| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Dermatitis, Allergic Contact | D017449 | 20 associated lipids |
| Acute Lung Injury | D055371 | 33 associated lipids |
(-)-Limonene
(-)-limonene is a lipid of Prenol Lipids (PR) class. (-)-limonene often locates in Kinetochores.
Cross Reference
Introduction
To understand associated biological information of (-)-Limonene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (-)-Limonene?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (-)-Limonene
PubChem Associated disorders and diseases
What pathways are associated with (-)-Limonene
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (-)-Limonene?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (-)-Limonene?
There are no associated biomedical information in the current reference collection.
What lipids are associated with (-)-Limonene?
There are no associated biomedical information in the current reference collection.
What genes are associated with (-)-Limonene?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with (-)-Limonene?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (-)-Limonene
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen H et al. | Pharmacokinetics of d-limonene in the rat by GC-MS assay. | 1998 | J Pharm Biomed Anal | pmid:9682146 |
| Estell RE et al. | Effects of volatile compounds on consumption of alfalfa pellets by sheep. | 1998 | J. Anim. Sci. | pmid:9464903 |
| van Lieshout EM et al. | Effects of the sulforaphane analog compound 30, indole-3-carbinol, D-limonene or relafen on glutathione S-transferases and glutathione peroxidase of the rat digestive tract. | 1998 | Biochim. Biophys. Acta | pmid:9545594 |
| Lehman-McKeeman LD et al. | 2-sec-butyl-4,5-dihydrothiazole is a ligand for mouse urinary protein and rat alpha 2u-globulin: physiological and toxicological relevance. | 1998 | Toxicol. Appl. Pharmacol. | pmid:9512724 |
| Wakelin SH et al. | Allergic contact dermatitis from d-limonene in a laboratory technician. | 1998 | Contact Derm. | pmid:9536411 |
| Kaur M et al. | Receptor-Ck-dependent regulation of genes involved in the cell cycle. | 1998 | Mol. Cell. Biochem. | pmid:9562250 |
| Savithiry N et al. | Degradation of pinene by Bacillus pallidus BR425. | 1998 | Biodegradation | pmid:10192895 |
| Zhang T et al. | [Influence of fry-processing on outward character and inner quality of volatile oil containing drugs such as fructus Viticis, etc]. | 1998 | Zhongguo Zhong Yao Za Zhi | pmid:11243151 |
| Chen X et al. | [Effect of d-limonene, Salvia miltiorrhiza and turmeric derivatives on membrane association of Ras gene product and gap junction intercellular communication]. | 1998 | Yao Xue Xue Bao | pmid:12016941 |
| Diez I et al. | Influence of d-limonene on the transdermal penetration of felodipine. | 1998 Jan-Mar | Eur J Drug Metab Pharmacokinet | pmid:9625266 |
| Morse MA | Inhibition of NNK-induced lung tumorigenesis by modulators of NNK activation. | 1998 Jul-Aug | Exp. Lung Res. | pmid:9659585 |
| Oshiro Y et al. | Exploration of the transformation potential of a unique male rat protein alpha2u-globulin using hamster embryonic cells. | 1998 May-Jun | Toxicol Pathol | pmid:9608644 |
| Zhao K and Singh J | In vitro percutaneous absorption enhancement of propranolol hydrochloride through porcine epidermis by terpenes/ethanol. | 1999 | J Control Release | pmid:10528073 |
| Chen X et al. | Inhibition of farnesyl protein transferase and P21ras memebrane association by d-limonene in human pancreas tumor cells in vitro. | 1999 | Chin. Med. Sci. J. | pmid:12903812 |
| End DW | Farnesyl protein transferase inhibitors and other therapies targeting the Ras signal transduction pathway. | 1999 | Invest New Drugs | pmid:10665477 |
| Simándi B et al. | Supercritical carbon dioxide extraction and fractionation of fennel oil. | 1999 | J. Agric. Food Chem. | pmid:10564030 |
| Roy A | Chemoenzymatic synthesis of homochiral (R)- and (S)-karahanaenol from (R)-limonene. | 1999 | J. Agric. Food Chem. | pmid:10606597 |
| d-limonene. | 1999 | IARC Monogr Eval Carcinog Risks Hum | pmid:10804960 | |
| Kawai F | Odorant suppression of delayed rectifier potassium current in newt olfactory receptor cells. | 1999 | Neurosci. Lett. | pmid:10821641 |
| Safety assessment and potential health benefits of food components based on selected scientific criteria. ILSI North America Technical Committee on Food Components for Health Promotion. | 1999 | Crit Rev Food Sci Nutr | pmid:10367185 | |
| Bhatia KS and Singh J | Effect of linolenic acid/ethanol or limonene/ethanol and iontophoresis on the in vitro percutaneous absorption of LHRH and ultrastructure of human epidermis. | 1999 | Int J Pharm | pmid:10370194 |
| Greene-McDowelle DM et al. | The effects of selected cotton-leaf volatiles on growth, development and aflatoxin production of Aspergillus parasiticus. | 1999 | Toxicon | pmid:10340828 |
| Laska M and Teubner P | Olfactory discrimination ability of human subjects for ten pairs of enantiomers. | 1999 | Chem. Senses | pmid:10321817 |
| Lupien S et al. | Regiospecific cytochrome P450 limonene hydroxylases from mint (Mentha) species: cDNA isolation, characterization, and functional expression of (-)-4S-limonene-3-hydroxylase and (-)-4S-limonene-6-hydroxylase. | 1999 | Arch. Biochem. Biophys. | pmid:10415126 |
| Yano H et al. | Attenuation by d-limonene of sodium chloride-enhanced gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. | 1999 | Int. J. Cancer | pmid:10417763 |
| Eummer JT et al. | Novel limonene phosphonate and farnesyl diphosphate analogues: design, synthesis, and evaluation as potential protein-farnesyl transferase inhibitors. | 1999 | Bioorg. Med. Chem. | pmid:10218815 |
| Onken J and Berger RG | Effects of R-(+)-limonene on submerged cultures of the terpene transforming basidiomycete Pleurotus sapidus. | 1999 | J. Biotechnol. | pmid:10361724 |
| Uedo N et al. | Inhibition by D-limonene of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. | 1999 | Cancer Lett. | pmid:10374833 |
| Duchamp-Viret P et al. | Odor response properties of rat olfactory receptor neurons. | 1999 | Science | pmid:10381881 |
| van der Werf MJ et al. | Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene. | 1999 | Appl. Environ. Microbiol. | pmid:10224006 |
| Karlberg AT et al. | Regulatory classification of substances oxidized to skin sensitizers on exposure to air. | 1999 | Contact Derm. | pmid:10208503 |
| Nilsson U et al. | Are contact allergens stable in patch test preparations? Investigation of the degradation of d-limonene hydroperoxides in petrolatum. | 1999 | Contact Derm. | pmid:10073439 |
| Hardcastle IR et al. | Inhibition of protein prenylation by metabolites of limonene. | 1999 | Biochem. Pharmacol. | pmid:10075086 |
| Barnhart ET et al. | Evaluation of potential disinfectants for preslaughter broiler crop decontamination. | 1999 | Poult. Sci. | pmid:10023743 |
| Crowell PL | Prevention and therapy of cancer by dietary monoterpenes. | 1999 | J. Nutr. | pmid:10082788 |
| Donaldson MJ et al. | XR3054, structurally related to limonene, is a novel inhibitor of farnesyl protein transferase. | 1999 | Eur. J. Cancer | pmid:10533487 |
| Giri RK et al. | d-limonene chemoprevention of hepatocarcinogenesis in AKR mice: inhibition of c-jun and c-myc. | 1999 Sep-Oct | Oncol. Rep. | pmid:10425313 |
| Garti N et al. | Some characteristics of sugar ester nonionic microemulsions in view of possible food applications. | 2000 | J. Agric. Food Chem. | pmid:10995296 |
| Gao Y et al. | [A study on the chemical components of essential oil of oak moss concrete by gas chromatography/mass spectrometry]. | 2000 | Se Pu | pmid:12541566 |
| Yang D et al. | [Chemical composition of essential oil in stems, leaves and flowers of Agastache rugosa]. | 2000 | Zhong Yao Cai | pmid:12575134 |
| Franco MR and Shibamoto T | Volatile composition of some Brazilian fruits: umbu-caja (Spondias citherea), camu-camu (Myrciaria dubia), Araça-boi (Eugenia stipitata), and Cupuaçu (Theobroma grandiflorum). | 2000 | J. Agric. Food Chem. | pmid:10775382 |
| Larsen ST et al. | Effects of R-(+)- and S-(-)-limonene on the respiratory tract in mice. | 2000 | Hum Exp Toxicol | pmid:11125716 |
| Belkin MA et al. | Sum-frequency vibrational spectroscopy on chiral liquids: a novel technique to probe molecular chirality. | 2000 | Phys. Rev. Lett. | pmid:11082574 |
| Jouenne E and Crouzet J | Determination of apparent binding constants for aroma compounds with beta-lactoglobulin by dynamic coupled column liquid chromatography. | 2000 | J. Agric. Food Chem. | pmid:11087491 |
| Cheong TK and Oriel PJ | Cloning and expression of the limonene hydroxylase of Bacillus stearothermophilus BR388 and utilization in two-phase limonene conversions. | 2000 | Appl. Biochem. Biotechnol. | pmid:10849845 |
| AramendÃa MA et al. | The surface structure of catalysts activated with hydrogen donors as elucidated by multinuclear solid-state NMR. | 2000 | Solid State Nucl Magn Reson | pmid:10928626 |
| Wender PA and Zhang L | Asymmetric total synthesis of (+)-aphanamol I based on the transition metal catalyzed [5 + 2] cycloaddition of allenes and vinylcyclopropanes. | 2000 | Org. Lett. | pmid:10930274 |
| Coleman WM and Lawrence BM | Examination of the enantiomeric distribution of certain monoterpene hydrocarbons in selected essential oils by automated solid-phase microextraction-chiral gas chromatography-mass selective detection. | 2000 | J Chromatogr Sci | pmid:10702916 |
| Hirano Y et al. | Electroencephalographic olfactometry (EEGO) analysis of odour responses in dogs. | 2000 | Res. Vet. Sci. | pmid:11124098 |
| Kawai F and Miyachi E | Odorants suppress voltage-gated currents in retinal horizontal cells in goldfish. | 2000 | Neurosci. Lett. | pmid:10704765 |
| van der Werf MJ and Boot AM | Metabolism of carveol and dihydrocarveol in Rhodococcus erythropolis DCL14. | 2000 | Microbiology (Reading, Engl.) | pmid:10832640 |
| Jouenne E and Crouzet J | Effect of pH on retention of aroma compounds by beta-lactoglobulin. | 2000 | J. Agric. Food Chem. | pmid:10775385 |
| Witschi H | Successful and not so successful chemoprevention of tobacco smoke-induced lung tumors. | 2000 | Exp. Lung Res. | pmid:11195468 |
| Wainman T et al. | Ozone and limonene in indoor air: a source of submicron particle exposure. | 2000 | Environ. Health Perspect. | pmid:11133393 |
| Hakim IA et al. | Citrus peel use is associated with reduced risk of squamous cell carcinoma of the skin. | 2000 | Nutr Cancer | pmid:11142088 |
| Kawahara H et al. | Identification of a compound in Chamaecyparis taiwanensis inhibiting the ice-nucleating activity of Pseudomonas fluorescens KUIN-1. | 2000 | Biosci. Biotechnol. Biochem. | pmid:11210129 |
| Weschler CJ and Shields HC | The influence of ventilation on reactions among indoor pollutants: modeling and experimental observations. | 2000 | Indoor Air | pmid:11980107 |
| Leskey TC et al. | Evaluation of individual components of plum odor as potential attractants for adult plum curculios. | 2001 | J. Chem. Ecol. | pmid:11382056 |
| Shao H et al. | [Study of chemical constituents of essential oil from flowers of Mikania micrantha H.B.K]. | 2001 | Zhong Yao Cai | pmid:12587209 |
| Seebungkert B and Lynch JW | A common inhibitory binding site for zinc and odorants at the voltage-gated K(+) channel of rat olfactory receptor neurons. | 2001 | Eur. J. Neurosci. | pmid:11553285 |
| Maffei M et al. | Effect of Mentha x piperita essential oil and monoterpenes on cucumber root membrane potential. | 2001 | Phytochemistry | pmid:11672734 |
| Cal K et al. | In vitro studies on penetration of terpenes from matrix-type transdermal systems through human skin. | 2001 | Int J Pharm | pmid:11472817 |
| Ayhan Z et al. | Flavor, color, and vitamin C retention of pulsed electric field processed orange juice in different packaging materials. | 2001 | J. Agric. Food Chem. | pmid:11262010 |
| Bertolini AC et al. | Stability of monoterpenes encapsulated in gum Arabic by spray-drying. | 2001 | J. Agric. Food Chem. | pmid:11262028 |
| Puglia C et al. | Evaluation of in vitro percutaneous absorption of lorazepam and clonazepam from hydro-alcoholic gel formulations. | 2001 | Int J Pharm | pmid:11576770 |
| Miller B et al. | First isolation of an isoprene synthase gene from poplar and successful expression of the gene in Escherichia coli. | 2001 | Planta | pmid:11506373 |
| Clausen PA et al. | Chemical and biological evaluation of a reaction mixture of R-(+)-limonene/ozone: formation of strong airway irritants. | 2001 | Environ Int | pmid:11485219 |
| Ahro M et al. | Low-resolution gas-phase FT-IR method for the determination of the limonene/carvone ratio in supercritical CO2-extracted caraway fruit oils. | 2001 | J. Agric. Food Chem. | pmid:11453743 |
| Mars AE et al. | Bioconversion of limonene to increased concentrations of perillic acid by Pseudomonas putida GS1 in a fed-batch reactor. | 2001 | Appl. Microbiol. Biotechnol. | pmid:11499915 |
| Moura IC et al. | Limonene arrests parasite development and inhibits isoprenylation of proteins in Plasmodium falciparum. | 2001 | Antimicrob. Agents Chemother. | pmid:11502528 |
| Tandlich R et al. | The effect of terpenes on the biodegradation of polychlorinated biphenyls by Pseudomonas stutzeri. | 2001 | Chemosphere | pmid:11545520 |
| Warscheid B and Hoffmann T | Structural elucidation of monoterpene oxidation products by ion trap fragmentation using on-line atmospheric pressure chemical ionisation mass spectrometry in the negative ion mode. | 2001 | Rapid Commun. Mass Spectrom. | pmid:11746892 |
| Linster C et al. | Perceptual correlates of neural representations evoked by odorant enantiomers. | 2001 | J. Neurosci. | pmid:11739591 |
| Pino JA and Marbot R | Volatile flavor constituents of acerola (Malpighia emarginata DC.) fruit. | 2001 | J. Agric. Food Chem. | pmid:11743778 |
| Fietzek C et al. | Chiral discrimination of limonene by use of beta-cyclodextrin-coated quartz-crystal-microbalances (QCMs) and data evaluation by artificial neuronal networks. | 2001 | Fresenius J Anal Chem | pmid:11605760 |
| Fritz TM et al. | [Allergic contact dermatitis to cosmetics containing Melaleuca alternifolia (tea tree oil)]. | 2001 | Ann Dermatol Venereol | pmid:11275586 |
| Maruyama T et al. | Molecular cloning, functional expression and characterization of d-limonene synthase from Schizonepeta tenuifolia. | 2001 | Biol. Pharm. Bull. | pmid:11305598 |
| Heuberger E et al. | Effects of chiral fragrances on human autonomic nervous system parameters and self-evaluation. | 2001 | Chem. Senses | pmid:11287388 |
| Choi HS and Sawamura M | Volatile flavor components of ripe and overripe ki-mikans (Citrus flaviculpus Hort. ex Tanaka) in comparison with Hyuganatsu (Citrus tamurana Hort. ex Tanaka). | 2001 | Biosci. Biotechnol. Biochem. | pmid:11272845 |
| Wüst M et al. | Hydroxylation of limonene enantiomers and analogs by recombinant (-)-limonene 3- and 6-hydroxylases from mint (Mentha) species: evidence for catalysis within sterically constrained active sites. | 2001 | Arch. Biochem. Biophys. | pmid:11368174 |
| Choi HS et al. | Characterization of the odor-active volatiles in citrus Hyuganatsu (Citrus tamurana Hort. ex Tanaka). | 2001 | J. Agric. Food Chem. | pmid:11368611 |
| van der Werf MJ et al. | Xanthobacter sp. C20 contains a novel bioconversion pathway for limonene. | 2001 | J. Biotechnol. | pmid:11090685 |
| Turner SD et al. | The male rat carcinogens limonene and sodium saccharin are not mutagenic to male Big Blue rats. | 2001 | Mutagenesis | pmid:11420401 |
| Demyttenaere JC et al. | Biotransformation of (R)-(+)- and (S)-(-)-limonene by fungi and the use of solid phase microextraction for screening. | 2001 | Phytochemistry | pmid:11382235 |
| Rubino M et al. | Permeation of oxygen, water vapor, and limonene through printed and unprinted biaxially oriented polypropylene films. | 2001 | J. Agric. Food Chem. | pmid:11410006 |
| Chatterjee T and Bhattacharyya DK | Biotransformation of limonene by Pseudomonas putida. | 2001 | Appl. Microbiol. Biotechnol. | pmid:11414318 |
| Wender PA et al. | Asymmetric synthesis of the tricyclic core of NGF-inducing cyathane diterpenes via a transition-metal-catalyzed [5 + 2] cycloaddition. | 2001 | Org. Lett. | pmid:11418060 |
| Kaji I et al. | Inhibition by d-limonene of experimental hepatocarcinogenesis in Sprague-Dawley rats does not involve p21(ras) plasma membrane association. | 2001 | Int. J. Cancer | pmid:11433412 |
| Trapp SC and Croteau RB | Genomic organization of plant terpene synthases and molecular evolutionary implications. | 2001 | Genetics | pmid:11404343 |
| Duetz WA et al. | Biotransformation of D-limonene to (+) trans-carveol by toluene-grown Rhodococcus opacus PWD4 cells. | 2001 | Appl. Environ. Microbiol. | pmid:11375201 |
| Warbrick EV et al. | Preliminary assessment of the skin sensitizing activity of selected rodent carcinogens using the local lymph node assay. | 2001 | Toxicology | pmid:11376865 |
| Spernath A et al. | Food-grade microemulsions based on nonionic emulsifiers: media to enhance lycopene solubilization. | 2002 | J. Agric. Food Chem. | pmid:12405797 |
| Matura M et al. | Oxidized citrus oil (R-limonene): a frequent skin sensitizer in Europe. | 2002 | J. Am. Acad. Dermatol. | pmid:12399762 |
| Hakim IA et al. | Development of a questionnaire and a database for assessing dietary d-limonene intake. | 2002 | Public Health Nutr | pmid:12633519 |
| Shimada T et al. | Species differences in the metabolism of (+)- and (-)-limonenes and their metabolites, carveols and carvones, by cytochrome P450 enzymes in liver microsomes of mice, rats, guinea pigs, rabbits, dogs, monkeys, and humans. | 2002 | Drug Metab. Pharmacokinet. | pmid:15618705 |
| Chow HH et al. | Pharmacokinetics of perillic acid in humans after a single dose administration of a citrus preparation rich in d-limonene content. | 2002 | Cancer Epidemiol. Biomarkers Prev. | pmid:12433729 |
| Dybing E | Development and implementation of the IPCS conceptual framework for evaluating mode of action of chemical carcinogens. | 2002 | Toxicology | pmid:12505296 |
| Seebungkert B and Lynch JW | Effects of polyunsaturated fatty acids on voltage-gated K+ and Na+ channels in rat olfactory receptor neurons. | 2002 | Eur. J. Neurosci. | pmid:12473076 |
| Hamada M et al. | Distribution and immune responses resulting from oral administration of D-limonene in rats. | 2002 | J. Nutr. Sci. Vitaminol. | pmid:12171437 |
| Lee JA et al. | Acute necrotizing dermatitis and septicemia after application of a d-limonene-based insecticidal shampoo in a cat. | 2002 | J. Am. Vet. Med. Assoc. | pmid:12118590 |