(-)-Limonene

(-)-limonene is a lipid of Prenol Lipids (PR) class. (-)-limonene often locates in Kinetochores.

Cross Reference

Introduction

To understand associated biological information of (-)-Limonene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Limonene

MeSH term MeSH ID Detail
Hypolipoproteinemias D007009 9 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Acute Lung Injury D055371 33 associated lipids
Cataract D002386 34 associated lipids
Asthma D001249 52 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Neuroblastoma D009447 66 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Per page 10 20 | Total 11

PubChem Associated disorders and diseases

What pathways are associated with (-)-Limonene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Limonene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

What lipids are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

What genes are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Limonene

Download all related citations
Per page 10 20 50 100 | Total 1129
Authors Title Published Journal PubMed Link
Rottava I et al. Isolation and screening of microorganisms for R-(+)-limonene and (-)-beta-pinene biotransformation. 2010 Appl. Biochem. Biotechnol. pmid:19950000
Helbing J and Bonmarin M Vibrational circular dichroism signal enhancement using self-heterodyning with elliptically polarized laser pulses. 2009 J Chem Phys pmid:19895025
Igimi H et al. Medical dissolution of gallstones. Clinical experience of d-limonene as a simple, safe, and effective solvent. 1991 Dig. Dis. Sci. pmid:1988264
Wattenberg LW and Coccia JB Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone carcinogenesis in mice by D-limonene and citrus fruit oils. 1991 Carcinogenesis pmid:1988170
Parodi A et al. A comparative study of leukaemia inhibitory factor and interleukin-1alpha intracellular content in a human keratinocyte cell line after exposure to cosmetic fragrances and sodium dodecyl sulphate. 2010 Toxicol. Lett. pmid:19878710
Jiang L et al. Theoretical investigation of the NO₃radical addition to double bonds of limonene. 2009 Int J Mol Sci pmid:19865516
Ferrante M et al. Effect of different penetration enhancers on diclofenac permeation across horse skin. 2010 Vet. J. pmid:19815433
Roberto D et al. Antioxidant activity of limonene on normal murine lymphocytes: relation to H2O2 modulation and cell proliferation. 2010 Basic Clin. Pharmacol. Toxicol. pmid:19796276
Anfora G et al. Synthetic grape volatiles attract mated Lobesia botrana females in laboratory and field bioassays. 2009 J. Chem. Ecol. pmid:19779942
Clarin T et al. Odor detection and odor discrimination in subadult and adult rats for two enantiomeric odorants supported by c-fos data. 2010 Behav. Brain Res. pmid:19766144
Zhou W et al. Sub-chronic effects of s-limonene on brain neurotransmitter levels and behavior of rats. 2009 J. Nutr. Sci. Vitaminol. pmid:19763039
Peng CH et al. Insulin secretagogue bioactivity of finger citron fruit (Citrus medica L. var. Sarcodactylis Hort, Rutaceae). 2009 J. Agric. Food Chem. pmid:19761210
Giraudeau P et al. Multiple ultrafast, broadband 2D NMR spectra of hyperpolarized natural products. 2009 J. Am. Chem. Soc. pmid:19743849
Bateman AP et al. Time-resolved molecular characterization of limonene/ozone aerosol using high-resolution electrospray ionization mass spectrometry. 2009 Phys Chem Chem Phys pmid:19727500
Maksymiuk CS et al. Secondary organic aerosol formation from multiphase oxidation of limonene by ozone: mechanistic constraints via two-dimensional heteronuclear NMR spectroscopy. 2009 Phys Chem Chem Phys pmid:19727487
Singh P et al. Essential oil of Aegle marmelos as a safe plant-based antimicrobial against postharvest microbial infestations and aflatoxin contamination of food commodities. 2009 J. Food Sci. pmid:19723215
Pereira PC et al. Evolution of the yields and composition of essential oil from Portuguese myrtle (Myrtus comunis L.) through the vegetative cycle. 2009 Molecules pmid:19701146
Attygalle AB et al. Orange/lemon-scented beetles: opposite enantiomers of limonene as major constituents in the defensive secretion of related carabids. 2009 Naturwissenschaften pmid:19690825
Begley TH et al. Diffusion behaviour of additives in polypropylene in correlation with polymer properties. 2008 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:19680849
Kourtchev I et al. Characterization of atmospheric aerosols at a forested site in central Europe. 2009 Environ. Sci. Technol. pmid:19673249
SenyiÄŸit T et al. Different approaches for improving skin accumulation of topical corticosteroids. 2009 Int J Pharm pmid:19635541
Oladipupo LA and Adebola OO Chemical composition of the essential oils of the flowers, leaves and stems of two senecio polyanthemoides Sch. Bip. samples from South Africa. 2009 Molecules pmid:19513007
Zhou YY et al. [Analysis of essential oil from the leaves and fruits of Eucalyptus tereticornis in Guangxi province by GC-MS]. 2009 Zhong Yao Cai pmid:19504965
Kim D and Ortiz de Montellano PR Tricistronic overexpression of cytochrome P450cam, putidaredoxin, and putidaredoxin reductase provides a useful cell-based catalytic system. 2009 Biotechnol. Lett. pmid:19458919
Zhou X et al. [Analysis on the volatile oil of Xinhui Pericarpium Citri Reticulatae in different years by GC/MS]. 2009 Zhong Yao Cai pmid:19445115
Padala SR et al. Adsorption of gum Arabic, egg white protein, and their mixtures at the oil-water interface in limonene oil-in-water emulsions. 2009 J. Agric. Food Chem. pmid:19422219
pmid:19412756
Moraes TM et al. Effects of limonene and essential oil from Citrus aurantium on gastric mucosa: role of prostaglandins and gastric mucus secretion. 2009 Chem. Biol. Interact. pmid:19410566
Zhou W et al. Components of lemon essential oil attenuate dementia induced by scopolamine. 2009 Nutr Neurosci pmid:19356307
Menichini F et al. Acetylcholinesterase and butyrylcholinesterase inhibition of ethanolic extract and monoterpenes from Pimpinella anisoides V Brig. (Apiaceae). 2009 Fitoterapia pmid:19351555
Maltzman TH et al. Effects of monoterpenoids on in vivo DMBA-DNA adduct formation and on phase I hepatic metabolizing enzymes. 1991 Carcinogenesis pmid:1934293
Vibenholt A et al. Formation and stability of secondary ozonides from monoterpenes studied by mass spectrometry. 2009 Chemosphere pmid:19329138
Arruda DC et al. Inhibitory activity of limonene against Leishmania parasites in vitro and in vivo. 2009 Biomed. Pharmacother. pmid:19321295
Rhee H et al. Femtosecond characterization of vibrational optical activity of chiral molecules. 2009 Nature pmid:19295604
Vaccaro PH Spectroscopy: Handedness in quick time. 2009 Nature pmid:19295594
Mutalik S et al. A combined approach of chemical enhancers and sonophoresis for the transdermal delivery of tizanidine hydrochloride. 2009 Drug Deliv pmid:19267299
Song YH et al. The effects of terpenes on the permeation of lidocaine and ofloxacin from moisture-activated patches. 2009 Drug Deliv pmid:19267298
Kong JO et al. Nematicidal and Propagation Activities of Thyme Red and White Oil Compounds toward Bursaphelenchus xylophilus (Nematoda: Parasitaphelenchidae). 2007 J. Nematol. pmid:19259493
Charve J and Reineccius GA Encapsulation performance of proteins and traditional materials for spray dried flavors. 2009 J. Agric. Food Chem. pmid:19231860
de Sousa DP et al. Structure and spasmolytic activity relationships of monoterpene analogues found in many aromatic plants. 2008 Nov-Dec Z. Naturforsch., C, J. Biosci. pmid:19227827
Seifert A et al. Rational design of a minimal and highly enriched CYP102A1 mutant library with improved regio-, stereo- and chemoselectivity. 2009 Chembiochem pmid:19222039
Andrade L et al. Modeling of temperature-induced near-infrared and low-field time-domain nuclear magnetic resonance spectral variation: chemometric prediction of limonene and water content in spray-dried delivery systems. 2009 Appl Spectrosc pmid:19215643
Gannu R et al. In vitro permeation of carvedilol through porcine skin: effect of vehicles and penetration enhancers. 2008 Jul-Aug PDA J Pharm Sci Technol pmid:19174954
Young GP and Bush JK Assessment of the allelopathic potential of Juniperus ashei on germination and growth of Bouteloua curtipendula. 2009 J. Chem. Ecol. pmid:19153797
Ferrarini SR et al. Synthesis of limonene beta-amino alcohol derivatives in support of new antileishmanial therapies. 2008 Mem. Inst. Oswaldo Cruz pmid:19148415
Manuele MG et al. Mechanism of the antiproliferative action of limonene on a lymphoma cell line: participation of nitric oxide. antiproliferative action of limonene on a lymphoma cell line. 2009 Phytother Res pmid:19145635
Bråred Christensson J et al. Air oxidation increases skin irritation from fragrance terpenes. 2009 Contact Derm. pmid:19125719
Bicas JL et al. Characterization of monoterpene biotransformation in two pseudomonads. 2008 J. Appl. Microbiol. pmid:19120646
Cheng SS et al. Insecticidal activities of leaf and twig essential oils from Clausena excavata against Aedes aegypti and Aedes albopictus larvae. 2009 Pest Manag. Sci. pmid:19115256
Zhao Y et al. siRNA-targeted COL8A1 inhibits proliferation, reduces invasion and enhances sensitivity to D-limonence treatment in hepatocarcinoma cells. 2009 IUBMB Life pmid:19109829
Christensson JB et al. Limonene hydroperoxide analogues differ in allergenic activity. 2008 Contact Derm. pmid:19076885
Nannapaneni R et al. Campylobacter and Arcobacter species sensitivity to commercial orange oil fractions. 2009 Int. J. Food Microbiol. pmid:19070381
Singh HP et al. Phytotoxicity of major constituents of the volatile oil from leaves of Artemisia scoparia Waldst. & Kit. 2008 Sep-Oct Z. Naturforsch., C, J. Biosci. pmid:19040104
Malhotra S et al. Antioxidant activity of citrus cultivars and chemical composition of Citrus karna essential oil. 2009 Planta Med. pmid:19031367
Guillard EC et al. Molecular interactions of penetration enhancers within ceramides organization: a FTIR approach. 2009 Eur J Pharm Sci pmid:19022378
pmid:19009569
Mansour el-SS et al. Essential oil of Daucus glaber Forssk. 2004 May-Jun Z. Naturforsch., C, J. Biosci. pmid:18998404
Li D et al. Impact of elevated CO2 and O3 concentrations on biogenic volatile organic compounds emissions from Ginkgo biloba. 2009 Bull Environ Contam Toxicol pmid:18974914
Liu T et al. Bioequivalence evaluation of two D-limonene capsule formulations in healthy Chinese volunteers. 2008 Pharmazie pmid:18972832
Crowell PL et al. Selective inhibition of isoprenylation of 21-26-kDa proteins by the anticarcinogen d-limonene and its metabolites. 1991 J. Biol. Chem. pmid:1894647
Bateman AP et al. The effect of solvent on the analysis of secondary organic aerosol using electrospray ionization mass spectrometry. 2008 Environ. Sci. Technol. pmid:18939568
Nannapaneni R et al. Antimicrobial activity of commercial citrus-based natural extracts against Escherichia coli O157:H7 isolates and mutant strains. 2008 Foodborne Pathog. Dis. pmid:18851678
Kumar P et al. Kinetics of enzyme inhibition by active molluscicidal agents ferulic acid, umbelliferone, eugenol and limonene in the nervous tissue of snail Lymnaea acuminata. 2009 Phytother Res pmid:18814203
Nakamura A et al. Odour of limonene affects feeding behaviour in the blowfly, Phormia regina. 2008 Neurosci. Lett. pmid:18809464
Jonsson AM et al. Influence of OH scavenger on the water effect on secondary organic aerosol formation from ozonolysis of limonene, Delta3-carene, and alpha-pinene. 2008 Environ. Sci. Technol. pmid:18767648
Ferrarini SR et al. Acaricidal activity of limonene, limonene oxide and beta-amino alcohol derivatives on Rhipicephalus (Boophilus) microplus. 2008 Vet. Parasitol. pmid:18755549
Wolkoff P et al. Acute airway effects of ozone-initiated d-limonene chemistry: importance of gaseous products. 2008 Toxicol. Lett. pmid:18723085
Surratt JD et al. Organosulfate formation in biogenic secondary organic aerosol. 2008 J Phys Chem A pmid:18710205
Mang SA et al. Contribution of carbonyl photochemistry to aging of atmospheric secondary organic aerosol. 2008 J Phys Chem A pmid:18700731
Manuele MG et al. Effect of Tilia x viridis flower extract on the proliferation of a lymphoma cell line and on normal murine lymphocytes: contribution of monoterpenes, especially limonene. 2008 Phytother Res pmid:18688792
Wilson MJ et al. The effect of dietary supplementation with limonene or myo-inositol on the induction of neoplasia and matrix metalloproteinase and plasminogen activator activities in accessory sex organs of male Lobund-Wistar rats. 2008 Exp. Mol. Pathol. pmid:18675799
Vergunst H et al. In vitro comparison of different gall stone dissolution solvents. 1991 Gut pmid:1864544
Johansson S et al. Carbon- and oxygen-centered radicals are equally important haptens of allylic hydroperoxides in allergic contact dermatitis. 2008 Chem. Res. Toxicol. pmid:18597496
Miller JA et al. Determination of d-limonene in adipose tissue by gas chromatography-mass spectrometry. 2008 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:18571481
Bicas JL et al. Optimization of R-(+)-alpha-terpineol production by the biotransformation of R-(+)-limonene. 2008 J. Ind. Microbiol. Biotechnol. pmid:18560915
Satomi Y et al. Production of the monoterpene limonene and modulation of apoptosis-related proteins in embryonic-mouse NIH 3T3 fibroblast cells by introduction of the limonene synthase gene isolated from Japanese catnip (Schizonepeta tenuifolia). 2009 Biotechnol. Appl. Biochem. pmid:18547169
pmid:18541135
Krishnaiah YS et al. Studies on optimizing in vitro transdermal permeation of ondansetron hydrochloride using nerodilol, carvone, and limonene as penetration enhancers. 2008 Pharm Dev Technol pmid:18484486
Virot M et al. Green procedure with a green solvent for fats and oils' determination. Microwave-integrated Soxhlet using limonene followed by microwave Clevenger distillation. 2008 J Chromatogr A pmid:18471820
pmid:18470566
pmid:18416899
Guarneri F et al. Allergic contact dermatitis and asthma caused by limonene in a labourer handling citrus fruits. 2008 Contact Derm. pmid:18416769
Lim PF et al. Physicochemical effects of terpenes on organogel for transdermal drug delivery. 2008 Int J Pharm pmid:18406084
Djordjevic D et al. Chemical and physical stability of protein and gum arabic-stabilized oil-in-water emulsions containing limonene. 2008 J. Food Sci. pmid:18387094
Merino V et al. Enhancement of nortriptyline penetration through human epidermis: influence of chemical enhancers and iontophoresis. 2008 J. Pharm. Pharmacol. pmid:18380912
Chandrashekar NS and Hiremath SR In vivo immunomodulatory, cumulative skin irritation, sensitization and effect of d-limonene on permeation of 6-mercaptopurine through transdermal drug delivery. 2008 Biol. Pharm. Bull. pmid:18379058
Bisson JF et al. Anti-inflammatory senescence actives 5203-L molecule to promote healthy aging and prolongation of lifespan. 2008 Rejuvenation Res pmid:18370605
Karlberg AT et al. Animal experiments on the allergenicity of d-limonene--the citrus solvent. 1991 Ann Occup Hyg pmid:1836319
Papadimitriou V et al. Biocompatible microemulsions based on limonene: formulation, structure, and applications. 2008 Langmuir pmid:18303927
Ben-Yehoshua S et al. Involvement of limonene hydroperoxides formed after oil gland injury in the induction of defense response against Penicillium digitatum in lemon fruit. 2008 J. Agric. Food Chem. pmid:18298064
Walser ML et al. High-resolution mass spectrometric analysis of secondary organic aerosol produced by ozonation of limonene. 2008 Phys Chem Chem Phys pmid:18259641
pmid:18253798
Baik JS et al. Chemical composition and biological activities of essential oils extracted from Korean endemic citrus species. 2008 J. Microbiol. Biotechnol. pmid:18239420
Krishnaiah YS and Al-Saidan SM Limonene enhances the in vitro and in vivo permeation of trimetazidine across a membrane-controlled transdermal therapeutic system. 2008 Curr Drug Deliv pmid:18220554
Kamphoff M et al. Influence of different extraction parameters on a solid-phase dynamic extraction for the gas chromatographic determination of d-limonene degradation products by using a fractional factorial design. 2007 Nov-Dec J AOAC Int pmid:18193739
Takiguchi N et al. Performance of mice in discrimination of liquor odors: behavioral evidence for olfactory attention. 2008 Chem. Senses pmid:18178544
Sun J D-Limonene: safety and clinical applications. 2007 Altern Med Rev pmid:18072821
Yang JE et al. Cloning of four genes involved in limonene hydroxylation from Enterobacter cowanii 6L. 2007 J. Microbiol. Biotechnol. pmid:18051329
Dambolena JS et al. Inhibitory effect of cyclic terpenes (limonene, menthol, menthone and thymol) on Fusarium verticillioides MRC 826 growth and fumonisin B1 biosynthesis. 2008 Toxicon pmid:18037463
Wang Y et al. Comparative analysis of essential oil components in Pericarpium Citri Reticulatae Viride and Pericarpium Citri Reticulatae by GC-MS combined with chemometric resolution method. 2008 J Pharm Biomed Anal pmid:17942260