(-)-Limonene

(-)-limonene is a lipid of Prenol Lipids (PR) class. (-)-limonene often locates in Kinetochores.

Cross Reference

Introduction

To understand associated biological information of (-)-Limonene, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Limonene

MeSH term MeSH ID Detail
Acute Lung Injury D055371 33 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Neuroblastoma D009447 66 associated lipids
Hypolipoproteinemias D007009 9 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Cataract D002386 34 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 | Total 11

PubChem Associated disorders and diseases

What pathways are associated with (-)-Limonene

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Limonene?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

What lipids are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

What genes are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with (-)-Limonene?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Limonene

Download all related citations
Per page 10 20 50 100 | Total 1129
Authors Title Published Journal PubMed Link
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Crowell PL et al. Identification of metabolites of the antitumor agent d-limonene capable of inhibiting protein isoprenylation and cell growth. 1992 Cancer Chemother. Pharmacol. pmid:1464157
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Karlberg AT et al. Air oxidation of d-limonene (the citrus solvent) creates potent allergens. 1992 Contact Derm. pmid:1395597
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Jonker D et al. Acute (24 hr) toxicity of a combination of four nephrotoxicants in rats compared with the toxicity of the individual compounds. 1993 Food Chem. Toxicol. pmid:8095245
Reicks MM and Crankshaw D Effects of D-limonene on hepatic microsomal monooxygenase activity and paracetamol-induced glutathione depletion in mouse. 1993 Xenobiotica pmid:8237062
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Karlberg AT et al. Hydroperoxides in oxidized d-limonene identified as potent contact allergens. 1994 Arch. Dermatol. Res. pmid:8154930
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Chander SK et al. Effectiveness of combined limonene and 4-hydroxyandrostenedione in the treatment of NMU-induced rat mammary tumours. 1994 Br. J. Cancer pmid:8180018
Haag JD and Gould MN Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene. 1994 Cancer Chemother. Pharmacol. pmid:7923558
Friedman MI et al. Limonene in expired lung air of patients with liver disease. 1994 Dig. Dis. Sci. pmid:8050315
Hard GC and Whysner J Risk assessment of d-limonene: an example of male rat-specific renal tumorigens. 1994 Crit. Rev. Toxicol. pmid:7945892
Crowell PL and Gould MN Chemoprevention and therapy of cancer by d-limonene. 1994 Crit Rev Oncog pmid:7948106
Crowell PL et al. Human metabolism of the experimental cancer therapeutic agent d-limonene. 1994 Cancer Chemother. Pharmacol. pmid:7987974
Koyama Y et al. Comparative analysis of percutaneous absorption enhancement by d-limonene and oleic acid based on a skin diffusion model. 1994 Pharm. Res. pmid:8008702
Lehman-McKeeman LD and Caudill D d-Limonene induced hyaline droplet nephropathy in alpha 2u-globulin transgenic mice. 1994 Fundam Appl Toxicol pmid:7532604
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Karlberg AT et al. Influence of an anti-oxidant on the formation of allergenic compounds during auto-oxidation of d-limonene. 1994 Ann Occup Hyg pmid:8210084
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Luján HD et al. Isoprenylation of proteins in the protozoan Giardia lamblia. 1995 Mol. Biochem. Parasitol. pmid:8538683
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Hursting SD et al. Chemoprevention of spontaneous tumorigenesis in p53-knockout mice. 1995 Cancer Res. pmid:7664260
Hohl RJ and Lewis K Differential effects of monoterpenes and lovastatin on RAS processing. 1995 J. Biol. Chem. pmid:7615555
Rosenbaum MR and Kerlin RL Erythema multiforme major and disseminated intravascular coagulation in a dog following application of a d-limonene-based insecticidal dip. 1995 J. Am. Vet. Med. Assoc. pmid:7591926
Ohara N et al. Combined effect of d-limonene pretreatment and temperature on the rat skin permeation of lipophilic and hydrophilic drugs. 1995 Biol. Pharm. Bull. pmid:7550099
Yamane MA et al. Terpene penetration enhancers in propylene glycol/water co-solvent systems: effectiveness and mechanism of action. 1995 J. Pharm. Pharmacol. pmid:8932680
Gelb MH et al. The inhibition of protein prenyltransferases by oxygenated metabolites of limonene and perillyl alcohol. 1995 Cancer Lett. pmid:7767906
Miyazaki S et al. Percutaneous absorption of indomethacin from pluronic F127 gels in rats. 1995 J. Pharm. Pharmacol. pmid:7674126
Kristiansen E and Madsen C Induction of protein droplet (alpha 2 mu-globulin) nephropathy in male rats after short-term dosage with 1,8-cineole and l-limonene. 1995 Toxicol. Lett. pmid:7482582
Touvay C et al. Effect of limonene and sobrerol on monocrotaline-induced lung alterations and pulmonary hypertension. 1995 May-Jun Int. Arch. Allergy Immunol. pmid:7542078
Von Burg R Limonene. 1995 Nov-Dec J Appl Toxicol pmid:8603937
Adam KP et al. Partial purification and characterization of a monoterpene cyclase, limonene synthase, from the liverwort Ricciocarpos natans. 1996 Arch. Biochem. Biophys. pmid:8806745
Karlson J et al. Inhibition of tumor cell growth by monoterpenes in vitro: evidence of a Ras-independent mechanism of action. 1996 Anticancer Drugs pmid:8826611
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Alvares K et al. Ciprofibrate represses alpha 2u-globulin expression in liver and inhibits d-limonene nephrotoxicity. 1996 Carcinogenesis pmid:8625456
Jansen LA and Jongen WM The use of initiated cells as a test system for the detection of inhibitors of gap junctional intercellular communication. 1996 Carcinogenesis pmid:8625460
Kawamori T et al. Inhibitory effects of d-limonene on the development of colonic aberrant crypt foci induced by azoxymethane in F344 rats. 1996 Carcinogenesis pmid:8625465
Kimura J et al. Lack of chemoprevention effects of the monoterpene d-limonene in a rat multi-organ carcinogenesis model. 1996 Jpn. J. Cancer Res. pmid:8766522
Poon GK et al. Identification and characterization of limonene metabolites in patients with advanced cancer by liquid chromatography/mass spectrometry. 1996 Drug Metab. Dispos. pmid:8723738
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Morse MA and Toburen AL Inhibition of metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by limonene. 1996 Cancer Lett. pmid:8665490
Saito K et al. Alpha 2u-globulins in the urine of male rats: a reliable indicator for alpha 2u-globulin accumulation in the kidney. 1996 Toxicology pmid:8571386
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Crowell PL et al. Antitumorigenic effects of limonene and perillyl alcohol against pancreatic and breast cancer. 1996 Adv. Exp. Med. Biol. pmid:8886131
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Ariazi EA and Gould MN Identifying differential gene expression in monoterpene-treated mammary carcinomas using subtractive display. 1996 J. Biol. Chem. pmid:8910589
Whysner J and Williams GM d-limonene mechanistic data and risk assessment: absolute species-specific cytotoxicity, enhanced cell proliferation, and tumor promotion. 1996 Pharmacol. Ther. pmid:8910952
Huang J et al. [GC-MS analysis of essential oils from the pericarps of Illicium majus Hook.f.et. Thoms. and I. micranthum Dunn]. 1996 Zhongguo Zhong Yao Za Zhi pmid:9812698
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Chang YC et al. Allergic contact dermatitis from oxidized d-limonene. 1997 Contact Derm. pmid:9455646
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Savithiry N et al. Production of alpha-terpineol from Escherichia coli cells expressing thermostable limonene hydratase. 1997 Appl. Biochem. Biotechnol. pmid:9170246
Nakaizumi A et al. d-Limonene inhibits N-nitrosobis(2-oxopropyl)amine induced hamster pancreatic carcinogenesis. 1997 Cancer Lett. pmid:9233838
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Karlberg AT and Dooms-Goossens A Contact allergy to oxidized d-limonene among dermatitis patients. 1997 Contact Derm. pmid:9165203
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Kunta JR et al. Effect of menthol and related terpenes on the percutaneous absorption of propranolol across excised hairless mouse skin. 1997 J Pharm Sci pmid:9423148
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Chen X et al. Inhibition of farnesyl protein transferase by monoterpene, curcumin derivatives and gallotannin. 1997 Jul-Aug Anticancer Res. pmid:9252680
Crowell PL Monoterpenes in breast cancer chemoprevention. 1997 Nov-Dec Breast Cancer Res. Treat. pmid:9478274
Zhao K and Singh J Mechanisms of percutaneous absorption of tamoxifen by terpenes: eugenol, D-limonene and menthone. 1998 J Control Release pmid:9795076
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