP et al. | Time-resolved molecular characterization of limonene/ozone aerosol using high-resolution electrospray ionization mass spectrometry. | 2009 | Phys Chem Chem Phys | pmid:19727500 |
| Śmiałek MA et al. | Limonene: electronic state spectroscopy by high-resolution vacuum ultraviolet photoabsorption, electron scattering, He(I) photoelectron spectroscopy and ab initio calculations. | 2012 | Phys Chem Chem Phys | pmid:22231475 |
| Belkin MA et al. | Sum-frequency vibrational spectroscopy on chiral liquids: a novel technique to probe molecular chirality. | 2000 | Phys. Rev. Lett. | pmid:11082574 |
| Laing DG et al. | Odor masking in the rat. | 1989 | Physiol. Behav. | pmid:2780835 |
| Youngentob SL et al. | Odorant threshold following methyl bromide-induced lesions of the olfactory epithelium. | 1997 | Physiol. Behav. | pmid:9383109 |
| Tankeu S et al. | Vibrational spectroscopy as a rapid quality control method for Melaleuca alternifolia cheel (tea tree oil). | 2014 Jan-Feb | Phytochem Anal | pmid:23934710 |
| Moradi M et al. | Comparison of headspace solid-phase microextraction, headspace single-drop microextraction and hydrodistillation for chemical screening of volatiles in Myrtus communis L. | 2012 Jul-Aug | Phytochem Anal | pmid:22069217 |
| Mahmoud SS et al. | Cosuppression of limonene-3-hydroxylase in peppermint promotes accumulation of limonene in the essential oil. | 2004 | Phytochemistry | pmid:15003417 |
| Maffei M et al. | Effect of Mentha x piperita essential oil and monoterpenes on cucumber root membrane potential. | 2001 | Phytochemistry | pmid:11672734 |
| Zhao T et al. | The influence of Ceratocystis polonica inoculation and methyl jasmonate application on terpene chemistry of Norway spruce, Picea abies. | 2010 | Phytochemistry | pmid:20557909 |
| Demyttenaere JC et al. | Biotransformation of (R)-(+)- and (S)-(-)-limonene by fungi and the use of solid phase microextraction for screening. | 2001 | Phytochemistry | pmid:11382235 |
| Carter OA et al. | Monoterpene biosynthesis pathway construction in Escherichia coli. | 2003 | Phytochemistry | pmid:12943759 |
| Chaiyana W and Okonogi S | Inhibition of cholinesterase by essential oil from food plant. | 2012 | Phytomedicine | pmid:22510493 |
| Slinski SL et al. | The Effect of Resin and Monoterpenes on Spore Germination and Growth in Fusarium circinatum. | 2015 | Phytopathology | pmid:25163010 |
| Conforti F et al. | In vitro activities of Citrus medica L. cv. Diamante (Diamante citron) relevant to treatment of diabetes and Alzheimer's disease. | 2007 | Phytother Res | pmid:17236166 |
| Manuele MG et al. | Effect of Tilia x viridis flower extract on the proliferation of a lymphoma cell line and on normal murine lymphocytes: contribution of monoterpenes, especially limonene. | 2008 | Phytother Res | pmid:18688792 |
| Kumar P et al. | Kinetics of enzyme inhibition by active molluscicidal agents ferulic acid, umbelliferone, eugenol and limonene in the nervous tissue of snail Lymnaea acuminata. | 2009 | Phytother Res | pmid:18814203 |
| Satou T et al. | Organ accumulation in mice after inhalation of single or mixed essential oil compounds. | 2013 | Phytother Res | pmid:22581512 |
| Cabral C et al. | Essential oil of Juniperus communis subsp. alpina (Suter) ÄŒelak needles: chemical composition, antifungal activity and cytotoxicity. | 2012 | Phytother Res | pmid:22294341 |
| Manuele MG et al. | Mechanism of the antiproliferative action of limonene on a lymphoma cell line: participation of nitric oxide. antiproliferative action of limonene on a lymphoma cell line. | 2009 | Phytother Res | pmid:19145635 |
| Asnaashari S et al. | Essential oil from Citrus aurantifolia prevents ketotifen-induced weight-gain in mice. | 2010 | Phytother Res | pmid:20623616 |
| Noe SM et al. | Foliar limonene uptake scales positively with leaf lipid content: "non-emitting" species absorb and release monoterpenes. | 2008 | Plant Biol (Stuttg) | pmid:17564947 |
| Ohara K et al. | Monoterpene engineering in a woody plant Eucalyptus camaldulensis using a limonene synthase cDNA. | 2010 | Plant Biotechnol. J. | pmid:20055958 |
| Byers KJ et al. | Floral volatile alleles can contribute to pollinator-mediated reproductive isolation in monkeyflowers (Mimulus). | 2014 | Plant J. | pmid:25319242 |
| Chen F et al. | Characterization of a root-specific Arabidopsis terpene synthase responsible for the formation of the volatile monoterpene 1,8-cineole. | 2004 | Plant Physiol. | pmid:15299125 |
| RodrÃguez A et al. | Terpene down-regulation triggers defense responses in transgenic orange leading to resistance against fungal pathogens. | 2014 | Plant Physiol. | pmid:24192451 |
| RodrÃguez A et al. | Terpene down-regulation in orange reveals the role of fruit aromas in mediating interactions with insect herbivores and pathogens. | 2011 | Plant Physiol. | pmid:21525333 |
| Niinemets U et al. | Stomatal constraints may affect emission of oxygenated monoterpenoids from the foliage of Pinus pinea. | 2002 | Plant Physiol. | pmid:12428002 |
| RodrÃguez A et al. | Resistance to pathogens in terpene down-regulated orange fruits inversely correlates with the accumulation of D-limonene in peel oil glands. | 2015 | Plant Signal Behav | pmid:26023857 |
| RodrÃguez A et al. | The monoterpene limonene in orange peels attracts pests and microorganisms. | 2011 | Plant Signal Behav | pmid:22212123 |
| Miller B et al. | First isolation of an isoprene synthase gene from poplar and successful expression of the gene in Escherichia coli. | 2001 | Planta | pmid:11506373 |
| Cariddi L et al. | Monoterpenes isolated from Minthostachys verticillata (Griseb.) Epling essential oil modulates immediate-type hypersensitivity responses in vitro and in vivo. | 2011 | Planta Med. | pmid:21590652 |
| Moraes Jd et al. | Anthelmintic activity of the natural compound (+)-limonene epoxide against Schistosoma mansoni. | 2013 | Planta Med. | pmid:23408270 |