(-)-Limonene

(-)-limonene is a lipid of Prenol Lipids (PR) class. (-)-limonene often locates in Kinetochores.

Cross Reference

Introduction

To understand associated biological information of (-)-Limonene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Limonene

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Cataract D002386 34 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Asthma D001249 52 associated lipids
Neuroblastoma D009447 66 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Hypolipoproteinemias D007009 9 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Acute Lung Injury D055371 33 associated lipids
Per page 10 20 | Total 11

PubChem Associated disorders and diseases

What pathways are associated with (-)-Limonene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Limonene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

What lipids are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

What genes are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Limonene

Download all related citations
Per page 10 20 50 100 | Total 1129
Authors Title Published Journal PubMed Link
Macchioni F et al. Acaricidal activity of pine essential oils and their main components against Tyrophagus putrescentiae, a stored food mite. 2002 J. Agric. Food Chem. pmid:12137480
Zawirska-Wojtasiak R and Wasowicz E Estimation of the main dill seeds odorant carvone by solid-phase microextraction and gas chromatography. 2002 Nahrung pmid:12428454
Krishnaiah YS et al. Influence of limonene on the bioavailability of nicardipine hydrochloride from membrane-moderated transdermal therapeutic systems in human volunteers. 2002 Int J Pharm pmid:12429488
Spernath A et al. Food-grade microemulsions based on nonionic emulsifiers: media to enhance lycopene solubilization. 2002 J. Agric. Food Chem. pmid:12405797
Matura M et al. Oxidized citrus oil (R-limonene): a frequent skin sensitizer in Europe. 2002 J. Am. Acad. Dermatol. pmid:12399762
Hakim IA et al. Development of a questionnaire and a database for assessing dietary d-limonene intake. 2002 Public Health Nutr pmid:12633519
Shimada T et al. Species differences in the metabolism of (+)- and (-)-limonenes and their metabolites, carveols and carvones, by cytochrome P450 enzymes in liver microsomes of mice, rats, guinea pigs, rabbits, dogs, monkeys, and humans. 2002 Drug Metab. Pharmacokinet. pmid:15618705
Krishnaiah YS et al. Effect of limonene on the in vitro permeation of nicardipine hydrochloride across the excised rat abdominal skin. 2002 Pharmazie pmid:12561249
Kostyukovsky M et al. Activation of octopaminergic receptors by essential oil constituents isolated from aromatic plants: possible mode of action against insect pests. 2002 Pest Manag. Sci. pmid:12449528
Chow HH et al. Pharmacokinetics of perillic acid in humans after a single dose administration of a citrus preparation rich in d-limonene content. 2002 Cancer Epidemiol. Biomarkers Prev. pmid:12433729
Dybing E Development and implementation of the IPCS conceptual framework for evaluating mode of action of chemical carcinogens. 2002 Toxicology pmid:12505296
Kelling FJ et al. Background odour induces adaptation and sensitization of olfactory receptors in the antennae of houseflies. 2002 Med. Vet. Entomol. pmid:12109710
Linster C et al. Spontaneous versus reinforced olfactory discriminations. 2002 J. Neurosci. pmid:12177181
Shim SC et al. Diastereoselectivity control in photosensitized addition of methanol to (R)-(+)-limonene. 2002 J. Org. Chem. pmid:12153274
Paolesse R et al. Preparation and self-assembly of chiral porphyrin diads on the gold electrodes of quartz crystal microbalances: a novel potential approach to the development of enantioselective chemical sensors. 2002 Chemistry pmid:12180326
Seebungkert B and Lynch JW Effects of polyunsaturated fatty acids on voltage-gated K+ and Na+ channels in rat olfactory receptor neurons. 2002 Eur. J. Neurosci. pmid:12473076
Warscheid B and Hoffmann T Direct analysis of highly oxidised organic aerosol constituents by on-line ion trap mass spectrometry in the negative-ion mode. 2002 Rapid Commun. Mass Spectrom. pmid:11870886
Witschi H et al. Expression of cyclin D1/2 in the lungs of strain A/J mice fed chemopreventive agents. 2002 Carcinogenesis pmid:11872634
Wüst M and Croteau RB Hydroxylation of specifically deuterated limonene enantiomers by cytochrome p450 limonene-6-hydroxylase reveals the mechanism of multiple product formation. 2002 Biochemistry pmid:11827526
Lota ML et al. Volatile components of peel and leaf oils of lemon and lime species. 2002 J. Agric. Food Chem. pmid:11829647
Lu M et al. Muscle relaxing activity of Hyssopus officinalis essential oil on isolated intestinal preparations. 2002 Planta Med. pmid:11914956
Niinemets U et al. Stomatal constraints may affect emission of oxygenated monoterpenoids from the foliage of Pinus pinea. 2002 Plant Physiol. pmid:12428002
Rolseth V et al. Additive toxicity of limonene and 50% oxygen and the role of glutathione in detoxification in human lung cells. 2002 Toxicology pmid:11750085
Miyazawa M et al. Sex differences in the metabolism of (+)- and (-)-limonene enantiomers to carveol and perillyl alcohol derivatives by cytochrome p450 enzymes in rat liver microsomes. 2002 Chem. Res. Toxicol. pmid:11800592
Asamoto M et al. Mammary carcinomas induced in human c-Ha-ras proto-oncogene transgenic rats are estrogen-independent, but responsive to d-limonene treatment. 2002 Jpn. J. Cancer Res. pmid:11802805
Miyazawa M et al. Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes. 2002 Drug Metab. Dispos. pmid:11950794
Yaghmur A et al. Furfural-cysteine model reaction in food grade nonionic oil/water microemulsions for selective flavor formation. 2002 J. Agric. Food Chem. pmid:11982414
Gäfvert E et al. Free radicals in antigen formation: reduction of contact allergic response to hydroperoxides by epidermal treatment with antioxidants. 2002 Br. J. Dermatol. pmid:11966698
Lücker J et al. Monoterpene biosynthesis in lemon (Citrus limon). cDNA isolation and functional analysis of four monoterpene synthases. 2002 Eur. J. Biochem. pmid:12084056
Villar D and Carson TL Chlorpyrifos poisoning over-looked as potential diagnosis. 2002 J. Am. Vet. Med. Assoc. pmid:12369686
Pino JA et al. Volatile compounds of Psidium salutare (H.B.K.) Berg. fruit. 2002 J. Agric. Food Chem. pmid:12188621
Klenø JG et al. Degradation of the adsorbent Tenax TA by nitrogen oxides, ozone, hydrogen peroxide, OH radical, and limonene oxidation products. 2002 Environ. Sci. Technol. pmid:12380084
Stull JO et al. A comparative analysis of glove permeation resistance to paint stripping formulations. 2002 Jan-Feb AIHA J (Fairfax, Va) pmid:11843429
Ozaki M et al. Perception of noxious compounds by contact chemoreceptors of the blowfly, Phormia regina: putative role of an odorant-bindingpProtein. 2003 Chem. Senses pmid:12771021
Rogers JV et al. Gene expression in rat skin induced by irritating chemicals. 2003 J. Biochem. Mol. Toxicol. pmid:12815608
El Tamer MK et al. Domain swapping of Citrus limon monoterpene synthases: impact on enzymatic activity and product specificity. 2003 Arch. Biochem. Biophys. pmid:12623068
Raphael TJ and Kuttan G Immunomodulatory activity of naturally occurring monoterpenes carvone, limonene, and perillic acid. 2003 Immunopharmacol Immunotoxicol pmid:12784919
Pino JA et al. Characterization of volatiles in bullock's heart (Annona reticulata L.) fruit cultivars from Cuba. 2003 J. Agric. Food Chem. pmid:12797752
Jirovetz L et al. Composition, quality control, and antimicrobial activity of the essential oil of long-time stored dill (Anethum graveolens L.) seeds from Bulgaria. 2003 J. Agric. Food Chem. pmid:12797755
Librando V et al. OH-initiated oxidation of monoterpenes: reaction of alpha-pinene. 2003 Ann Chim pmid:12817640
Njoroge SM et al. Changes of the volatile profile and artifact formation in Daidai (Citrus aurantium) cold-pressed peel oil on storage. 2003 J. Agric. Food Chem. pmid:12822942
Souza MC et al. Evaluation of anti-inflammatory activity of essential oils from two Asteraceae species. 2003 Pharmazie pmid:12967039
Saito Y et al. Solubilization of (+)-limonene by anionic/cationic mixed surfactant systems. 2003 Drug Dev Ind Pharm pmid:12741615
Duetz WA et al. Biotransformation of limonene by bacteria, fungi, yeasts, and plants. 2003 Appl. Microbiol. Biotechnol. pmid:12743755
Wilkins CK et al. Upper airway irritation of terpene/ozone oxidation products (TOPS). Dependence on reaction time, relative humidity and initial ozone concentration. 2003 Toxicol. Lett. pmid:12749814
Parija T and Das BR Involvement of YY1 and its correlation with c-myc in NDEA induced hepatocarcinogenesis, its prevention by d-limonene. 2003 Mol. Biol. Rep. pmid:12688534
Choi HS Character impact odorants of Citrus Hallabong [(C. unshiu Marcov x C. sinensis Osbeck) x C. reticulata Blanco] cold-pressed peel oil. 2003 J. Agric. Food Chem. pmid:12696958
Santos-Gomes PC and Fernandes-Ferreira M Essential oils produced by in vitro shoots of sage (Salvia officinalis L.). 2003 J. Agric. Food Chem. pmid:12670167
Weiss ER et al. Isolation and identification of terpene chlorohydrins found in cold-pressed orange oil. 2003 J. Agric. Food Chem. pmid:12670170
Spernath A et al. Self-diffusion nuclear magnetic resonance, microstructure transitions, and solubilization capacity of phytosterols and cholesterol in Winsor IV food-grade microemulsions. 2003 J. Agric. Food Chem. pmid:12670181
Heydorn S et al. Fragrance allergy in patients with hand eczema - a clinical study. 2003 Contact Derm. pmid:14531870
Fang JY et al. In vitro and in vivo evaluations of the efficacy and safety of skin permeation enhancers using flurbiprofen as a model drug. 2003 Int J Pharm pmid:12672611
Shiga H et al. Release characteristics of flavor from spray-dried powder in boiling water and during rice cooking. 2003 Biosci. Biotechnol. Biochem. pmid:12729014
Schneider RC et al. Determination of the disproportionation products of limonene used for the catalytic hydrogenation of castor oil. 2003 J Chromatogr A pmid:12580499
Marine SS and Clemons J Determination of limonene oxidation products using SPME and GC-MS. 2003 J Chromatogr Sci pmid:12597594
Tipre DN and Vavia PR Acrylate-based transdermal therapeutic system of nitrendipine. 2003 Drug Dev Ind Pharm pmid:12602494
Angioni A et al. Chemical composition, plant genetic differences, and antifungal activity of the essential oil of Helichrysum italicum G. Don ssp. microphyllum (Willd) Nym. 2003 J. Agric. Food Chem. pmid:12568568
Díaz-Maroto MC et al. Influence of drying on the flavor quality of spearmint (Mentha spicata L.). 2003 J. Agric. Food Chem. pmid:12590466
Pourmortazavi SM et al. Supercritical carbon dioxide extraction of essential oils from Perovskia atriplicifolia Benth. 2003 J. Agric. Food Chem. pmid:12926891
Hendradi E et al. Effect of mixed micelle formulations including terpenes on the transdermal delivery of diclofenac. 2003 Biol. Pharm. Bull. pmid:14646182
Tripathi AK et al. Effect of d-limonene on three stored-product beetles. 2003 J. Econ. Entomol. pmid:12852646
Li T and Wang J [Supercritical carbon dioxide extraction of essential oil from Cinnamomum migao H. W. Li]. 2003 Zhong Yao Cai pmid:12856468
Lu XG et al. [D-limonene induces apoptosis of gastric cancer cells]. 2003 Zhonghua Zhong Liu Za Zhi pmid:12921557
Hug W Virtual enantiomers as the solution of optical activity's deterministic offset problem. 2003 Appl Spectrosc pmid:14610930
Matura M et al. Patch testing with oxidized R-(+)-limonene and its hydroperoxide fraction. 2003 Contact Derm. pmid:14641115
Topham EJ and Wakelin SH D-Limonene contact dermatitis from hand cleansers. 2003 Contact Derm. pmid:14641365
Raphael TJ and Kuttan G Effect of naturally occurring monoterpenes carvone, limonene and perillic acid in the inhibition of experimental lung metastasis induced by B16F-10 melanoma cells. 2003 J. Exp. Clin. Cancer Res. pmid:14582701
Davidson JP and Corey EJ First enantiospecific total synthesis of the antitubercular marine natural product pseudopteroxazole. Revision of assigned stereochemistry. 2003 J. Am. Chem. Soc. pmid:14583045
Ohara K et al. Limonene production in tobacco with Perilla limonene synthase cDNA. 2003 J. Exp. Bot. pmid:14585822
Dekker M et al. Modelling the effect of oil/fat content in food systems on flavour absorption by LLDPE. 2003 Food Addit Contam pmid:12623667
Van Willige RW et al. Influence of flavour absorption by food-packaging materials (low-density polyethylene, polycarbonate and polyethylene terephthalate) on taste perception of a model solution and orange juice. 2003 Food Addit Contam pmid:12519723
Carter OA et al. Monoterpene biosynthesis pathway construction in Escherichia coli. 2003 Phytochemistry pmid:12943759
Wangensteen H et al. Identification of epoxybergamottin as a CYP3A4 inhibitor in grapefruit peel. 2003 Eur. J. Clin. Pharmacol. pmid:12610742
Hata T et al. Induction of apoptosis by Citrus paradisi essential oil in human leukemic (HL-60) cells. 2003 Nov-Dec In Vivo pmid:14758720
Tasdemir D et al. Analysis of the volatile components of five Turkish Rhododendron species by headspace solid-phase microextraction and GC-MS (HS-SPME-GC-MS). 2003 Nov-Dec Z. Naturforsch., C, J. Biosci. pmid:14713153
Nickavar B et al. Chemical composition of the fixed and volatile oils of Nigella sativa L. from Iran. 2003 Sep-Oct Z. Naturforsch., C, J. Biosci. pmid:14577620
Chen F et al. Characterization of a root-specific Arabidopsis terpene synthase responsible for the formation of the volatile monoterpene 1,8-cineole. 2004 Plant Physiol. pmid:15299125
DeWitt C and Bebarta V Botanical solvents. 2004 Clin Occup Environ Med pmid:15325315
Palamakula A et al. Response surface methodology for optimization and characterization of limonene-based coenzyme Q10 self-nanoemulsified capsule dosage form. 2004 AAPS PharmSciTech pmid:15760063
Krishnaiah YS et al. In vitro percutaneous permeability enhancement of nimodipine by limonene across the excised rat abdominal skin. 2004 Pharmazie pmid:15638083
Rastogi SK and Singh J Iontophoretic enhancement of leuprolide acetate by fatty acids, limonene, and depilatory lotions through porcine epidermis. 2004 Pharm Dev Technol pmid:15581070
Vajrabhaya LO et al. Cytotoxicity evaluation of gutta-percha solvents: Chloroform and GP-Solvent (limonene). 2004 Oral Surg Oral Med Oral Pathol Oral Radiol Endod pmid:15583552
Soottitantawat A et al. Effect of water activity on the release characteristics and oxidative stability of D-limonene encapsulated by spray drying. 2004 J. Agric. Food Chem. pmid:14995132
Mahmoud SS et al. Cosuppression of limonene-3-hydroxylase in peppermint promotes accumulation of limonene in the essential oil. 2004 Phytochemistry pmid:15003417
Klenø J and Wolkoff P Changes in eye blink frequency as a measure of trigeminal stimulation by exposure to limonene oxidation products, isoprene oxidation products and nitrate radicals. 2004 Int Arch Occup Environ Health pmid:15007652
Xu Z et al. [Experimental study on inclusion compound of beta-cyclodextrin with limonene]. 2004 Zhong Yao Cai pmid:15524302
Belletti N et al. Evaluation of the antimicrobial activity of citrus essences on Saccharomyces cerevisiae. 2004 J. Agric. Food Chem. pmid:15537299
Choi KY et al. Molecular cloning and identification of a novel oxygenase gene specifically induced during the growth of Rhodococcus sp. strain T104 on limonene. 2004 J. Microbiol. pmid:15357313
Kim NS and Lee DS Headspace solid-phase microextraction for characterization of fragrances of lemon verbena (Aloysia triphylla) by gas chromatography-mass spectrometry. 2004 J Sep Sci pmid:15335064
Reynier A et al. Stabilization of aroma compounds through sorption-release by packaging polymers. 2004 J. Agric. Food Chem. pmid:15373406
Sawamura M et al. Characteristic odor components of Citrus reticulata Blanco (ponkan) cold-pressed oil. 2004 Biosci. Biotechnol. Biochem. pmid:15322352
Uzawa M et al. [Studies on analysis of terpene resin in imported chewing gums]. 2004 Shokuhin Eiseigaku Zasshi pmid:15272602
Reiling KK et al. Mono and diterpene production in Escherichia coli. 2004 Biotechnol. Bioeng. pmid:15236249
Höckelmann C and Jüttner F Volatile organic compound (VOC) analysis and sources of limonene, cyclohexanone and straight chain aldehydes in axenic cultures of Calothrix and Plectonema. 2004 Water Sci. Technol. pmid:15237606
Franz R et al. European survey on post-consumer poly(ethylene terephthalate) (PET) materials to determine contamination levels and maximum consumer exposure from food packages made from recycled PET. 2004 Food Addit Contam pmid:15195474
Monge ME et al. Electronic nose screening of limonene release from multicomponent essential oils encapsulated in pectin gels. 2004 Comb. Chem. High Throughput Screen. pmid:15200381
Golshani S et al. Antinociceptive effects of the essential oil of Dracocephalum kotschyi in the mouse writhing test. 2004 J Pharm Pharm Sci pmid:15144738
Si A et al. Effects of NMDA receptor antagonists on olfactory learning and memory in the honeybee (Apis mellifera). 2004 Pharmacol. Biochem. Behav. pmid:14751445
Nguyen Thanh V et al. Rhodotorula cycloclastica sp. nov., Rhodotorula retinophila sp. nov., and Rhodotorula terpenoidalis sp. nov., three limonene-utilizing yeasts isolated from soil. 2004 FEMS Yeast Res. pmid:15450193
Chemat F et al. High power ultrasound effects on lipid oxidation of refined sunflower oil. 2004 Ultrason Sonochem pmid:15157856